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In Press
Elawar, A., G. Sayed, N. Ibrahim, and W. Abdelrahman, Assessment of metabolic syndrome in rheumatoid arthritis patients and its realtion to disease activity, , Cairo, Cairo university, In Press.
Taha, S., and H. Mostafa, "Accelerated Software Implementation of Authenticated Encryption Stream Ciphers for High Speed Applications ", IEEE International Conference on Microelectronics (ICM 2019), Cairo, Egypt, In Press.
Aly, A. A., N. A. Saleh, and M. A. Mahmoud, "An adaptive EWMA control chart for monitoring zero-inflated Poisson processes", Communications in Statistics-Simulation and Computation, pp. 1-14, In Press.
Safan, M., A. Aboudina, and D. Shawky, "An Approach to investigate the effectiveness of multi-task learning", The 16th International Computer Engineering Conference (ICENCO), Cairo, Egypt, In Press.
Atef, F., M. H. Zaky, N. K. Ahmed, M. A. Messiha, O. T. Abdelwahab, A. A. Farid, O. M. Selim, and H. Mostafa, "Automated Current Mirror Layout (ACML) Tool", IEEE International Conference on Microelectronics (ICM 2019), Cairo, Egypt, In Press.
2104
Hussein, R. S., and M. Mourad, "The Adoption of technological Innovations in a Service Context: an Empirical Study on the Higher Education in Egypt", Journal of Business and Industrial Marketing, vol. 29, issue 6, pp. 525-545, 2104.
2023
Edrees, A., O. Hassanein, O. Shaalan, and A. Yassen, "Accuracy of high definition near infrared transillumination camera in detection of hidden proximal caries", Journal of Clinical and Experimental Dentistry, vol. 15, issue 1, no. 1, pp. e1–e8, 2023. Abstract59413.pdfWebsite

Background: Early caries detection became mandatory in modern dentistry. However, the traditional methods in caries detection had many limitations .Hence, a novel approach based on Near Infrared technology was introduced to overcome such limitations. Material and Methods: Proximal surfaces of 102 posterior teeth from 36 adult participants who fulfilled the eligibility criteria were assessed by two examiners using three diagnostic methods. Teeth were examined visually according to the criteria of the International Caries Detection and Assessment System (ICDAS-II) then examined by bitewing digital radiograph (BW) and near infrared light transillumination (NIRT) camera (Vista Proxi iX HD smart). Inter and intra observer agreements were assessed using Kappa test. Diagnostic accuracy parameters and Area Under the ROC curve (AUROC) with 95% confidence interval (95% CI) were evaluated for the different caries assessment methods. Results: The results of inter-observer agreement showed an excellent agreement in the different groups. There was a statistically significant difference in the score distribution between ICDASII and VistaCam modalities (P-value <0.05) .While there was no statistically significant difference in the score distribution between bitewing radiography and VistaCam modalities (P-value >0.05). ROC curve analysis revealed that VistaCam when compared with ICDASII had sensitivity (99.0%), specificity (50.0 %), diagnostic accuracy (98.0%) and Area under the ROC curve (AUC) was 0.745 with 95% Confidence Interval (0.649-0.826).When VistaCam compared with bitewing radiography , it showed sensitivity (100.0%); specificity (40.0%), diagnostic accuracy (97.1%) and AUC (0.700) with 95% confidence interval (0.601-0.787). Conclusions: NIRT based diagnostic modality is a promising method for detection of hidden proximal lesions overcoming the hazards of radiograph.

