Publications

Export 1121 results:
Sort by: Author [ Title  (Desc)] Type Year
A B C D E F G H I J K L M N O P Q R S T U [V] W X Y Z   [Show ALL]
Safaa, H. M., M. P. Serrano, D. G. Valencia, X. Arbe, E. Jiménez-Moreno, R. Lázafo, G. G. Mateos, 霍艳军, and 雷蕾, "日粮中蛋氨酸, 亚油酸和脂肪添加水平对伊莎褐蛋鸡产蛋后期生产性能和蛋品质的影响", 饲料与畜牧: 新饲料, no. 9, pp. 58–58, 2008. Abstract
n/a
Safaa, H. M., M. P. Serrano, D. G. Valencia, X. Arbe, E. Jiménez-Moreno, R. Lázafo, G. G. Mateos, 霍艳军, and 雷蕾, "日粮中蛋氨酸, 亚油酸和脂肪添加水平对伊莎褐蛋鸡产蛋后期生产性能和蛋品质的影响", 饲料与畜牧: 新饲料, no. 9, pp. 58–58, 2008. Abstract
n/a
{
El-Boghdadi, H. M., R. Vaidyanathan, J. L. Trahan, and S. Rai, "{On the Communication Capability of the Self-Reconfigurable Gate Array Architecture}", International Parallel and Distributed Processing Symposium/International Parallel Processing Symposium, 2002. Abstract
n/a
El-Boghdadi, H. M., R. Vaidyanathan, J. L. Trahan, and S. Rai, "{On Designing Implementable Algorithms for the Linear Reconfigurable Mesh}", Parallel and Distributed Processing Techniques and Applications, pp. 241–246, 2003. Abstract
n/a
Mehaisen, G. M. K., J. S. Vicente, and R. Lavara, "{In Vivo Embryo Recovery Rate by Laparoscopic Technique from Rabbit Does Selected for Growth Rate}", Reprod Dom Anim, vol. 39, pp. 347–351, 2004. Abstract2004_rda.pdf

Rabbit does from R line selected for growth rate present a low reproductive performance and this study aimed to evaluate both the recovery efficacy and viability of recovered embryos after vitrification and the reproductive performance of donor does subjected to in vivo recovery. Does were divided into three groups: 28 does without in vivo recovery (control), 25 does in which in vivo recovery was started in the nulliparous state (group 1) and 30 does with at least one litter before in vivo recovery (group 2). Does were superovulated with a single subcutaneous injection of 50 IU of equine chorionic gonado- tropin (eCG) per female, and were then artificially inseminated 60 h later and immediately administered an intravenous dose of 75 IU of human chorionic gonadotropin (hCG) per female. Does from group 1 and 2 were recovered in vivo 76–80 h post- insemination by repeated laparoscopies at one to four times and permitted one or two parturitions between recoveries [in vivo (IV) recovery]. At the end of the experiment, about 16 does of all groups were recovered post-mortem (PM recovery). All normal embryos were vitrified, devitrified and then cultiva- ted in vitro to evaluate the viability after thawing. A significant increase in the ovulation rate was found in does recovered PM than in those recovered IV in the nulliparous state. However, no significant differences were observed in the recovery rate, the donor rate, the number of normal embryos recovered with at least one normal embryo per doe and the viability after thawing between the PM and IV groups. A significant decrease in the fertility rate, total born, live born and weaned kids was found for does from group 1 in comparison with does from group 2. Results support the use of repeated laparoscopy to increase the number of recovered embryos per donor doe especially in suchRline does, if they are permitted to produce at least one litter before the beginning of in vivo recovery.

