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Fathy, H., undefined, I. Ali, and R. Tabashy, "Additive value of F-18FDG PET/CT in pancreatic mass evalution", Egyptian journal of nuclear medicine, vol. 13, issue 1, pp. 23-28, 2016.
Fathy, H., undefined, I. Ali, and R. Tabashy, "Additive value of F-18FDG PET/CT in pancreatic mass evalution", Egyptian journal of nuclear medicine, vol. 13, issue 1, pp. 23-28, 2016.
AH, C., S. M, P. - J. A, A. AS, P. B. Larson D, G. T, S. A, and L. A, "Addressing the Challenge of Financial Sustainability in Biobanking, Biopreserv Biobank.", Biopreservation and Biobanking., vol. 13, issue 6, pp. 387-95, 2015. ahmedsamir_1.pdf
Mylvaganam, S., E. J. Conroy, P. R. Williamson, N. L. P. Barnes, R. I. Cutress, M. D. Gardiner, A. Jain, J. M. Skillman, S. Thrush, L. J. Whisker, et al., "Adherence to best practice consensus guidelines for implant-based breast reconstruction: Results from the iBRA national practice questionnaire survey.", European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, vol. 44, issue 5, pp. 708-716, 2018 05. Abstract

INTRODUCTION: The 2008 National Mastectomy and Breast Reconstruction Audit demonstrated marked variation in the practice and outcomes of breast reconstruction in the UK. To standardise practice and improve outcomes for patients, the British professional associations developed best-practice guidelines with specific guidance for newer mesh-assisted implant-based techniques. We explored the degree of uptake of best-practice guidelines within units performing implant-based reconstruction (IBBR) as the first phase of the implant Breast Reconstruction Evaluation (iBRA) study.

METHODS: A questionnaire developed by the iBRA Steering Group was completed by trainee and consultant leads at breast and plastic surgical units across the UK. Simple summary statistics were calculated for each survey item to assess compliance with current best-practice guidelines.

RESULTS: 81 units from 79 NHS Trusts completed the questionnaire. Marked variation was observed in adherence to guidelines, especially those relating to clinical governance and infection prevention strategies. Less than half (n = 28, 47%) of units obtained local clinical governance board approval prior to offering new mesh-based techniques and prospective audit of the clinical, cosmetic and patient-reported outcomes of surgery was infrequent. Most units screened for methicillin-resistant staphylococcus aureus prior to surgery but fewer than 1 in 3 screened for methicillin-sensitive strains. Laminar-flow theatres (recommended for IBBR) were not widely-available with less than 1 in 5 units having regular access. Peri-operative antibiotics were widely-used, but the type and duration were highly-variable.

CONCLUSIONS: The iBRA national practice questionnaire has demonstrated variation in reported practice and adherence to IBBR guidelines. High-quality evidence is urgently required to inform best practice.

omar Elserafy, N. Kishk, N. T.Abokrysha, N. S.Ghanem, N. M.Elsayed, and S. Alshafey, "Adhesion Molecules (sICAM) and sVCAM) and cerebrovascular risk factors in old cerebrovascular ishemic stroke", the Medical Journal of cairo university, vol. 80, issue 2, pp. 119-124, 2012.
Ebrahim, N., Y. M. H. Mandour, A. S. Farid, E. Nafie, A. Z. Mohamed, M. Safwat, R. Taha, D. Sabry, S. M. Sorour, and A. Refae, "Adipose Tissue-Derived Mesenchymal Stem Cell Modulates the Immune Response of Allergic Rhinitis in a Rat Model.", International journal of molecular sciences, vol. 20, issue 4, 2019 Feb 18. Abstract

This study was designed to investigate the potential effects and underlying mechanism of adipose tissue-derived mesenchymal stem cells (MSCs) on allergic inflammation compared to Montelukast as an antileukotriene drug in a rat model of allergic rhinitis (AR). The effect of MSCs was evaluated in albino rats that were randomly divided into four (control, AR, AR + Montelukast, and AR + MSCs) groups. Rats of AR group were sensitized by ovalbumin (OVA) and then challenged with daily nasal drops of OVA diluted in sterile physiological saline (50 μL/nostril, 100 mg/mL, 10% OVA) from day 15 to day 21 of treatment with/without Montelukast (1 h before each challenge) or MSCs I/P injection (1 × 10⁶ MCSs; weekly for three constitutive weeks). Both Montelukast and MSCs treatment started from day 15 of the experiment. At the end of the 5th week, blood samples were collected from all rats for immunological assays, histological, and molecular biology examinations. Both oral Montelukast and intraperitoneal injection of MSCs significantly reduced allergic symptoms and OVA-specific immunoglobulin E (IgE), IgG1, IgG2a and histamine as well as increasing prostaglandin E2 (PGE2). Further analysis revealed that induction of nasal innate cytokines, such as interleukin (IL)-4 and TNF-α; and chemokines, such as CCL11 and vascular cell adhesion molecule-1 (VCAM-1), were suppressed; and transforming growth factor-β (TGF-β) was up-regulated in Montelukast and MSCs-treated groups with superior effect to MSCs, which explained their underlying mechanism. In addition, the adipose tissue-derived MSCs-treated group had more restoring effects on nasal mucosa structure demonstrated by electron microscopical examination.

