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Xiong, X., S. Zhai, Z. Yao, T. Tazawa, H. -qing Zhao, Y. Li, M. R. Meselhy, N. Nakamura, T. Akao, and M. Hattori, "和漢医薬学雑誌= Journal of traditional medicines 20 (5), 201-207, 2003-10-20", Prog. Neurobiol, vol. 56, pp. 211-235, 1998. Abstract
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Xie, M., D. Zabek, C. Bowen, M. Abdelmageed, and M. Arafa, "Wind-driven pyroelectric energy harvesting device", Smart Materials and Structures, vol. Volume 25, issue Number 12, 2016.
Nabhan, M. M., H. Abdelaziz, Y. XU, R. Elsayed, M. Santibanez-Koref, N. A. Soliman, and J. A. Sayer, "Whole-exome analysis of a child with polycystic kidney disease and ventriculomegaly", Genetics and Molecular Research, vol. 14, no. 2, pp. 3618–3624, 2015. Abstract
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Nabhan, M., H. Abdelaziz, Y. XU, R. Elsayed, M. Santibanez-Koref, N. Soliman, and J. Sayer, "A whole exome analysis of a child with polycystic kidney disease and ventriculomegaly", Genetics and Molecular Research, vol. 14, issue 2, pp. 3618-3624 , 2015.
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Xiao, S., S. Wang, D. Jiang, X. Cheng, X. Zhu, F. Lin, B. Yu, H. Dong, X. Wang, M. Munir, et al., "VP2 virus-like particles elicit protective immunity against duckling short beak and dwarfism syndrome in ducks.", Transboundary and emerging diseases, 2021. Abstract

Duckling short beak and dwarfism syndrome virus (SBDSV), an emerging goose parvovirus, has caused short beak and dwarfism syndrome (SBDS) in Chinese duck flocks since 2015. Presently, there is no commercial vaccine against SBDS. In the present study, a virus-like particle (VLP)-based candidate vaccine was developed against this disease. A baculovirus expression system was used to express the SBDSV VP2 protein in Sf9 cells. Immunofluorescence assay, sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) and Western blotting were used to confirm protein expression. Furthermore, transmission electron microscopy was used to observe the formation of VLPs. VLPs were formulated into an oil-adjuvanted maternal vaccine to evaluate humoral responses in breeding ducks via latex particle agglutination inhibition assay (LPAI) and microneutralization assay. The offspring were challenged with SBDSV to test the protective efficacy. A single dose of SBDSV was able to induce the high level of LPAI antibodies in ducks, with LPAI and neutralization peak titres of 4.9 ± 1.20 log2 and 7.1 ± 1.20 log2, respectively, at 4 weeks post-vaccination (wpv). The average LPAI titre of yolk antibodies in duck eggs receiving 2 doses (first and boost doses) of the vaccine was 5.3 ± 1.09 log2 at 4 weeks post-boost. The protective efficacy of the maternal vaccine was 87.5%-100%. These results indicate that SBDSV VLPs can be a promising vaccine candidate for controlling SBDS.

Elbendary, A., M. Valdebran, and R. Xue, "Violaceous Papules Presenting on the Foot and Lower Limb: Challenge.", The American Journal of dermatopathology, 2018 Dec 19.
Choi, A. S., R. G. Mistrick, H. Xue, M. A. Kassem, S. Kaseb, M. F. El-Refaie, C. Kabre, M. Cheng, G. R. Liu, and K. Y. Lam, vi contents, , 2016. Abstract
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Iqbal, S., A. Xin, M. U. Jan, S. Salman, A. M. ul Zaki, H. U. Rehman, M. F. Shinwari, and M. A. Abdelbaky, "V2G Strategy for Primary Frequency Control of an Industrial Microgrid Considering the Charging Station Operator", Electronics, vol. 9, issue 4, pp. 549-571, 2020.
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Ali, F. R. M., X. Xu, M. Tynan, and B. King, "Use of Price Promotions among U.S. Adults Who Use Electronic Vapor Products", American Journal of Preventive Medicine, vol. 55, issue 2, pp. 240-243, 2018.
Zhang, S., F. Hu, S. - L. Jui, A. E. Hassanien, and K. Xiao, "Unsupervised Brain MRI Tumor Segmentation with Deformation-Based Feature", the 1st International Conference on Advanced Intelligent Systems and Informatics (AISI’15) Springer, Beni Suef University, Beni Suef, Eg, Nov. 28-30, 2015.
Zhang, S., F. Hu, S. - L. Jui, A. E. Hassanien, and K. Xiao, "Unsupervised Brain MRI Tumor Segmentation with Deformation-Based Feature", The 1st International Conference on Advanced Intelligent System and Informatics (AISI2015), November 28-30, 2015, Beni Suef, Egypt: Springer International Publishing, pp. 173–181, 2016. Abstract
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Vara, M., L. T. Roling, X. Wang, A. O. Elnabawy, Z. D. Hood, M. Chi, M. Mavrikakis, and Y. Xia, "Understanding the thermal stability of palladium–platinum core–shell nanocrystals by in situ transmission electron microscopy and density functional theory", ACS nano, vol. 11, no. 5: American Chemical Society, pp. 4571–4581, 2017. Abstract
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Vara, M., L. T. Roling, X. Wang, A. O. Elnabawy, Z. D. Hood, M. Chi, M. Mavrikakis, and Y. Xia, "Understanding the thermal stability of palladium–platinum core–shell nanocrystals by in situ transmission electron microscopy and density functional theory", ACS nano, vol. 11, issue 5: American Chemical Society, pp. 4571-4581, 2017. Abstract
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Shen, P., J. Han, J. G. Zornberg, A. M. Morsy, D. Leshchinsky, B. F. Tanyu, and C. Xu, "Two and three-dimensional numerical analyses of geosynthetic-reinforced soil (GRS) piers", Geotextiles and Geomembranes, vol. 47, issue 3: Elsevier, pp. 352-368, 2019. Abstract