Mehaisen, G. M. K., M. \'ıa P. Viudes-de-Castro, J. S. Vicente, and R. Lavara, "{In vitro and in vivo viability of vitrified and non-vitrified embryos derived from eCG and FSH treatment in rabbit does.}", Theriogenology, vol. 65, no. 7, pp. 1279–91, 2006. Abstract2006_theriogenology.pdfWebsite

This study aimed to evaluate the in vitro and in vivo viability of vitrified and non-vitrified embryos derived from eCG and FSH treatments in rabbit does. Ninety-six nulliparous does were randomly subjected to consecutive superovulation treatments with eCG (20 IU/kg body weight intramuscularly (i.m.), eCG group), FSH (3 x 0.6 mg/doe at 24 h intervals i.m., FSH group), or without superovulation treatment (control group). Does were artificially inseminated 3 days later and ovulation was induced immediately by hCG (75 IU/doe intravenous). Seven experimental groups were differentiated: first FSH and eCG treatment, second FSH and eCG treatment, eCG-interchanged group (does with previous FSH treatment), FSH-interchanged group (does with previous eCG treatments) and control group. Embryos were collected in vivo by laparoscopy 76-80 h post-insemination in the first and second recovery cycles and post mortem in the third recovery cycles. The ovulation rate was significantly higher in does treated with the first-FSH than in those treated with eCG or in control does (25.2+/-2.0 versus 19.2+/-1.4 to 11.0+/-1.5, and 12.2+/-1.2, first-FSH, first-eCG to second-eCG and control groups, respectively, P < 0.05). Significant differences were observed in the total recovery influenced by ovulation rate in each group (20.3+/-2.2 to 9.4+/-1.2, first-FSH to control groups). Embryo donor rate (donor with at least one normal embryo) was similar among groups with an overall of 75.1%. The number of normal embryos recovered per doe with at least one normal embryo increased significantly in relation to ovulation rate (17.7+/-2.2 to 8.41+/-3, first-FSH and control groups). The vitrification of embryos negatively affected their in vitro development to hatched blastocyst in all groups (88.1% versus 48%, P > 0.05). However, after embryo transfer, this negative effect was only observed in superovulated vitrified embryos (16.8 and 12.8% versus 39.4% total born rate from eCG, FSH and control vitrified groups, P < 0.05). Results indicated that the primary treatments with eCG or FSH increased the number of normal embryos recovered per donor doe, but these embryos are more sensitive to vitrification protocols.

El-Boghdadi, H. M., R. Vaidyanathan, J. L. Trahan, and S. Rai, "{Implementing Prefix Sums and Multiple Addition Algorithms for the Reconfigurable Mesh on the Reconfigurable Tree Array}", Parallel and Distributed Processing Techniques and Applications, pp. 1068–1074, 2002. Abstract

n/a

Vagenas, E. C., A. F. Ali, and H. Alshal, {GUP and the no-cloning theorem}, , 2018. Abstract
n/a
Mehaisen, G. M. K., J. S. Vicente, R. Lavara, and M. P. Viudes-de-Castro, "{Effect of eCG dose and ovulation induction treatments on embryo recovery and in vitro development post-vitrification in two selected lines of rabbit does}", Animal Reproduction Science, vol. 90, no. 1-2, pp. 175–184, 2005. Abstract2005_ars.pdfWebsite

The aim of this work was to evaluate the effect of different doses of eCG administered subcu- taneously (0, 50 and 200 IU) and the hormonal induction of ovulation (GnRH or hCG) on embryo recovery and in vitro development of embryos post-vitrification in two selected lines of rabbit does. The two selected lines were line V (selected for the litter size at weaning) and line R (selected for growth rate). Administration of 200 IU of eCG significantly increased ovulation rate (19.2±1.2 ver- sus 15.5±1.1 and 12.2±1.3, and the number of haemorrhagic follicles (13.8±1.6 versus 3.8±1.4 and 3.8±1.7), but significantly decreased recovery rate (28.8±6.3 versus 47.7±5.7 and 48.7±6.7, 200 IU versus 50 IU and 0 IU eCG, respectively), the number of normal embryos recovered per doe with at least one embryo (5.8±0.9 versus 8.2±0.9, 200 IU versus 50 IU eCG doses) and the in vitro development of embryos post-vitrification (51.9% versus 66.1%, 200 IU versus 50 IU eCG doses, re- spectively). Inducing ovulation with hCG significantly increased ovulation rate when compared with GnRH (17.3±0.8 versus 13.8±1.4), but no significant differences in embryo recovery and embryo development post-vitrification were observed between the two treatments. No significant differences were observed between the two selected lines in ovulation and recovery rates, the number of haem- orrhagic follicles and the number of recovered embryos per doe. However, the post-vitrification in vitro rate of development was 59.7% for line R and 51.9% for line V (p<0.05). It was concluded that the use of 50 IU of eCG subcutaneous with hCG or GnRH prior to embryo cryopreservation programmes in rabbits achieves the best results for embryo recovery, with the best development of recovered embryos post-vitrification.