Khayyal, M. T., H. Tolba, and M. B. El-Hawary, "Adrenergic responses of the rabbit stomach serosal strip and their modification by monoamine oxidase inhibitors and anti-adrenergic drugs.", The Journal of pharmacy and pharmacology, vol. 28, issue 6, pp. 489-92, 1976 Jun. Abstract

The rabbit stomach serosal strip, was found to contract to adrenaline and noradrenaline but not to isoprenaline. The contractile response could be totally abolished by phenoxybenzamine but was not influenced by propranolol, indicating that the preparation has almost exclusively alpha-adrenoceptors. The responses to adrenaline and noradrenaline were markedly potentiated in the presence of monoamine oxidase inhibitors, guanethidine or reserpine, indicating the presence of MAO activity in the tissue and possible catecholamine stores. The functional state of the latter has not been conclusively established, since tyramine, an indirectly acting amine, was unable to elicit a response qualitatively similar to that of adrenaline, even in the presence of nialamide or tranylcypromine.

Khayyal, M. T., H. Tolba, and M. B. El-Hawary, "Adrenergic responses of the rabbit stomach serosal strip and their modification by monoamine oxidase inhibitors and anti-adrenergic drugs.", The Journal of pharmacy and pharmacology, vol. 28, issue 6, pp. 489-92, 1976 Jun. Abstract

The rabbit stomach serosal strip, was found to contract to adrenaline and noradrenaline but not to isoprenaline. The contractile response could be totally abolished by phenoxybenzamine but was not influenced by propranolol, indicating that the preparation has almost exclusively alpha-adrenoceptors. The responses to adrenaline and noradrenaline were markedly potentiated in the presence of monoamine oxidase inhibitors, guanethidine or reserpine, indicating the presence of MAO activity in the tissue and possible catecholamine stores. The functional state of the latter has not been conclusively established, since tyramine, an indirectly acting amine, was unable to elicit a response qualitatively similar to that of adrenaline, even in the presence of nialamide or tranylcypromine.

Khayyal, M. T., H. Tolba, and M. B. El-Hawary, "Adrenergic responses of the rabbit stomach serosal strip and their modification by monoamine oxidase inhibitors and anti-adrenergic drugs.", The Journal of pharmacy and pharmacology, vol. 28, issue 6, pp. 489-92, 1976 Jun. Abstract

The rabbit stomach serosal strip, was found to contract to adrenaline and noradrenaline but not to isoprenaline. The contractile response could be totally abolished by phenoxybenzamine but was not influenced by propranolol, indicating that the preparation has almost exclusively alpha-adrenoceptors. The responses to adrenaline and noradrenaline were markedly potentiated in the presence of monoamine oxidase inhibitors, guanethidine or reserpine, indicating the presence of MAO activity in the tissue and possible catecholamine stores. The functional state of the latter has not been conclusively established, since tyramine, an indirectly acting amine, was unable to elicit a response qualitatively similar to that of adrenaline, even in the presence of nialamide or tranylcypromine.