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Patel, C., Z. Xu, E. Shosha, J. Xing, R. Lucas, R. W. Caldwell, R. B. Caldwell, and S. P. Narayanan, "Treatment with polyamine oxidase inhibitor reduces microglial activation and limits vascular injury in ischemic retinopathy.", Biochimica et biophysica acta, vol. 1862, issue 9, pp. 1628-39, 2016 Sep. Abstract

Retinal vascular injury is a major cause of vision impairment in ischemic retinopathies. Insults such as hyperoxia, oxidative stress and inflammation contribute to this pathology. Previously, we showed that hyperoxia-induced retinal neurodegeneration is associated with increased polyamine oxidation. Here, we are studying the involvement of polyamine oxidases in hyperoxia-induced injury and death of retinal vascular endothelial cells. New-born C57BL6/J mice were exposed to hyperoxia (70% O2) from postnatal day (P) 7 to 12 and were treated with the polyamine oxidase inhibitor MDL 72527 or vehicle starting at P6. Mice were sacrificed after different durations of hyperoxia and their retinas were analyzed to determine the effects on vascular injury, microglial cell activation, and inflammatory cytokine profiling. The results of this analysis showed that MDL 72527 treatment significantly reduced hyperoxia-induced retinal vascular injury and enhanced vascular sprouting as compared with the vehicle controls. These protective effects were correlated with significant decreases in microglial activation as well as levels of inflammatory cytokines and chemokines. In order to model the effects of polyamine oxidation in causing microglial activation in vitro, studies were performed using rat brain microvascular endothelial cells treated with conditioned-medium from rat retinal microglia stimulated with hydrogen peroxide. Conditioned-medium from activated microglial cultures induced cell stress signals and cell death in microvascular endothelial cells. These studies demonstrate the involvement of polyamine oxidases in hyperoxia-induced retinal vascular injury and retinal inflammation in ischemic retinopathy, through mechanisms involving cross-talk between endothelial cells and resident retinal microglia.

Masood, A., J. Hu, A. Xin, A. R. Sayed, and G. Yang, "Transactive Energy for Aggregated Electric Vehicles to Reduce System Peak Load Considering Network Constraints", IEEE Access, vol. 8, pp. 31519-31529, 2020. Abstract
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Gilroy, K. D., A. O. Elnabawy, T. - H. Yang, L. T. Roling, J. Howe, M. Mavrikakis, and Y. Xia, "Thermal stability of metal nanocrystals: An investigation of the surface and bulk reconstructions of Pd concave icosahedra", Nano letters, vol. 17, no. 6: American Chemical Society, pp. 3655–3661, 2017. Abstract
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Gilroy, K. D., A. O. Elnabawy, T. - H. Yang, L. T. Roling, J. Howe, M. Mavrikakis, and Y. Xia, "Thermal stability of metal nanocrystals: An investigation of the surface and bulk reconstructions of Pd concave icosahedra", Nano letters, vol. 17, issue 6: American Chemical Society, pp. 3655-3661, 2017. Abstract
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Cun Hang, Fei Hu, Aboul Ella Hassanieny, and K. Xiao, "Texture-based Rotation-Invariant Histograms of Oriented Gradients", IEEE iInternational Computer Engineering Conference - ICENCO , Cairo, 30 Dec, 2015.
Hang, C., F. Hu, A. E. Hassanien, and K. Xiao, "Texture-based rotation-invariant Histograms of Oriented Gradients", Computer Engineering Conference (ICENCO), 2015 11th International: IEEE, pp. 223–228, 2015. Abstract
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Pichavaram, P., C. D. Palani, C. Patel, Z. Xu, E. shosha, A. Y. Fouda, R. B. Caldwell, and S. P. Narayanan, "Targeting Polyamine Oxidase to Prevent Excitotoxicity-Induced Retinal Neurodegeneration.", Frontiers in neuroscience, vol. 12, pp. 956, 2018. Abstract

