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Conference Paper
Osman, N. O., D. E. E. Faheem, W. A. El-Sherief, H. H. Abdel-Aal, and S. Alsirafy, "Olanzapine for anorexia in cancer cachexia patients: A placebo-controlled randomized trial", ESMO Congress 2022, Paris, 10 September, 2022. Abstract

Background: Cancer-associated cachexia (CAC) is a complex multifactorial syndrome. Various antipsychotics have been associated with weight gain, especially olanzapine (OLZ) which is suggested to have a role in the management of CAC. It remains unclear whether OLZ has an ameliorating effect on cancer patients’ anorexia, even when those patients exhibit no nausea or vomiting. Given the potential effect of OLZ on CAC and the mixed findings regarding this subject, the current trial aims at evaluating the efficacy of OLZ as a monotherapy in incurable cancer patients with cancer cachexia-associated anorexia.

Trial design: This is a single institution double-blind placebo-controlled randomized clinical trial. One hundred and sixty-four patients are being recruited from December 2021. The trial includes adult patients with incurable solid tumor, CAC, loss of appetite (≥4 score on the 0 to 10 loss of appetite scale of the Edmonton Symptom Assessment System [ESAS]), Eastern Cooperative Oncology Group (ECOG) performance status of 0-2 and a predicted survival >3 months. Causes for exclusion are: highly emetogenic chemotherapy, antipsychotic or appetite stimulant administration, nausea or vomiting score >3 on the 0 to 10 scale of the ESAS, weight gain for a known cause (e.g., oedema) or central nervous system disease. Participants will be 1:1 randomized to the intervention arm (OLZ 5 mg tablet once a night for 28 days) or the control arm (placebo tablet once at night for 28 days). The primary endpoint is the change in the loss of appetite score on the 0 to 10 scale of the ESAS from day 0 to day 7 of treatment. The secondary endpoints include the change in loss of appetite score from day 0 to days 14, 21 and 28 and the change in quality of life, handgrip strength, body mass index, body weight, lean body mass, fatigue and c-reactive protein level from day 0 to day 28.

Clinical trial identification: NCT05243251.

Ouannas, A., A. T. Azar, and A. G. Radwan, "On inverse problem of generalized synchronization between different dimensional integer-order and fractional-order chaotic systems", Microelectronics (ICM), 2016 28th International Conference on: IEEE, pp. 193–196, 2016. Abstract
Ouannas, A., A. T. Azar, and A. G. Radwan, "On inverse problem of generalized synchronization between different dimensional integer-order and fractional-order chaotic systems", Microelectronics (ICM), 2016 28th International Conference on: IEEE, pp. 193–196, 2016. Abstract
Omar, H. A., W. Zhuang, and L. Li, "On Multihop Communications For In-Vehicle {Internet} Access Based On a TDMA MAC Protocol", Proc. IEEE International Conference on Computer Communications (INFOCOM), Apr., 2014. Abstract


Khalil, E. E., and A. F. Omran, "On the Modeling of Flow regimes in Heavy Truck Passengers Cabins", Energy and Propulsion , AIAA-2014-3760, July 2014, USA, July , 2014.
Omran, A. F., and E. E. Khalil, "On the Modelling of Thermal Comfort in Heavy Truck Passengers Cabins", , Proceedings AIAA Science and Technology Forum and Exposition 2015, paper AIAA_2015_1441, Orlando, January, 2015.
Osman, H., A. Emira, A. N. Mohieldin, M. Abouzied, and A. Soliman, "On-chip high-Q bandpass filtering using N-phase current driven passive mixers", European Conference on Circuit Theory and Design (ECCTD), Linköping, Sweden, August, 2011.
Magdy Ahmed, M., Maged Georgy, and H. Osman, "Ontology-based investigation of construction delay analysis methodologies in Egypt", Construction Research Congress 2014: Construction in a Global Network, pp. 1428–1437, 2014. Abstract
Owis, M. I., "Open-Source Implementation of Medical Databases", 3rd Cairo International Biomedical Engineering Conference, CIBEC 2006, 2006. Abstract
Herskovits, E. H., C. Davatzikos, and M. I. Owis, "Open-Source Reimplementation of a Brain-Image Database", NIH Tenth Annual Human Brain Project Conference, Washington, DC, April 26th - 27th 2004., 2004. Abstract
Khalil, E. E., M. Shitta, and E. Ogedengbe, "Optimal Bonding Temperature for Wafering of Mimosa pudica-Based Solar Cell", IECEC, paper AIAA-2013-3740, July 2013., USA, July , 2013.
Osman, Z., T. Sharaf, E. L. M. Shibini, and A. M. Hussein, "Optimal Power Flow Solutions at Different Load Levels, ¬Application to Egyptian Power System", First Symposium on Electric Power Systems in Fast Developing Countries, KSA, March 1987.
Hegazy, S., J. El-Azab, Y. Badr, and S. Obaya, "Optimal Ultra-wide Spatial-Spectral Windows for Hyperentangled Two-photon Emission ", MET A’16 The 7 th International Conference on Metamaterials, Photonic Crystals and Plasmonics, Malaga - Spain, 25 July 2016.
Fathy, M., A. I. Omran, and W. A. Badway, "Optimizing the fabrication parameters for high performance αFe2O3 anti-reflection coating", THE XXXI INTERNATIONAL CONFERENCE ON “Materials Science and Applications, Hughada, Egypt, 6 - 9 January , 2015.
El-Bahnasawy, R. A. K., I. A. El-Azab, and H. M. Onsi, "Optimizing Web-based Virtual Reality Models", 10th International Conference on Intelligent Systems Design and Applications, SDA’10, 2010 IEEE, Cairo, pp. 990-994, Cairo University Conference Center, 29 November, 2010. Abstract

