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Okasha, H. H., M. Mansour, K. A. Attia, H. M. Khattab, A. Y. Sakr, M. N. Abdalla, W. Aref, A. A. - M. Al-Naggar, and R. Ezzat, "Role of high resolution ultrasound/endosonography and elastography in predicting lymph node malignancy", Endoscopic Ultrasound Journal, vol. 3, issue 1, pp. 58-62, 2014. role_of_hrus-eus_and_elastgraphy_in_predicting_ln_malignancy.pdf
Okasha, L. A., A. A, M. A. El-Hady, S. A, S. A.A, A. M, and E. - J. J, "Identification of common fish bacterial pathogens in Kafr el Sheikh Governorate Egypt using PCR", IJBPAS, February,, vol. 5(2):, pp. 522-537., 2016.
Okasha, T. M., and H. Ibrahim, Clinical pathway for postoperative organ transplants, , Germany , LAP LAMBERT , 2014. 978-3-659-58969-0_coverpreview_1.pdf
Okasha, H., S. Elkholy, R. Ezzat, and A. El-Kafrawi, "Isolated Pulmonary Valve Vegetations in a Patient with Gastric Lymphoma Diagnosed by Endoscopic Ultrasound", Acta Gastro-Enterologica Belgica, vol. 80, pp. 430-431, 2017.
Okasha, H., S. Elkholy, R. El-Sayed, M. - N. Wifi, M. El-Nady, W. El-Nabawi, W. A. El-Dayem, M. I. Radwan, A. L. I. FARAG, Y. El-sherif, et al., "Real time endoscopic ultrasound elastography and strain ratio in the diagnosis of solid pancreatic lesions.", World journal of gastroenterology, vol. 23, issue 32, pp. 5962-5968, 2017. Abstract

AIM: To evaluate the accuracy of the elastography score combined to the strain ratio in the diagnosis of solid pancreatic lesions (SPL).

METHODS: A total of 172 patients with SPL identified by endoscopic ultrasound were enrolled in the study to evaluate the efficacy of elastography and strain ratio in differentiating malignant from benign lesions. The semi quantitative score of elastography was represented by the strain ratio method. Two areas were selected, area (A) representing the region of interest and area (B) representing the normal area. Area (B) was then divided by area (A). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were calculated by comparing diagnoses made by elastography, strain ratio and final diagnoses.

RESULTS: SPL were shown to be benign in 49 patients and malignant in 123 patients. Elastography alone had a sensitivity of 99%, a specificity of 63%, and an accuracy of 88%, a PPV of 87% and an NPV of 96%. The best cut-off level of strain ratio to obtain the maximal area under the curve was 7.8 with a sensitivity of 92%, specificity of 77%, PPV of 91%, NPV of 80% and an accuracy of 88%. Another estimated cut off strain ratio level of 3.8 had a higher sensitivity of 99% and NPV of 96%, but with less specificity, PPV and accuracy 53%, 84% and 86%, respectively. Adding both elastography to strain ratio resulted in a sensitivity of 98%, specificity of 77%, PPV of 91%, NPV of 95% and accuracy of 92% for the diagnosis of SPL.

CONCLUSION: Combining elastography to strain ratio increases the accuracy of the differentiation of benign from malignant SPL.

Okasha, H., S. Elkholy, M. Sayed, M. El-Sherbiny, R. El-Hussieny, E. El-Gemeie, W. Al-Nabawy, M. S. Mohamed, and Y. Elsherif, "Ultrasound, endoscopic ultrasound elastography, and the strain ratio in differentiating benign from malignant lymph nodes.", Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology, vol. 19, issue 1, pp. 7-15, 2018. Abstract

BACKGROUND AND STUDY AIMS: Endoscopic ultrasound elastography (EUS-elastography), or sono-elastography, has emerged in the past 2 decades as a qualitative method of estimating tissue stiffness. Strain elastography allows for semi-quantitative measurements of the average elasticity of a lesion, and previous studies have proposed the strain ratio (SR) for overcoming the limitations of the elasticity score. The main objective of this study is to assess the specificity, sensitivity and predictive values of the SR measured by EUS-elastography in differentiating benign from malignant lymph nodes (LNs). This study also aims to find significant ultrasonographic features other than the SR which could help in predicting LN malignancy.

