Publications

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Journal Article
Fadeel, D. A. A., M. Fadel, A. Tawfik, and Y. Omar, "Transfersomal eosin topical delivery assisted by fractional CO2 laser for photodynamic treatment of palmar hyperhidrosis: case study", Drug Delivery and Translational Research, 2022. AbstractWebsite
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Fadeel, D.A., fadel, Tawfik, A., and Y. Omar, "Transfersomal eosin topical delivery assisted by fractional CO2 laser for photodynamic treatment of palmar hyperhidrosis: case study", Drug Delivery and Translational Research, , vol. 12 , issue (12), , pp. 3000-3006, 2023.
Fadeel, D.A., fadel, Tawfik, A., and Y. Omar, "Transfersomal eosin topical delivery assisted by fractional CO2 laser for photodynamic treatment of palmar hyperhidrosis: case study", Drug Delivery and Translational Research, , vol. 12, issue 12, pp. 3000-3006, 2022.
Soliman, M. H., H. S. Omar, M. A. El-Awady, S. Al-Assal, and G. A. Y. El-Din, "Transformation and expression of Na+/H+antiporter vacuolar (AtNHX1) gene in tobacco plants under salt stress", Arab J Biotech, vol. 12, pp. 99-108, 2009.
Soliman, M. H., H. S. Omar, M. A. El-Awady, S. Al-Assal, and A. A. G. Y. El-Din, "Transformation and expression of Na+/H+antiporter vacuolar (AtNHX1) gene in tobacco plants under salt stress.", Arab J. Biotech.,, vol. 12, issue 1, pp. 99-108, 2008. Abstract
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OG, S., and Sadik NA, "Transforming growth factor beta 1 and monocyte chemoattractant protein-1 as prognostic markers of diabetic nephropathy.", Hum Exp Toxicol., vol. 1089-96., issue 10, pp. 32, 2013.
H, S., B. O, A. A, M. N, and A. O, "Transforming growth factor-β1 in children with diabetic nephropathy", Pediatric Nephrology, vol. 34, issue 1, pp. 81-85, 2019.
Mokhtar, G., A. Adly, A. Abdel Baky, D. Ezzat, G. Abdel Hakeem, H. Hassab, I. Youssry, I. Ragab, I. Florez, L. M. Sherief, et al., "Transfusion of blood components in pediatric age groups: an evidence-based clinical practice guideline adapted for the use in Egypt using ‘Adapted ADAPTE’", Annals of Hematology: Springer, 2024. Abstract
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Mokhtar, G., A. Adly, A. Abdel Baky, D. Ezzat, G. Abdel Hakeem, H. Hassab, I. Youssry, I. Ragab, I. Florez, L. M. Sherief, et al., "Transfusion of blood components in pediatric age groups: an evidence-based clinical practice guideline adapted for the use in Egypt using ‘Adapted ADAPTE’", Annals of Hematology: Springer, 2024. Abstract
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Yosry, A., R. F. Omar, M. E. Al Arab, H. Abdel-Hafez, M. Gohar, and G. Esmat, "Transient Elastography Can Predict the Risk of Hepatocellular Carcinoma in Patients with Chronic Hepatitis C", HEPATOLOGY, vol. 56, no. 1}, Meeting Abstract = {1385, pp. 844A, OCT, 2012. Abstract
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Shen, F., C. - X. Wu, Y. Yao, P. Peng, Z. - Y. Qin, Y. Wang, Y. Zheng, L. - F. Zhou, N. Gohar, M. Shehata, et al., "Transition over 35 Years in the Incidence Rates of Primary Central Nervous System Tumors in Shanghai, China and Histological Subtyping Based on a Single Center Experience Spanning 60 Years", Asian Pacific Journal of Cancer Prevention, vol. 14, no. 12, pp. 7385–7393, 2013. Abstract
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Hekim, N., Y. Coşkun, A. Sınav, A. H. Abou-Zeid, M. Ağırbaşlı, S. O. Akintola, Ş. Aynacıoğlu, M. Bayram, N. L. Bragazzi, C. Dandara, et al., "Translating Biotechnology to Knowledge-Based Innovation, Peace, and Development? Deploy a Science Peace Corps—An Open Letter to World Leaders", Omics: a journal of integrative biology, vol. 18, no. 7: Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA, pp. 415–420, 2014. Abstract
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Ahmed, M. A., N. Okasha, and M. Gabal, "Transport and magnetic properties of Co-Zn-La ferrite", Materials Chemistry and Physics, vol. 83, issue 1, pp. 107 - 113, 2004. AbstractWebsite

