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I, M., D. A, A. A, H. D, and S. T.M, " THE EFFICACY OF CERVICAL LORDOSIS REHABILITATION FOR NERVE ROOT FUNCTION, PAIN, AND SEGMENTAL MOTION IN CERVICAL SPONDYLOTIC RADICULOPATHY", WCPT, Holland, 21 June 2011. Abstract

Purpose: This study was conducted to test the hypothesis that improvement of cervical lordosis in CSR, using 3-point bending traction, will improve the clinical features in a sample population of patients suffering from Cervical Spondylotic Radiculopathy( CSR )with defined cervical hypo-lordosis.
Relevance: This study assists in the understanding of the association between sagittal curve alignment and lasting improved function providing physiotherapists with a guidelines for proper rehabilitation of CSR.
Participants: Thirty patients with lower CSR and with a cervical hypo-lordosis were included in the study. The patients were assigned randomly into two groups of equal number, study and control groups.
Methods: Both groups received stretching exercises and infrared radiation; additionally the study group received 3 point bending cervical traction. Treatments were applied 3 x per week for 10 weeks after which a 12 week follow up was performed. The peak to peak amplitude of dermatomal somatosensory evoked potentials (DSSEPS), absolute rotation angle (ARA C2-C7), cervical flexion-extension kinematics analysis, and visual analogue scale (VAS) were measured for all patients at three intervals (initial, after 10 weeks of treatment, and at follow up of 3 months).
Analysis: The outcome measure of ARA, pain, peak to peak DSSEPS, and kinematics analysis of cervical spine were measured using repeated measures one-way ANOVA to compare measurements made at three intervals.
Results: In the study group, an increase in cervical lordosis (ARA C2-C7) was found (p< 0.0001, F=49.81) and maintained at follow up. No statistically significant improvement in lordosis was found for the control group. A Significant reduction in VAS for study group after 10 weeks of treatment and at 12 weeks follow up was found. In contrast, there was a less significant decrease in post treatment VAS and the follow up measures revealed a significant increase in the VAS score towards initial baseline values. An inverse linear correlation between increased lordosis and VAS was found (r=-.49; p=0.0059) for both groups initially and maintained in the study group post treatment (r=-.6; p=0.0138). At 10-week follow up, we found statistically significant improvements in DSSEPS for both groups (one way ANNOV, p< 0.0001). However, at 12 week post treatment follow up, only the study group showed statistically significant improvement compared to initial (p < 0.006) whereas the control group values returned to baseline measurement (p<0.153). We identified a linear correlation between initial DSSEPs and ARA for both groups (r=.65; p<0.0001), where as this relationship was only maintained in the study group at final follow-up (r=.55; p=0.033).
Conclusions: Improved lordosis in the study group was associated with significant improvements in nerve root function, VAS rating, and translational and rotational motions of the lower cervical spine. Only in the study group were the results maintained at long-term follow up.
Implications: Appropriate physical rehabilitation for CSR should include cervical sagittal curve correction, as it is may to lead greater and longer lasting improved function.
Key-words: 1. cervical sagittal curve 2. 3-point beding traction 3. DSSEPS
Funding acknowledgements: This study was unfunded.
Ethics approval: institutional review board approval was obtained before the study was initiated from Cairo University´s ethics committee.
Session name:
MUSCULOSKELETAL: Spine 2

Programme track/theme:
Professional Practice - MUSCULOSKELETAL: Spine

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El-Tamawy, M. S., T. Z. Tawfik, S. Fathy, R. J. Farid, S. M. Ahmed, G. A. Sleem, and Y. S. Kamal, " The Egyptian Journal of Neurology, Psychiatry and Neurosurgery", The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, vol. 50, issue 2, pp. 195-198, 2013. Abstract2013502014.pdfWebsite

