Publications

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Journal Article
Othman, A. A., and M. S. Abdelazim, "Ventilator-associated pneumonia in adult intensive care unit prevalence and complications", The Egyptian Journal of Critical Care Medicine, vol. 6, 2017. vap_paper.pdf
Othman, A. A., and M. S. Abdelazim, "Ventilator-associated pneumonia in adult intensive care unit prevalence and complications", The Egyptian Journal of Critical Care Medicine, vol. 5, issue 2, pp. 61-63, 2017. vap_paper.pdf
Ertekin, E., I. M. van Hagen, A. M. Salam, R. Titia P.E, M. R. Johnson, J. Popelova, W. A. Parsonage, Z. Ashour, A. Shotan, J. M. Oliver, et al., "Ventricular tachyarrhythmia during pregnancy in women with heart disease, Data from ROPAC, a registry from the European Society of Cardiology", Int. J. Cardiol, vol. Oct, issue 220, pp. 131-136, 2016.
Yassa, M. M., H. A. Hassan, and F. A. Omara, "Virtual Business Collaboration Conceptual Knowledge Model (VBCKM", International Journal of Cloud Computing and Services Science (IJ-CLOSER), vol. 1, issue 3, pp. 148~154, 2012.
Yassa, M. M., F. A. Omara, and H. A. Hassan, "Virtual Business Collaboration Conceptual Knowledge Model (VBCKM)", International Journal of Cloud Computing and Services Science (IJ-CLOSER), vol. 1, issue 3, pp. 148-154, 2012. Abstract
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Yassa, M. M., F. A. Omara, and H. A. Hassan, "Virtual Business Collaboration Conceptual Knowledge Model (VBCKM)", International Journal of Cloud Computing and Services Science (IJ-CLOSER), vol. 1, issue 3, pp. 148-154, 2012.
Nabih, H. I., A. M. A. Omar, and R. M. Habib, "Visbreaking of a Heavy Gas Oil Fraction Promoted by Phenol Formaldehyde Sulphonate Polymer", Afinidad, IQS, vol. 60, issue 505, 2003.
Osman, T., and H. Arafa, "Viscous pumps: Comparative assessment of effectiveness", ARCHIVE Proceedings of the Institution of Mechanical Engineers Part J Journal of Engineering Tribology 1994-1996 (vols 208-210), vol. 217, issue 2, pp. 167-174, 2003.
TM, M., S. OG, E. - S. MM, and A. - N. ZM., "Visfatin -948G/T and resistin -420C/G polymorphisms in Egyptian type 2 diabetic patients with and without cardiovascular diseases.", Genome, vol. 57, issue 5, pp. 259-66. , 2014.
Karim, S. A., A. Mohamed, M. M. Abdel-Mottaleb, T. A. Osman, and A. Khattab, Visible light photocatalytic activity of PAN-CNTs/ZnO-NH2 electrospun nanofibers, , vol. 772, pp. 650 - 655, 2019. AbstractWebsite
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Karim, S. A., A. Mohamed, M. M. Abdel-Mottaleb, T. A. Osman, and A. Khattab, Visible light photocatalytic activity of PAN-CNTs/ZnO-NH2 electrospun nanofibers, , vol. 772, pp. 650 - 655, 2019. AbstractWebsite
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Mohamed, A., T. A. Osman, M. S. Toprak, M. Muhammed, E. Yilmaz, and A. Uheida, Visible light photocatalytic reduction of Cr(VI) by surface modified CNT/titanium dioxide composites nanofibers, , vol. 424, pp. 45 - 53, 2016/12/1/. AbstractWebsite

AbstractIn this work we report a highly efficient photocatalytic reduction of Cr(VI) based on PAN-CNT/TiO2-NH2 composite nanofibers fabricated by using electrospinning technique followed by chemical crosslinking of surface modified TiO2 NPs functionalized with amino group. The structure and morphology of the fabricated composite nanofibers were characterized by FTIR, SEM, TEM, TGA, and XPS. The results indicate that the composite nanofibers possess excellent photoreduction performance for Cr(VI) under visible light (125 W) after 30 min, which is much faster than previous reports. The effects of various experimental parameters such as catalyst dose, irradiation time, initial concentration of Cr(VI), and pH on the photoreduction efficiency of Cr(VI) were investigated. The highest photoreduction efficiency of Cr (VI) was obtained at low acidity and low amount of TiO2/CNT photocatalyst. The kinetic experimental data was attained and fitted well with a pseudo-first-order model. The UV–vis spectrophotometer and XPS analyses proved that chromate Cr(VI) was reduced to Cr(III). In addition, it can be concluded that the addition of the phenol enhances the photocatalytic reduction of Cr(VI). Furthermore, the photoreduction mechanism has also been discussed. Finally, the fabricated composite nanofibers were found to be stable after at least five regeneration cycles.