PATIENTS AND METHODS: This prospective study included 126 Egyptian patients with lymphadenopathy. US and EUS-elastography and the SR were assessed, in addition to detailed sonographic features, including size, longest diameter, shortest diameter, ratio of shortest/longest diameter, echotexture (echogenic or echo-poor) and hilum (lost or preserved).

RESULTS: The SR cut-off value of 4.61 showed a sensitivity and specificity of 89.8% and 83.3%, respectively. This parameter had high positive and negative predictive values of 82.5% and 90.2%, respectively, for predicting malignant LNs. Univariate regression analysis showed that echogenicity, hilum preservation, elastography, the shortest dimension, the ratio of the shortest/longest dimension, ultrasound diagnosis and SR could be potential predictors of the final lymph node diagnosis. Sono-diagnosis depending on echogenicity, the shortest/longest diameter ratio and a preserved hilum in combination was the only predictive parameter in multivariate regression analysis.

CONCLUSION: EUS-elastography and the SR could be excellent prognostic indices in differentiating benign from malignant lymph nodes if combined with other US features.

Okasha, H., M. Wahba, H. A. El-Fol, and Y. Elsherif, "Preoperative EUS-guided tattooing of a small, firm, deep pancreatic mass.", Gastrointestinal endoscopy, vol. 93, issue 3, pp. 769-771, 2021.
OKBA, M. O. N. A. M., P. M. AbdelBaki, A. E. Khaleel, M. M. El-Sherei, and M. A. Salem, "Discrimination of common Iris species from Egypt based on their genetic and metabolic profiling", Phytochemical Analysis, vol. 32, issue 2, pp. 172-182, 2021.
OKBA, M. O. N. A. M., F. A. T. H. Y. M. SOLIMAN, K. A. D. R. I. Y. A. E. L. S. DEEB, and M. F. Yousif, "BOTANICAL STUDY, DNA FINGERPRINTING, NUTRITIONAL VALUES AND CERTAIN PROXIMATES OF ENTADA RHEEDII SPRENG", International Journal of Pharmacy and Pharmaceutical Sciences, vol. 5, issue 3, pp. 311-329, 2013.
OKBA, M. O. N. A. M., S. E. A. W. Awdan, M. F. Yousif, K. A. D. R. I. Y. A. E. L. S. DEEB, and F. A. T. H. Y. M. SOLIMAN, "Entada rheedii Seeds Thioamides, Phenolics, and Saponins and Its Antiulcerogenic and Antimicrobial Activities", Journal of Applied Pharmaceutical Science, vol. 8, issue 05, pp. 101-108, 2018. entada_chemistry.pdf
Okba, M., O. Sabry, L. Maes, and E. Abdel-Sattar, "In vitro antiprotozoal Activity of Some Medicinal Plant Extracts Against Sleeping Sickness, Chagas Disease, and Leishmaniasis ", Future Medicinal Chemistry , vol. 10, issue 22, pp. 2607-2617, 2018. 10-in_vitro_antiprotozoal_activity_of_some.pdf
OKBA, M. O. N. A. M., O. M. Sabry, A. Matheeussen, and E. Abdel-Sattar, "In vitro antiprotozoal activity of some medicinal plants against sleeping sickness, Chagas disease and leishmaniasis", Future medicinal chemistry, vol. 10, no. 22: Future Science Ltd London, UK, pp. 2607–2617, 2018. Abstract
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OKBA, M. O. N. A. M., M. F. Yousif, K. A. D. R. I. Y. A. E. L. S. DEEB, and F. A. T. H. Y. M. SOLIMAN, "BOTANICAL STUDY, DNA FINGERPRINTING, TOTAL PROTEIN PROFILING, NUTRITIONAL VALUES AND CERTAIN PROXIMATES OF V. ERVILIA L.", International Journal of Pharmacy and Pharmaceutical Sciences, vol. 6, issue 1, pp. 246-253, 2014. vicia_botany_paper_2014.pdf
OKBA, M. O. N. A. M., O. M. Sabry, A. Matheeussen, and E. Abdel-Sattar, "In vitro antiprotozoal activity of some medicinal plants against sleeping sickness, Chagas disease and leishmaniasis", Future medicinal chemistry, vol. 10, issue 22, pp. 2607-2617, 2018. anti_protozoa_paper.pdf
OKBA, M. O. N. A. M., M. F. Yousif, K. A. D. R. I. Y. A. E. L. S. DEEB, and F. A. T. H. Y. M. SOLIMAN, "Correlation Between Vicia ervilia L. Willd. Antibacterial Activity and Its Phenolic Content", Journal of Natural Sciences Research, vol. 6, issue 22, 2016. v_seeds_tpc__antibacterial.pdf
Okba, M., R. El-Shiekh, M. Abu-Elghait, M. Sobeh, and R. Ashour, "HPLC-PDA-ESI-MS/MS Profiling and Anti-Biofilm Potential of Eucalyptussideroxylon Flowers", Antibiotics, vol. 10, issue 761, 2021.
OKBA, M. O. N. A. M., P. A. M. Baki, A. E. Khaleel, M. M. El-Sherei, and M. A. Salem, Discrimination of common Iris species from Egypt based on their genetic and metabolic profiling, , 2020.
Okebiorun, M. O., and S. H. ElGohary, "Optothermal tissue response for laser-based investigation of thyroid cancer", Informatics in Medicine Unlocked, vol. 18, pp. 100285, 2019. 1-s2.0-s2352914819303399-main.pdf
Okebiorun, M. O., and S. H. ElGohary, "Optothermal tissue response for laser-based investigation of thyroid cancer", Informatics in Medicine Unlocked, vol. 18: Elsevier, pp. 100285, 2020. Abstract
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Okebiorun, M. O., and S. H. ElGohary, "Optothermal response and Tissue Damage analysis during Laser Hair Removal", Journal of Physics: Conference Series, vol. 1472, no. 1: IOP Publishing, pp. 012003, 2020. Abstract
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Okello, E., D. R. Williams, W. R. ElAshmawy, J. Adams, R. V. Pereira, T. W. Lehenbauer, and S. S. Aly, "Survey on Antimicrobial Drug Use Practices in California Preweaned Dairy Calves", Front Vet Sci, vol. 2021 Apr 22, issue 8, pp. 636670, 2021. Abstract

