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Patonay, G., W. Abdelwahab, and M. Salim, "Separation and identification of forced degradation products of pharmaceuticals using simple analytical techniques", 252nd ACS National Meeting & Exposition, Philadelphia, PA, United States, pp. ANYL-193, 2016. Abstract
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Patonay, G., G. Chapman, M. Henary, and W. Abdelwahab, "Copolymerized fluorescent silica nanoparticles for labels and molecular recognition", 252nd ACS National Meeting & Exposition, Philadelphia, PA, United States, pp. ANYL-241, 2016. Abstract
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Patonay, G., M. Henary, W. Abdelwahab, and G. Chapman, "Applications of Copolymerized Silica Nanoparticles", SCIX2016, Reno, NV, United States, 2016. Abstract
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Patrick, P., Impact of {SOA} on enterprise information architectures, : ACM, pp. 844 – 848, jun, 2005. Abstract

Enterprises are looking to find new and cost effective means to leverage existing investments in IT infrastructure and incorporate new capabilities in order to improve business productivity. As a means to improve the integration of applications hosted both internal and external to the enterprise, enterprises are turning to Service Oriented Architectures.In this paper, we describe some of the major aspects associated with the introduction of a Service Oriented Architecture and the impact that it can have on an enterprise's information architecture. We outline the concept of exposing data sources as services and discuss the critical integration aspects that need to be addressed including data access, data transformation, and integration into an over arching enterprise security scheme. The paper suggests alternatives, utilizing a Service Oriented Architecture approach, to promote flexible, extensible, and evolvable information architectures.

Patrick, D. A., M. A. Ismail, R. K. Arafa, T. Wenzler, X. Zhu, T. Pandharkar, S. K. Jones, K. A. Werbovetz, R. Brun, D. W. Boykin, et al., "Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives.", Journal of medicinal chemistry, vol. 56, issue 13, pp. 5473-94, 2013 Jul 11. Abstract

4,4″-Diamidino-m-terphenyl (1) and 36 analogues were prepared and assayed in vitro against T rypanosoma brucei rhodesiense , Trypanosoma cruzi , Plasmodium falciparum , and Leishmania amazonensis . Twenty-three compounds were highly active against T. b. rhodesiense or P. falciparum. Most noteworthy were amidines 1, 10, and 11 with IC50 of 4 nM against T. b. rhodesiense, and dimethyltetrahydropyrimidinyl analogues 4 and 9 with IC50 values of ≤ 3 nM against P. falciparum. Bis-pyridylimidamide derivative 31 was 25 times more potent than benznidazole against T. cruzi and slightly more potent than amphotericin B against L. amazonensis. Terphenyldiamidine 1 and dipyridylbenzene analogues 23 and 25 each cured 4/4 mice infected with T. b. rhodesiense STIB900 with four daily 5 mg/kg intraperitoneal doses, as well as with single doses of ≤ 10 mg/kg. Derivatives 5 and 28 (prodrugs of 1 and 25) each cured 3/4 mice with four daily 25 mg/kg oral doses.

Patton, M. Q., Qualitative {Evaluation} and {Research} {Methods}, , 2nd, Newbury Park, CA, Sage Publications, 1990. Abstract

heuristic research, ethnomethodology and symbolic interactionism are approaches derived from phenomenology

Patton, M. Q., How to use qualitative methods in evaluation, , Newbury Park, CA, Sage Publications, 1987. Abstract
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Patton, M. Q., Utilization-{Focused} {Evaluation}, , 2nd, Beverly Hills, California, Sage Publications, 1986. Abstract
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Paul, A. K., M. M. Rahman, M. M. Rahman, M. S. Islam, K. Bork, G. Witzke, J. H. Tidwell, G. Allan, R. C. Summerfelt, R. D. Clayton, et al., "Fatty acid concentration, proximate composition and mineral composition in fishbone flour of Nile Tilapia.", Journal of Fisheries and Aquatic Science, vol. 13, no. 1: orgz, pp. 40–59, 1974. Abstract
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Pavitt, H. L., Y. Aydinok, A. El-Beshlawy, S. Bayraktaroglu, A. S. Ibrahim, M. M. Hamdy, W. Pang, C. Sharples, and T. G. St Pierre, "The effect of reducing repetition time TR on the measurement of liver R2 for the purpose of measuring liver iron concentration.", Magnetic resonance in medicine, vol. 65, issue 5, pp. 1346-51, 2011 May. Abstract

The effects of reducing the pulse repetition time from 2500 ms to 1000 ms when using spin-density-projection-assisted R2-magnetic resonance imaging for the purpose of measuring liver iron concentration were evaluated. Repeated liver R2 measurements were made using both protocols on 60 subjects with liver iron concentrations ranging from 0.5 to 48.6 mg Fe (g dry tissue)(-1). The mean total scan time at repetition time 1000 ms was 42% of that at repetition time 2500 ms. The repeatability coefficients for the two protocols were not significantly different from each other. A systematic difference in the measured R2 using each protocol was found indicating that an adjustment factor is required when one protocol is used to replace the other. The 95% limits of agreement between the two protocols were not significantly different from their repeatability coefficients indicating that the protocols can be interchanged without any significant change in accuracy or precision of liver iron concentration measurement.