Hassan, A. S., A. W. Shawki, and H. Z. Muhammed, "Analysis of Household Income, Expenditure and Consumption Survey Research Data for North Sinai Governorate in Egypt Using Length Biased Truncated Lomax Distribution", STATISTICS, OPTIMIZATION AND INFORMATION COMPUTING, 2023.
Farghaly, T. A., M. F. Harras, A. M. R. Alsaedi, H. A. Thakir, H. K. Mahmoud, and D. F. Katowah, "Antiviral Activity of Pyrimidine Containing Compounds: Patent Review", Mini-review in medicinal Chemistry , 2023.
Kotb, M. A., H. Abd El Baky, S. Sayed, M. A. Komy, M. Onsy, A. Aly, A. Tamer, and E. Mohamed, "Autosomal Recessive Polycystic Kidney Disease in a Child Complicated by Autoimmune Hemolytic Anemia: A Case Report", Pediatric Sciences Journal, vol. 3, issue 1, pp. 67-71, 2023.
El-Ghany, W. A. A., "Avian cellulitis: A skin affection associated with economic losses in broiler chickens.", Online Journal of Animal and Feed Research, vol. 13, issue 1, pp. 34-38., 2023. ojafr_131_34-38_2023.pdf
2022
Agaiby, S. S., and S. M. Ahmed, "Assessing the Nonlinear Load-Deformation Relationships of Vertically Loaded Shallow Foundations on Clays using the Seismic Piezocone Testing", 20th International Conference on Soil Mechanics and Geotechnical Engineering, Sydney, Australia , 3 May, 2022.
Sial, T. A., S. M. Shaheen, Z. Lan, P. K. Korai, M. I. Ghani, M. N. Khan, A. -ul- A. Syed, M. N. Hussain Asghar Ali, I. Rajpar, M. Memon, et al., "Addition of walnut shells biochar to alkaline arable soil caused contradictory effects on CO2 and N2O emissions, nutrients availability, and enzymes activity", Chemosphere, vol. 293, pp. 133476, 2022. AbstractWebsite

Mitigation of greenhouse gas (GHGs) emissions and improving soil health using biochar (BC) shall help achieving the UN-Sustainable Development Goals. The impacts of walnut shells biochar (WSB) pyrolyzed at different temperatures on CO2 and N2O emission and soil health have not been yet sufficiently explored. We investigated the effects of addition of WSB pyrolyzed at either 300 °C (WSB-300), 450 °C (WSB-450), or at 600 °C (WSB-600) to alkaline soil on CO2 and N2O emissions, nutrients availability, and soil enzymes activities in a 120-day incubation experiment. Cumulative N2O emissions were reduced significantly as compared to the control, by 64.9%, 50.6%, and 36.4% after WSB-600, WSB-450 and WSB-300, respectively. However, the cumulative CO2 emissions increased, over the control, as follows: WSB-600 (50.7%), WSB-450 (68.6%), and WSB-300 (73.4%). Biochar addition, particularly WSB-600 significantly increased soil pH (from 8.1 to 8.34), soil organic C (SOC; from 8.6 to 22.3 g kg−1), available P (from 21.0 to 60.5 mg kg−1), and K (181.0–480.5 mg kg−1), and activities of urease, alkaline phosphatase, and invertase. However, an opposite pattern was observed with NH4+, NO3−, total N and β-glucosidase activity after WSB application. The WBS produced from high temperature pyrolysis can be used for N2O emissions mitigation and improvement of soil pH, SOC, available P and K, and activities of urease, alkaline, phosphatase. However, WBS produced from low temperature pyrolysis can be used to promote N availability and β-glucosidase; however, these findings should be verified under different field and climatic conditions.

Hassan, S. A., N. W. Nashat, M. R. Elghobashy, S. S. Abbas, and A. A. Moustafa, Advanced chemometric methods as powerful tools for impurity profiling of drug substances and drug products: Application on bisoprolol and perindopril binary mixture, , vol. 267: Elsevier, pp. 120576, 2022. Abstract
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Elfiky, A. A., E. B. Azzam, and M. W. Shafaa, "The anti-HCV, Sofosbuvir, versus the anti-EBOV Remdesivir against SARS-CoV-2 RNA dependent RNA polymerase in silico", Molecular Diversity, vol. 26, issue 1, pp. 171 - 181, 2022. Abstract
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Mohammed, A. A. B., A. Mohamed, N. E. - A. El-Naggar, H. Mahrous, G. M. Nasr, A. Abdella, R. H. Ahmed, S. Irmak, M. S. A. Elsayed, S. Selim, et al., "Antioxidant and Antibacterial Activities of Silver Nanoparticles Biosynthesized by Moringa oleifera through Response Surface Methodology", Journal of Nanomaterials, vol. 2022: Hindawi, pp. 9984308, 2022. AbstractWebsite

