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El-Shabrawi, M. H., S. Omran, S. Wageeh, M. Isa, Sawsan Okasha, Mona Isa, N. A. Mohsen, O. Zekry, G. E-Bartan, and H. M. El-karaksy, "(99m)Technetium-macroaggregated albumin perfusion lung scan versus contrast enhanced echocardiography in the diagnosis of the hepatopulmonary syndrome in children with chronic liver disease.", European journal of gastroenterology & hepatology, vol. 22, issue 8, pp. 1006-12, 2010 Aug. Abstract

BACKGROUND AND AIMS: The hepatopulmonary syndrome (HPS) is a triad of advanced chronic liver disease (CLD), arterial hypoxemia and intrapulmonary arteriovenous shunting in the absence of a primary cardiopulmonary disease. HPS has been more frequently reported in adults than in children with no data on its prevalence in children with CLD. The aim of this study was to detect the prevalence of the HPS in a cohort of children with CLD because of chronic hepatitis B and/or C virus infection, schistosomiasis as well as inborn metabolic errors. We also aimed to evaluate the role of Technetium labeled macroaggregated albumin (Tc--MAA) perfusion lung scan versus contrast enhanced echocardiography (CEE) with intravenous injection of agitated saline in the diagnosis and quantification of intrapulmonary shunts and their relationship to important clinical and laboratory findings.

METHODS: Forty Egyptian children (22 males) were investigated. Their ages ranged from 5 to 12 years (with a mean of 9.5 years). Twenty individuals proved to have cirrhosis.

RESULTS: Blood gas determination revealed more significant arterial hypoxemia in cirrhotics than noncirrhotics both under room air and after breathing 100% oxygen for 15 mins. CEE showed comparable cardiac measurements in cirrhotic and noncirrhotic patients, and diagnosed intrapulmonary shunts in three hypoxemic cirrhotic patients; whereas Tc--MAAperfusion lung scan diagnosed shunts in seven patients (five of them cirrhotic). The presence of shunts was significantly correlated with the duration of CLD, clinical findings, presence of cirrhosis and porto-systemic collaterals. We calculated for each patient a shunt index (SI) by the formula: (activity outside thorax/activity outside plus inside thorax) 100; and an SI value of 0.278 was found to be a cutoff value for shunt detection. All patients with SI above this value had shunting associated with hypoxemia and all patients with SI below this value had no hypoxemia (specificity 100%).

CONCLUSION: Arterial hypoxemia and intrapulmonary shunts were diagnosed in 17.5% of this cohort of children with cirrhotic or noncirrhotic CLD representing the classic HPS. Tc--MAA perfusion lung scan was more sensitive than CEE in detection of intrapulmonary shunts. SI cutoff value of 0.278 was found to be highly specific for shunt detection and we recommend its validation in further studies.

Thabit, S., H. Handoussa, M. Roxo, B. C. de Azevedo, N. S E El Sayed, and M. Wink, "(L.) Schott Fruits Increase Stress Resistance and Exert Antioxidant Properties in and Mouse Models.", Molecules (Basel, Switzerland), vol. 24, issue 14, 2019. Abstractpaper_iii.pdf

(L.) Schott is a popular Asian tree widely used in traditional medicine. The current study explored the potential stress resistance and antioxidant activities of its fruits. Phytochemical profiling of the hydroalcoholic fruit extract was done via high performance liquid chromatography-photodiode array-electrospray ionization-mass/mass (HPLC-PDA-ESI-MS/MS). Twenty four phenolic constituents were tentatively identified in the extract. The () nematode model in addition to trimethyltin (TMT)-induced neurotoxicity mouse model were used for in vivo evaluation of its antioxidant properties. The ability of the extract to enhance stress resistance was manifested through increasing survival rate by 44.7% and decreasing basal reactive oxygen species (ROS) levels by 72.3% in . In addition, the extract increased the levels of the stress response enzyme superoxide dismutase-3 (Sod-3) by 55.5% and decreased the expression of heat shock protein-16.2 (Hsp-16.2) in nematodes, which had been challenged by juglone, by 21%. Using a mouse model, the extract significantly decreased the expression of the oxidative stress marker malondialdehyde (MDA). Furthermore, an elevation in the levels of the antioxidant marker glutathione (GSH), SOD and heme oxygenase-1 (HO-1) enzymes were observed. Our findings imply that has the potential to be used in future studies focusing on diseases associated with oxidative stress.

