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Oguntimein, B., T. S. El-Alfy, and M. A. Elsohly, "Volatile oils of Zanthoxylum rigidifolium and Zanthoxylum gilletii", Fitoterapia, 1985. Abstract
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Ogunyemi, O. M., G. A. Gyebi, I. M. Ibrahim, C. O. Olaiya, J. O. Ocheje, M. M. Fabusiwa, and J. O. Adebayo, "Dietary stigmastane-type saponins as promising dual-target directed inhibitors of SARS-CoV-2 proteases: a structure-based screening", RSC Advances, vol. 11, no. 53: Royal Society of Chemistry, pp. 33380–33398, 2021. Abstract
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Ogunyemi, O. M., G. A. Gyebi, A. A. Elfiky, S. O. Afolabi, O. B. Ogunro, A. P. Adegunloye, and I. M. Ibrahim, "Alkaloids and flavonoids from African phytochemicals as potential inhibitors of SARS-Cov-2 RNA-dependent RNA polymerase: an in silico perspective", Antiviral Chemistry and Chemotherapy, vol. 28: SAGE Publications Sage UK: London, England, pp. 2040206620984076, 2020. Abstract
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Ogunyemi, O. M., G. A. Gyebi, I. M. Ibrahim, A. M. Esan, C. O. Olaiya, M. M. Soliman, and G. E. - S. Batiha, "Identification of promising multi-targeting inhibitors of obesity from Vernonia amygdalina through computational analysis", Molecular Diversity: Springer, pp. 1–25, 2022. Abstract
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Ogunyemi, O. M., G. A. Gyebi, A. A. Elfiky, S. O. Afolabi, O. B. Ogunro, A. P. Adegunloye, and I. M. Ibrahim, "Alkaloids and flavonoids from African phytochemicals as potential inhibitors of SARS-Cov-2 RNA-dependent RNA polymerase: an in silico perspective", Antiviral Chemistry and Chemotherapy, vol. 28, 2020. Abstract
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Oh, J. Y., M. Mannaa, G. D. Han, S. - C. Chun, and K. D. Kim, "First report of Aspergillus awamori as a fungal pathogen of garlic (Allium sativum L.)", Crop Protection, vol. 85: Elsevier, pp. 65-70, 2016. Abstract
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Oh, J. Y., M. Mannaa, G. D. Han, S. - C. Chun, and K. D. Kim, "First report of Aspergillus awamori as a fungal pathogen of garlic (Allium sativum L.)", Crop Protection, vol. 85: Elsevier, pp. 65-70, 2016. Abstract
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Ohashi, Y., H. Ibrahim, L. Furtado, J. Kingdom, and J. C. Carvalho, "Non-invasive Hemodynamic Assessment of Non-pregnant, Healthy Pregnant, and Preeclamptic Women Using Bio-Reactance. ", Rev Bras Anestesiol, vol. 60, issue 6, pp. 603-613, 2010.
Ohmori, T., M. S. El-Deab, and M. Osawa, "Electroreduction of Nitrate Ion to Nitrite and Ammonia on a Gold Electrode in Acidic and Basic Sodium and Cesium Nitrate Solutions", Journal of Electroanalytical Chemistry, vol. 470, pp. 46-52, 1999.
Ohmura, S., K. Nagaya, F. Shimojo, and M. Yao, "Ab Initio MOLECULAR-DYNAMICS STUDY OF NONEQUILIBRIUM PHENOMENA IN DISORDERED MATERIALS", MODELS IN BIOSCIENCE AND MATERIALS RESEARCH, pp. 1, Submitted. Abstract
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Ohmura, S., K. Nagaya, F. Shimojo, and M. Yao, "Ab Initio MOLECULAR-DYNAMICS STUDY OF NONEQUILIBRIUM PHENOMENA IN DISORDERED MATERIALS", MODELS IN BIOSCIENCE AND MATERIALS RESEARCH, pp. 1, Submitted. Abstract
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Ohnsorge, J. A. K., K. H. Salem, A. Ladenburger, U. M. Maus, and M. Weißkopf, "Computer-assisted fluoroscopic navigation of percutaneous spinal interventions", European Spine Journal, vol. 22, no. 3: Springer-Verlag, pp. 642-647, 2013. AbstractWebsite
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Ohsaka, T., and M. S. El-Deab, "Development of non-platinum-based electrocatalysts for oxygen reduction", Recent Research Developments in Electrochemistry, Kerala, Transworld Research Network, 2004.
Ohsaka, T., and M. S. El-Deab, "Electrocatalysis by Nanoparticles: Fabrication and Electrochemical Applications of Tailor-Designed Nanoparticles-Based Electrocatalysts", Electrochemistry (Japan), vol. 75, issue 11, pp. 858-866, 2007.
Ohtsuka, N., M. E. Shabshiry, M. Ismail, A. Faessler, and J. Aichelin, "Does photon production in heavy-ion collisions depend on the equation of state?", Journal of Physics G: Nuclear and Particle Physics, vol. 16, no. 8, pp. L155-L161, 1990. AbstractWebsite