The research highlights the environmentally sustainable biosynthesis of silver nanoparticles from fresh leaves of the herbal medicinal plant Moringa oleifera. They may have been used as anti-inflammatory, anticancer, and antimicrobial agents. M. oleifera extract both reduces and stabilizes silver nanoparticles (AgNPs). Optimum factors needed for AgNP biosynthesis were studied using a central composite design (CCD) matrix. Ultraviolet-visible (UV–Vis) absorption spectroscopy, transmission electron microscopy, and Fourier-transform infrared spectroscopy were used to confirm and characterize the synthesized AgNPs. The biogenic AgNPs demonstrated substantial antibacterial potential against the pathogenic strains Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Bacillus subtilis. The antioxidant activity of biosynthesized AgNPs with M. oleifera extract increased from 11.96% when the concentration of the extract was 4 mg/mL to 63.79% at a plant concentration of 20 mg/mL. This research provides an easy and cost-effective technique for the production of stable nanoparticles, with an evaluation of their bioactivity.

Mohammed, A. A. B., A. Mohamed, N. E. - A. El-Naggar, H. Mahrous, G. M. Nasr, A. Abdella, R. H. Ahmed, S. Irmak, M. S. A. Elsayed, S. Selim, et al., "Antioxidant and Antibacterial Activities of Silver Nanoparticles Biosynthesized by Moringa oleifera through Response Surface Methodology", Journal of Nanomaterials, vol. 2022: Hindawi, pp. 9984308, 2022. AbstractWebsite

The research highlights the environmentally sustainable biosynthesis of silver nanoparticles from fresh leaves of the herbal medicinal plant Moringa oleifera. They may have been used as anti-inflammatory, anticancer, and antimicrobial agents. M. oleifera extract both reduces and stabilizes silver nanoparticles (AgNPs). Optimum factors needed for AgNP biosynthesis were studied using a central composite design (CCD) matrix. Ultraviolet-visible (UV–Vis) absorption spectroscopy, transmission electron microscopy, and Fourier-transform infrared spectroscopy were used to confirm and characterize the synthesized AgNPs. The biogenic AgNPs demonstrated substantial antibacterial potential against the pathogenic strains Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, and Bacillus subtilis. The antioxidant activity of biosynthesized AgNPs with M. oleifera extract increased from 11.96% when the concentration of the extract was 4 mg/mL to 63.79% at a plant concentration of 20 mg/mL. This research provides an easy and cost-effective technique for the production of stable nanoparticles, with an evaluation of their bioactivity.

Abdelqader, A. A., E. M. Abdelsalam, Y. A. Attia, M. Moselhy, A. Ali, A. H. Arisha, and M. Samer, Application of Helium-Neon Red Laser for Increasing Biohydrogen Production from Anaerobic Digestion of Biowastes, , vol. 65, issue 1, pp. 11 - 17, 2022. AbstractWebsite

Biohydrogen has significant feasibility since biological processes are much less energy intensive compared with electrolysis and thermo-chemical processes. It is widely recognized that considerable amounts of hydrogen (H2) can be produced from renewable resources without using energy from fossil fuels. Biological processes and bacterial fermentation are considered as the most environmentally friendly alternatives for satisfying future hydrogen demand. Biohydrogen production from agricultural and agro-industrial solid waste and wastewater is considered as highly advantageous as materials of this kind are abundant, cheap and biodegradable. The combustion of H2 with oxygen produces water as its only product: Unlike other fuels, the combustion of H2 does not produce carbon dioxide (CO2), carbon monoxide (CO), nitrogen oxides (NOx), sulfur dioxide (SO2), hydrocarbons or particulate matter (PM). Therefore, hydrogen is an environmentally friendly fuel where endeavors focus on producing specially designed internal combustion engines that can use H2 as fuel. The results showed that laser irradiated inoculum increased biohydrogen production by 1.2 times of the control. Therefore, in this research, it was hypothesized that exposing purple non-sulfur bacterial (PNSB) mix consortium to Helium-Neon red laser for 2 hours increased cell activity and consequently the biohydrogen production from food wastes through photo-fermentation process.