Zekri, W., M. Hammad, Y. Elborai, H. Taha, A. Refaat, A. S. Alfaar, B. Abdalla, and A. Younis, "Adrenocortical Carcinoma in the Pediatric Age Group; Experience at Children Cancer Hospital of Egypt (CCHE)", Pediatric Blood & Cancer, vol. 61, issue S1, pp. S35, 2014. pediatric_blood_and_cancer_aspho_abstract_2014.pdf
Zekri, W., M. Hammad, Y. ElBoraie, H. Taha, A. Refaat, A. S. AlFaar, and A. Younis, "Adrenocortical Carcinoma In The Pediatric Age Group; Experience At Children Cancer Hospital Of Egypt (CCHE)", American Society of Pediatric Hematology/Oncology, Chicago, 2014. Abstract
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Zekri, W., M. Hammad, Y. Elborai, H. Taha, A. Refaat, A. Alfaar, B. Abdalla, and A. Younis, "Adrenocortical Carcinoma in the Pediatric Age Group; Experience at Children Cancer Hospital of Egypt (CCHE)", Pediatric Blood & Cancer. DOI: 10.1002/pbc.25032. https://onlinelibrary.wiley.com/doi/epdf/10.1002/pbc.25032, vol. 61, issue S1, no. S1: WILEY-BLACKWELL, pp. S35–S36, 2014. Abstractadrenocortical_carcinoma_in_the_pediatric_age_group_experience_at_children_cancer_hospital_of_egypt_cche.pdf

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Gheita, T. A., R. A. Noor, E. A. Alfadl, O. S. Abousehly, I. I. El-Gazzar, R. R. El Shereef, S. Senara, A. M. Abdalla, N. M. Khalil, A. M. Elsaman, et al., "Adult systemic lupus erythematosus in Egypt: The nation-wide spectrum of 3661 patients and world-wide standpoint.", Lupus, vol. 30, issue 9, pp. 1526-1535, 2021. Abstract

OBJECTIVE: The aim of this study was to present the epidemiology, clinical manifestations and treatment pattern of systemic lupus erythematosus (SLE) in Egyptian patients over the country and compare the findings to large cohorts worldwide. Objectives were extended to focus on the age at onset and gender driven influence on the disease characteristics.

PATIENTS AND METHOD: This population-based, multicenter, cross-sectional study included 3661 adult SLE patients from Egyptian rheumatology departments across the nation. Demographic, clinical, and therapeutic data were assessed for all patients.

RESULTS: The study included 3661 patients; 3296 females and 365 males (9.03:1) and the median age was 30 years (17-79 years), disease duration 4 years (0-75 years) while the median age at disease onset was 25 years (4-75 years). The overall estimated prevalence of adult SLE in Egypt was 6.1/100,000 population (1.2/100,000 males and 11.3/100,000 females).There were 316 (8.6%) juvenile-onset (Jo-SLE) and 3345 adult-onset (Ao-SLE). Age at onset was highest in South and lowest in Cairo (p < 0.0001).

CONCLUSION: SLE in Egypt had a wide variety of clinical and immunological manifestations, with some similarities with that in other nations and differences within the same country. The clinical characteristics, autoantibodies and comorbidities are comparable between Ao-SLE and Jo-SLE. The frequency of various clinical and immunological manifestations varied between gender. Additional studies are needed to determine the underlying factors contributing to gender and age of onset differences.

Vanacker, H., O. Bally, L. Kassem, O. Tredan, P. Heudel, and T. Bachelot, Advanced luminal breast cancer (hormone receptor-positive, HER2 negative): New therapeutic options in 2015, , vol. 102, issue 6 Suppl 1, pp. S47 - 52, 2015. Abstract
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Hassanien, R. H. E., H. O. U. Tian-zhen, L. I. Yu-feng, and L. I. Bao-ming, "Advances in Effects of Sound Waves on Plants", Journal of Integrative Agriculture, vol. 13, issue 2, pp. 335-348, 2014. advances_in_effects_of_sound_waves_on_plants.pdf
Lazarus, J. V., H. E. Mark, Q. M. Anstee, J. P. Arab, R. L. Batterham, L. Castera, H. Cortez-Pinto, J. Crespo, K. Cusi, A. M. Dirac, et al., "Advancing the global public health agenda for NAFLD: a consensus statement.", Nature reviews. Gastroenterology & hepatology, vol. 19, issue 1, pp. 60-78, 2022. Abstract

Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease that affects approximately one-quarter of the global adult population, causing a substantial burden of ill health with wide-ranging social and economic implications. It is a multisystem disease and is considered the hepatic component of metabolic syndrome. Unlike other highly prevalent conditions, NAFLD has received little attention from the global public health community. Health system and public health responses to NAFLD have been weak and fragmented, and, despite its pervasiveness, NAFLD is largely unknown outside hepatology and gastroenterology. There is only a nascent global public health movement addressing NAFLD, and the disease is absent from nearly all national and international strategies and policies for non-communicable diseases, including obesity. In this global Delphi study, a multidisciplinary group of experts developed consensus statements and recommendations, which a larger group of collaborators reviewed over three rounds until consensus was achieved. The resulting consensus statements and recommendations address a broad range of topics - from epidemiology, awareness, care and treatment to public health policies and leadership - that have general relevance for policy-makers, health-care practitioners, civil society groups, research institutions and affected populations. These recommendations should provide a strong foundation for a comprehensive public health response to NAFLD.