Photon production cross sections in 12C-12C and 40Ca-40Ca collisions at Elab=84 and 200 MeV/A are calculated in the framework of the quantum molecular dynamics approach using the medium-dependent NN cross section obtained from the G matrix. Photons are assumed to be produced by incoherent pn bremsstrahlung and a simple classical expression for the production cross section is used. The effects of the equation of state for nuclear matter on the photon production cross section are studied in detail. In the 12C-12C collision, the authors found little difference in the photon cross section due to differences in the equation of state both at 84 and 200 MeV/A. In the 40Ca-40Ca collision, slightly more high-energy photons are produced in the case of the soft equation of state and the difference is slightly larger at higher incident energies.

Oing, C., I. Verem, W. Y. Mansour, C. Bokemeyer, S. Dyshlovoy, and F. Honecker, "5-Azacitidine Exerts Prolonged Pro-Apoptotic Effects and Overcomes Cisplatin-Resistance in Non-Seminomatous Germ Cell Tumor Cells.", International journal of molecular sciences, vol. 20, issue 1, pp. 21-32, 2018 Dec 21, 2019. Abstract

Despite high cure rates, about 20% of patients with advanced germ cell tumors (GCTs) fail cisplatin-based chemotherapy. High levels of DNA methylation have been identified in GCTs and linked to cisplatin resistance. Here, we examined the effects of DNA hypomethylating 5-azacitidine (5-aza) on two embryonal carcinoma cell lines (NCCIT, 2102Ep) and their cisplatin-resistant isogenic derivatives. Effects on cell viability and cisplatin sensitivity were assessed by the trypan blue exclusion method. Western blotting was used to examine induction of apoptosis 5-aza and results were validated by flow cytometry. Single agent treatment with 5-aza strongly impacted viability and induced apoptosis at low nanomolar concentrations, both in cisplatin-sensitive and -resistant cell lines. 5-aza exerted an immediate apoptotic response, followed by a prolonged inhibitory effect on cell viability and cell-cycle progression. Sequential treatment with 5-aza and cisplatin reduced cellular survival of the cisplatin-resistant sublines already at nanomolar concentrations, suggesting a partial restoration of cisplatin sensitivity by the compound. 5-aza demonstrated anti-tumor activity as a single agent at low nanomolar concentrations in GCT cells, irrespective of cisplatin-sensitivity. 5-aza may also have the potential at least to partially restore cisplatin-sensitivity in non-seminoma cells, supporting the hypothesis that combining DNA demethylating agents with cisplatin-based chemotherapy may be a valid therapeutic approach in patients with refractory GCTs.

Oing, C., P. Tennstedt, R. Simon, J. Volquardsen, K. Borgmann, C. Bokemeyer, C. Petersen, E. Dikomey, K. Rothkamm, and W. Y. Mansour, "BCL2-overexpressing prostate cancer cells rely on PARP1-dependent end-joining and are sensitive to combined PARP inhibitor and radiation therapy.", Cancer letters, vol. 423, pp. 60-70, 2018 06 01. Abstract

Here we report that BCL2 blocks DNA double strand break (DSB) repair via nonhomologous end-joining (NHEJ), through sequestration of KU80 protein outside the nucleus. We find that this effect is associated with a repair switch to the error-prone PARP1-dependent end-joining (PARP1-EJ). We present in-vitro proof-of-concept for therapeutic targeting of this switch using PARP inhibitor to specifically enhance the radiosensitivity of BCL2-overexpressing cells. Given its erroneous behavior, PARP1-EJ might allow for the accumulation of genetic alterations and tumor progression. Consistently, we report an inverse correlation between BCL2 expression and biochemical recurrence-free survival of 10.259 prostate cancer (PCa) patients who underwent primary radical-prostatectomy for localized disease. Further, we evaluated retrospectively the impact of BCL2 expression on clinical outcome of 1.426 PCa patients, who had been given salvage radiotherapy at relapse after radical prostatectomy. In line with its role in blocking NHEJ, BCL2 over-expressers showed significantly better response to salvage radiotherapy compared to low-expressers. Collectively, our findings identify BCL2 status in PCa as a putative predictor of (i) radiotherapy response and (ii) response to treatment with PARP inhibitor olaparib as a radiosensitizing agent.