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Kassem, H., F. Alshiekh, A. Wafaie, S. Abdelfattah, H. Farghaly, and L. Afifi, "- Presurgical evaluation of refractory temporal lobe epilepsy: Comparison of MR imaging, PET and ictal SPECT in localization of the epileptogenic substrate. ", The Egyptian Journal of Radiology and Nuclear Medicine, vol. 44, issue 3, pp. 641-649, 2013.
E., H., M. H., O. W., and E. A., "- The Value of Quantitative Analysis in Evaluation of the Prognostic Role of Interim FDG-PET/CT in Pediatric Hodgkin’s Lymphoma in Egypt", Egyptian J. Nucl. Med., vol. 11, issue 1, pp. 11-25, 2015.
Bun, S. - S., D. G. Laţcu, A. M. Wedn, and N. Saoudi, - Double devices: Dysfunction or not?, , 2018. douple_device_dysfunction_or_not.pdf
Wardakhan, W. W., S. M. Sherif, R. M. Mohareb, and A. S. Abouzied, "- The reaction of cyanoacetylhdrazine with furan-2-aldehyde: novel synthesis of thiophene, azole, azine and coumarin derivatives and their antitumor evaluation", International J. of Organic Chem. , vol. 2, pp. 321-331, 2012.
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Farag, M., ludger wessjohan, and M. A. Fattah, ". Profiling the chemical content of Ficus lyrata extracts via UPLC-PDA-qTOF-MS and chemometrics", Natural Product Research , vol. 28, issue 19, pp. 1549-56., 2014. 6-farag_et_al._natural_product_research_2014.pdf
Farag, M. A.:, A. Porzel, J. Schmidt, and L. A. Wessjohann, "., Comparative MS and NMR metabolomics: a case study of hops (Humulus lupulus)", Metabolomics, vol. 8, pp. 492-507, 2012. farag_et_al._2012_metabolomics.pdf
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Koschke, R., A. Walenstein, and E. Merlo, "06301 Abstracts Collection–Duplication, Redundancy, and Similarity in Software", Dagstuhl Seminar Proceedings: Schloss Dagstuhl-Leibniz-Zentrum für Informatik, 2007. Abstract
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l Burnett, M. N., R. Boothe, E. Clark, M. Gisin, H. M. Hassaneen, R. M. Pagni, G. Persy, R. J. Smith, and J. Wirz, "1,4-Perinaphthadiyl. Singlet- and Triplet-State Reactivity of a Conjugated Hydrocarbon Biradical.", J. Am. Chem. Soc. , vol. 110, pp. 2527-2538, 1988.
MarwaM.Eid, I. S. Waked, and A. F. Atalla, "1- Low Level Laser Therapy for the treatment of Trigeminal Neuralgia after Oral surgeries: Two Different Applications ", March2015, International J. of Health& Rehabilitation science Vol.,4,1: 10-18, vol. 4, issue 1, pp. 10-18, 2015. 20-1430671183.pdf
Pennell, D. J., J. B. Porter, A. Piga, Y. Lai, A. El-Beshlawy, K. M. Belhoul, M. Elalfy, A. Yesilipek, Y. Kilinç, T. Lawniczek, et al., "A 1-year randomized controlled trial of deferasirox vs deferoxamine for myocardial iron removal in β-thalassemia major (CORDELIA).", Blood, vol. 123, issue 10, pp. 1447-54, 2014 Mar 6. Abstract

Randomized comparison data on the efficacy and safety of deferasirox for myocardial iron removal in transfusion dependent patients are lacking. CORDELIA was a prospective, randomized comparison of deferasirox (target dose 40 mg/kg per day) vs subcutaneous deferoxamine (50-60 mg/kg per day for 5-7 days/week) for myocardial iron removal in 197 β-thalassemia major patients with myocardial siderosis (T2* 6-20 milliseconds) and no signs of cardiac dysfunction (mean age, 19.8 years). Primary objective was to demonstrate noninferiority of deferasirox for myocardial iron removal, assessed by changes in myocardial T2* after 1 year using a per-protocol analysis. Geometric mean (Gmean) myocardial T2* improved with deferasirox from 11.2 milliseconds at baseline to 12.6 milliseconds at 1 year (Gmeans ratio, 1.12) and with deferoxamine (11.6 milliseconds to 12.3 milliseconds; Gmeans ratio, 1.07). The between-arm Gmeans ratio was 1.056 (95% confidence interval [CI], 0.998, 1.133). The lower 95% CI boundary was greater than the prespecified margin of 0.9, establishing noninferiority of deferasirox vs deferoxamine (P = .057 for superiority of deferasirox). Left ventricular ejection fraction remained stable in both arms. Frequency of drug-related adverse events was comparable between deferasirox (35.4%) and deferoxamine (30.8%). CORDELIA demonstrated the noninferiority of deferasirox compared with deferoxamine for myocardial iron removal. This trial is registered at www.clinicaltrials.gov as #NCT00600938.