Background: Although Alzheimer’s (AD) dementia was considered to be the most common form of dementia, vascular cognitive impairment has been found to be more common than previously thought. Inflammatory cytokines has been proved to be related to both mild cognitive impairment (MCI) and vascular cognitive impairment (VCI). Objective: Find a difference in inflammatory cytokines between MCI and VCI and the possibility to use them as biomarkers to differentiate between them. Methods: Thirty-seven Egyptian patients with variable degree of cognitive impairment were included. Patients were primary selected using the mini-mental state examination. Patients were divided into two groups (MCI) and (VCI) by NINDS-AIREN criteria and MRI brain. Serum was analyzed for CRP, IL-1B, IL-6 and IL-16 and CSF analyzed for IL-1β, IL-6, IL-16. Results: No difference was found in proportion of patients with abnormally elevated serum level of IL-1β, IL-6, IL-16 and C-reactive protein (CRP) between both groups. IL-6 was found abnormally elevated in a higher proportion of patients with MCI compared to patients with VCI. Conclusion: IL-6 elevation in CSF of MCI may be used as a biomarker to differentiate it from VCI. [Egypt J Neurol Psychiat Neurosurg. 2013; 50(2): 195-198]
Key Words: Mild cognitive impairment, vascular cognitive impairment, cytokines, inteleukin-6.
Correspondence to Shereen Fathi, Department of Neurology, Cairo University, Egypt. Tel.: +201113022610 e-mail: shereenfathi@gmail.com

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Ahmed, E. M., A. T. Taher, R. H. Refaey, Y. M. Nissan, and N. A. Khalil, " Triazolopyridazine derivatives: Synthesis, Cytotoxic evaluation, c-Met Kinase Activity and Molecular Docking", Bioorganic chemistry, vol. 92, pp. 103272, 2019.
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Abdeltawab, H., F. Khalifa, F. Taher, N. S. Alghamdi, M. Ghazal, G. Beache, T. Mohamed, and R. Keynton, "& El-Baz, A.(2020). A deep learning-based approach for automatic segmentation and quantification of the left ventricle from cardiac cine MR images", Computerized medical imaging and graphics, vol. 81, pp. 101717, Submitted. Abstract
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Hagag, S., S. Nasser, N. M. K. Elden, and A. M. Taha, "''Prevalence and determinants of malnutrition among under-five children in a rural village in Giza governorate", Open Access Macedonian Journal of Medical Sciences, vol. 10, issue E, pp. 1125-1131, 2022. malnutrition_paper.pdf
Tawfik, W., M.A.Abdelnaser, L. E. Nadi, and Y. E.Gamal, ''Self –focusing of laser beam in water” proc. Of 4th workshop on plasma and laser physics, , 1996.
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Thabit, S., H. Handoussa, M. Roxo, B. C. de Azevedo, N. S E El Sayed, and M. Wink, "(L.) Schott Fruits Increase Stress Resistance and Exert Antioxidant Properties in and Mouse Models.", Molecules (Basel, Switzerland), vol. 24, issue 14, 2019. Abstractpaper_iii.pdf

(L.) Schott is a popular Asian tree widely used in traditional medicine. The current study explored the potential stress resistance and antioxidant activities of its fruits. Phytochemical profiling of the hydroalcoholic fruit extract was done via high performance liquid chromatography-photodiode array-electrospray ionization-mass/mass (HPLC-PDA-ESI-MS/MS). Twenty four phenolic constituents were tentatively identified in the extract. The () nematode model in addition to trimethyltin (TMT)-induced neurotoxicity mouse model were used for in vivo evaluation of its antioxidant properties. The ability of the extract to enhance stress resistance was manifested through increasing survival rate by 44.7% and decreasing basal reactive oxygen species (ROS) levels by 72.3% in . In addition, the extract increased the levels of the stress response enzyme superoxide dismutase-3 (Sod-3) by 55.5% and decreased the expression of heat shock protein-16.2 (Hsp-16.2) in nematodes, which had been challenged by juglone, by 21%. Using a mouse model, the extract significantly decreased the expression of the oxidative stress marker malondialdehyde (MDA). Furthermore, an elevation in the levels of the antioxidant marker glutathione (GSH), SOD and heme oxygenase-1 (HO-1) enzymes were observed. Our findings imply that has the potential to be used in future studies focusing on diseases associated with oxidative stress.

