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Eissa, I. H., H. Mohammad, O. A. Qassem, W. Younis, T. M. Abdelghany, A. Elshafeey, M. A. R. M. Moustafa, M. N. Seleem, and A. S. Mayhoub, "{Diphenylurea derivatives for combating methicillin-and vancomycinresistant Staphylococcus aureus}", {EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY}, vol. {130}, {23 RUE LINOIS, 75724 PARIS, FRANCE}, {ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER}, pp. {73-85}, {APR 21}, Submitted. Abstract

{A new class of diphenylurea was identified as a novel antibacterial scaffold with an antibacterial spectrum that includes highly resistant staphylococcal isolates, namely methicillin-and vancomycin-resistant Staphylococcus aureus (MRSA & VRSA). Starting with a lead compound 3 that carries an aminoguanidine functionality from one side and a n-butyl moiety on the other ring, several analogues were prepared. Considering the pharmacokinetic parameters as a key factor in structural optimization, the structureactivity-relationships (SARs) at the lipophilic side chain were rigorously examined leading to the discovery of the cycloheptyloxyl analogue 21n as a potential drug-candidate. This compound has several notable advantages over vancomycin and linezolid including rapid killing kinetics against MRSA and the ability to target and reduce the burden of MRSA harboring inside immune cells (macrophages). Furthermore, the potent anti-MRSA activity of 21n was confirmed in vivo using a Caenorhabditis elegans animal model. The present study provides a foundation for further development of diphenylurea compounds as potential therapeutic agents to address the burgeoning challenge of bacterial resistance to antibiotics. (C) 2017 Elsevier Masson SAS. All rights reserved.}

Victoria, S., H. Amaral, I. Mulamitsi, S. Bhatnagar, H. Moustafa, H. Kartunihardja, F. Sundram, and K. Britton, "CRF on in vivo imaging for infection (sepsis) and inflammation", European Congress Nuclear Medicine, Berlin, 29 Aug- 4 Sept, Submitted.
asmaa hamoda, samah semary, E. Moussa, and omnia hassanien, Burkitts lymphoma is second preinduction phase in critically ill patients important, , dublin, 24/5/2016, Submitted.
H, M., O. WM, S. AH, M. SM, and E. - H. Sh, ": Thallium-201 and Tc99m HMPAO SPECT imaging in brain lesions", IAEA/WHO symposium on tomography in Nuclear Medicine, Present status and future prospects, Vienna, Austria, 21-25 August, Submitted.
Britton, K., S. Solanki, H. Ameral, A. Bhatangar, J. Katamihadja, J. Malamits, M. H, V. Soroa, F. Sundram, D. Warehan, et al., "Imaging of bacterial infection", European congress Nuclear Medicine, Paris , 2-6 September, Submitted.
Moustafa, H., M. Mekawy, M. Said, H. Rabiee, E. Hamada, and H. Zawam, ".: 99mTc -antigranulocyte bone marrow scintigraphy in malignant lymphoma", European congress Nuclear Medicine, Paris , 2 – 6 September, Submitted.
H, M., S. R, Z. G, and E. - H. Sh, "AFP as indicator for diagnosis and management of cancer", Seminar on nuclear techniques for the detection and management of cancer, Colombo, Srilanka, 12-15 August, Submitted.
asmaa hamoda, L. Shalaby, W. Zekry, hany hussien, and A. mostafa, "INCIDENCE AND OUTCOME OF SEPTIC SHOCK IN PEDIATRIC CANCER PATIENTS", EHA, MILAN,ITALY, 12 JUNE, Submitted.
Atroush, D. H. E., D. S. E. G. D. N. Samer, D. S. F. D. A. E. hadedy, and D. H. D. S. M. Mokhtar, " Angiotensin II Receptor Antagonist Effect Versus ACI on Left Ventricular Function In Patients With Acute MI", Kasr El-Aini Medical Journal, vol. 11, issue 3, Submitted.