Safaa, H. M., R. Lavara, D. A. A. Elsayed, G. M. K. Mehaisen, and J. S. Vicente, "{EFFECT OF DIFFERENT FREEZING EXTENDERS ON SEMEN QUALITY , FERTILITY AND PROLIFICACY IN TWO SELECTED LINES}", 10 th World Rabbit Congress, pp. 325–329, 2012. Abstract2012_r11_safaa.pdf

The aim of this study was to evaluate the cryoprotective effect of different freezing extenders against
cryopreservation injuries on rabbit sperms of 2 lines selected for hyper-prolificacy (H) and longevity (L).
Ejaculates were collected and pooled from ten sexually mature rabbit bucks per each line. A total number
of 196 pooled semen ejaculates per line were used to evaluate post-thawing semen by 252 artificial
inseminations using White New Zealand rabbit does. Semen was equally divided into 3 volumes and
diluted (1:1) with different TRIS-citric acid based extenders (A, B and C). In extender A, 3 M dimethyl
sulfoxide and 0.1 M sucrose were added as cryoprotectants. For extender B, the sucrose in extender A was
replaced by 20% egg-yolk, and for extender C, the TRIS-based extender was supplemented with 2 M
acetamide and 20% egg-yolk. No interaction effect was detected between rabbit line and semen extender
on studied traits. Moreover, no significant differences were detected between H- and L-lines for all traits
except for prolificacy that was higher in L- line (6.04 vs. 4.37 young born at birth, respectively). However,
freezing semen with extender A and B showed better post-thawing semen quality characteristics, fertility
and prolificacy than frozen semen with extender C. It could be concluded that extenders A and B are
preferable for freezing semen of H- and L-rabbit lines than extender C to obtain higher fertility and
prolificacy. A moderate and interesting relationship was found between acrosomal integrity of frozen
semen and fertility rate. (r=0.17; P=0.04).

\
Akizu, N., V. Cantagrel, J. Schroth, N. Cai, K. Vaux, D. McCloskey, R.  K. Naviaux, J. Van Vleet, A.  G. Fenstermaker, J.  L. Silhavy, et al., "\{AMPD2\} Regulates \{GTP\} Synthesis and Is Mutated in a Potentially Treatable Neurodegenerative Brainstem Disorder", Cell, vol. 154, no. 3, pp. 505 - 517, 2013. AbstractWebsite
n/a
[
Schmidbauer, J. M., L. Werner, D. J. Apple, S. K. Pandey, A. M. Izak, R. H. Trivedi, T. A. Macky, G. U. Auffarth, Q. Peng, S. N. Arthur, et al., "[Postoperative opacification of posterior chamber intraocular lenses - a review].", Klinische Monatsblatter fur Augenheilkunde, vol. 218, issue 9, pp. 586-94, 2001 Sep. Abstract

