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2023
Rabie, M. A., H. I. Ibrahim, N. N. Nassar, and R. M. Atef, "Adenosine A receptor agonist, N6-cyclohexyladenosine, attenuates Huntington's disease via stimulation of TrKB/PI3K/Akt/CREB/BDNF pathway in 3-nitropropionic acid rat model.", Chemico-biological interactions, vol. 369, pp. 110288, 2023. Abstract

Huntington's disease (HD) is an inherited neurodegenerative disease characterized by progressive motor, behavioral, and cognitive impairments. Intrastriatal injection of 3- nitropropionic acid (3NP) was used to induce HD-like symptoms by inhibiting succinate dehydrogenase enzyme (SDH) in the mitochondrial complex II. The adenosine A receptor has long been known to have a crucial role in neuroprotection, mainly by blocking Ca influx, which causes inhibition of glutamate (Glu) and a decline in its excitatory effects at the postsynaptic level. To this end, this study investigated the possible involvement of TrKB/PI3K/Akt/CREB/BDNF pathway in mediating protection afforded by the central N6-cyclohexyladenosine (CHA), an adenosine A receptor agonist. A single intrastriatal CHA injection (6.25 nM/1 μL); 45min after 3-NP injection, attenuated neuronal death, and improved cognitive and motor deficits caused by 3-NP neurotoxin. This effect was shown to parallel an enhanced activation of PI3K/Akt/CREB/BDNF axis as well as boosting pERK levels. Moreover, CHA attenuated neuroinflammatory and oxidative stress status via reducing NFκB p65, TNFα and iNOS contents and increasing SOD. Furthermore, immunohistochemical data showed a reduction in the glial fibrillary acidic protein (GFAP) immunoreactivity to a marker for astrocyte and microglia activation following CHA treatment. The results of this study suggest that CHA may have protective effect against HD via modulating oxidative stress, excitotoxic and inflammatory pathways.

Ibrahim, H. I., M. A. Rabie, R. M. Atef, and N. N. Nassar, "Adenosine A1 receptor agonist, N6-cyclohexyladenosine, attenuates Huntington's disease via stimulation of TrKB/PI3K/Akt/CREB/BDNF pathway in 3-nitropropionic acid rat model", Chemico-Biological Interactions, vol. 369, pp. 110288, 2023.
Ezzat, A. A. M., M. O. H. A. M. E. D. A. H. M. E. D. EISSA, and M. E. Shimy, "Adjacent Segment Degeneration Following Laminectomy Versus Degeneration without Laminectomy in Levels Adjacent to those Operated Upon by Lumbar Posterolateral Fixation: A Comparative Study", Medical Journal of Cairo University, vol. 91, issue 09, pp. 1213-1218, 2023.
Ruscitti, P., J. Sota, A. Vitale, G. Lopalco, F. Iannone, M. Morrone, H. A. M. Giardini, M. A. D'Agostin, I. P. de Brito Antonelli, and I. Almaghlouth, "The administration of methotrexate in patients with Still's disease,“real-life” findings from AIDA Network Still Disease Registry", Seminars in arthritis and rheumatism, vol. 62: WB Saunders, pp. 152244, 2023. Abstract
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AbdelWahed, A. S., A. A. Abu-Musa, H. Moubarak, and H. Badawy, "THE ADOPTION OF BIG DATA ANALYTICS IN THE EXTERNAL AUDITING: Bibliometric and Content Analyses", International Journal of Auditing and Accounting Studies, 2023.
Eltaweel, R. M., S. Husien, A. I. Salim, N. G. Mostafa, K. Ahmed, I. S. Fahim, L. A. Said, and A. G. Radwan, "Adsorption as an Emerging Technology and Its New Advances of Eco- Friendly Characteristics Isotherm, Kinetic, and Thermodynamic Analysis", Wastewater Treatment Recycling, Management, and Valorization of Industrial Solid Wastes: CRC Press, 2023.
Eltaweel, R. M., S. Husien, A. I. Salim, N. G. Mostafa, K. Ahmed, I. S. Fahim, L. A. Said, and A. G. Radwan, "Adsorption as an Emerging Technology and Its New Advances of Eco-Friendly Characteristics: Isotherm, Kinetic, and Thermodynamic Analysis", Wastewater Treatment: CRC Press, pp. 89-152, 2023. Abstract
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Elashery, S. E. A., M. M. El-Bouraie, E. A. Abdelgawad, N. F. Attia, and G. G. Mohamed, "Adsorptive performance of bentonite-chitosan nanocomposite as a dual antibacterial and reusable adsorbent for Reactive Red 195 and crystal violet removal: kinetic and thermodynamic studies", Biomass Conversion and Biorefinery, 2023.
Yang, L., Y. Gao, V. K. Bajpai, H. A. El-Kammar, J. Simal-Gandara, H. Cao, K. - W. Cheng, M. Wang, R. R. J. Arroo, L. Zou, et al., "Advance toward isolation, extraction, metabolism and health benefits of kaempferol, a major dietary flavonoid with future perspectives.", Critical reviews in food science and nutrition, vol. 63, issue 16, pp. 2773-2789, 2023. Abstract

As a major ubiquitous secondary metabolite, flavonoids are widely distributed in . Among flavonoids, kaempferol is a typical natural flavonol in diets and medicinal plants with myriad bioactivities, such as anti-inflammatory activity, anti-cancer activity, antioxidant activity, and anti-diabetic activity. However, the natural sources, absorption and metabolism as well as the bioactivities of kaempferol have not been reviewed comprehensively and systematically. This review highlights the latest research progress and the effect of kaempferol in the prevention and treatment of various chronic diseases, as well as its protective health effects, and provides a theoretical basis for future research to be used in nutraceuticals. Further, comparison of the different extraction and analytical methods are presented to highlight the most optimum for PG recovery and its detection in plasma and body fluids. Such review aims at improving the value-added applications of this unique dietary bioactive flavonoids at commercial scale and to provide a reference for its needed further development.