Abdrabo, K. I., M. Saber, S. A. Kantoush, T. ElGharbawi, T. Sumi, and B. Elboshy, "Applications of Remote Sensing for Flood Inundation Mapping at Urban Areas in MENA Region: Case Studies of Five Egyptian Cities", Applications of Space Techniques on the Natural Hazards in the MENA Region: Springer, pp. 307 - 330, 2022. Abstract
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Dawood, M. F. A., A. M. Abu-Elsaoud, M. R. Sofy, H. I. MOHAMED, and M. H. Soliman, "Appraisal of kinetin spraying strategy to alleviate the harmful effects of UVC stress on tomato plants", Environmental Science and Pollution Research, 2022. AbstractWebsite

Abstract Increasing ultraviolet (UV) radiation is causing oxidative stress that accounts for growth and yield losses in the present era of climate change. Plant hormones are useful tools for minimizing UV-induced oxidative stress in plants, but their putative roles in protecting tomato development under UVC remain unknown. Therefore, we investigated the underlying mechanism of pre-and post-kinetin (Kn) treatments on tomato plants under UVC stress. The best dose of Kn was screened in the preliminary experiments, and this dose was tested in further experiments. UVC significantly decreases growth traits, photosynthetic pigments, protein content, and primary metabolites (proteins, carbohydrates, amino acids) but increases oxidative stress biomarkers (lipid peroxidation, lipoxygenase activity, superoxide anion, hydroxyl radical, and hydrogen peroxide) and proline content. Treatment of pre-and post-kinetin spraying to tomato plants decreases UVC-induced oxidative stress by restoring the primary and secondary metabolites’ (phenolic compounds, flavonoids, and anthocyanins) status and upregulating the antioxidant defense systems (non-enzymatic antioxidants as ascorbate, reduced glutathione, α-tocopherol as well as enzymatic antioxidants as superoxide dismutase, catalase, ascorbate peroxidase, glutathione peroxidase, glutathione-S-transferase, and phenylalanine ammonia-lyase). Thus, the application of Kn in optimum doses and through different modes can be used to alleviate UVC-induced negative impacts in tomato plants.

Graphical abstract

Mohamed Ibrahim, O., N. Al Mazrouei, A. Z. Al Meslamani, A. B. Kassem, N. A. El-Bassiouny, S. B. Mohammed Ebaed, and R. M. Ibrahim, "Assessment of a new strategy for catalyzing deprescribing in community pharmacies", Journal of the American Pharmacists Association, vol. 62, issue 1, pp. 125 - 133, 2022. AbstractWebsite

Background: Although community pharmacists have been actively engaged in patient care, their role in deprescribing is still restricted. Objectives: This study aimed to assess the effectiveness of a new educational approach designed to catalyze deprescribing in community pharmacies. Methods: In this 4-month, randomized, controlled trial, 108 community pharmacies in Egypt were randomly and equally distributed to either the active or the control groups. Participants from the active group pharmacies received 31 deprescribing-related clinical case scenarios, designed according to the available deprescribing guideline and clinical experiences of an expert panel members, and delivered through WhatsApp. Then participants from both groups reported the incidence of potentially inappropriate medicines (PIMs), the frequency of deprescribing opportunities, and related pharmacist interventions. Results: Pharmacists from the active group reported a considerably higher incidence of PIMs (20.87%) than that reported by pharmacists from the control group (5.03%). In addition, they made 1326 deprescribing-related interventions, of which 1022 (77.07%) were accepted and 641 (48.34%) were significant interventions. The proportions of cessation of drug therapy, reducing the dose, and persuasion of patients to accept deprescribing pharmacist interventions in the active group were 37.85%, 22.09%, and 10.63%, respectively. In contrast, 150 of 268 deprescribing-related interventions (55.97%) in the active group were accepted. The clinical value and type of deprescribing decision were statistically significant determinants for the acceptance of deprescribing decisions. The mean time needed to persuade the patient about deprescribing and the cost saved per patient across the active and the control groups were 5.09 ± 3.54 minutes versus 10.03 ± 6.19 minutes and 17.88 ± 9.60 U.S. dollars versus 4.49 ± 2.44 U.S. dollars, respectively. Conclusion: The intervention proposed improved the frequency and clinical value of deprescribing decisions. © 2022 American Pharmacists Association®