Ibrahem, D. M., D. A. Mahmoud, D. M. E. Badry, and D. A. E. Shahaby, " Oxidative Stress in Patients with Moderate to Severe Obstructive Sleep Apnea", The Egyptian Journal of Chest diseases and tuberculosis, vol. 58, issue 2, Submitted.
Fadia Zyadaa, M. O. H. A. M. E. D. SHETA, H. E. Degwi, and R. Saad, "Anxiety, depression, and strain among caregivers of terminally ill patients ", Egyptian Journal of Psychiatry , vol. 34:77–84, Submitted. egyptjpsychiatr34277-700959_001140.pdf
El_Hawary, M. S., M. R. E. Abdel-Halim, S. S. Sayed, and H. A. Abdelkader, "Apocytolysis, a proposed mechanism of blister formation in epidermolysis bullosa simplex.", Arch Dermatol Res, vol. 307, issue 4, pp. 371-377, Submitted. 10.10072fs00403-015-1560-4.pdf
Nassar, Y., R. Shash, and M. Saber-Ayad, "Associate Professor", The Egyptian Journal of Chest Diseases and Tuberculosis, Submitted.
IBRAHIUM MOHAMED IBRAHIUM, M. D.;, M. D.; SAMEH AHMED SAKR, and MOHAMED ADEL ELMALLAWANY, Cervical Hooks for Atlanto-Axial Posterior Cervical Fusion, , Submitted.
Husseiny, N. E. M., A. E. Sobky, A. M. Khalaf, M. Fateen, D. E. M. Demerdash, H. Youssef, M. Salah, S. E. S. A. E. Ghany, S. E. Husseiny, and M. Gamil, "Chronic immune thrombocytopenia. Egyptian experience", Comp Clin Pathol , issue 1618-5641, Submitted.
Husseiny, N. E. M., A. E. Sobky, A. M. Khalaf, M. Fateen, D. E. M. Demerdash, H. Youssef, M. Salah, S. E. S. A. E. Ghany, S. E. Husseiny, and M. Gamil, "Chronic immune thrombocytopenia. Egyptian experience", Comp Clin Pathol , issue 1618-5641, Submitted.
EL-Abd, N. E., N. A. Fawzy, S. M. EL-Sheikh, and M. E. Soliman, "Circulating miRNA-122, miRNA-199a, and miRNA-16 as Biomarkers for Early Detection of Hepatocellular Carcinoma in Egyptian Patients with Chronic Hepatitis C Virus Infection", Molecular Diagnosis & Therapy, vol. 19, issue ISSN 1177-1062, pp. 10, Submitted. 10.1007_s40291-015-0148-1.pdf
El-Baky, A. A. A., and Shaymaa I Salem, "Clinicopathological and cytological studies on naturally infected camels and experimentally infected rats with Trypanosoma evansi .", World Applied Sciences Journal , vol. 14, issue 1, pp. 42-50, Submitted.
Shaymaa I Salem, "Clinicopathological studies in canine cutaneous mast cell tumors with and without bone marrow involvement.", Egypt. J. Comp. Path &Clinic Path ., vol. 24, issue 2 , pp. 1-17, Submitted.
Shaymaa I Salem, and A. H. M. Hassan., "Clinicopathological, cytological and histopathological studies on liver and kidney affections in camels.", Global Veterinaria, vol. 7 , issue 6, pp. 557-571, Submitted.
Sayed, S. E. M., R. R. Basheer, and S. F. Bahgat, "COLOR STABILITY AND FRACTURE RESISTANCE OF LAMINATE VENEERS USING DIFFERENT RESTORATIVE MATERIALS AND TECHNIQUES", Egyptian Dental journal, vol. 62, pp. 1-15, Submitted. 7._color_stability_pdf.pdf
Sh, E. - H., M. F, M. H, Z. G, S. Z, and E. - S. K, "Comparative study of interventricular phase difference and pressure gradient in cases of isolated ventricular septal defect", . Eur J Nucl Med, vol. 20(10, pp. 921, Submitted.
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