This paper presents a numerical study of the performance of a dynamically loaded finite journal plastic bearing lubricated with a non-Newtonian fluid, taking into account the elastic deformation of the bearing. The non-Newtonian characteristics are adopted in this paper through an equivalent power-law. An expression for a modified Reynolds equation is derived in order to obtain the pressure gradient. Elastic deformation of the bearing surface was estimated in a direction normal to the bearing surface using Boussinesq equations. The film shape was modified accordingly and then iterated with the hydrodynamic pressure distribution in the bearing until a convergent solution was obtained. The Reynolds equation was solved numerically, considering three values of the flow-behavior index (n = 0.6, 1, and 1.2) and a wide range of journal speeds, materials, and clearance ratios. Consequently, the finite perturbation technique was used to determine the eight values of oil film stiffness and damping coefficients. By using the dynamic coefficients, the stability characteristics of the rotor-bearing system and the critical speed were calculated. The results show that increasing the flow-behavior index enhances the rotor-bearing system stability. A considerable destabilizing effect is obtained upon decreasing the elastic deformation coefficient.

AIM: Participants in an unorganized gathering are potential hosts of diseases, bringing diseases from around the world to be introduced to a large at-risk population. Therefore, we investigated the gene repertoire in 29 Escherichia coli strains linked to urinary tract infection isolated from patients transferred to the hospital after attending an unorganized gathering in Cairo.

MATERIALS & METHODS: Virulence and resistance determinants, phenotypic antibiotic resistance, biofilm formation, their serotypes and phylogenetic relationships were analyzed.

RESULTS: The 29 tested serovars were phenotypically virulent, with the prevalence of group B2, and resistant to tetracycline, naldixic acid, ampicillin, trimethoprim, neomycin, oxytetracycline and erythromycin encoding the iss virulent gene.

CONCLUSION: A One Health approach is a must to monitor and control E. coli urinary tract infections.

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The major limiting factor in long-term administration of doxorubicin is the development of cumulative dose-dependent cardiomyopathy and congestive heart failure that limit the use of this drug. The present study was undertaken to find out the chemo protective role of methimazole against doxorubicin-induced cardiotoxicity in experimental animals. In the present study, doxorubicin treatment in a dose of 3mg/kg, i.p., every other day for six doses showed a significant 2.6-, 3- and 10.5-fold increase in the cardiac enzyme activities CK-MB and LDH and troponin-I, respectively, in the serum of the animals. Histopathological investigation of heart tissues showed swollen muscle fibers with interstitial edema and inflammatory exudate. Pretreatment of the animals with methimazole at a dose level of 40 mg/kg, i.p., 30 min before doxorubicin, returned the cardiac enzyme levels to nearly normal value with partial reversal of the inflammatory lesions and the swollen muscle fibers induced by doxorubicin. Moreover, methimazole pretreatment, decreased the doxorubicin level in the heart tissues with a significant increase in plasma level and non significant effect on doxorubicin level in tumor cells. At the same time, methimazole pretreatment did not significantly interfere with the antitumor activity of doxorubicin.