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2023
Meshrif Alruily, Sameh Abd El-Ghany, A. M. M. M. E., and A. A. Abd El-Aziz, "A-Tuning Ensemble Machine Learning Technique for Cerebral Stroke Prediction", Applied Sciences, vol. 13, no. 8, pp. 5047–5066, 2023. Abstract
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, "Accepting Living Kidney Donors with Preexisting Diabetes Mellitus A Perspective on the Recent OPTN Policy Change—July 2022", Clinical Journal of American Society of Nephrology , vol. 18, issue 1, pp. 127 - 129, 2023.
Edrees, A., O. Hassanein, O. Shaalan, and A. Yassen, "Accuracy of high definition near infrared transillumination camera in detection of hidden proximal caries", Journal of Clinical and Experimental Dentistry, vol. 15, issue 1, no. 1, pp. e1–e8, 2023. Abstract59413.pdfWebsite

Background: Early caries detection became mandatory in modern dentistry. However, the traditional methods in caries detection had many limitations. Hence, a novel approach based on Near Infrared technology was introduced to overcome such limitations. Material and methods: Proximal surfaces of 102 posterior teeth from 36 adult participants who fulfilled the eligibility criteria were assessed by two examiners using three diagnostic methods. Teeth were examined visually according to the criteria of the International Caries Detection and Assessment System (ICDAS-II) then examined by bitewing digital radiograph (BW) and near infrared light transillumination (NIRT) camera (Vista Proxi iX HD smart). Inter and intra observer agreements were assessed using Kappa test. Diagnostic accuracy parameters and Area Under the ROC curve (AUROC) with 95% confidence interval (95% CI) were evaluated for the different caries assessment methods. Results: The results of inter-observer agreement showed an excellent agreement in the different groups. There was a statistically significant difference in the score distribution between ICDASII and VistaCam modalities (P-value <0.05). While there was no statistically significant difference in the score distribution between bitewing radiography and VistaCam modalities (P-value >0.05). ROC curve analysis revealed that VistaCam when compared with ICDASII had sensitivity (99.0%), specificity (50.0 %), diagnostic accuracy (98.0%) and Area under the ROC curve (AUC) was 0.745 with 95% Confidence Interval (0.649 - 0.826). When VistaCam compared with bitewing radiography, it showed sensitivity (100.0%); specificity (40.0%), diagnostic accuracy (97.1%) and AUC (0.700) with 95% confidence interval (0.601 - 0.787). Conclusions: NIRT based diagnostic modality is a promising method for detection of hidden proximal lesions overcoming the hazards of radiograph. Key words:Bitewing radiography , ICDAS II , Near-infrared transillumination, proximal caries, VistaCam® iX Proxi.

Hasanin, A., N. Karam, M. Mostafa, A. Abdelnasser, W. Hamimy, A. Z. Fouad, akram eladawy, and ahmed lotfy, "THE ACCURACY OF INFERIOR VENA CAVA DISTENSIBILITY THROUGH THE TRANSHEPATIC APPROACH TO PREDICT FLUID RESPONSIVENESS IN PATIENTS WITH SEPTIC SHOCK AFTER EMERGENCY LAPAROTOMY.", Shock (Augusta, Ga.), vol. 60, issue 4, pp. 560-564, 2023. Abstract

Background: We aimed to evaluate the ability of inferior vena cava (IVC) distensibility using the transhepatic approach to predict fluid responsiveness in mechanically ventilated patients with septic shock after emergency laparotomy. Methods: This prospective observational study included mechanically ventilated paralyzed adult who had septic shock after emergency laparotomy. The IVC dimensions were measured through the transhepatic and subxiphoid approaches. The fluid responsiveness was confirmed with >15% increase in cardiac output after 500 mL of fluid bolus. The outcomes were the ability of transhepatic (primary outcome) and subxiphoid approach to predict fluid responders using the area under the receiver operating characteristics curve analysis. The gray zone for the two approaches was calculated. Results: Data from 51 patients were analyzed, and the number of fluid responders was 30 of 52 (58%). The transhepatic approach was feasible in all patients, whereas the subxiphoid approach was only feasible in 42 patients. The area under the receiver operating characteristics curve (95% confidence interval) for the transhepatic IVC distensibility was 0.88 (0.76-0.95), and it was comparable with that of the subxiphoid approach (0.81 [0.66-0.92], P = 0.417). The gray zone for the transhepatic IVC distensibility was 17% to 35% including 24 of 51 patients (47%), whereas the gray zone for the subxiphoid IVC distensibility was 13% to 34% including 18 of 42 patients (43%). Conclusion: In conclusion, the transhepatic approach for evaluation of IVC distensibility showed good accuracy in predicting fluid responsiveness in patients with septic shock after emergency laparotomy. The transhepatic approach showed the same accuracy as the subxiphoid approach with the advantage of being feasible in larger number of patients.

