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Y.M.Elkholy, K. A. Ali, and A. M. Farag, "Studies with pyrazol-3-carboxylic acid hydrazide: The synthesis of new pyrazolyloxadiazole and pyrazolyltriazole derivatives", Phosphorus, Sulfur, and Silicon , vol. 181, issue 9, pp. 2037-2049, 2006.
Y.Sh.Mahrous, and A.A.El-Midany, "Optimization of dye removal by activated carbon prepared from sawdust", MP Materials Tesing, vol. 58, issue 2, pp. 155-160, 2016.
Y.Z.Yassin, D.M.Blal, K.G.Mahgoub, and E.Y.Salem, "Exercise rehabilitation in homodialysis patients", Bulletin of faculty of physical therapy, vol. 12, issue 2, pp. 10, 2007. exercise_rehabilitation.doc
YA, K., H. EN, and M. HS, "Protective effect of nanocurcumin against neurotoxicity induced by doxorubicin in rat's brain. ", Neurotoxicology, vol. 85, pp. 1-9, 2021.
YA, L., S. AM, S. S, and A. AI, "Expression Signature of MicroRNA-181-a Reveals its Crucial Rule in the Pathogenesis of Paediatric Systemic Lupus Erythematosus", Clin Exp Rheumatol, 2011. Abstract

Objectives: Systemic lupus erythematosus (SLE) is an autoimmune disease manifested by self-reactive antibodies due to failure of selection in both B and T lymphocytes leading to immune intolerance accompanied by increased rate of apoptosis and deficiency in the clearance of the apoptotic cells. Micro RNAs regulate posttranscriptional gene expression and have been recently identified to regulate cellular differentiation, establishing immunological tolerance and are involved in the pathogenesis of several diseases. miR-181-a, expressed in haematopoietic cell lineage, has shown to be an important modulator of B and T cell differentiation, maturation and function. This study aims to identify the expression signature of miR-181-a in the peripheral blood of paediatric SLE and its regulatory effect on the consequent expression of its target gene PCAF.

YA, E., A. - F. M, M. B, and E. S. R, "Serum Copeptin Level as a Predictor of Outcome in Pneumonia", INDIAN PEDIATRICS, vol. 52, issue R E S E A R CH L E T T E R S, pp. 807-808, 2015. 807.pdf
ya, S., M. T. Eldesoky, A. EE, R. M, and G. AM, "post-operative physical therapy program for latissimus dorsi and teres major tendons transfer to rotator cuff in children with obstetrical brachial plexus injury", European Journal of Physical and Rehabilitation Medicine, vol. April53, issue 2, pp. 277-85, 2016. r33y2017n02a0277.pdf
YA, Z., E. A. SM, M. S. Siha, and F. SA, "Shift work and occupational accidents", Egyptian Journal of Occupational Medicine, vol. 27, issue 1, pp. 65-75, 2003.
YA, K., H. EN, M. M, and M. HS, "Antidepressant effects of curcumin-coated iron oxide nanoparticles in a rat model of depression", Eur J Pharmacol., vol. 908, pp. 174384, 2021.
Yacoub, F. M., and K. S. Ali, "Evaluation of Subfascial Breast Augmentation in Thin Patients", KASR EL AINI JOURNAL OF SURGERY, vol. 17, issue 1, pp. 99-108, 2016.
YACOUB, D. R. F. A. D. Y. M. A. G. D. E. Y., "Upper Body Contouring after Massive Weight Loss", Kasr Alaini Journal of Surgery, vol. 17, pp. MAY 2016, 2016.
Yacoub, K. A. H., The Achaemenid Empire Kings’ Religious Tolerance, , Cairo, Cairo Univercity, 2014. abstract.docx
YACOUB, D. R. F. A. D. Y. M. A. G. D. E. Y., "Expanded super thin flaps in reconstruction of face and Neck contractures", Egypt, J. Plast. Reconstr. Surg., vol. 35, issue 2, pp. JULY 307-312, 2011.
YACOUB, D. R. F. A. D. Y. M. A. G. D. E. Y., "Graduated approach for bulbous nasal tip refinement ", Kasr Alaini Journal of Surgery, vol. 12, issue 3, pp. SEPTAMBER, 2011.
YACOUB, D. R. F. A. D. Y. M. A. G. D. E. Y., "Combining techniques for the management of the droopy nasal tip", Kasr Alaini Journal of Surgery, vol. 14, issue 1, pp. January, 2013.
Yacoub, A. S., H. O. Ammar, M. Ibrahim, S. M. Mansour, and undefined, "Artificial intelligence-assisted development of insitu forming nanoparticles for arthritis therapy via intra-articular delivery", Drug Delivery , vol. 29, issue 1, pp. 1423–1436, 2022.
Yacoub, A. S., H. O. Ammar, M. Ibrahim, S. M. Mansour, and N. M. El Hoffy, "Artificial intelligence-assisted development of forming nanoparticles for arthritis therapy via intra-articular delivery.", Drug delivery, vol. 29, issue 1, pp. 1423-1436, 2022. Abstract

Intra-articular (IA) injection is grasping much interest due to the poor drug bioavailability at the targeted site of action which minimizes the effect of the orally administered moiety. Based on the integral role of non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of Rheumatoid Arthritis (RA), much effort is exerted to develop novel localized drug delivery systems to increase their bioavailability and minimize their side effects. Artificial intelligence (AI) is acquiring an increasing role in the design of experiments being an effective tool for saving both time and resources. Hence, the aim of this work was to develop, characterize and optimize targeted forming nano particles (ISNs) for IA delivery of piroxicam using Design Expert as an AI-based application where a 3 full factorial experimental design was adopted. Morphological investigation, injectability, rheological studies, Fourier Transform Infrared Radiation (FTIR) as well as biological, histopathological, and biochemical examinations were performed to evaluate the optimized-ISNs. The optimized formulation, exhibiting a nano-sized particle size with a dense core, showed significant improvement in the histopathological findings compared to both the oral solution and the placebo. Additionally, the once-a-week IA administration of the optimized-ISNs proved a significant reduction in the protein expression of both STAT-3 and RANKL and the levels of anti-CCP and MCP-1 by almost 54 and 73%, respectively, coupled with a marked decline in the content of IL-17, MMP-3, NF-κB and TNF-α as compared to the positive control. In conclusion, the use of ISNs for intra-articular injection has demonstrated their effectiveness in piroxicam delivery for RA treatment.

YACOUB, D. R. F. A. D. Y. M. A. G. D. E. Y., "Evaluation of subfascial breast augmentation in thin patients", Kasr Alaini Journal of Surgery, vol. 17, issue 1, pp. January, 2016.
Yacoub, F. M., K. S. Ali, and A. A. Nawar, "Extended Columellar Strut Graft in Tip Rhinoplasty", KASR EL AINI JOURNAL OF SURGERY, vol. 16, issue 3, pp. 89-97, 2015.
YACOUB, D. R. F. A. D. Y. M. A. G. D. E. Y., "Rhinoplasty for the thick skin", Egypt, J. Plast. Reconstr. Surg., vol. 36, issue 1, pp. January 5-9, 2012.
YACOUB, D. R. F. A. D. Y. M. A. G. D. E. Y., "Extended Columellar strut Graft in Tip Rhinoplasty ", Kasr Alaini Journal of Surgery, vol. 16, issue 3, pp. SEPTAMBER, 2015.
YACOUB, D. R. F. A. D. Y. M. A. G. D. E. Y., "Subfacial augmentation mastopexy for mild and moderate breast ptosis ", Kasr Alaini Journal of Surgery, vol. 14, issue 2, pp. MAY, 2013.