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Shaheen, I. A., R. Aboukhalil, N. Abulata, Rasha Abdel-Raouf, B. Meligy, and Omnia Abdel-Dayem, "Vitamin D Insufficiency is Not Associated With Pediatric and Adolescent Immune Thrombocytopenia A Study in Conjunction With its Receptor Genetic Polymorphisms", Pediatric Hematology / Oncology , vol. 43, issue 3, pp. 1-4, 2021.
Shaheen, I. I. A., R. Aboukhalill, N. Abulata, Rasha Abdel-Raouf, B. Meligy, and Omnia Abdel-Dayem, "Vitamin D Insufficiency is Not Associated With Pediatric and Adolescent Immune Thrombocytopenia: A Study in Conjunction With its Receptor Genetic Polymorphisms", J Pediatr Hematol Oncol  , vol. 43, issue 1, pp. e1-e5, 2021.
Shaheen, I. A. M., R. Aboukhalil, N. Abulata, Rasha Abdel-Raouf, B. Meligy, and Omnia Abdel-Dayem, "Vitamin D Insufficiency is Not Associated With Pediatric and Adolescent Immune Thrombocytopenia: A Study in Conjunction With its Receptor Genetic Polymorphisms.", Journal of pediatric hematology/oncology, vol. 43, issue 1, pp. e1-e6, 2021. Abstract

Idiopathic thrombocytopenic purpura (ITP) is a heterogeneous immunologic disorder. Vitamin D has immune-modulatory effects. The pleiotropic effects of vitamin D are exerted via vitamin D receptor (VDR) and its genetic alterations could influence its functions. In our study, we measured the serum 25-hydroxyvitamin D levels in 98 Pediatric and Adolescent ITP patients, in addition to 100 apparently healthy controls. Genetic polymorphisms of the VDR gene FokI, BsmI, ApaI, and TaqI were tested using specific restriction enzymes for each polymorphism. Vitamin D deficiency in the studied Pediatric age was a dominant factor, but it was found not to be associated with Pediatric ITP. However, patients carrying the FokI CC genotype had statistically higher vitamin D levels compared with those carrying other genotypes (P=0.036). Patients who were carriers of the BsmI G allele had a nearly 2-fold higher risk of ITP (odds ratio: 2.203; 95% confidence interval: 1.467-3.309). Therefore, the BsmI polymorphism of VDR could be considered a molecular risk factor for ITP.

Ibrahim, M., H. Ogaly, and A. A. Khalaf, "Vitamin E attenuates neurotoxicity induced by deltamethrin in rats", BMC complementary and alternative medicine , vol. 14, issue 1, pp. 458, 2014. my_paper_dm_ve.pdf
Mona K Galal, Abdel Azim A Khalaf, H. A. Ogaly, and Marwa A Ibrahim, "Vitamin E attenuates neurotoxicity induced by deltamethrin in rats.", BMC complementary and alternative medicine, vol. 14, pp. 458, 2014 Dec 02. Abstract

BACKGROUND: The safety of Deltamethrin (DM) has been raised as a point of concern. The current investigation was envisaged to explore the responsiveness of oxidative stress parameters, DNA fragmentation and expression levels of TP53, cycloxygenase 2 (COX2) and cytochrome p4502E1 (CYP2E1) as toxicological endpoint in rats treated with DM. as well as attention was provided to the neuroprotective effect of vitamin E (VE).

METHODS: Four different groups of rats were used in this study, group I served as control, group II received DM (0.6 mg/kg BW), group III received both DM plus VE and finally group IV received VE only (200 mg/kg BW). The treatment regimen was extending for one month for all groups and the brain tissues were collected for further analysis.

RESULTS: The obtained results showed a highly statistically significant increase in lipid peroxidation (LPO) content, nitric oxide concentration, and DNA fragmentation percentage and expression level of CYP2E1, TP53 and COX2 genes, in addition statistical significant reduction in total antioxidant capacity in DM treated group as compared to control were detected. Oral administration of VE attenuated the neurotoxic effects of DM through improvement of oxidative status, DNA fragmentation percentage and suppressing the expression level of CYP2E1, TP53 and COX2 genes.

