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O’KEEFE, T. R., H. B. Graves, and H. S. Siegel, "Social organization in caged layers: the peck order revisited", Poultry science, vol. 67, issue 7: Poultry Science Association, pp. 1008-1014, 1988. Abstract
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O’GRADY, K. E. V. I. N., C. E. Patton, R. H. Victora, R. S. Indeck, D. Melton, B. Dieny, R. Hasegawa, D. C. Jiles, T. D. Lee, Y. Miura, et al., IEEE MAGNETICS SOCIETY, , Submitted. Abstract
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O’Abdulazim, D., A. Fayed, M. M. El-Nokeety, K. Marzouk, A. A. Heikal, H. Hammad, M. M. Naguib, M. M. Salem, and U. S. A. El-Din, "Negative Association between Serum 25 Hydroxy Vitamin D and Serum Uric Acid among Stage 3-5 Chronic Kidney Disease Patients", Annals of Medical and Health Sciences Research, vol. 8, issue 1, 2018. negative-association-between-serum-25-hydroxy-vitamin-d-and-serum-uric-acid-among-stage-35-chronic-kidneydisease-patient.pdf
Ozfatura, E. M., S. ElAzzouni, O. Ercetin, and T. ElBatt, "Optimal throughput performance in full-duplex relay assisted cognitive networks", Springer Wireless Networks, vol. 25, pp. 1931–1947, 2019.
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Özdemir, V., Y. K. Arga, R. K. Aziz, M. Bayram, S. N. Conley, C. Dandara, L. Endrenyi, E. Fisher, C. K. Garvey, and N. Hekim, Digging Deeper into Precision/Personalized Medicine: Cracking the Sugar Code, the Third Alphabet of Life, and Sociomateriality of the Cell, , vol. 24, issue 2: Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New …, pp. 62 - 80, 2020. Abstract
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Özdemir, V., Y. K. Arga, R. K. Aziz, M. Bayram, S. N. Conley, C. Dandara, L. Endrenyi, E. Fisher, C. K. Garvey, N. Hekim, et al., "Digging Deeper into Precision/Personalized Medicine: Cracking the Sugar Code, the Third Alphabet of Life, and Sociomateriality of the Cell", OMICS: A Journal of Integrative Biology, vol. 24, no. 2, pp. 62-80, 2020. AbstractWebsite

Precision/personalized medicine is a hot topic in health care. Often presented with the motto “the right drug, for the right patient, at the right dose, and the right time,” precision medicine is a theory for rational therapeutics as well as practice to individualize health interventions (e.g., drugs, food, vaccines, medical devices, and exercise programs) using biomarkers. Yet, an alien visitor to planet Earth reading the contemporary textbooks on diagnostics might think precision medicine requires only two biomolecules omnipresent in the literature: nucleic acids (e.g., DNA) and proteins, known as the first and second alphabet of biology, respectively. However, the precision/personalized medicine community has tended to underappreciate the third alphabet of life, the “sugar code” (i.e., the information stored in glycans, glycoproteins, and glycolipids). This article brings together experts in precision/personalized medicine science, pharmacoglycomics, emerging technology governance, cultural studies, contemporary art, and responsible innovation to critically comment on the sociomateriality of the three alphabets of life together. First, the current transformation of targeted therapies with personalized glycomedicine and glycan biomarkers is examined. Next, we discuss the reasons as to why unraveling of the sugar code might have lagged behind the DNA and protein codes. While social scientists have historically noted the importance of constructivism (e.g., how people interpret technology and build their values, hopes, and expectations into emerging technologies), life scientists relied on the material properties of technologies in explaining why some innovations emerge rapidly and are more popular than others. The concept of sociomateriality integrates these two explanations by highlighting the inherent entanglement of the social and the material contributions to knowledge and what is presented to us as reality from everyday laboratory life. Hence, we present a hypothesis based on a sociomaterial conceptual lens: because materiality and synthesis of glycans are not directly driven by a template, and thus more complex and open ended than sequencing of a finite length genome, social construction of expectations from unraveling of the sugar code versus the DNA code might have evolved differently, as being future-uncertain versus future-proof, respectively, thus potentially explaining the “sugar lag” in precision/personalized medicine diagnostics over the past decades. We conclude by introducing systems scientists, physicians, and biotechnology industry to the concept, practice, and value of responsible innovation, while glycomedicine and other emerging biomarker technologies (e.g., metagenomics and pharmacomicrobiomics) transition to applications in health care, ecology, pharmaceutical/diagnostic industries, agriculture, food, and bioengineering, among others.