Postoperative opacification of intraocular lenses (IOLs) is a very unpleasant complication for the ophthalmic surgeon and the patient. We report on our experiences with opacification of different foldable IOL designs and rigid poly (methyl methacrylate) (PMMA) posterior chamber lenses.1. Snowflake degeneration of PMMA IOLs: This condition is an unanticipated and surprising late postoperative finding 8 to 15 years after implantation. In our opinion, this complication is probably not related to the PMMA biomaterial itself, but rather it appears to represent a manufacturing problem that has affected a selected, albeit large number of lenses manufactured in the 1980s-mid 1990s.2. Degeneration of UV absorber material and calcium deposits within the optic of hydrophilic IOLs: Two years postoperatively degenerations of UV absorber material and calcium deposits within the optic of single piece hydrophilic acrylic lenses SC60B-OUV manufactured by MDR (Medical developmental research Inc. Clearwater FL, USA) can occur. Although the precise mechanism is not fully known, it was assumed that these opacifications are due to premature aging of the UV blocking agent incorporated in the lens biomaterial and calcification.3. Calcification on the surface of the Bausch & Lomb Hydroviewtrade mark IOLs: Twelve to 15 months postoperatively granular surface calcifications in Hydroviewtrade mark IOLs occured. The mechanism is not fully understood. According to Bausch and Lomb studies, part of the components of the packaging contained silicone, which may have come off the packaging onto the lens optic, where it then appears to be a catalyst for calcium precipitation. The manufacturer has correlated a change in packaging with the appearance of the opacification. The manufacturer now believes that this problem has been solved. However, final verification will require a careful 1 - 2 years clinical study.4. Glistenings in the hydrophobic acrylic AcrySoftrade mark IOLs: The time frame of glistenings in the AcrySoftrade mark IOLs is highly variable. It has been suggested that the occurrence of glistenings may be related to variations in the temperature of the lens just prior to and or during insertion into the eye. Formation of vacuoles may occur within the submersed acrylic polymer when there is a transient increase and then decrease in temperature during the surgical procedure. "Glistenings" may then subsequently form by ingress of anterior chamber fluid. Contrast sensitivity can been decreased in some patients, but clinically significant decrease of visual acuity has been rare.

González Mateos, G., M. P. Serrano, D. G. Valencia, R. Lázaro, H. M. Safaa, and X. Arbe, "[Effect of methionine level, linoleic acid and added fat to diet on performance and egg quality in Lohmann Brown hens during the last stages of production cycle]", ITEA (Información Técnica Económica Agraria). Producción Animal (España), 2007. Abstract
n/a
W
Vannozzi, A., I. Hmmam, J. Holl, J. Bogs, I. Dry, G. Barcaccia, and M. Lucchin, "WRKY transcription factors and regulation of the stilbene biosynthetic pathway in grapevine: new insights and perspectives", X International Symposium on Grapevine Physiology and Biotechnology 1188, pp. 1-8, 2016. Abstract
n/a
Vannozzi, A., I. Hmmam, J. Holl, J. Bogs, I. Dry, G. Barcaccia, and M. Lucchin, "WRKY transcription factors and regulation of the stilbene biosynthetic pathway in grapevine: new insights and perspectives", Acta Hort, vol. 1188, pp. 1-8, 2017.
Umar, M., A. G. Khan, Z. Abbas, S. Arora, N. Asifabbas, A. Elewaut, G. Esmat, G. Foster, M. Fried, K. - L. Goh, et al., "World Gastroenterology Organisation global guidelines: diagnosis, management and prevention of hepatitis C April 2013.", Journal of clinical gastroenterology, vol. 48, issue 3, pp. 204-17, 2014 Mar. Abstract
n/a
Ahmed, A. A., A. A. Mohamed, I. A. Guled, H. M. Elamin, A. H. Abou-Zeid, J. Loko Roka, R. Van den Bergh, S. Au, E. De Plecker, R. Zachariah, et al., Womens/Reproductive Health:[32], , Submitted. Abstract
n/a
Abdel-Aziz, H., W. Wadie, D. M. Abdallah, B. Vinson, O. Kelber, D. Weiser, and M. T. Khayyal, "Wirkung von STW 5 in einem experimentellen Kolitis-Modell", Zeitschrift für Gastroenterologie, vol. 46, no. 09, pp. P362, 2008. Abstract
n/a
Abdel-Aziz, H., W. Wadie, D. M. Abdallah, B. Vinson, O. Kelber, D. Weiser, and M. T. Khayyal, "Wirkung von STW 5 in einem experimentellen Kolitis-Modell", Zeitschrift für Gastroenterologie, vol. 46, issue 09, pp. P362, Submitted. Abstract
n/a
van der Ven, A. T., D. M. Connaughton, H. Ityel, N. Mann, M. Nakayama, J. Chen, A. Vivante, D. - Y. Hwang, J. Schulz, D. A. Braun, et al., "Whole-Exome Sequencing Identifies Causative Mutations in Families with Congenital Anomalies of the Kidney and Urinary Tract.", Journal of the American Society of Nephrology : JASN, vol. 29, issue 9, pp. 2348-2361, 2018 Sep. Abstract

BACKGROUND: Congenital anomalies of the kidney and urinary tract (CAKUT) are the most prevalent cause of kidney disease in the first three decades of life. Previous gene panel studies showed monogenic causation in up to 12% of patients with CAKUT.