Pavitt, H. L., Y. Aydinok, A. El-Beshlawy, S. Bayraktaroglu, A. S. Ibrahim, M. M. Hamdy, W. Pang, C. Sharples, and T. G. St Pierre, "The effect of reducing repetition time TR on the measurement of liver R2 for the purpose of measuring liver iron concentration.", Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 65, issue 5, pp. 1346-51, 2011 May. Abstract

The effects of reducing the pulse repetition time from 2500 ms to 1000 ms when using spin-density-projection-assisted R2-magnetic resonance imaging for the purpose of measuring liver iron concentration were evaluated. Repeated liver R2 measurements were made using both protocols on 60 subjects with liver iron concentrations ranging from 0.5 to 48.6 mg Fe (g dry tissue)(-1). The mean total scan time at repetition time 1000 ms was 42% of that at repetition time 2500 ms. The repeatability coefficients for the two protocols were not significantly different from each other. A systematic difference in the measured R2 using each protocol was found indicating that an adjustment factor is required when one protocol is used to replace the other. The 95% limits of agreement between the two protocols were not significantly different from their repeatability coefficients indicating that the protocols can be interchanged without any significant change in accuracy or precision of liver iron concentration measurement.

Pavulraj, S., M. Kamel, H. Stephanowitz, F. Liu, J. Plendl, N. Osterrieder, and W. Azab, "Equine Herpesvirus Type 1 Modulates Cytokine and Chemokine Profiles of Mononuclear Cells for Efficient Dissemination to Target Organs", Viruses, vol. 12, issue 9, 2020. AbstractWebsite
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Pavulraj, S., M. Kamel, H. Stephanowitz, F. Liu, J. Plendl, N. Osterrieder, and W. Azab, "Equine Herpesvirus Type 1 Modulates Cytokine and Chemokine Profiles of Mononuclear Cells for Efficient Dissemination to Target Organs.", Viruses, vol. 12, issue 9, 2020. Abstract

Equine herpesvirus type 1 (EHV-1) causes encephalomyelopathy and abortion, for which cell-associated viremia and subsequent virus transfer to and replication in endothelial cells (EC) are responsible and prerequisites. Viral and cellular molecules responsible for efficient cell-to-cell spread of EHV-1 between peripheral blood mononuclear cells (PBMC) and EC remain unclear. We have generated EHV-1 mutants lacking , , and genes, either individually or in combination. Mutant viruses were analyzed for their replication properties in cultured equine dermal cells, PBMC infection efficiency, virus-induced changes in the PBMC proteome, and cytokine and chemokine expression profiles. , , and are not essential for virus replication, but deletion resulted in a significant reduction in plaque size. Deletion of and gene significantly reduced cell-to-cell virus transfer from virus-infected PBMC to EC. EHV-1 infection of PBMC resulted in upregulation of several pathways such as Ras signaling, oxidative phosphorylation, platelet activation and leukocyte transendothelial migration. In contrast, chemokine signaling, RNA degradation and apoptotic pathways were downregulated. Deletion of , and modulated chemokine signaling and MAPK pathways in infected PBMC, which may explain the impairment of virus spread between PBMC and EC. The proteomic results were further confirmed by chemokine assays, which showed that virus infection dramatically reduced the cytokine/chemokine release in infected PBMC. This study uncovers cellular proteins and pathways influenced by EHV-1 after PBMC infection and provide an important resource for EHV-1 pathogenesis. EHV-1-immunomodulatory genes could be potential targets for the development of live attenuated vaccines or therapeutics against virus infection.