Azzazi, Y., M. M. Korany, and E. A. El-Nabarawy, "Acral Speckled Hypomelanosis: A Case Report and a Review of Literature.", The American Journal of dermatopathology, vol. 45, issue 6, pp. 397-399, 2023. Abstract

BACKGROUND: Acral speckled hypomelanosis is a very rare pigmentation disorder that appears early in life with hypopigmented macules on background of normal skin, occurring on the acral parts.

CASE REPORT: We report a 9-year-old female patient with a 3-year duration of progressive, hypopigmented, confetti-like macules occurring symmetrically on the dorsum of both hands and feet. Biopsy showed normal number of melanocytes with no evidence of macromelanosomes using special stains for melanocytes.

CONCLUSION: Acral speckled hypomelanosis is a relatively, recently, discovered entity, with only 9 cases reported to date, and our case is the 10th. The exact etiopathogenesis is not yet known.

Mostafa, H. I. A., "Action spectrum for reorientations in bacteriorhodopsin of purple membrane in suspension", Scientific Reports, vol. 13, no. 1, 2023. Abstract
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Salem, A. A., M. H. Ismail, and A. S. Ibrahim, "Active Reconfigurable Intelligent Surface-Assisted MISO Integrated Sensing and Communication Systems for Secure Operation", IEEE Transactions on Vehicular Technology, vol. 72, issue 4, pp. 4919 – 4931, 2023.
Khalil, A. M., O. M. Sabry, H. E. I. Askary, S. M. El Zalabani, and N. m Fayek, "Acylated polyphenolics of family Fabaceae: distribution, chemodiversity, and bioactivity, a comprehensive review", International Journal of Food Science and Technology, vol. 58, issue 3, pp. 1028-1036https://doi.org/10.1111/ijfs.16271, 2023. int_j_of_food_sci_tech_-_2022_-_khalil_-_acylated_polyphenolics_of_family_fabaceae__distribution__chemodiversity__and.pdf
Khalil, A. M., O. M. Sabry, H. E. I. Askary, S. M. El Zalabani, and N. m Fayek, "Acylated polyphenolics of family Fabaceae: distribution, chemodiversity, and bioactivity, a comprehensive review", International Journal of Food Science and Technology, vol. 58, issue 3, pp. 1028-1036https://doi.org/10.1111/ijfs.16271, 2023. int_j_of_food_sci_tech_-_2022_-_khalil_-_acylated_polyphenolics_of_family_fabaceae__distribution__chemodiversity__and.pdf
Khalil, A. M., O. M. Sabry, H. E. I. Askary, S. M. El Zalabani, and N. m Fayek, "Acylated polyphenolics of family Fabaceae: distribution, chemodiversity, and bioactivity, a comprehensive review", International Journal of Food Science and Technology, vol. 58, issue 3, pp. 1028-1036https://doi.org/10.1111/ijfs.16271, 2023. int_j_of_food_sci_tech_-_2022_-_khalil_-_acylated_polyphenolics_of_family_fabaceae__distribution__chemodiversity__and.pdf
Mohamed, M., L. F. Ibrahim, K. ELMenshawy, and H. R. Fadlallah, "Adaptive Learning Systems based on ILOs of Courses", WSEAS Transactions on Systems and Control, vol. 18, pp. 1-17, 2023. AbstractWebsite