Ojha, N. K., E. Nematian-Ardestani, S. Neugebauer, B. Borowski, D. Ahmed El-Hussein, P. Toshinori Hoshi, D. Enrico Leipold, and D. Stefan H Heinemann, "Sodium channels as gateable non-photonic sensors for membrane-delimited reactive species.", j.bbamem, vol. http://dx.doi.org/10.1016/j.bbamem.2014.01.031, 2014.
Okasha, E., M. Hussien, M. Abdou, and M. Koronfel, "Fodder beet, Beta vulgaris (L.) as affected by soil texture, compost quantity, diluted seawater and their interactions", Egyptian Journal of Applied Sciences, vol. 24, pp. 116–138, 2009. Abstract
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Okasha, H., S. Elkholy, M. Sayed, M. El-Sherbiny, R. El-Hussieny, E. El-Gemeie, W. Al-Nabawy, M. S. Mohamed, and Y. Elsherif, "Ultrasound, endoscopic ultrasound elastography, and the strain ratio in differentiating benign from malignant lymph nodes.", Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology, vol. 19, issue 1, pp. 7-15, 2018. Abstract

BACKGROUND AND STUDY AIMS: Endoscopic ultrasound elastography (EUS-elastography), or sono-elastography, has emerged in the past 2 decades as a qualitative method of estimating tissue stiffness. Strain elastography allows for semi-quantitative measurements of the average elasticity of a lesion, and previous studies have proposed the strain ratio (SR) for overcoming the limitations of the elasticity score. The main objective of this study is to assess the specificity, sensitivity and predictive values of the SR measured by EUS-elastography in differentiating benign from malignant lymph nodes (LNs). This study also aims to find significant ultrasonographic features other than the SR which could help in predicting LN malignancy.

PATIENTS AND METHODS: This prospective study included 126 Egyptian patients with lymphadenopathy. US and EUS-elastography and the SR were assessed, in addition to detailed sonographic features, including size, longest diameter, shortest diameter, ratio of shortest/longest diameter, echotexture (echogenic or echo-poor) and hilum (lost or preserved).

RESULTS: The SR cut-off value of 4.61 showed a sensitivity and specificity of 89.8% and 83.3%, respectively. This parameter had high positive and negative predictive values of 82.5% and 90.2%, respectively, for predicting malignant LNs. Univariate regression analysis showed that echogenicity, hilum preservation, elastography, the shortest dimension, the ratio of the shortest/longest dimension, ultrasound diagnosis and SR could be potential predictors of the final lymph node diagnosis. Sono-diagnosis depending on echogenicity, the shortest/longest diameter ratio and a preserved hilum in combination was the only predictive parameter in multivariate regression analysis.

CONCLUSION: EUS-elastography and the SR could be excellent prognostic indices in differentiating benign from malignant lymph nodes if combined with other US features.

Okasha, A., and C. Johnson, "Agent-based computational economics: Studying the effect of different levels of rationality on inflation and unemployment", 2009 IEEE Symposium on Computational Intelligence for Financial Engineering: IEEE, pp. 20–27, 2009. Abstract
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Okasha, T. M., W. Y. Mohamed, M. S. Ismail, and K. S. Anbar, Cerebral Oxygenation among Acute Traumatic Brain Injury Patients, , Germany, LAP LAMBERT, 2013. Cerebral Oxygenation among Acute Traumatic Brain Injury Patient
Okasha, H., S. Elkholy, M. Sayed, and R. E. Mahdy, "Endoscopic ultrasound and endoscopic ultrasound-guided fine needle aspiration in the diagnosis of diffuse gastrointestinal lesions with inconclusive endoscopic biopsies", Turkish journal of Gastroenterology, vol. 28, pp. 370-376, 2017.
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