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Abdel-Lattif1, H. M., M. H. Taha, and M. M. M. Atta, "). Nitrogen Use Efficiency and Grain Protein of Corn Affected by Low Nitrogen Application", Egypt. J. Agron., vol. 41, issue 1, pp. 69-78, 2019.
Sobhy, H. M., H. T.Eshmawy, M. Elgarhy, A. K. Ahmed, and M. I.Mohamed, "): The influence of crop type on soil arthropod funa at El-Saff area, Helwan Governorate,Egypt", Egypt J.Zool.,52:133- 144., vol. 52, pp. 133 - 144, 2009.
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El-Gamal, R., G. Abdel-Maksoud, Sawsan Darwish, Usama Saker, E. Topakas, and P. Christakopoulos, ", FTIR Analysis for the Evaluation of Some Triazole Fungicides for the Treatment of Wooden Artifacts", Mediterranean Archaeology and Archaeometry, vol. 18, issue 2, pp. 141-151 , 2018.
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O.M., E., K. S.S.A, G. T.M, A. E. - A. N.M, and A. - E. A.M, "- Biochemical assessment of a novel fermentation products as antimicrobial antioxidant and anticancer ((In vitro study).", Bell. Fac. Agric., Cairo Univ., (DT12 Conference, Special issue)., vol. 66, issue 5, pp. 42-53, 2015.
Tawfik, N. M., M. A. Hegazy, E. A. A. Maksoud, and A. S. Nasr, "-IRON LOAD AND serum hepcidin in hepatitis C virus related hepatocellular carcinoma", Euroasian journal of hepatology, pp. 1018-1026, 2012.
Tawfik, N. M., M. E. Deeb, and A. S. Nasr, "-Role of soluble P-selectin and methylenetetrahydrofolate reductase gene polymorphisms (677C>T) in Egyptian patients with venous thromboembolism.", Blood Coagul Fibrinolysis., vol. 23, issue 6, pp. 537-542, 2012.
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Tharwat, N., T. Abdel-Rahman, I. M. K. Ismail, E. E. A. Elwi, and M. A. Sayed, ". Fungi isolated from nematode infested soil and their collagenase activity", Egypt. J. Biotechnol., vol. 27, pp. 82-95., 2007.
Tallima, H., M. Aboueldahab, and R. E. Ridi, ". Specific antibodies and arachidonic acid mediate the protection induced by the Schistosoma mansoni cysteine peptidase-based vaccine in mice.", Vaccines (Basel), vol. 8, issue 4, pp. E682, 2020.
TA,  I., H. HM, and E. H. AA, ". Antioxidant potential and phenolic acid content of", Nat.Prod.Research , vol. 24, issue 16, pp. 1537-45, 2010.
Shehata, S. A., S. E. S. Mustafa, and A. Tantawy, ". Effect of some biofertilizers on growth characters and nutritional status of tomato plants", First confeerence of role of Biochemistry in Environment and Agriculture, Biochemistry Dept. of Agric. Cairp Univ. Giza, Egypt., February 6 -8 : , 2001.
and Shehata, S. A., S. E. S. Mustafa, and A. Tantawy, ". Effect of some biofertilizers on the yield and its components and fruit quality of tomato ", First confeerence of role of Biochemistry in Environment and Agriculture February 6 -8 : 312 – 323. , Biochemistry Dept. of Agric. Cairp Univ. Giza, Egypt., February 6 -8 : , 2001.
Taleb, A. A. M., N. A. Tharwat, and R. S. R. El-Mohamedy, ". Induction of resistance in tomato plants against Fusarium crown and root rot disease by Trichoderma hazianum and chitosan.", Egypt. J. Phytopathol., vol. 41, issue (1), pp. 13-26., 2013.
El-Mofty, H., M. Elnabarawi, R. Tag, and M. S. N. L. and Mahmoud Teamia, Mohamed Abary, ". Niosomes: Do They Increase the Potency of Topical Natamycin Ketorolac Formula in Treating Aspergillus Keratitis? An Experimental Study.", Journal Of Ocular Pharmacology And Therapeutics , vol. 36, issue 7, pp. 545-554, 2020.
Sorour, M. H., M. E. M. Sayed, N. A. E. M. Moneem, H. A. Talaat, H. F. Shaalan, and S. E. M. Marsafy, ". Process and financial considerations pertinent to hydrogel manufacture", Starch, vol. 65, issue 5‐6, pp. 527-534, 2013.
Teaima, M. H., Fatma abdelnaby, M. Fadel, M. A. El-Nabarawi, and K. R. Shoueir., ". Synthesis of Biocompatible and Environmentally Nanofibrous Mats Loaded with Moxifloxacin as a Model Drug for Biomedical Applications.", Pharmaceutics, vol. 12, issue 11, pp. E1029, 2020.
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Bamji, C. S., P. O'Connor, T. Elkhatib, S. Mehta, B. Thompson, L. A. Prather, D. Snow, O. C. Akkaya, A. Daniel, and A. D. Payne, "A 0.13 μm CMOS system-on-chip for a 512× 424 time-of-flight image sensor with multi-frequency photo-demodulation up to 130 MHz and 2 GS/s ADC", IEEE Journal of Solid-State Circuits, vol. 50, issue 1: IEEE, pp. 303-319, 2015. Abstract

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