CONCLUSION: From this study we concluded that VE supplementation has beneficial impacts on DM neurotoxicity in rats through its antioxidant and antiapoptotic properties.

Mona K Galal, Abdel Azim A Khalaf, H. A. Ogaly, and Marwa A Ibrahim, "Vitamin E attenuates neurotoxicity induced bydeltamethrin in rats", BMC Complementary and Alternative Medicine, vol. 14, pp. 458-464, 2014. vit E_against_DM neurotoxicity.pdf
Oguntimein, B., T. S. El-Alfy, and M. A. Elsohly, "Volatile oils of Zanthoxylum rigidifolium and Zanthoxylum gilletii", Fitoterapia, 1985. Abstract
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Moftah, H. M., N. Ghali, A. E. Hassanien, M. A. Ismail, and others, "Volume identification and estimation of MRI brain tumor", Hybrid Intelligent Systems (HIS), 2012 12th International Conference on: IEEE, pp. 120–124, 2012. Abstract
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Wolff, D., F. Stieler, G. Welzel, F. Lorenz, Y. Abo-Madyan, S. Mai, C. Herskind, M. Polednik, V. Steil, F. Wenz, et al., "Volumetric modulated arc therapy (VMAT) vs. serial tomotherapy, step-and-shoot IMRT and 3D-conformal RT for treatment of prostate cancer", Radiotherapy and Oncology, vol. 93, no. 2: Elsevier, pp. 226–233, 2009. AbstractWebsite

Introduction

Volumetric modulated arc therapy (VMAT), a complex treatment strategy for intensity-modulated radiation therapy, may increase treatment efficiency and has recently been established clinically. This analysis compares VMAT against established IMRT and 3D-conformal radiation therapy (3D-CRT) delivery techniques.
Methods

Based on CT datasets of 9 patients treated for prostate cancer step-and-shoot IMRT, serial tomotherapy (MIMiC), 3D-CRT and VMAT were compared with regard to plan quality and treatment efficiency. Two VMAT approaches (one rotation (VMAT1x) and one rotation plus a second 200° rotation (VMAT2x)) were calculated for the plan comparison. Plan quality was assessed by calculating homogeneity and conformity index (HI and CI), dose to normal tissue (non-target) and D95% (dose encompassing 95% of the target volume). For plan efficiency evaluation, treatment time and number of monitor units (MU) were considered.
Results

For MIMiC/IMRTMLC/VMAT2x/VMAT1x/3D-CRT, mean CI was 1.5/1.23/1.45/1.51/1.46 and HI was 1.19/1.1/1.09/1.11/1.04. For a prescribed dose of 76 Gy, mean doses to organs-at-risk (OAR) were 50.69 Gy/53.99 Gy/60.29 Gy/61.59 Gy/66.33 Gy for the anterior half of the rectum and 31.85 Gy/34.89 Gy/38.75 Gy/38.57 Gy/55.43 Gy for the posterior rectum. Volumes of non-target normal tissue receiving ⩾70% of prescribed dose (53 Gy) were 337 ml/284 ml/482 ml/505 ml/414 ml, for ⩾ 50% (38 Gy) 869 ml/933 ml/1155 ml/1231 ml/1993 ml and for ⩾ 30% (23 Gy) 2819 ml/3414 ml/3340 ml/3438 ml /3061 ml. D95% was 69.79 Gy/70.51 Gy/71,7 Gy/71.59 Gy/73.42 Gy. Mean treatment time was 12 min/6 min/3.7 min/1.8 min/2.5 min.
Conclusion

All approaches yield treatment plans of improved quality when compared to 3D-conformal treatments, with serial tomotherapy providing best OAR sparing and VMAT being the most efficient treatment option in our comparison. Plans which were calculated with 3D-CRT provided good target coverage but resulted in higher dose to the rectum.
Keywords

Volumetric modulated arc therapy (VMAT);
Intensity-modulated radiotherapy (IMRT);
Sequential tomotherapy;
Prostate cancern/a