Optimizing the virtual reality model is a necessity to cope with the nature of the World Wide Web. Virtual reality scenes should load within an acceptable time for the user’s experience and the sense of being immersed in the virtual environment is not to be affected. In this study, we propose to optimize web-based virtual reality models by removing redundant objects within the scenes, while keeping the model readable to webauthors and modelers. The achieved reductions in the model file size and in the model parsing time
were further reduced by introducing structure and appearance tolerance.

El-Dib, A., H. Youssef, E. - M. Metwally, and Z. Osman, "Optimum VAR Sizing and Allocation Using Particle Sward Optimization", Power Engineering Society General Meeting, USA, June, 2006.
Okebiorun, M. O., and S. H. ElGohary, "Optothermal response and Tissue Damage analysis during Laser Hair Removal", Journal of Physics: Conference Series, vol. 1472, no. 1: IOP Publishing, pp. 012003, 2020. Abstract
Fatayer, T. S., S. Khattab, and F. A. Omara, "OverCovert: Using Stack-Overflow Software Vulnerability to Create a Covert Channel", New Technologies, Mobility and Security (NTMS), 2011 4th IFIP International Conference on: IEEE, pp. 1–5, 2011. Abstract
Mohamed, L. Z., W. A. Ghanem, O. A. El Kady, M. Lotfy, H. A. Ahmed, F. A. Elrefaie, and others, "Oxidation characteristics of porous nickel low-chromium binary alloys in air at 1273K for 100 h", Key Engineering Materials, vol. 786: Trans Tech Publ, pp. 37–43, 2018. Abstract
Abd-Ellah, M., A. Abdelaziz, E. Ali, S. Abdelaziz, A. Sayed, M. I. Owis, and A. Eldeib, "Parallel Generation of Digitally Reconstructed Radiographs on Heterogeneous Multi-GPU Workstations", 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS) , Florida, USA., 2016.
Ellah, M. A., A. Alaa, E. Ali, S. Abdelaziz, A. Sayed, M. I. Owis, and A. Eldeib, "Parallel generation of digitally reconstructed radiographs on heterogeneous multi-GPU workstations", 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC): IEEE, pp. 3953–3956, 2016. Abstract


Opara, K. R., A. A. Hadi, and A. W. Mohamed, "Parametrized Benchmarking: An Outline of the Idea and a Feasibility Study", Proceedings of the 2020 Genetic and Evolutionary Computation Conference Companion, New York, NY, USA, Association for Computing Machinery, pp. 197–198, 2020. Abstract

Performance of real-parameter global optimization algorithms is typically evaluated using sets of test problems. We propose a new methodology of extending these benchmarks to obtain a more balanced experimental design. This can be done by selectively removing some of the transformations originally used in the definitions of the test problems such as rotation, scaling, or translation. In this way, we obtain several variants of each problem parametrized by interpretable, high-level characteristics. These binary parameters are used as predictors in a multiple regression model explaining the algorithmic performance. Linear models allow for the attribution of strength and direction of performance changes to particular characteristics of the optimization problems and thus provide insight into the underlying mechanics of the investigated algorithms. The proposed ideas are illustrated with an application example showing the feasibility of the new benchmark. Parametrized benchmarking is a step towards obtaining multi-faceted insight into algorithmic performance and the optimization problems. The overall goal is to systematize a method of matching problems to algorithms and in this way constructively address the limitations imposed by the no free lunch theorem.

Abd-Ellatif, S. S., A. H. Osman, and A. A. Elfiky, "Pathological studies on Safety and efficacy of bee venom and propolis on CCL4-induced hepatotoxicity in rats", Program of the 4-th. German Congress, Expo and Intensive Course on apitherapy and Apipuncture with international Participation, 4 April, 2006.
Elmiligi, H., A. Morgan, W. M. El-Kharashi, F. Gebali, and others, "Performance Analysis of Networks-on-Chip Routers", Design and Test Workshop, 2007. IDT 2007. 2nd International: IEEE, pp. 232–236, 2007. Abstract
Mansour, A. M., E. W. Huang, Z. Zhong, and others, "Performance evaluation of articulated multi-body floaters in harsh environment", The Eighteenth International Offshore and Polar Engineering Conference: International Society of Offshore and Polar Engineers, 2008. Abstract