Gramoun, A., L. A. Crowe, F. Tobalem, D. Tchernin, B. M. Delattre, K. Grosdemange, M. I. Koenders, W. B. Van den Berg, X. Montet, and J. P. Vallée, "Advantages of Non-invasive Imaging Techniques in Monitoring Antigen Induced Arthritis Rat Model", ANNALS OF THE RHEUMATIC DISEASES, vol. 71: BMJ PUBLISHING GROUP BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND, pp. 488–488, 2012. Abstract
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Rao, J., S. Ashraf, W. Tan, A. T. van der Ven, H. Y. Gee, D. A. Braun, K. Fehér, S. P. George, A. Esmaeilniakooshkghazi, W. - I. Choi, et al., "Advillin acts upstream of phospholipase C ϵ1 in steroid-resistant nephrotic syndrome.", The Journal of clinical investigation, 2017 Oct 23. Abstract

Steroid-resistant nephrotic syndrome (SRNS) is a frequent cause of chronic kidney disease. Here, we identified recessive mutations in the gene encoding the actin-binding protein advillin (AVIL) in 3 unrelated families with SRNS. While all AVIL mutations resulted in a marked loss of its actin-bundling ability, truncation of AVIL also disrupted colocalization with F-actin, thereby leading to impaired actin binding and severing. Additionally, AVIL colocalized and interacted with the phospholipase enzyme PLCE1 and with the ARP2/3 actin-modulating complex. Knockdown of AVIL in human podocytes reduced actin stress fibers at the cell periphery, prevented recruitment of PLCE1 to the ARP3-rich lamellipodia, blocked EGF-induced generation of diacylglycerol (DAG) by PLCE1, and attenuated the podocyte migration rate (PMR). These effects were reversed by overexpression of WT AVIL but not by overexpression of any of the 3 patient-derived AVIL mutants. The PMR was increased by overexpression of WT Avil or PLCE1, or by EGF stimulation; however, this increased PMR was ameliorated by inhibition of the ARP2/3 complex, indicating that ARP-dependent lamellipodia formation occurs downstream of AVIL and PLCE1 function. Together, these results delineate a comprehensive pathogenic axis of SRNS that integrates loss of AVIL function with alterations in the action of PLCE1, an established SRNS protein.

Farahat, A. M., H. Tarek, T. M. Manie, H. M. Abdalla, A. R. Abdalwahab, and N. H. Alieldin, "Aesthetic Outcome after Nipple Sparing Mastectomy for Cancer Patient Egyptian Pattern", Advances in breast cancer research, vol. 6, issue 02, pp. 68-80, 2017. abcr_2017042115322068.pdf
Tawfik, R., "Africa and Sport-mega events: the experience of the 2010 FIFA world cup", The Fourth European Conference on African Studies (ECAS4), Uppsala, Sweden, 16 June, 2011. ecaspaper.pdf
Towab, A. S. M. A., E. A. W. Khalil, Z. A. H. Osman, and Z. Mokhtar, "Age Differences in Physical and Emotional Reactivity to Daily Stressors among Psychiatric Nurses", . Journal of American Science, vol. 8, issue 12, pp. 1501-1507, 2012. Abstract

Stressors encountered in daily life aspects, such as home, and work may increase
physical and emotional reactivity to stress especially in persons working in the
nursing field. Characteristics of the individual as age may limit or increase his
reactivity to daily stressors. The aim of this study is to examine the age differences in
physical and emotional reactivity to daily stressors among nurses working in AlAbbassia
Mental Health Hospital. A descriptive correlational design was utilized for
the current study. Sample of convenience of 100 psychiatric nurses working in AlAbbassia
Mental Health Hospital were divided into two groups "middle age group"
and "young age group". Four tools were utilized in the current study including sociodemographic
Data Sheet, Daily Stressors Scale, Physical Symptoms of Stress Scale,
and Psychological Distress Scale. The results showed that: middle adult group of
nurses reported physical and emotional reactivity to daily stress less than younger
adult group of nurses. The study concludes that, age plays an important role in
controlling emotional and physical reactivity to stress amongnurses working in AlAbbassia
Mental Health Hospital. Further investigation is needed to examine age
groups' difference to stress, as well as, other factors that may be influential in stress
development.