Payne, R., E. Coderre, W. T. Plunet, J. J. L. Carson, L. P. Renaud, W. Tetzlaff, R. Shamloul, and A. J. Bella, "892 INTERMITTENT CALORIC RESTRICTION MODIFIES NEUROBIOLOGICAL RESPONSE TO BILATERAL CAVERNOUS NERVE CRUSH INJURY IN THE RAT AND FACILITATES RECOVERY OF ERECTILE FUNCTION", The Journal of Urology, vol. 183, no. 4: Elsevier, pp. e348–e349, 2010. Abstract
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Payne, A., A. Daniel, A. Mehta, B. Thompson, C. S. Bamji, D. Snow, H. Oshima, L. Prather, M. Fenton, L. Kordus, et al., "7.6 a 512× 424 cmos 3d time-of-flight image sensor with multi-frequency photo-demodulation up to 130mhz and 2gs/s adc", 2014 IEEE International Solid-State Circuits Conference Digest of Technical Papers (ISSCC): IEEE, pp. 134-135, 2014. Abstract

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Pecinka, A., A. Abdelsamad, and G. T. H. Vu, "Hidden genetic nature of epigenetic natural variation in plants", Trends in Plant Science, vol. 18, issue 11, pp. 625-632, 2013. pecinka_abdelsamad_vu_2013.pdf
Peden, A. E., P. Cullen, K. L. Francis, H. Moeller, M. M. Peden, P. Ye, M. Tian, Z. Zou, S. M. Sawyer, A. Aali, et al., "Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019", The Lancet Public Health, vol. 7, no. 8: Elsevier, pp. e657–e669, 2022. Abstract
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Pedersen, P., and M. M. Megahed, "Axisymmetric element analysis using analytical computing", Computers & Structures, vol. 5, no. 4: Elsevier, pp. 241–247, 1975. Abstract
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Pellegrino R, Schirmacher P1, L. T. 1, E. V, N. O, E. HM, S. MM, Z. AA, G. R, S. P, S. P, and L. T, Protumorigenic role of Timeless in hepatocellular carcinoma, , 2014.
Peltier, S. J., Y. Kadah, S. M. LaConte, and X. Hu, Robust ICA analysis for model-free functional connectivity detection, , vol. 5369, pp. 691–699, 2004. Abstract
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Peng, J., J. - H. Mah, R. Somavat, H. M. H. Mohamed, S. Sastry, and J. Tang, "Thermal Inactivation Kinetics of Bacillus coagulans Spores in Tomato Juice", Journal of Food Protection, vol. 75, pp. 1236-1242, 2012.
Peng, J., A. E. - F. Abomohra, M. Elsayed, X. Zhang, Q. Fan, and P. Ai, "Compositional changes of rice straw fibers after pretreatment with diluted acetic acid: Towards enhanced biomethane production", Journal of Cleaner Production, vol. 230, issue 1 September 2019, pp. 775-782, 2019.
Pennell, D. J., J. B. Porter, M. D. Cappellini, A. El-Beshlawy, L. L. Chan, Y. Aydinok, M. S. Elalfy, P. Sutcharitchan, C. - K. Li, H. Ibrahim, et al., "Efficacy of deferasirox in reducing and preventing cardiac iron overload in beta-thalassemia.", Blood, vol. 115, issue 12, pp. 2364-71, 2010 Mar 25. Abstract

Cardiac iron overload causes most deaths in beta-thalassemia major. The efficacy of deferasirox in reducing or preventing cardiac iron overload was assessed in 192 patients with beta-thalassemia in a 1-year prospective, multicenter study. The cardiac iron reduction arm (n = 114) included patients with magnetic resonance myocardial T2* from 5 to 20 ms (indicating cardiac siderosis), left ventricular ejection fraction (LVEF) of 56% or more, serum ferritin more than 2500 ng/mL, liver iron concentration more than 10 mg Fe/g dry weight, and more than 50 transfused blood units. The prevention arm (n = 78) included otherwise eligible patients whose myocardial T2* was 20 ms or more. The primary end point was the change in myocardial T2* at 1 year. In the cardiac iron reduction arm, the mean deferasirox dose was 32.6 mg/kg per day. Myocardial T2* (geometric mean +/- coefficient of variation) improved from a baseline of 11.2 ms (+/- 40.5%) to 12.9 ms (+/- 49.5%) (+16%; P < .001). LVEF (mean +/- SD) was unchanged: 67.4 (+/- 5.7%) to 67.0 (+/- 6.0%) (-0.3%; P = .53). In the prevention arm, baseline myocardial T2* was unchanged from baseline of 32.0 ms (+/- 25.6%) to 32.5 ms (+/- 25.1%) (+2%; P = .57) and LVEF increased from baseline 67.7 (+/- 4.7%) to 69.6 (+/- 4.5%) (+1.8%; P < .001). This prospective study shows that deferasirox is effective in removing and preventing myocardial iron accumulation. This study is registered at http://clinicaltrials.gov as NCT00171821.

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