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Gaafar, T., O. Osman, A. Osman, W. Attia, H. Hamza, and R. E. Hawary, ". Gene expression profiling of endometrial versus bone marrow derived MSCs : upregulation of cytokine genes", Mol Cell Biochem ; DOI 10.1007/s11010-014-2109-0, 2014. paper_published_in_molecular__cellular_biochemistry.pdf
Osman, K. M., M. I. El-Enbaawy, N. A. Ezzeldeen, and H. M. G. Hussein, ". A rapid screening identification of Clostridium perfringens alpha and epsilon toxins recovered from mastitic bovine milk by SDS-PAGE electrophoresis", OIE - World Organisation for Animal Health Scientific and Technical 2009 , vol. 28, pp. 975-986, 2009.
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M.Ali, N., N. G. El-Mawla, M. R. Hamza, H. Khalid, R. Gaafar, H. El-Zawahry, I. Osman, and M. M.Saber, "- Low dose interferon Alpha 2 in metastaic hypernephroma", International congress on cancer, Cairo International Conference City Center, Cairo International Conference Center, Nov. 7-10, 1994.
O.M., E., K. S.S.A, G. T.M, A. E. - A. N.M, and A. - E. A.M, "- Biochemical assessment of a novel fermentation products as antimicrobial antioxidant and anticancer ((In vitro study).", Bell. Fac. Agric., Cairo Univ., (DT12 Conference, Special issue)., vol. 66, issue 5, pp. 42-53, 2015.
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shimaa A.E.NASr, A. M.M, H. A, H. E, E. Agrab.H.M, Moubarak.S.T, and S. H. Z. and O.K, "): Sporicidal activity of some disinfectants against C.perfringens isolated from poultry broiler litter", . Alexandria Journal of Veterinary Sciences., vol. 42, pp. 30-37, 2014. sporicidal.pdf
O.E.Mohamed, M. M.Hady, and M.M.Zaki, ") Role of dietary zinc on immune response of broiler chickens", Veterinary Medical Journal, Giza, vol. 38, issue 2, pp. 283-295, 1990.
Osman, 1. K. M., M. I. Mohamed, A. M.Yousef, M. M. Aly, M. I. Radwan, and H. A. Alwathnani, ") Pathogenicity of Some Avian Salmonella Serovars in Two Different Animal Models: SPF Chickens and BALB/c Mice.", Environment and we , vol. 5, pp. 65-78., 2010. publications.doc
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El-Shabrawi, M. H., S. Omran, S. Wageeh, M. Isa, Sawsan Okasha, Mona Isa, N. A. Mohsen, O. Zekry, G. E-Bartan, and H. M. El-karaksy, "(99m)Technetium-macroaggregated albumin perfusion lung scan versus contrast enhanced echocardiography in the diagnosis of the hepatopulmonary syndrome in children with chronic liver disease.", European journal of gastroenterology & hepatology, vol. 22, issue 8, pp. 1006-12, 2010 Aug. Abstract

BACKGROUND AND AIMS: The hepatopulmonary syndrome (HPS) is a triad of advanced chronic liver disease (CLD), arterial hypoxemia and intrapulmonary arteriovenous shunting in the absence of a primary cardiopulmonary disease. HPS has been more frequently reported in adults than in children with no data on its prevalence in children with CLD. The aim of this study was to detect the prevalence of the HPS in a cohort of children with CLD because of chronic hepatitis B and/or C virus infection, schistosomiasis as well as inborn metabolic errors. We also aimed to evaluate the role of Technetium labeled macroaggregated albumin (Tc--MAA) perfusion lung scan versus contrast enhanced echocardiography (CEE) with intravenous injection of agitated saline in the diagnosis and quantification of intrapulmonary shunts and their relationship to important clinical and laboratory findings.

METHODS: Forty Egyptian children (22 males) were investigated. Their ages ranged from 5 to 12 years (with a mean of 9.5 years). Twenty individuals proved to have cirrhosis.

RESULTS: Blood gas determination revealed more significant arterial hypoxemia in cirrhotics than noncirrhotics both under room air and after breathing 100% oxygen for 15 mins. CEE showed comparable cardiac measurements in cirrhotic and noncirrhotic patients, and diagnosed intrapulmonary shunts in three hypoxemic cirrhotic patients; whereas Tc--MAAperfusion lung scan diagnosed shunts in seven patients (five of them cirrhotic). The presence of shunts was significantly correlated with the duration of CLD, clinical findings, presence of cirrhosis and porto-systemic collaterals. We calculated for each patient a shunt index (SI) by the formula: (activity outside thorax/activity outside plus inside thorax) 100; and an SI value of 0.278 was found to be a cutoff value for shunt detection. All patients with SI above this value had shunting associated with hypoxemia and all patients with SI below this value had no hypoxemia (specificity 100%).

CONCLUSION: Arterial hypoxemia and intrapulmonary shunts were diagnosed in 17.5% of this cohort of children with cirrhotic or noncirrhotic CLD representing the classic HPS. Tc--MAA perfusion lung scan was more sensitive than CEE in detection of intrapulmonary shunts. SI cutoff value of 0.278 was found to be highly specific for shunt detection and we recommend its validation in further studies.