Writer, E. Y., and L. Y. Translator, A 1/4 Gram, , Cairo, Al Dar Al Masriah Al Lubnaniah, 2009.
Basha, T., E. - S. Ibrahim, M. L. Shehata, R. G. Weiss, and N. F. Basha, "1141 Can every other heart-beat acquisition be better for the same breath-hold interval in MR tagging sequences?", Journal of Cardiovascular Magnetic Resonance, vol. 10, issue 1: BioMed Central, pp. 1, 2008. Abstract
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Basha, T., E. - S. Ibrahim, M. L. Shehata, R. G. Weiss, and N. F. Basha, "1141 Can every other heart-beat acquisition be better for the same breath-hold interval in MR tagging sequences?", Journal of Cardiovascular Magnetic Resonance, vol. 10, no. 1: BioMed Central, pp. A266, 2008. Abstract
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Christine, B., S. K. Wilson, R. Shamloul, and A. J. Bella, "1265 SIMULTANEOUS PLACEMENT OF AN INFLATABLE PENILE PROSTHESIS AND ADVANCE MALE SLING FOR ERECTILE DYSFUNCTION AND INCONTINENCE: ROBUST EFFICACY AND SAFETY DATA AT 2 YEAR FOLLOW-UP", The Journal of Urology, vol. 183, no. 4: Elsevier, pp. e490, 2010. Abstract
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Christine, B., S. K. Wilson, R. Shamloul, and A. J. Bella, "1265 SIMULTANEOUS PLACEMENT OF AN INFLATABLE PENILE PROSTHESIS AND ADVANCE MALE SLING FOR ERECTILE DYSFUNCTION AND INCONTINENCE: ROBUST EFFICACY AND SAFETY DATA AT 2 YEAR FOLLOW-UP", The Journal of Urology, vol. 183, no. 4: Elsevier, pp. e490, 2010. Abstract
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Khedr, R., M. A. Waged, M. Fathy, and W. Zekri, "1534. Prevalence and Outcome of Neutropenic Enterocolitis Among Pediatric Acute Myeloid Leukemia Patients: A Developing Country Experience", Open Forum Infectious Diseases, vol. 5, issue Suppl 1: Oxford University Press, pp. S476, 2018. Abstract
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Khedr, R., M. A. Waged, M. Fathy, and W. Zekri, "1534. Prevalence and Outcome of Neutropenic Enterocolitis Among Pediatric Acute Myeloid Leukemia Patients: A Developing Country Experience", Open Forum Infectious Diseases, vol. 5, issue Suppl 1: Oxford University Press, pp. S476, 2018. Abstract
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Bella, A., R. Wang, R. Shamloul, C. Zappavigna, M. Ahmed, and H. Sadeghi-Nejad, "1859 3-PIECE INFLATABLE PENILE PROSTHESIS INSERTION POST T-SHUNT FOR PRIAPISM WITH DILATION/CORPORAL SNAKE MANEUVER AND COMPARISON TO POST AL-GHORAB SHUNT IPP OUTCOMES", The Journal of Urology, vol. 187, no. 4: Elsevier, pp. e751–e752, 2012. Abstract
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S.A., A., Ghoneim D.F., B. Y.A., and A. W., "193 nm ArF Excimer Laser and the Potential Risk for Cataract Formation", Journal of Applied Sciences Research, (7): , 2010, vol. (7), issue 6, pp. 796-805, 2010.
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Walaa H. Mahmoud, G. G. Mohamed, and Maher M.I. El-Dessouky, "2- Synthesis, Characterization and in vitro Biological Activity of Mixed Transition Metal Complexes of Lornoxicam with 1,10-phenanthroline.", Int. J. Electrochem. Sci, vol. 9, pp. 1415-1438, 2014. wgm-ijecs.pdf
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