Nowadays, the use of e-learning techniques and methods is a very important challenge due to the
importance of digital transformation to all countries. Firstly, the spread of the COVID-19 virus all over the world.
Secondly, all students need to study their courses remotely from home to reduce the communication with others to
save their life. All teachers need to engage their students effectively to study an online course, get more knowledge
and high results at the end of these courses. Data mining is the best tool used to find a hidden pattern. We used an
educational data mining tool to help teachers find the pros and cons of using an e-learning course with their
students. We need to classify students on these online courses according to their ability to understand materials and
quizzes, or assessment methods of the course, by making adaptive e-learning courses. In this paper, we will show
the importance of using adaptive e-learning courses and the challenges faced by authors to build these systems, and
we will list the different methods used with adaptive learning like gamification, brain-hex models, facial emotions,
and we will also list a survey about other authors' techniques and methods used to find the student's learner style.
We build a new proposed model of ILOs(Intended Learning Outcomes) adaptive learning with the emotion-based
system to let the system find the student's learning style and build the material according to their skills and
knowledge outcomes from the course and engage the use of facial emotion while taking the quiz to predict the
student's results and the topics he/she needs to study more via our system to achieve high grades and knowledge.
Our system finds that the visual students have the highest grades with 75%, followed by kinesthetic with 70% and
the lowest grades in auditory with 50%.

El-Harith, M. A., R. M. Abdelazeem, O. Hamdy, and Z. Abdel-Salam, "Adaptive optics-based wavefront-enhanced laser-induced fluorescence (WELIF) for improved analytical performance", Analytical Methods, vol. 15, issue 2, pp. 212-220, 2023.
Alnaghy, E., S. Taman, E. Abdelhalim, A. Abdel Razek, M. El-Shabrawi, M. Ezz El Regal, A. Megahed, S. Elzeny, and N. El Tantawi, "The added value of brain MR spectroscopy in children with Crigler-Najjar syndrome type-I: correlation with demographic, neurodevelopmental, and laboratory findings.", The British journal of radiology, vol. 96, issue 1144, pp. 20220433, 2023. Abstract

OBJECTIVE: The aim of this study is to demonstrate the role of proton magnetic resonance spectroscopy (1H-MRS) in the detection of brain microstructural changes in patients with Crigler-Najjar syndrome type-I (CNs-I), and its correlation with demographic, neurodevelopmental and laboratory findings.

METHODS: Prospective study was conducted on 25 children with CNs-I and 25 age and sex-matched children, who served as control. They underwent multivoxel 1H-MRS of basal ganglion at echo time 135-144 ms. N-acetyl aspartate/Creatine (NAA/Cr) and Choline (Ch)/Cr were calculated and correlated with demographic, clinical, and laboratory findings of patients with CNs-I.

RESULTS: There was a significant difference in NAA/Cr and Ch/Cr between patients and controls. The cut-off value for NAA/Cr and Ch/Cr used to differentiate patients from controls were 1.8 and 1.2 with an area under the curve (AUC) of 0.91 and 0.84 respectively. There was a significant difference in MRS ratios between patients with neurodevelopmental delay (NDD) and patients without NDD. The cut-off values for NAA/Cr and Ch/Cr used to differentiate between patients with NDD and patients without NDD were 1.47 and 0.99, with AUC of 0.87 and 0.8 respectively. The NAA/Cr and Ch/Cr were well correlated with family history ( = 0.006 and < 0.001) respectively, consanguinity ( < 0.001 and = 0.001), neurodevelopmental delay ( = 0.001 and = 0.004), serum bilirubin level ( = -0.77, < 0.001), ( = -0.49, = 0.014), phototherapy ( < 0.001 and = 0.32), blood transfusion ( < 0.001 and = 0.001) respectively.

CONCLUSION: 1H-MRS can be a useful tool in the detection of neurological changes in patients with CNs-I; NAA/Cr and Ch/Cr parameters are well correlated with demographic, clinical, and laboratory findings.

ADVANCES IN KNOWLEDGE: Our study is the first report on using MRS in assessing neurological manifestations in CNs. 1H-MRS can be a useful tool in the detection of neurological changes in patients with CNs-I.