Malik, S., H. Almusawa, S. Kumar, A. - M. Wazwaz, and M. S. Osman, "A (2+ 1)-dimensional Kadomtsev–Petviashvili equation with competing dispersion effect: Painlevé analysis, dynamical behavior and invariant solutions", Results in Physics, vol. 23: Elsevier, pp. 104043, 2021. Abstract
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Dixon, S. J., J. Bashutski, M. L. Rütz, H. A. Goldberg, S. M. Sims, A. Gramoun, S. Shorey, M. Manolson, J. N. Heersche, H. Zhang, et al., "The $\alpha$v$\beta$3 integrin as a therapeutic target for inhibition of bone resorption", Arthritis research & therapy, vol. 6, no. Suppl 3: BioMed Central Ltd, pp. 23, 2004. Abstract
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Wali IE, E. GEM, Omar WA, and E. R. S., " The Antimicrobial Efficacy of Ozonated Water, Chlorhexidine and Sodium Hypochlorite against Single Species Biofilms of Enterococcus faecalis and Candida albicans", Egyptian Journal of Medical Microbiology:, vol. 17, pp. 419-428., 2008.
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O. Moustafa, G., A. Kalmouch, M. Rdwan, O. M. M, and S. M, " Synthesis of novel 2, 3'-bipyrrole derivatives from chalcone and amino acids as antitumor agents..", EGYPTIAN JOURNAL OF CHEMISTRY, 2020.
Fahmy, M. M., K. Ashmawy, and H. M. Omar, " Studies on the pupation period of the nasal bot fly of Camel (Cephalopina titillator Clark, 1797 ) in Egypt", J. Egypt. Vet. Med. Ass., vol. 45, issue 1, pp. 311-317, 1985.
Omar, H. M., M. Nisreen Ezz El-Dien, and M. M. Fahmy, " Short communication: Cryptosporidiosis in African ostrich (Struthio camelus). ", Assuit Vet. Med. J. , vol. 40 , issue 79, pp. 250-253., 1998.
Omran, S. M. S. E. - G. N. R. A. • S. • D., Sherif A. Mazen • Salwa S. El-Gamal • Nagy Ramadan D. Omran, , 2000.
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Manal, A. A. E., A. M. Mahmoud, and M. A. Olfat, " Role of stress-inducing corticosteroid on the development of parasitosis in Orechromis niloticus ", J. Egypt. Vet. Med. Ass., vol. 63, no.4, pp. 133-153, 2003.
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El-Beltagi, H. S., A. E. - M. M. R. Afify, S. A. M. El-Salam, and A. A. Omran, " Protein solubility, digestibility and fractionation after germination of sorghum varieties.", PLoS ONE , vol. 7, issue 2, pp. e31154, 2012.
Khedr, A., Omar, H., Soliman, Metwalli, M., Ebiary, E., J. El-Jakkee, and M. Refai, " Protective efficacy of plasmid DNA vaccine coding omph gene of Pasteurella multocida. ", Proc. 2d Intern. Conf. Vet. Res. Div. NRC, Cairo, Egypt , vol. 1, pp. 97-118., 2005. protective_efficiency_of_plasmid_DNA_vacc.pdf
S.B.Mahmoud, M.K.Anwar, O.G.Shaker, and D.A.ElSharkawy, " Possible Relation between Vitamin D and Interleukin-17 in the Pathogenesis of Lichen Planus.", Dermatology, vol. 237, issue 6, pp. 896-901, 2021.
Abdallah A. Hassanin, A. Osman, Osama Osman Atallah, Mohamed T. El-Saadony, Sameh A. Abdelnour, Heba S. A. Taha, Mohamed F. Awad, H. Elkashef, Ahmed Ezzat Ahmed, I. Abdel-Rahim, et al., " Phylogenetic comparative analysis: Chemical and biological features of caseins (alpha-S-1, alpha-S-2, beta and kappa-) in domestic dairy animal", Frontiers in Veterinary Science, vol. 9, pp. 952319, 2022.
Hussein, K., A. Hasanin, S. Mostafa, and G. Obaya, " PERIOPERATIVE COMPLICATIONS OF LAPAROSCOPIC SLEEVE GASTRECTOMY: A SINGLE CENTer EGYPTIAN EXPERIENCE. ", critical care medecine, vol. 43, issue 12, pp. 298, 1975 Sep, 2015. Abstract

It has been established that H+ secretion can be maintained in frog stomach in the absence of exogenous CO2 by using a nutrient bathing fluid containing 25 mM H2PO4 (pH approximately equal to 4.5) or by lowering the pH of a nonbuffered nutrient solution to about 3.0-3.6. Exogenous CO2 in the presence of these nutrient solutions uniformly caused a marked decrease in H+ secretion, PD, adn short-circuit current (Isc) and an increase in transmucosal resistance (R). Elevation of nutrient [k+] to 83 mM reduced R significantly but transiently without change in H+ when nutrient pH less than 5.0, whereas R returned to base line and H+ increased when nutrient pH greater than 5.0. Acidification of the nutrient medium in the presence of exogenous CO2 results in inhibition of the secretory pump, probably by decreasing intracellular pH, and also interferes with conductance at the nutrient membrane. Removal of exogenous CO2 from standard bicarbonate nutrient solution reduced by 50% the H+, PD, and Isc without change in R; K+-free nutrient solutions reverse these changes in Isc and PD but not in H+. The dropping PD and rising R induced by K+-free nutrient solutions in 5% CO2 - 95% O2 are returned toward normal by 100% O2. Our findings support an important role for exogenous CO2 in maintaining normal acid-base balance in frog mucosa by acting as an acidifying agent.

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