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Zabady, M. K., M. R. Abdin-Bey, M. M. Hassieb, and M. F. Al-Salman, "Gigantic Cutaneous Myxoma at Equine Distal Limb", Journal of Equine Veterinary Science, vol. 32, issue 10, pp. 624–627, 2012. AbstractWebsite

An extremely large-sized neogrowth of myxoma was observed at the cannon region in a 3-year-old Arabian mare. The mass developed during the course of 4 months. The mass mechanically hindered the animal movement, exposing the mare to multiple external injuries and subsequent blood loss. The clinical parameters, morphology, and hematological and histopathological examinations of the myxoma were recorded. The body condition score of the mare was 1. The hemogram revealed moderate to severe degree of anemia. Histopathological sections assessed after surgical removal identified the mass as a myxoma. To the authors’ knowledge, this is the first report of cutaneous myxoma at equine limb in an Arabian horse.

Zacharakis, E., F. De Luca, A. A. Raheem, G. Garaffa, N. Christopher, A. Muneer, and D. J. Ralph, "Early insertion of a malleable penile prosthesis in ischaemic priapism allows later upsizing of the cylinders.", Scandinavian journal of urology, pp. 1-4, 2015 Jun 26. Abstract

OBJECTIVE: Early insertion of a penile prosthesis in prolonged ischaemic priapism is easier to perform than late prosthesis placement, and preserves the penile length. The aim of this study was to assess whether a delayed exchange to an inflatable implant allows upsizing of the cylinders in patients who have undergone early insertion for refractory ischaemic priapism.

MATERIALS AND METHODS: Over a 30 month period, 10 patients with ischaemic priapism underwent an early insertion of a malleable penile prosthesis. The mean age was 41.3 years and the mean duration of priapism was 188 h. Following a median period of 130.5 days, all of these patients underwent exchange of the malleable to an inflatable prosthesis.

RESULTS: At the time of penile implant exchange, a median upsize in the length of the cylinders of 1 cm in either one or both corporal bodies (range 0-3 cm) was recorded. Five patients had deliberate downsizing at the initial operation owing to a previous shunt. The mean score on the five-item International Index of Erectile Function (IIEF-5) before insertion of the malleable prosthesis was 24 (range 20-25). Three months after the initial insertion of a malleable penile implant the satisfaction rate according to the IIEF-5 score was 80%. Three months after the exchange, the patient satisfaction rate increased to 90%.

CONCLUSION: Insertion of a malleable penile prosthesis is an acceptable option for patients with refractory ischaemic priapism. Although some patients deliberately have a shorter implant inserted initially owing to a previous distal shunt procedure, following a period of resolution the cylinders can be upsized at a later operation.

Zacharakis, E., G. Garaffa, A. A. Raheem, A. N. Christopher, A. Muneer, and D. J. Ralph, "Penile prosthesis insertion in patients with refractory ischaemic priapism: early vs delayed implantation.", BJU international, vol. 114, issue 4, pp. 576-81, 2014 Oct. Abstract

OBJECTIVE: To compare the long-term results of early and delayed insertion of a penile prosthesis (PP) in men with refractory ischaemic priapism (IP).

PATIENTS AND METHODS: Early insertion of a PP was carried out in 68 men with IP within a median of 7 days from the onset of priapism, while 27 had delayed insertion after a median of 5 months. The results for sexual ability, satisfaction and subjective penile shortening were assessed by questioning at follow-up visits.

RESULTS: In the early group, a malleable and an inflatable PP were implanted in 64 and four patients, respectively. After a median follow-up of 17 months, six patients needed revision surgery due to infection and curvature. Patient's satisfaction rate and ability to have sexual intercourse was 96%. In the delayed group, a malleable PP was inserted in 12 patients and an inflatable in the remaining 15. In all, 80% of the patients required a second corporotomy and downsized cylinders due to dense fibrosis. After a median follow-up of 21 months,seven patients required revision surgery due to infection,erosion and mechanical failure. In all, 25 patients were able to engage in sexual intercourse but the satisfaction rate was only 60% mainly due to significant penile shortening.

CONCLUSIONS: Early PP implantation should be the preferred option inpatients with IP, as the procedure is technically easier, has less complication rates and allows greater preservation of penile length.

Zacharakis, E., A. Abdelraheem, A. Freeman, A. Skolarikos, G. Garaffa, A. N. Christopher, A. Muneer, and D. J. Ralph, "The efficacy of the T-shunt procedure and intracavernous tunneling (snake maneuver) for refractory ischemic priapism.", The Journal of urology, vol. 191, issue 1, pp. 164-8, 2014 Jan. Abstract

PURPOSE: The current management of ischemic priapism that is refractory to conventional medical therapy is a form of shunt procedure that diverts blood away from the corpus cavernosum. We assessed the outcome of the T-shunt and intracavernous tunneling for the management of ischemic priapism.