METHODS: We applied whole-exome sequencing to analyze the genotypes of individuals from 232 families with CAKUT, evaluating for mutations in single genes known to cause human CAKUT and genes known to cause CAKUT in mice. In consanguineous or multiplex families, we additionally performed a search for novel monogenic causes of CAKUT.

RESULTS: In 29 families (13%), we detected a causative mutation in a known gene for isolated or syndromic CAKUT that sufficiently explained the patient's CAKUT phenotype. In three families (1%), we detected a mutation in a gene reported to cause a phenocopy of CAKUT. In 15 of 155 families with isolated CAKUT, we detected deleterious mutations in syndromic CAKUT genes. Our additional search for novel monogenic causes of CAKUT in consanguineous and multiplex families revealed a potential single, novel monogenic CAKUT gene in 19 of 232 families (8%).

CONCLUSIONS: We identified monogenic mutations in a known human CAKUT gene or CAKUT phenocopy gene as the cause of disease in 14% of the CAKUT families in this study. Whole-exome sequencing provides an etiologic diagnosis in a high fraction of patients with CAKUT and will provide a new basis for the mechanistic understanding of CAKUT.

Warejko, J. K., W. Tan, A. Daga, D. Schapiro, J. A. Lawson, S. Shril, S. Lovric, S. Ashraf, J. Rao, T. Hermle, et al., "Whole Exome Sequencing of Patients with Steroid-Resistant Nephrotic Syndrome.", Clinical journal of the American Society of Nephrology : CJASN, vol. 13, issue 1, pp. 53-62, 2018 Jan 06. Abstract

BACKGROUND AND OBJECTIVES: Steroid-resistant nephrotic syndrome overwhelmingly progresses to ESRD. More than 30 monogenic genes have been identified to cause steroid-resistant nephrotic syndrome. We previously detected causative mutations using targeted panel sequencing in 30% of patients with steroid-resistant nephrotic syndrome. Panel sequencing has a number of limitations when compared with whole exome sequencing. We employed whole exome sequencing to detect monogenic causes of steroid-resistant nephrotic syndrome in an international cohort of 300 families.

DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Three hundred thirty-five individuals with steroid-resistant nephrotic syndrome from 300 families were recruited from April of 1998 to June of 2016. Age of onset was restricted to <25 years of age. Exome data were evaluated for 33 known monogenic steroid-resistant nephrotic syndrome genes.

RESULTS: In 74 of 300 families (25%), we identified a causative mutation in one of 20 genes known to cause steroid-resistant nephrotic syndrome. In 11 families (3.7%), we detected a mutation in a gene that causes a phenocopy of steroid-resistant nephrotic syndrome. This is consistent with our previously published identification of mutations using a panel approach. We detected a causative mutation in a known steroid-resistant nephrotic syndrome gene in 38% of consanguineous families and in 13% of nonconsanguineous families, and 48% of children with congenital nephrotic syndrome. A total of 68 different mutations were detected in 20 of 33 steroid-resistant nephrotic syndrome genes. Fifteen of these mutations were novel.,,, andwere the most common genes in which we detected a mutation. In another 28% of families, we detected mutations in one or more candidate genes for steroid-resistant nephrotic syndrome.

CONCLUSIONS: Whole exome sequencing is a sensitive approach toward diagnosis of monogenic causes of steroid-resistant nephrotic syndrome. A molecular genetic diagnosis of steroid-resistant nephrotic syndrome may have important consequences for the management of treatment and kidney transplantation in steroid-resistant nephrotic syndrome.