The dielectric constant (ε′) and dielectric loss factor (ε″) for the ferrite Co1-xZnxLa yFe2-yO4; 0.1≤x≤1.0 were measured at different frequencies (100kHz to 5MHz) and different temperatures (300-850K). More than one type of polarization participates in the dielectric process, Maxwell Wagner polarization is the one participating in the high temperature region. The electrical conductivity measurement showed that there is more than one conduction mechanism participating in conductivity. The hopping mechanism either by holes or electrons or both is the predominant one. The increase in conductivity is due to the thermally activated mobility and not to thermal creation of additional mobile charge carriers. The replacement of Fe 3+ by La on octahedral sites and the presence of Co2+ as well as Zn2+ ions on the tetrahedral sites play a significant role in the electrical and magnetic properties behavior of the investigates samples. The values of the activation energy obtained indicate the semi-conducting behavior of the investigated ferrite. © 2003 Published by Elsevier B.V.

Othman, A. A., S. A. Syed, A. H. Newman, and N. D. Eddington, "Transport, metabolism, and in vivo population pharmacokinetics of the chloro benztropine analogs, a class of compounds extensively evaluated in animal models of drug abuse.", The Journal of pharmacology and experimental therapeutics, vol. 320, issue 1, pp. 344-53, 2007 Jan. AbstractWebsite

Recently, extensive behavioral research has been conducted on the benztropine (BZT) analogs with the goal of developing successful therapeutics for cocaine abuse. The present study was conducted to characterize the contribution of dispositional factors in mediating the behavioral differences among the chloro BZT analogs and to identify cytochrome P450 enzymes involved in their metabolism. Bidirectional transport and efflux studies of four of the chloro BZT analogs were conducted. Screening with a panel of human and rat Supersomes was performed for 4',4''-diCl BZT. In addition, pharmacokinetic and brain distribution studies for 4'-Cl and 4',4''-diCl BZT in Sprague-Dawley rats were conducted. The permeability of the chloro analogs ranged from 8.26 to 32.23 and from 1.37 to 21.65 x 10(-6) cm/s, whereas the efflux ratios ranged from 2.1 to 6.9 and from 3.3 to 28.4 across Madin-Darby canine kidney-multidrug resistance 1 (MDCK-MDR1) and Caco-2 monolayers, respectively. The P-glycoprotein (P-gp) inhibitor verapamil reduced the efflux ratios and enhanced the absorptive transport of the chloro BZT analogs. 4',4''-diCl BZT was a substrate of human CYP2D6 and 2C19 and rat 2C11 and 3A1. The brain uptake for 4'-Cl and 4',4''-diCl BZT was comparable and higher than previously reported for cocaine (brain-to-plasma partition coefficient = 4.6-4.7 versus 2.1 for cocaine). The rank order for t(1/2) was 4',4''-diCl BZT > 4'-Cl BZT > cocaine and for steady-state volume of distribution was 4'-Cl BZT > 4',4''-diCl BZT > cocaine. In conclusion, the chloro analogs differ significantly in their clearance and duration of action, which correlates to their behavioral profiles and abuse liability. Furthermore, these results suggest that the distinctive behavioral profile of these analogs is not due to limited brain exposure.

A.L.Aboul-Nasr, H.Hamza, Z.Abou-El-Maaty, H. Gaber, and O.Azzam, "Transvaginal ultrasound appearance of the ovary in infertile women with oligomenorrhea: association with clinical and endocrine profiles. ", Middle East Fertil. Soc. J, vol. 9, issue 2, pp. 140-149, 2004.
Osman, M. S., H. Rezazadeh, and M. Eslami, "Traveling wave solutions for (3+1) dimensional conformable fractional Zakharov-Kuznetsov equation with power law nonlinearity", Nonlinear Engineering, vol. 8, issue 1, pp. 559–567, 2019.
Srivastava, H. M., D. Baleanu, J. T. Machado, M. S. Osman, R. Rezazadeh, S. Arshed, and H. Günerhan, "Traveling wave solutions to nonlinear directional couplers by modified Kudryashov method", Physica Scripta, vol. 95, issue 7, pp. 075217, 2020.
Idriss, N. K., H. G. Sayyed, A. Osama, and D. Sabry, "Treatment Efficiency of Different Routes of Bone Marrow-Derived Mesenchymal Stem Cell Injection in Rat Liver Fibrosis Model.", Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, vol. 48, issue 5, pp. 2161-2171, 2018 Aug 16. Abstract