Sheraba, N. S., H. Zedan, A. Hesham, M. Fawz, E. Diab, A. S. Yassin, and M. Abu-Elghait, "Advanced approaches for endotoxin detection and removal from snake antivenoms.", Toxicon, vol. 222, pp. 107003, 2023.
Lotfy, H. M., S. S. Saleh, Y. Rostom, R. H. Obaydo, and D. A. Ahmed, "Advanced Approaches in Green Univariate Spectrophotometric Methods", Sustainable Approaches in Pharmaceutical Sciences, pp. 157–215: Wiley , 2023.
Mohamed, H. M., N. M. Ahmed, W. S. Mohamed, and M. G. Mohamed, "Advanced coatings for consolidation of pottery artifacts against deterioration", Journal of Cultural Heritage, vol. 64, pp. 63–72, 2023.
Li, H. X., U. A. - R. Hussein, I. Waleed, S. H. Z. Al-Abdeen, F. M. A. Altalbawy, Z. H. Adhab, A. Faisal, M. Y. Alshahrani, H. K. Zaidan, M. Suliman, et al., "An advanced computational method for studying drug nanonization using green supercritical-based processing for improvement of pharmaceutical bioavailability in aqueous media", Journal of Molecular Liquids, vol. 381, pp. 121805, 2023. 712da7d864ab86379c89a3078673a94d.pdf
Li, H. X., U. A. - R. Hussein, I. Waleed, S. H. Z. Al-Abdeen, F. M. A. Altalbawy, and Z. H. Adhab, "An advanced computational method for studying drug nanonization using green supercritical-based processing for improvement of pharmaceutical bioavailability in aqueous media", Journal of Molecular Liquids, vol. 381, pp. 121805, 2023. 712da7d864ab86379c89a3078673a94d.pdf
Atta, A. G., W. M. Abd-Elhameed, G. M. Moatimid, and Y. H. Youssri, "Advanced shifted sixth-kind Chebyshev tau approach for solving linear one-dimensional hyperbolic telegraph type problem", Mathematical Sciences, vol. 17, no. 4, pp. 415 – 429, 2023. AbstractWebsite
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Darweish, E., H. M. Marzouk, Y. M. Fayez, and M. S. Eissa, "Advanced Spectrophotometric Resolution Techniques for a Spectrally Overlapping Spasmolytic Binary Mixture along with Dichloroaniline as a Toxic Impurity: Application to Content Uniformity Testing", Journal of AOAC INTERNATIONAL, vol. 106, issue 1, pp. 14-25, 2023.
El-Sharkawy, L., F. Gharib, A. Sedrak, M. Youssef, and A. El-Antably, "Advanced stage laryngeal cancer in Egypt: Quality of life in the scope", Egyptian Journal of Ear, Nose, Throat and Allied Sciences, 2023.
Abdelwahab, M. B. M., and I. M. A. Helal, "Advanced Techniques for Business Process Automation: Insights and Challenges", 2023 Intelligent Methods, Systems, and Applications (IMSA): IEEE, pp. 303–308, 2023. Abstract
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Sanjha Mangrio, Aneela Tahira, A. S. C. I. A. M. M. M., A. A. Shah, S. S. Medany, and E. D. L. M. A. S. E. M. M. B. V. Z. H. I. A., Ayman Nafady, "Advanced Urea Precursors Driven NiCo2O4 Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications", Biosensors, vol. 13, issue 4, pp. 444, 2023.
Soliman, M., A. Eskander, Hassan Effat, T. Fayad, and T. E. Gohary, "Adverse Cardiovascular Events in Post‑Renal Transplant Patients, a Retrospective Study of Five Hundred Cases Over Twenty‑Two Years", Current Transplantation Reports, issue https://doi.org/10.1007/s40472-023-00399-0, 2023.
Abdelrahman, A. R., A. K. Yousef, and N. Abd-Alsabour, "AN AFFORDABLE SMART PRODUCT FOR PERFORMING ALL THE DAILY TASKS BLIND PEOPLE NEED", Journal of Southwest Jiaotong University, vol. 58, issue 4, pp. 120-132, 2023.
Dabbous, AO, El Bohy, Z., Helal, A., and H. S. Hamdy, "Age effects on frequency amplitude ratio of cVEMP.", EJO, vol. 39, issue 28, pp. 1-12, 2023. age_effects_on_frequency_amplitude_ratio_of_cvemp.pdfWebsite
Ali, N. B., R. A. El-Shiekh, R. M. Ashour, S. H. El-Gayed, and E. Abdel-Sattar, "Agro-Food Waste: Harnessing the Potential Significance of Natural Biofilm Inhibitors.", Tropical Journal of Natural Product Research, vol. 7, no. 12, 2023. Abstract
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R.A. Badawy, Ashgan M. Aly, Y. A. E. - F. I. H. H. M., and M. S. Abbas, "Agronomical and nutritional responses of some faba bean (Vicia faba L.) genotypes to organic fertilization under sandy soil conditions", Egypt. J. Plant Breed., vol. 27, no. 1: 10.12816/EJPB.2023.278174, pp. 1–24, 2023. Abstract
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