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Ozdemir, V., D. S. Rosenblatt, L. Warnich, S. Srivastava, G. O. Tadmouri, R. K. Aziz, P. J. Reddy, A. Manamperi, E. S. Dove, Y. Joly, et al., "Towards an ecology of collective innovation: Human variome project (HVP), rare disease consortium for autosomal loci (RADical) and data-enabled life sciences alliance (DELSA)", Current pharmacogenomics and personalized medicine, vol. 9, no. 4: PMC Canada manuscript submission, pp. 243, 2011. Abstract
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Ozdemir, V., J. Armengaud, L. Dubé, R. K. Aziz, and B. M. Knoppers, "Nutriproteomics and proteogenomics: Cultivating two novel hybrid fields of personalized medicine with added societal value", Current pharmacogenomics and personalized medicine, vol. 8, no. 4: PMC Canada manuscript submission, pp. 240, 2010. Abstract
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Ozdemir, V., D. S. Rosenblatt, L. Warnich, S. Srivastava, G. O. Tadmouri, R. K. Aziz, and et al, "Towards an Ecology of Collective Innovation: Human Variome Project (Hvp), Rare Disease Consortium for Autosomal Loci (Radical) and Data-Enabled Life Sciences Alliance (Delsa)", Current Pharmacogenomics and Personalized Medicine, 2011. Abstract

The Millennium Summit in 2000 established the Millennium Development Goals (MDGs), which were agreed upon by 193 countries and 23 international organizations to combat extreme poverty and other pressing global priorities for human development. In the December 2011 issue of CPPM, Borda-Rodriguez and Huzair present an analysis of the close ties and synergies among the MDGs, pharmacogenomics and personalized medicine. Notably, MDGs promote the creation of collective innovation, a concept with both substantive and instrumental pertinence for the personalized medicine R&D that is currently undergoing rapid globalization. The ethos for collective innovation in global health is also embodied in the Paris Declaration on Aid Effectiveness, endorsed in 2005 by more than 100 signatories, including donor and developing country governments, regional development banks and international aid agencies.

Ozarslan, M. A. -, Y. Ibrahim, C. Ozcan, and M. Yousif, "C4- and D4-Modules via Perspective Direct Summands", Communications In Algebra, vol. 46, issue 10, pp. 4480–4497, 2018.
Oyoun, H. A., Maha Abou-Elew, M. Mosleh, H. Fathy, W. Wageeh, and M. E. A. Hassan, "Systemic Steroids and Intratympanic Steroid Perfusion as an Initial Therapy for Idiopathic Sudden Sensorineural Hearing Loss, a comparative study", The Egyptian Journal of Otolaryngology, vol. 30, pp. 215-219, 2014.
Oyoun, L. M. I., E. M. Almatha, and H. S. M. Gabr, "Effect of Neem Azal (Azadirachta indica) extracts on the mortality and fecundity of Hyalomma dromedraii females.", Acarines, vol. 5, issue 1: Egyptian Society of Acarology, pp. 7-10, 2011. Abstract
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Owolabi, M. O., A. G. Thrift, S. Martins, W. Johnson, J. Pandian, F. Abd-Allah, C. Varghese, A. Mahal, J. Yaria, H. T. Phan, et al., "The state of stroke services across the globe: Report of World Stroke Organization-World Health Organization surveys.", International journal of stroke : official journal of the International Stroke Society, vol. 16, issue 8, pp. 889-901, 2021. Abstract

BACKGROUND: Improving stroke services is critical for reducing the global stroke burden. The World Stroke Organization-World Health Organization- Commission on Stroke conducted a survey of the status of stroke services in low and middle-income countries (LMICs) compared to high-income countries.

METHODS: Using a validated World Stroke Organization comprehensive questionnaire, we collected and compared data on stroke services along four pillars of the stroke quadrangle (surveillance, prevention, acute stroke, and rehabilitation) in 84 countries across World Health Organization regions and economic strata. The World Health Organization also conducted a survey of non-communicable diseases in 194 countries in 2019.

RESULTS: Fewer surveillance activities (including presence of registries, presence of recent risk factors surveys, and participation in research) were reported in low-income countries than high-income countries. The overall global score for prevention was 40.2%. Stroke units were present in 91% of high-income countries in contrast to 18% of low-income countries (p < 0.001). Acute stroke treatments were offered in ∼ 60% of high-income countries compared to 26% of low-income countries (p = 0.009). Compared to high-income countries, LMICs provided less rehabilitation services including in-patient rehabilitation, home assessment, community rehabilitation, education, early hospital discharge program, and presence of rehabilitation protocol.