MATERIALS AND METHODS: During a 36-month period 45 patients presented with prolonged ischemic priapism. Patients were divided into subgroups according to the duration of priapism. All patients had an unsuccessful primary treatment, and underwent a T-shunt and intracavernous tunneling with cavernous muscle biopsies. All patients completed an IIEF-5 (International Index of Erectile Function-5) questionnaire preoperatively and 6 months postoperatively.

RESULTS: Resolution of the priapism using a T-shunt and snake maneuver occurred in all patients with a priapism duration of less than 24 hours and in only 30% of those with priapism lasting more than 48 hours. After a 6-month median followup the IIEF-5 score was significantly reduced from a mean of 24 (range 23 to 25) preoperatively to 7.7 (range 5 to 24), which was related to the duration of the priapism (p <0.0005). All patients with priapism for more than 48 hours had necrotic cavernous smooth muscle on biopsy and had severe erectile dysfunction requiring the insertion of a penile prosthesis. Those patients with moderate and mild erectile dysfunction were treated with phosphodiesterase type 5 inhibitors.

CONCLUSIONS: The success of the T-shunt with snake tunneling is dependent on the duration of priapism. When it is less than 24 hours the results are favorable, although erectile dysfunction is still present in 50% of patients. In those with a priapism duration greater than 48 hours the technique usually fails to resolve the priapism and all patients end up with erectile dysfunction due to smooth muscle necrosis.

Zackman, J. A., "A framework for information system architecture", IBM Systems Journal, vol. 26, pp. 267–292, 1987. Abstract
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Zafar, A., M. Raheel, M. Q. Zafar, K. S. Nisar, M. S. Osman, R. N. Mohamed, and A. Elfasakhany, "Dynamics of Different Nonlinearities to the Perturbed Nonlinear Schrödinger Equation via Solitary Wave Solutions with Numerical Simulation", fractal and fractional, vol. 5, pp. 213, 2021.
Zafer, M. M., M. Amin, H. El Mahallawy, M. S. E. - D. Ashour, and M. Al Agamy, "First report of NDM-1-producing Pseudomonas aeruginosa in Egypt.", International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, vol. 29, pp. 80-1, 2014 Dec. Abstract

This work reports the occurrence of New Delhi metallo-beta-lactamase 1 (NDM-1) in metallo-beta-lactamase-producing Pseudomonas aeruginosa in Egypt for the first time, and the presence of more than one blaMBL gene in carbapenem-resistant P. aeruginosa.

Zafer, M. M., M. H. Al-Agamy, H. A. El-Mahallawy, M. A. Amin, and M. S. E. - D. Ashour, "Antimicrobial resistance pattern and their beta-lactamase encoding genes among Pseudomonas aeruginosa strains isolated from cancer patients.", BioMed research international, vol. 2014, pp. 101635, 2014. Abstract

This study was designed to investigate the prevalence of metallo-β-lactamases (MBL) and extended-spectrum β -lactamases (ESBL) in P. aeruginosa isolates collected from two different hospitals in Cairo, Egypt. Antibiotic susceptibility testing and phenotypic screening for ESBLs and MBLs were performed on 122 P. aeruginosa isolates collected in the period from January 2011 to March 2012. MICs were determined. ESBLs and MBLs genes were sought by PCR. The resistant rate to imipenem was 39.34%. The resistance rates for P. aeruginosa to cefuroxime, cefoperazone, ceftazidime, aztreonam, and piperacillin/tazobactam were 87.7%, 80.3%, 60.6%, 45.1%, and 25.4%, respectively. Out of 122 P. aeruginosa, 27% and 7.4% were MBL and ESBL, respectively. The prevalence of bla(VIM-2), bla(OXA-10(-)), bla(VEB-1), bla(NDM(-)), and bla(IMP-1)-like genes were found in 58.3%, 41.7%, 10.4%, 4.2%, and 2.1%, respectively. GIM-, SPM-, SIM-, and OXA-2-like genes were not detected in this study. OXA-10-like gene was concomitant with VIM-2 and/or VEB. Twelve isolates harbored both OXA-10 and VIM-2; two isolates carried both OXA-10 and VEB. Only one strain contained OXA-10, VIM-2, and VEB. In conclusion, bla(VIM-2)- and bla(OXA-10)-like genes were the most prevalent genes in P. aeruginosa in Egypt. To our knowledge, this is the first report of bla(VIM-2), bla(IMP-1), bla(NDM), and bla(OXA-10) in P. aeruginosa in Egypt.

Zafer, M. M., M. H. Al-Agamy, H. A. El-Mahallawy, M. A. Amin, and S. El Din Ashour, "Dissemination of VIM-2 producing Pseudomonas aeruginosa ST233 at tertiary care hospitals in Egypt.", BMC infectious diseases, vol. 15, pp. 122, 2015. Abstract

BACKGROUND: Pseudomonas aeruginosa is an important nosocomial pathogen, commonly causing infections in immunocompromised patients. The aim of this study was to examine the genetic relatedness of metallo-beta-lactamase (MBL) producing carbapenem resistant Pseudomonas aeruginosa clinical isolates collected from 2 tertiary hospitals in Cairo, Egypt using Multi Locus sequence typing (MLST).

