Export 11688 results:
Sort by: [ Author  (Asc)] Title Type Year
A B C D E F G H I J K L M N O P Q R [S] T U V W X Y Z   [Show ALL]
S, M., E. I, I. T, and G. K, "DASH diet and Cardiovascular risk", Journal of Primary Care and Community Health, vol. 12, pp. 1-8, 2021.
S, O., K. A, S. AE, and M. MN, "Serum Beta-2 Microglobulin: a Possible Marker for Disease Progression in Egyptian Patients with Chronic HCV Related Liver Diseas", Asian Pac J Cancer Prevention, vol. 16, issue 17, pp. 7825-9, 1975 Oct 27, 2015. ahmed_khairy_b2_microglobulin.pdf
S, E., A. DM, H. RA, S. S., and S. MA, "Matrix metalloproteinase in acral and non-acral vitiligo.", Photodermatol Photoimmunol Photomed. 2018 May;34(3)., vol. 34, issue (3), pp. :211-213, 2018.
S, T., G. SM, N. M, N. N, L. D, S. I, and G. TA, "Vascular endothelial growth factor G1612A (rs10434) gene polymorphism and neuropsychiatric manifestations in systemic lupus erythematosus patients.", Rev Bras Reumatol, vol. 57, issue 2, pp. 149-153, 2017. Abstractfinal_accept_published_1-s2.0-s2255502116300980-main.pdfWebsite


To investigate the relation between vascular endothelial growth factor (VEGF) gene polymorphism in systemic lupus erythematosus (SLE) patients and lupus related neuropsychiatric manifestations.

Patients and methods

Sixty adult SLE patients recruited from the Rheumatology and Neurology departments of Cairo University hospitals were classified into two groups; Group A: 30 patients with neuropsychiatric manifestations (NPSLE) and Group B: 30 patients without. For both groups the SNP G1612A (rs10434) of the VEGF gene was genotyped by real time polymerase chain reaction (RT-PCR).


Statistically significant difference was found in genotype and allele frequencies between both groups (AA [70% vs 13.3%, p < 0.001] and GG [10% vs 66.7%, p < 0.001]).


Polymorphism in the gene coding for VEGF may be associated with increased incidence of neuropsychiatric lupus in SLE patients.