Dysfunction of retinal neurons is a major cause of vision impairment in blinding diseases that affect children and adults worldwide. Cellular damage resulting from polyamine catabolism has been demonstrated to be a major player in many neurodegenerative conditions. We have previously shown that inhibition of polyamine oxidase (PAO) using MDL 72527 significantly reduced retinal neurodegeneration and cell death signaling pathways in hyperoxia-mediated retinopathy. In the present study, we investigated the impact of PAO inhibition in limiting retinal neurodegeneration in a model of NMDA ()-induced excitotoxicity. Adult mice (8-10 weeks old) were given intravitreal injections (20 nmoles) of NMDA or NMLA (, control). Intraperitoneal injection of MDL 72527 (40 mg/kg body weight/day) or vehicle (normal saline) was given 24 h before NMDA or NMLA treatment and continued until the animals were sacrificed (varied from 1 to 7 days). Analyses of retinal ganglion cell (RGC) layer cell survival was performed on retinal flatmounts. Retinal cryostat sections were prepared for immunostaining, TUNEL assay and retinal thickness measurements. Fresh frozen retinal samples were used for Western blotting analysis. A marked decrease in the neuronal survival in the RGC layer was observed in NMDA treated retinas compared to their NMLA treated controls, as studied by NeuN immunostaining of retinal flatmounts. Treatment with MDL 72527 significantly improved survival of NeuN positive cells in the NMDA treated retinas. Excitotoxicity induced neurodegeneration was also demonstrated by reduced levels of synaptophysin and degeneration of inner retinal neurons in NMDA treated retinas compared to controls. TUNEL labeling studies showed increased cell death in the NMDA treated retinas. However, treatment with MDL 72527 markedly reduced these changes. Analysis of signaling pathways during excitotoxic injury revealed the downregulation of pro-survival signaling molecules p-ERK and p-Akt, and the upregulation of a pro-apoptotic molecule BID, which were normalized with PAO inhibition. Our data demonstrate that inhibition of polyamine oxidase blocks NMDA-induced retinal neurodegeneration and promotes cell survival, thus offering a new therapeutic target for retinal neurodegenerative disease conditions.

Alasaada, S., R.?nC. Soriguera, M. Abu-Madib, A. E. Behairyc, M. J. Jowersa, P. D.?ez Ba?nosd, A. P.?riz a, J. F. e, Xing-, and Q. Zhuf, "A TaqMan Real-time PCR-based Assay for the Identification of Fasciola Spp", Veterinary Parasitology, 2011.
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Zhao, M., L. Xu, M. Vara, A. O. Elnabawy, K. D. Gilroy, Z. D. Hood, S. Zhou, L. Figueroa-Cosme, M. Chi, and M. Mavrikakis, "Synthesis of Ru icosahedral nanocages with a face-centered-cubic structure and evaluation of their catalytic properties", ACS Catalysis, vol. 8, issue 8: American Chemical Society, pp. 6948-6960, 2018. Abstract
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Zhao, M., L. Figueroa-Cosme, A. O. Elnabawy, M. Vara, X. Yang, L. T. Roling, M. Chi, M. Mavrikakis, and Y. Xia, "Synthesis and characterization of Ru cubic nanocages with a face-centered cubic structure by templating with Pd nanocubes", Nano letters, vol. 16, no. 8: American Chemical Society, pp. 5310–5317, 2016. Abstract
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Zhao, M., L. Figueroa-Cosme, A. O. Elnabawy, M. Vara, X. Yang, L. T. Roling, M. Chi, M. Mavrikakis, and Y. Xia, "Synthesis and characterization of Ru cubic nanocages with a face-centered cubic structure by templating with Pd nanocubes", Nano Letters, vol. 16, no. 8: American Chemical Society, pp. 5310–5317, 2016. Abstract
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