METHODS: Phenotypic and genotypic detection of metallo-beta-lactamase for forty eight non-duplicate carbapenem resistant P. aeruginosa isolates were carried out. DNA sequencing and MLST were done.

RESULTS: The bla VIM-2 gene was highly prevalent (28/33 strains, 85%) among 33 MBL-positive P.aeruginosa isolates. MLST revealed eleven distinct Sequence Types (STs). A unique ST233 clone producing VIM-2 was documented by MLST in P.aeruginosa strains isolated from Cairo university hospitals. The high prevalence of VIM-2 producers was not due to the spread of a single clone.

CONCLUSIONS: The findings of the present study clearly demonstrate that clones of VIM-2 positive in our hospitals are different from those reported from European studies. Prevalence of VIM-2 producers of the same clone was detected from surgical specimens whereas oncology related specimens were showing diverse clones.

Zaghla, H., A. Sameer, and undefined, "Arrhythmia in patients with chronic obstructive pulmonary disease", Journal of chest and tuberculosis, 2013.
Zaghla, H., N. Sameer, H. Akabawy, and A. fahmy, "The prognostic effect of statin therapy on endothelial function in patients with early sepsis", The medical journal of Cairo university, vol. 78, issue No 1, 2010.
Zaghla, H., K. Hussien, K. Mashhour, W. Al-Awady, and M. Said, "Myocardial Infarction Following Coronary Artery Bypass Grafting: Prevelance and Factors Affecting The Prognosis", Journal of The Egyptian Society of Cardio-Thoracic Surgery, vol. 21, issue 2, 2013.
Zaghla, H., T. E. Gohary, and A. Alazab, "Thrombocytopenia as aprognostic factor in patients with severe sepsis and multiorgan dyfunction", Cairo university medical journal, 2012.
Zaghlol, H. S., and I. fahmy, "Serum manganese level: Relation to the development of Parkinson like Syndrome.", The Egyptian Journal of Neurology And Psychatry, vol. 3, issue 1, pp. 181-207, 2004.
Zaghlol, H. M., S. F. Mohamed, and H. A. Elgamal, "A comparative study on small industries conducted by women in societies productive families at three governorates.", Research Journal Specific Education , Faculty of Specific Education Mansoura University, vol. 47, 2017. Abstract
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Zaghlol, H. S., M.Hamdy, D. Sabry, and A.Moawad, differentiation between menstrual and peripheral blood stains , , 2017. abstract.pdf
Zaghlol, K. H., M. H. I. Zaki, and M. M., "Assessment and control of nitrite toxicity in clarias gariepinus.", Egyptian J. of Aquat.Biol. and Fish, vol. 11, no. 3, pp. 1047–1068, 2007. Abstract
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Zaghlol, K., S. Sakran, M. El-Sharkawi, and A. Said, "Petrographical, structural, and remote sensing–based mapping of Gebel Atawi area, central Eastern Desert, Egypt", Arabian Journal of Geosciences, vol. 14, pp. Paper No. 1368, 2021.
Zaghlol, H. S., "Does hair provide a permanent marker for diazepam, amitryptline or haloperidol intake in Albino Rats?", The Egyptian Journal of Forensic Sciences and Applied Toxicology, vol. 1, issue 1, pp. 169-185, 2001.
Zaghlol, H. S., "Age Estimation: A Skin Histological Study", The Egyptian Journal of Forensic Sciences and Applied Toxicology, vol. 3, pp. 93-101, 2003.
hossam zaghlol, and A. S. Hosny, "Role of peroneal artery in Lower limb salvage in critical limb ischemia after angioplasty", Kasr El-Aini Journal of Surgery, 2012.
Zaghlol, H. S., "Serum Thyroglobulin and Thyroid Hormones as Biomarkers of Asphyxia and Antemortem Stress.", The Egyptian Journal of Forensic Sciences and Applied Toxicology, vol. 4, issue 1, pp. 1-18, 2004.
Zaghlol, H. S., "Could Drug Abuse Be Related to Chest Pain in Adolescents?", The Egyptian Journal of Forensic Sciences and Applied Toxicology, vol. 3, issue 1, pp. 49-63, 2003.
Zaghlool, S. S., A. A. Abo-Seif, M. A. Rabeh, U. R. Abdelmohsen, and B. A. S. Messiha, "Gastro-Protective and Anti-Oxidant Potential of Althaea officinalis and Solanum nigrum on Pyloric Ligation/Indomethacin-Induced Ulceration in Rats", Antioxidants, vol. 8, , issue 512, pp. 1-31, 2019. 4-antioxidants_paper.pdf
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