Daga, A., A. J. Majmundar, D. A. Braun, H. Y. Gee, J. A. Lawson, S. Shril, T. Jobst-Schwan, A. Vivante, D. Schapiro, W. Tan, et al., "Whole exome sequencing frequently detects a monogenic cause in early onset nephrolithiasis and nephrocalcinosis.", Kidney international, vol. 93, issue 1, pp. 204-213, 2018 Jan. Abstract

The incidence of nephrolithiasis continues to rise. Previously, we showed that a monogenic cause could be detected in 11.4% of individuals with adult-onset nephrolithiasis or nephrocalcinosis and in 16.7-20.8% of individuals with onset before 18 years of age, using gene panel sequencing of 30 genes known to cause nephrolithiasis/nephrocalcinosis. To overcome the limitations of panel sequencing, we utilized whole exome sequencing in 51 families, who presented before age 25 years with at least one renal stone or with a renal ultrasound finding of nephrocalcinosis to identify the underlying molecular genetic cause of disease. In 15 of 51 families, we detected a monogenic causative mutation by whole exome sequencing. A mutation in seven recessive genes (AGXT, ATP6V1B1, CLDN16, CLDN19, GRHPR, SLC3A1, SLC12A1), in one dominant gene (SLC9A3R1), and in one gene (SLC34A1) with both recessive and dominant inheritance was detected. Seven of the 19 different mutations were not previously described as disease-causing. In one family, a causative mutation in one of 117 genes that may represent phenocopies of nephrolithiasis-causing genes was detected. In nine of 15 families, the genetic diagnosis may have specific implications for stone management and prevention. Several factors that correlated with the higher detection rate in our cohort were younger age at onset of nephrolithiasis/nephrocalcinosis, presence of multiple affected members in a family, and presence of consanguinity. Thus, we established whole exome sequencing as an efficient approach toward a molecular genetic diagnosis in individuals with nephrolithiasis/nephrocalcinosis who manifest before age 25 years.

Carson, M., J. K. Keppler, G. Brackman, D. Dawood, M. Vandrovcova, K. Fawzy El-Sayed, T. Coenye, K. Schwarz, S. A. Clarke, and A. G. Skirtach, "Whey protein complexes with green tea polyphenols: antimicrobial, osteoblast-stimulatory, and antioxidant activities", Cells Tissues Organs, vol. 206, issue 1-2: Karger Publishers, pp. 106-118, 2018. Abstract
n/a
Carson, M., J. K. Keppler, G. Brackman, D. Dawood, M. Vandrovcova, K. Fawzy El-Sayed, T. Coenye, K. Schwarz, S. A. Clarke, and A. G. Skirtach, "Whey protein complexes with green tea polyphenols: antimicrobial, osteoblast-stimulatory, and antioxidant activities", Cells Tissues Organs, vol. 206, issue 1-2: Karger Publishers, pp. 106-118, 2018. Abstract
n/a
Elbendary, A., M. Valdebran, A. A. Gad, and D. M. Elston, "When to suspect tinea; a histopathologic study of 103 cases of PAS-positive tinea.", Journal of cutaneous pathology, vol. 43, issue 10, pp. 852-7, 2016 Oct. Abstract

BACKGROUND: The histopathologic features of tinea vary widely and its diagnosis could be easily missed if the index of suspicion is not high. We aimed in this study to detect histopathologic features that could be a clue for diagnosis

METHODS: We retrospectively reviewed 103 cases of tinea, confirmed by Periodic acid-Schiff (PAS) staining. For each case, gender, biopsy site, and pre-biopsy suspicion were recorded. The presence or absence of 17 microscopic features was noted.

RESULTS: Concordance between pre-biopsy and histopathologic diagnosis was noted in 57.28% of cases, suggesting that the diagnosis is often not suspected clinically. Among the histopathologic features studied, a compact stratum corneum (either uniform or forming a layer beneath a basket weave stratum corneum), parakeratosis, mild spongiosis and neutrophils in the stratum corneum and within the blood vessels were the most frequent features noted.

CONCLUSION: This study suggests histopathologic clues that should prompt the pathologist to order a PAS stain, especially when diagnosis is not suspected clinically.

Tourism