Rabie, M. A., H. I. Ibrahim, N. N. Nassar, and R. M. Atef, "Adenosine A receptor agonist, N6-cyclohexyladenosine, attenuates Huntington's disease via stimulation of TrKB/PI3K/Akt/CREB/BDNF pathway in 3-nitropropionic acid rat model.", Chemico-biological interactions, vol. 369, pp. 110288, 2023. Abstract

Huntington's disease (HD) is an inherited neurodegenerative disease characterized by progressive motor, behavioral, and cognitive impairments. Intrastriatal injection of 3- nitropropionic acid (3NP) was used to induce HD-like symptoms by inhibiting succinate dehydrogenase enzyme (SDH) in the mitochondrial complex II. The adenosine A receptor has long been known to have a crucial role in neuroprotection, mainly by blocking Ca influx, which causes inhibition of glutamate (Glu) and a decline in its excitatory effects at the postsynaptic level. To this end, this study investigated the possible involvement of TrKB/PI3K/Akt/CREB/BDNF pathway in mediating protection afforded by the central N6-cyclohexyladenosine (CHA), an adenosine A receptor agonist. A single intrastriatal CHA injection (6.25 nM/1 μL); 45min after 3-NP injection, attenuated neuronal death, and improved cognitive and motor deficits caused by 3-NP neurotoxin. This effect was shown to parallel an enhanced activation of PI3K/Akt/CREB/BDNF axis as well as boosting pERK levels. Moreover, CHA attenuated neuroinflammatory and oxidative stress status via reducing NFκB p65, TNFα and iNOS contents and increasing SOD. Furthermore, immunohistochemical data showed a reduction in the glial fibrillary acidic protein (GFAP) immunoreactivity to a marker for astrocyte and microglia activation following CHA treatment. The results of this study suggest that CHA may have protective effect against HD via modulating oxidative stress, excitotoxic and inflammatory pathways.

AbdelWahed, A. S., A. A. Abu-Musa, H. Moubarak, and H. Badawy, "THE ADOPTION OF BIG DATA ANALYTICS IN THE EXTERNAL AUDITING: Bibliometric and Content Analyses", International Journal of Auditing and Accounting Studies, 2023.
N.S, S., H. Zedan, A. Hesham, M. Fawz, E. Diab, A. S. Yassin, and M. Abu-Elghait, "Advanced approaches for endotoxin detection and removal from snake antivenoms.", Toxicon, vol. 222, pp. 107003, 2023.
Li, H. X., U. A. - R. Hussein, I. Waleed, S. H. Z. Al-Abdeen, F. M. A. Altalbawy, Z. H. Adhab, A. Faisal, M. Y. Alshahrani, H. K. Zaidan, M. Suliman, et al., "An advanced computational method for studying drug nanonization using green supercritical-based processing for improvement of pharmaceutical bioavailability in aqueous media", Journal of Molecular Liquids, vol. 381, pp. 121805, 2023. 712da7d864ab86379c89a3078673a94d.pdf
Abdelwahab, M. B. M., and I. M. A. Helal, "Advanced Techniques for Business Process Automation: Insights and Challenges", 2023 Intelligent Methods, Systems, and Applications (IMSA): IEEE, pp. 303–308, 2023. Abstract
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Soliman, M., A. Eskander, Hassan Effat, T. Fayad, and T. E. Gohary, "Adverse Cardiovascular Events in Post‑Renal Transplant Patients, a Retrospective Study of Five Hundred Cases Over Twenty‑Two Years", Current Transplantation Reports, issue https://doi.org/10.1007/s40472-023-00399-0, 2023.
Tawfik, A. M., "Air Vessel Sizing Approach for Pipeline Protection Using Artificial Neural Networks", Journal of Engineering and Applied Science, 2023.
Hassaan, G. A., and M. Abdelmageed, "Aircraft pitch control using feedback PD and first-order compensators", World Journal of Engineering Research and technology, vol. 9, issue 11, pp. 49-59, 2023. 2023_sircraftpitchcontrol.pdf
Hmmam, I., M. O. H. A. M. E. D. A. B. D. E. L. - S. H. A. K. U. R. ALI, and A. Abdellatif, "Alginate-Based Zinc Oxide Nanoparticles Coating Extends Storage Life and Maintains Quality Parameters of Mango Fruits “cv. Kiett”", Coatings, vol. 13, issue 2: MDPI, pp. 362, 2023. Abstract
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Hmmam, I., M. O. H. A. M. E. D. A. B. D. E. L. - S. H. A. K. U. R. ALI, and A. Abdellatif, "Alginate-Based Zinc Oxide Nanoparticles Coating Extends Storage Life and Maintains Quality Parameters of Mango Fruits “cv. Kiett”", Coatings, vol. 13, no. 2: MDPI, pp. 362, 2023. Abstract

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