Mohammed, B. M., B. J. Fisher, D. Kraskauskas, D. Farkas, D. F. Brophy, R. Natarajan, and others, "Vitamin C: a novel regulator of neutrophil extracellular trap formation", Nutrients, vol. 5, no. 8: Multidisciplinary Digital Publishing Institute, pp. 3131–3150, 2013. Abstract
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Shahin, W. A. K., D. H. E. D. Hamed, R. A. K. Mahmoud, M. M. El-Falaki, and others, "Vitamin D and its binding protein in children with cystic fibrosis: A single center study", Egyptian Pediatric Association Gazette, vol. 64, no. 3: Elsevier, pp. 131–135, 2016. Abstract
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Shaheen, I. A., R. Aboukhalil, N. Abulata, Rasha Abdel-Raouf, B. Meligy, and Omnia Abdel-Dayem, "Vitamin D Insufficiency is Not Associated With Pediatric and Adolescent Immune Thrombocytopenia A Study in Conjunction With its Receptor Genetic Polymorphisms", Pediatric Hematology / Oncology , vol. 43, issue 3, pp. 1-4, 2021.
Shaheen, I. I. A., R. Aboukhalill, N. Abulata, Rasha Abdel-Raouf, B. Meligy, and Omnia Abdel-Dayem, "Vitamin D Insufficiency is Not Associated With Pediatric and Adolescent Immune Thrombocytopenia: A Study in Conjunction With its Receptor Genetic Polymorphisms", J Pediatr Hematol Oncol  , vol. 43, issue 1, pp. e1-e5, 2021.
Shaheen, I. A. M., R. Aboukhalil, N. Abulata, Rasha Abdel-Raouf, B. Meligy, and Omnia Abdel-Dayem, "Vitamin D Insufficiency is Not Associated With Pediatric and Adolescent Immune Thrombocytopenia: A Study in Conjunction With its Receptor Genetic Polymorphisms.", Journal of pediatric hematology/oncology, vol. 43, issue 1, pp. e1-e6, 2021. Abstract

Idiopathic thrombocytopenic purpura (ITP) is a heterogeneous immunologic disorder. Vitamin D has immune-modulatory effects. The pleiotropic effects of vitamin D are exerted via vitamin D receptor (VDR) and its genetic alterations could influence its functions. In our study, we measured the serum 25-hydroxyvitamin D levels in 98 Pediatric and Adolescent ITP patients, in addition to 100 apparently healthy controls. Genetic polymorphisms of the VDR gene FokI, BsmI, ApaI, and TaqI were tested using specific restriction enzymes for each polymorphism. Vitamin D deficiency in the studied Pediatric age was a dominant factor, but it was found not to be associated with Pediatric ITP. However, patients carrying the FokI CC genotype had statistically higher vitamin D levels compared with those carrying other genotypes (P=0.036). Patients who were carriers of the BsmI G allele had a nearly 2-fold higher risk of ITP (odds ratio: 2.203; 95% confidence interval: 1.467-3.309). Therefore, the BsmI polymorphism of VDR could be considered a molecular risk factor for ITP.

Ibrahim, M., H. Ogaly, and A. A. Khalaf, "Vitamin E attenuates neurotoxicity induced by deltamethrin in rats", BMC complementary and alternative medicine , vol. 14, issue 1, pp. 458, 2014. my_paper_dm_ve.pdf
Mona K Galal, Abdel Azim A Khalaf, H. A. Ogaly, and Marwa A Ibrahim, "Vitamin E attenuates neurotoxicity induced by deltamethrin in rats.", BMC complementary and alternative medicine, vol. 14, pp. 458, 2014 Dec 02. Abstract

BACKGROUND: The safety of Deltamethrin (DM) has been raised as a point of concern. The current investigation was envisaged to explore the responsiveness of oxidative stress parameters, DNA fragmentation and expression levels of TP53, cycloxygenase 2 (COX2) and cytochrome p4502E1 (CYP2E1) as toxicological endpoint in rats treated with DM. as well as attention was provided to the neuroprotective effect of vitamin E (VE).

METHODS: Four different groups of rats were used in this study, group I served as control, group II received DM (0.6 mg/kg BW), group III received both DM plus VE and finally group IV received VE only (200 mg/kg BW). The treatment regimen was extending for one month for all groups and the brain tissues were collected for further analysis.

RESULTS: The obtained results showed a highly statistically significant increase in lipid peroxidation (LPO) content, nitric oxide concentration, and DNA fragmentation percentage and expression level of CYP2E1, TP53 and COX2 genes, in addition statistical significant reduction in total antioxidant capacity in DM treated group as compared to control were detected. Oral administration of VE attenuated the neurotoxic effects of DM through improvement of oxidative status, DNA fragmentation percentage and suppressing the expression level of CYP2E1, TP53 and COX2 genes.