CONCLUSIONS: There is an urgent need to improve access to stroke units and services globally especially in LMICs. Countries with less stroke services can adapt strategies from those with better services. This could include establishment of a framework for regular monitoring of stroke burden and services, implementation of integrated prevention activities and essential acute stroke care services, and provision of interdisciplinary care for stroke rehabilitation.

Own, H., and A. E. Hassanien, "Automatic Image Registration Algorithm Based on Multiresolution Local Contrast Entropy and Mutual Information", International Journal of Computers and Their Applications, vol. 12, issue 1, pp. 9-15, 2005.
Own, H., and A. Hassanien, "Q-shift Complex Wavelet-based Image Registration Algorithm", Computer Recognition Systems: Springer Berlin/Heidelberg, pp. 403–410, 2005. Abstract
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Own, H. S., and A. E. Hassanien, "Rough Wavelet Hybrid Image Classification Scheme", Journal of Convergence Information Technology, vol. 3, issue 4, pp. 65-75, 2008. AbstractWebsite

This paper introduces a new computer-aided classification system for detection of prostate cancer in
Transrectal Ultrasound images (TRUS). To increase the efficiency of the computer aided classification
process, an intensity adjustment process is applied first, based on the Pulse Coupled Neural Network
(PCNN) with a median filter. This is followed by applying a PCNN-based segmentation algorithm to
detect the boundary of the prostate image. Combining the adjustment and segmentation enable to eliminate PCNN sensitivity to the setting of the various PCNN parameters whose optimal selection can be difficult and can vary even for the same problem. Then, wavelet based features have been extracted and
normalized, followed by application of a rough set analysis to discover the dependency between the
attributes and to generate a set of reduct that contains a minimal number of attributes. Finally, a rough
confusion matrix is designed that contain information about actual and predicted classifications done by a
classification system. Experimental results show that the introduced system is very successful and has high detection accuracy

Own, H., and A. Hassanien, "Q-shift Complex Wavelet-based Image Registration Algorithm", Computer Recognition Systems: Springer Berlin/Heidelberg, pp. 403–410, 2005. Abstract
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Own, H., and A. E. Hassanien, "Q-shift Complex Wavelet-based Image Registration Algorithm", Proceedings of the 4th International Conference on Computer Recognition Systems, CORES'05, pp. 403-410, Rydzyna Castle, Poland, May 22-25,, 2005. Abstract

This paper presents an efficient image registration technique using the Q-shift complex wavelet transform (Q-shift CWT). It is chosen for its key advantages compared to other wavelet transforms; such as shift invariance, directional selectivity, perfect reconstruction, limited redundancy and efficient computation. The experiments show that the proposed algorithm improves the computational efficiency and yields robust and consistent image registration compared with the classical wavelet transform.

Own, H. S., N. I. GHALL, and E. L. L. A. H. A. S. S. A. N. I. E. N. ABOUL, "Hybrid Dual-Tree Wavelet Transform and Adaptive Threshold for Image Denoising", International journal of imaging and robotics, vol. 9, no. 1: CESER Publications, pp. 17–25, 2013. Abstract
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Own, H. S., and A. E. Hassanien, "Rough wavelet hybrid image classification scheme", Journal of Convergence Information Technology, vol. 3, no. 4, pp. 65–75, 2008. Abstract
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Own, H. S., and A. E. Hassanien, "Multiresolution image registration algorithm in wavelet transform domain", Digital Signal Processing, 2002. DSP 2002. 2002 14th International Conference on, vol. 2: IEEE, pp. 889–892, 2002. Abstract
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Own, H. S., and A. E. Hassanien, "Rough wavelet hybrid image classification scheme", Journal of Convergence Information Technology, vol. 3, no. 4, pp. 65–75, 2008. Abstract
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Own, H. S., N. I. GHALL, and E. L. L. A. H. A. S. S. A. N. I. E. N. ABOUL, "Hybrid Dual-Tree Wavelet Transform and Adaptive Threshold for Image Denoising", International journal of imaging and robotics, vol. 9, no. 1: CESER Publications, pp. 17–25, 2013. Abstract
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Own, H. S., and A. E. Hassanien, "Rough wavelet hybrid image classification scheme", Journal of Convergence Information Technology, vol. 3, no. 4, pp. 65–75, 2008. Abstract
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Owis, M., A. H. Abou-Zied, A. - B. M. Youssef, Y. M. Kadah, and others, "Study of features based on nonlinear dynamical modeling in ECG arrhythmia detection and classification", Biomedical Engineering, IEEE Transactions on, vol. 49, no. 7: IEEE, pp. 733–736, 2002. Abstract
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