The California (CA) dairy industry was surveyed in July 2017 to evaluate producers' knowledge and perceptions and antimicrobial drug (AMD) use in preweaned dairy calves following the implementation of the nationwide veterinary feed directive final rule (VFD) in January 2017 and prior to statewide implementation of CA Senate Bill (SB) 27 in January 2018. Together, these regulations require veterinary oversight for all uses of medically important antimicrobial drugs (MIADs) administered to livestock in CA. Survey questionnaire was mailed to 1,361 CA Grade A milk producing dairies and calf ranches across CA resulting in a 12% (169) response. Most respondents (83%) were aware of the VFD and SB 27 changes. Use of antibiotics was perceived as important (77%) in raising preweaned dairy calves and judicious use of antibiotics was ranked as the most important antimicrobial stewardship practice, amongst record keeping, observing withdrawal periods, having a valid Veterinarian-Client-Patient-Relationship (VCPR), and use of alternatives to antibiotics. Treating sick calves was the major indication for AMD use (90.5%); however, few producers reported use of antibiotics to control (12.7%) or prevent disease (11%). Neomycin sulfate, chlortetracycline, oxytetracycline and sulfamethazine were the most used AMD. The respondents reported a decreased use of AMD in milk (10%) and in solid feed (5%), and discontinuation of one or more AMDs used in milk (18.6%) or in solid feed (5%) post-VFD rule implementation in 2017. Most respondents reported keeping treatment records and the information recorded included date (82%), dose (44%) and route (15%) of AMD used. A few respondents reported they had initiated use of alternatives to AMDs, such as vitamins (32.6%), minerals (25.6%), herbal remedies (11.6%) and pathogen specific antibodies (7%), post-VFD. The limited changes noted in AMD use could be attributed to the short period between the implementation of the VFD and the time of the survey. Our study outcomes identified opportunities to improve AMD use practices, including record keeping and use of AMD alternatives, and provides a baseline for future evaluation of the impact of these regulatory changes, as well as guidance for the future recommendations on best practices to promote judicious AMD use.