CONCLUSION: From this study we concluded that VE supplementation has beneficial impacts on DM neurotoxicity in rats through its antioxidant and antiapoptotic properties.

Mona K Galal, Abdel Azim A Khalaf, H. A. Ogaly, and Marwa A Ibrahim, "Vitamin E attenuates neurotoxicity induced bydeltamethrin in rats", BMC Complementary and Alternative Medicine, vol. 14, pp. 458-464, 2014. vit E_against_DM neurotoxicity.pdf
Oguntimein, B., T. S. El-Alfy, and M. A. Elsohly, "Volatile oils of Zanthoxylum rigidifolium and Zanthoxylum gilletii", Fitoterapia, 1985. Abstract
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Wolff, D., F. Stieler, G. Welzel, F. Lorenz, Y. Abo-Madyan, S. Mai, C. Herskind, M. Polednik, V. Steil, F. Wenz, et al., "Volumetric modulated arc therapy (VMAT) vs. serial tomotherapy, step-and-shoot IMRT and 3D-conformal RT for treatment of prostate cancer", Radiotherapy and Oncology, vol. 93, no. 2: Elsevier, pp. 226–233, 2009. AbstractWebsite

Introduction

Volumetric modulated arc therapy (VMAT), a complex treatment strategy for intensity-modulated radiation therapy, may increase treatment efficiency and has recently been established clinically. This analysis compares VMAT against established IMRT and 3D-conformal radiation therapy (3D-CRT) delivery techniques.
Methods

Based on CT datasets of 9 patients treated for prostate cancer step-and-shoot IMRT, serial tomotherapy (MIMiC), 3D-CRT and VMAT were compared with regard to plan quality and treatment efficiency. Two VMAT approaches (one rotation (VMAT1x) and one rotation plus a second 200° rotation (VMAT2x)) were calculated for the plan comparison. Plan quality was assessed by calculating homogeneity and conformity index (HI and CI), dose to normal tissue (non-target) and D95% (dose encompassing 95% of the target volume). For plan efficiency evaluation, treatment time and number of monitor units (MU) were considered.
Results

For MIMiC/IMRTMLC/VMAT2x/VMAT1x/3D-CRT, mean CI was 1.5/1.23/1.45/1.51/1.46 and HI was 1.19/1.1/1.09/1.11/1.04. For a prescribed dose of 76 Gy, mean doses to organs-at-risk (OAR) were 50.69 Gy/53.99 Gy/60.29 Gy/61.59 Gy/66.33 Gy for the anterior half of the rectum and 31.85 Gy/34.89 Gy/38.75 Gy/38.57 Gy/55.43 Gy for the posterior rectum. Volumes of non-target normal tissue receiving ⩾70% of prescribed dose (53 Gy) were 337 ml/284 ml/482 ml/505 ml/414 ml, for ⩾ 50% (38 Gy) 869 ml/933 ml/1155 ml/1231 ml/1993 ml and for ⩾ 30% (23 Gy) 2819 ml/3414 ml/3340 ml/3438 ml /3061 ml. D95% was 69.79 Gy/70.51 Gy/71,7 Gy/71.59 Gy/73.42 Gy. Mean treatment time was 12 min/6 min/3.7 min/1.8 min/2.5 min.
Conclusion

All approaches yield treatment plans of improved quality when compared to 3D-conformal treatments, with serial tomotherapy providing best OAR sparing and VMAT being the most efficient treatment option in our comparison. Plans which were calculated with 3D-CRT provided good target coverage but resulted in higher dose to the rectum.
Keywords

Volumetric modulated arc therapy (VMAT);
Intensity-modulated radiotherapy (IMRT);
Sequential tomotherapy;
Prostate cancern/a

Osman, T., E. Kenawy, K. I. Abdrabo, D. Shaw, A. Alshamndy, M. Elsharif, M. Salem, M. Alwetaishi, R. M. Aly, and B. Elboshy, "Voluntary Local Review Framework to Monitor and Evaluate the Progress towards Achieving Sustainable Development Goals at a City Level: Buraidah City, KSA and SDG11 as A Case Study", Sustainability, vol. 13, no. 17: Multidisciplinary Digital Publishing Institute, pp. 9555, 2021. Abstract
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Ahmed, H. H., O. M. Osman, H. M. Youssef, N. A. A. AlTaweel, and M. Saleh, "Von Willebrand Factor Propetide as a marker of disease activity in Systemic Sclerosis: Correlation with Clinical, Radiological and Biochemical parameters", The Egyptian Rheumatologist , vol. 25, issue 1, 2003.
EL-ASSALY, M. D., and others, "VRT in Traumatic Maxillo-Facial Injuries; Is it of an Added Value Compared to Axial and Reconstructed CT Images?", The Medical Journal of Cairo University, vol. 88, no. March: The Clinical Society of Cairo University, pp. 405–411, 2020. Abstract
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