BACKGROUND/AIMS: The most appropriate route for bone marrow-derived mesenchymal stem cell (BM-MSC) transplantation in the management of liver fibrosis remains controversial. This study investigated the therapeutic efficacy of intravenous and intrasplenic BM-MSC transplantation on carbon tetrachloride (CCl4)-induced rat liver fibrosis.

METHODS: Fifty rats were divided into 5 groups (n = 10 rats per group): healthy control group, CCl4 group, CCl4/ recovery group, CCl4/BM-MSC intravenous group, and CCl4/BM-MSC intrasplenic group. BM-MSCs were isolated, labeled with green fluorescent protein (GFP), and injected into fibrotic rats either intravenously or intrasplenically. Gene expression of interleukins (IL-1β and IL-6), interferon (INF)-γ, hepatic growth factor, and the hepatocyte-specific marker cytokeratin 18 was estimated by quantitative real-time reverse transcription-polymerase chain reaction. Vascular endothelial growth factor and connective tissue growth factor was detected by western blot analysis and enzyme-linked immunosorbent assay, respectively. At 2 weeks after intravenous and intrasplenic BM-MSC injections, GFP-positive cells were detected in liver tissue.

RESULTS: Both routes achieved a similar enhancement of liver function, which was confirmed by histopathological examination. The intravenous route was more effective than the intrasplenic route in reducing gene expression levels of IL-1β, IL-6, and INF-γ. However, fibrotic changes were still observed in the recovery group.

CONCLUSION: Intravenous BM-MSC injection was an efficient and appropriate route for BM-MSC transplantation for the management of liver fibrosis.

El-Haddad, M., M. El-Sebaie, R. Ahmad, E. Khalil, M. Shahin, R. Pant, M. Memon, A. Al-Hebshi, Y. Khafaga, M. Al-Shabanah, et al., "Treatment of aggressive fibromatosis: the experience of a single institution", Clinical Oncology, vol. 21, no. 10: Elsevier, pp. 775–780, 2009. Abstract
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Wiersma, S. T., B. McMahon, J. M. Pawlotsky, C. L. Thio, M. Thursz, S. G. Lim, P. Ocama, G. Esmat, M. Mendy, D. Bell, et al., "Treatment of chronic hepatitis B virus infection in resource-constrained settings: expert panel consensus (vol 31, pg 755, 2011)", LIVER INTERNATIONAL, vol. 32, no. 1, pp. 174, JAN, 2012. Abstract
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OA, A., B. DA, E. L. - H. MS, E. M. ZM, S. RM, and E. L. - M. MS, "Treatment of hypertrophic scars and keloids by fractional carbon dioxide laser: a clinical, histological, and immunohistochemical study.", Lasers Med Sci., vol. 24, 2015.
O.A., H., M. R.R., K. M.T.H.A., M. E.A., and N. N.A., "Treatment of industrial wastewater containing copper and lead ions using new carboxymethyl chitosan-activated carbon derivatives", Egyptian Journal of Chemistry, vol. 65(2), pp. pp. 123–132, 2022. ejchem_volume_65_issue_2_pages_123-132.pdf
Omar, M. T. A., A. A. - E. L. - G. Ebid, and A. M. E. Morsy, "Treatment of Post-Mastectomy lymphedema with Laser therapy Double Blind Placebo Controlled Randomized Study", Journal of Surgical Research, vol. 165, issue 1, pp. 82–90, 2011. CU-PDF.pdf
Hashem, M. Y., I. I. ISMAIL, and E. E. Omar, "Treatment of the cowpea weevil Callosobruchus maculatus F.(Bruchidae: Coleoptera) with low oxygen atmospheres containing carbon dioxide", Zeitschrift fuer Pflanzenkrankheiten und Pflanzenschutz, vol. 101, 1994. Abstract
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