S, S. E. - D., F. H. R. L, M. S, and H. R, "Impact of mesenchymal stem cells and Vitamin D on transforming growth factor beta signaling pathway in hepatocellular carcinoma in rats", Asian Pacific Journal of Cancer Prevention, vol. 19 , issue 4, pp. 905-912, 2018.
S, E., B. D, S. MA, AbdelHalim D, H. R, E. H. M, G. H, Gouda H, K. M, and S. N, "Studying the effect of adding growth factors to the autologous melanocyte keratinocyte suspension in segmental vitiligo", Dermatologic Therapy, vol. 33, pp. e13368, 2020.
S, K., E. MS, M. HA, Z. T, Salah M, and E. MA, "Renal recoverability in infants with obstructive calcular anuria: is it better than in older children?", Journal of Pediatric Urology, vol. Dec 2013, issue 9, pp. 1178-82, 2013.
S, S., Kaddah, and E. E, "Epidemiology of primary nephrotic syndrome in Egyptian children", JNephrol, vol. 25, issue 5, pp. 732-737, 2012. epidemiology_of_ns.pdf
S, A. A., M. I. Elenbaawy, Z. A. M. Ahmed, and S. A. Nase, "Incidence Of Mannheimia Haemolytica In Rabbits Farms In Egypt. .1st International Conference ICCPI_VHM_CU.Egypt, 2014.", J.Egyp.Vet.Med.Assoc , vol. 74, issue 4, pp. .635 – 644, 2014. microsoft_word_-__zakia_mona__ahmed_dept.conf_.pdf
S, Z., M. SA, E. - M. S, and A. - R. SS, "Drug induced ototoxicity in Egyptian systemic lupus erythematosus patients", The Egyptian Rheumatologist, vol. ;29(1), pp. 521-32, 2007.
S, E., BahaaS, F. M, and G. HI, "Fractional Carbon Dioxide Laser is Effective in Amelioration of Pruritus in Primary Cutaneous Amyloidosis: A Clinical and Biochemical Study", Lasers Surg Med, vol. in press, issue in press, pp. in press, 2021.
S, L., S. C, N. G, A. ZSO, C. G, E. - B. HA, D. Q, and W. J, "Pharmacological Inhibitors of NAD Biosynthesis as Potential Anticancer Agents", Recent Pat Anticancer Drug Discov., vol. 12, issue 3, pp. 190-207, 2017.
S, E., W. van Geel N, Ezzedine K, Pandya AG, and G. V. B. L. J. E. H. H. J. E. E. L. S. I. A, Bekkenk M, "Validation of a physician global assessment tool for vitiligo extent: Results of an international vitiligo expert meeting.", Pigment Cell Melanoma Res. 2019 Sep;32(5):728-733. doi: 10.1111/pcmr.12784. Epub 2019 May 9., vol. 32, issue 5, pp. 728-733, 2019.
S, E., Heba Ismail Gawdat 1, R. H. A. 1, and E. R. Said, "Different methods of enhancing the efficacy of topical tacrolimus in extra-facial vitiligo: A comparative study", J Cosmet Dermatol ., vol. in press, issue in press, pp. in press, 2021.
S, F., S. A, and E. T. M, "study of fertility in schizophrenia", Current Psychiatry, vol. 10, issue 3, pp. 354-362, 2003.
S, S., E. MF, M. I, E. - S. GS, and R. M, "Aluminium and lead abnormalities in children on haemodialysis: relationship with some medications", Archives of Medical Science, vol. 6, issue 3, pp. 420-429, 2010. aluminium1final_pdf.pdf
S, F., S. Sabet, F. A. Abu Zahra, and A. A. El-Ghor, "Bone marrow derived-mesenchymal stem cells downregulate IL17A dependent IL6/STAT3 signaling pathway in CCl4-induced rat liver fibrosis.", PloS one, vol. 13, issue 10, pp. e0206130, 2018. Abstract

Therapeutic potential of bone marrow-derived mesenchymal stem cells (BM-MSCs) has been reported in several animal models of liver fibrosis. Interleukin (IL) 17A, IL6 and Stat3 have been described to play crucial roles in chronic liver injury. However, the modulatory effect of MSCs on these markers was controversial in different diseases. BM-MSCs might activate the IL6/STAT3 signaling pathway and promote cell invasion in hepatocellular carcinoma, but the immunomodulatory role of BM-MSCs on IL17A/IL6/STAT3 was not fully elucidated in liver fibrosis. In the present study, we evaluated the capacity of the BM-MSCs in the modulation of cytokines milieu and signal transducers, based on unique inflammatory genes Il17a and Il17f and their receptors Il17rc and their effect on the IL6/STAT3 pathway in CCl4-induced liver fibrosis in rats. A single dose of BM-MSCs was administered to the group with induced liver fibrosis, and the genes and proteins of interest were evaluated along six weeks after treatment. Our results showed a significant downregulation of Il17a, Il17ra, il17f and Il17rc genes. In accordance, BM-MSCs administration declined IL17, IL2 and IL6 serum proteins and downregulated IL17A and IL17RA proteins in liver tissue. Interestingly, BM-MSCs downregulated both Stat3 mRNA expression and p-STAT3, while Stat5a gene was downregulated and p-STAT5 protein was elevated. Also P-SMAD3 and TGFβR2 proteins were downregulated in response to BM-MSCs treatment. Collectively, we suggest that BM-MSCs might play an immunomodulatory role in the treatment of liver fibrosis through downregulation of IL17A affecting IL6/STAT3 signaling pathway.