Osman, T., E. Kenawy, K. I. Abdrabo, D. Shaw, A. Alshamndy, M. Elsharif, M. Salem, M. Alwetaishi, R. M. Aly, and B. Elboshy, "Voluntary Local Review Framework to Monitor and Evaluate the Progress towards Achieving Sustainable Development Goals at a City Level: Buraidah City, KSA and SDG11 as A Case Study", Sustainability, vol. 13, no. 17: Multidisciplinary Digital Publishing Institute, pp. 9555, 2021. Abstract
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Ahmed, H. H., O. M. Osman, H. M. Youssef, N. A. A. AlTaweel, and M. Saleh, "Von Willebrand Factor Propetide as a marker of disease activity in Systemic Sclerosis: Correlation with Clinical, Radiological and Biochemical parameters", The Egyptian Rheumatologist , vol. 25, issue 1, 2003.
EL-ASSALY, M. D., and others, "VRT in Traumatic Maxillo-Facial Injuries; Is it of an Added Value Compared to Axial and Reconstructed CT Images?", The Medical Journal of Cairo University, vol. 88, no. March: The Clinical Society of Cairo University, pp. 405–411, 2020. Abstract
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Saliou, Y., S. Abbagari, A. Houwe, M. S. Osman, D. S. Yamigno, K. T. Crépin, and M. Inc, "W-shape bright and several other solutions to the (3+ 1)-dimensional nonlinear evolution equations", Modern Physics Letters B, vol. 35, issue 30: World Scientific, pp. 2150468, 2021. Abstract
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El-Shazly, M. M., E. Elzayat, W. A. Omar, I. I. A. El-Sebeay, Y. A. Edmardash, M. M. Soliman, K. M. Abdel Rahman, and M. S. Ibrahim, "Water cytotoxicity and dioxins bioaccumulation in an Egyptian delta wetland ecosystem", African Journal of Aquatic Science, vol. 41, issue 3, pp. 289-296, 2016. khaled05.pdf
El-Shazly, M. M., E. Elzayat, W. A. Omar, I. I. A. El-Sebeay, Y. A. Edmardash, M. M. Soliman, K. M. Abdel Rahman, and M. S. Ibrahim, "Water cytotoxicity and dioxins bioaccumulation in an Egyptian delta wetland ecosystem", African Journal of Aquatic Science, vol. 41, issue 3: Taylor & Francis, pp. 289-296, 2016. Abstract
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El-Shazly, M. M., E. M. I. Elzayat, W. A. Omar, I. I. A. El-Sebeay, Y. A. Edmardash, M. M. Soliman, K. M. Abdel Rahman, and M. S. Ibrahim, "Water cytotoxicity and dioxins bioaccumulation in an Egyptian Delta wetland ecosystem", African Journal of Aquatic Science, vol. 41, issue 3, pp. 289-296, 2016.
El-Shazly, M. M., E. Elzayat, W. A. Omar, and M. M. S. K. M. A. R. M. S. I. & IIA El-Sebeay, YA Edmardash, "Water cytotoxicity and dioxins bioaccumulation in an Egyptian delta wetland ecosystem", African Journal of Aquatic Science , vol. 41, issue 3, pp. 289-296, 2016. AbstractWebsite

Manzala Lake, as one of the main Egyptian wetland ecosystems, is facing risks of pollution. An in vitro cytotoxicity
test using a mammalian cell line was employed to determine the toxicity of multiple pollutants in the water and
Tilapia zillii fish sampled from the lake. The concentrations of seven polychlorinated dibenzo-p-dioxins and ten
polychlorinated dibenzofurans were investigated in water and muscle of the fish in 2014. Cytotoxicity testing
showed that the percentage inhibition of cell viability in the studied sites ranged between 56.16% and 83.22%.
Dioxin analysis indicated that the average concentrations of 1,2,3,4,6,7,8,9-octachlorodibenzo-p-dioxin,
1,2,3,4,7,8-hexachlorodibenzofuran, 1,2,3,4,6,7,8-heptachlorodibenzofuran and 1,2,3,4,6,7,8,9-octachlorodibenzofuran
were higher than the toxic equivalence quotients (TEQs) set by the World Health Organization (WHO) in all water
and fish muscle samples; however, the average concentration of 2,3,7,8-tetrachlorodibenzofuran was higher only
in fish muscle samples. The bioaccumulation factor (BAF) ranged dramatically between 2 and 58.5 for the detected
dioxins. Adverse human health effects through the consumption of fish are not expected, because dioxin levels in
fish muscle are deemed safe for human consumption. Implementation of a strategic multidisciplinary action plan is
strongly recommended to sustain this delta wetland ecosystem.

Soliman, M. M., A. E. Hassanien, and H. M. Onsi, "Watermarking 3D Triangular Mesh Models Using Intelligent Vertex Selection", Proceedings of the Second International Afro-European Conference for Industrial Advancement AECIA 2015: Springer International Publishing, pp. 617–627, 2016. Abstract
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Hamad, M. E. S., A. S. A. Mohamed, and M. I. Owis, Wavelet Analysis of Instantaneous Heart Rate to Discriminate Diabetic Patients, , 2006. Abstract
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Kumar, S., R. Kumar, M. S. Osman, and B. Samet, "A wavelet based numerical scheme for fractional order SEIR epidemic of measles by using Genocchi polynomials", Numerical Methods for Partial Differential Equations, vol. 37, pp. 1250–1268, 2021.
Mona M. Soliman, A. A. Aboul Ella Hassanien, and H. M. Onsi, "The Way of Improving PSO Performance: Medical Imaging Watermarking Case Study", , A Joint Conference of the 8th International Conference on Rough Sets and Current Trends in Computing (RSCTC 2012) , Chengdu, China, pp. 237-242, 2012.
Soliman, M. M., A. E. Hassanien, and H. M. Onsi, "The way of improving PSO performance: medical imaging watermarking case study", International Conference on Rough Sets and Current Trends in Computing: Springer Berlin Heidelberg, pp. 237–242, 2012. Abstract
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Soliman, M. M., A. E. Hassanien, and H. M. Onsi, "The way of improving PSO performance: medical imaging watermarking case study", International Conference on Rough Sets and Current Trends in Computing: Springer Berlin Heidelberg, pp. 237–242, 2012. Abstract
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Soliman, M. M., A. E. Hassanien, and H. M. Onsi, "The way of improving PSO performance: medical imaging watermarking case study", International Conference on Rough Sets and Current Trends in Computing: Springer Berlin Heidelberg, pp. 237–242, 2012. Abstract
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Elkhadem, A., and N. Orabi, "Weak evidence suggests higher risk for bracket bonding failure with self-etch primer compared to conventional acid etch over 12 months.", Evidence-based dentistry, vol. 14, issue 2, pp. 52-3, 2013. Abstract

DATA SOURCES: Medline, Embase, Cochrane Oral Health Group's Trials Register and the Cochrane Central Register of Controlled Trials (CENTRAL). Unpublished data were sought by searching ClinicalTrials.gov, the National Research Register and Pro-Quest Dissertation Abstracts and Thesis database. There were no language restrictions.

STUDY SELECTION: Randomised and controlled clinical trials (including split mouth) directly comparing self-etch and acid-etch primers including patients with full-arch, fixed and bonded orthodontic appliances (not banded) with follow-up periods of at least 12 months were included.

DATA EXTRACTION AND SYNTHESIS: Two authors abstracted data independently, with disagreements being resolved by a third. The Cochrane Risk of Bias tool was used to assess study quality. A random effects meta-analysis was undertaken.

RESULTS: Eleven studies were included in the qualitative summary with five studies contributing to a meta-analysis. These five studies (n =3444 brackets, 1721 acid-etch, 1723 self-etch) had relatively low statistical and clinical heterogeneity. Meta-analysis demonstrated a tendency for a higher risk of failure (odds ratio 1.35; 95% CI, 0.99-1.83; P 5 0.06) with self-etch primers. The use of self-etch techniques was also associated with a small but statistically significant time saving (weighted mean difference 23.2 seconds per bracket; 95% CI, 20.7-25.8; P \0.001). There was insufficient evidence to assess the effect of bonding modality on demineralisation rates.

CONCLUSIONS: There is weak evidence indicating higher odds of failure with self-etch primer than acid-etch over 12 months in orthodontic patients, and there is strong evidence that a self-etch primer is likely to result in modest time savings (eight minutes for full bonding) compared with acid-etch.

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