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2021
Jan, M. U., A. Xin, H. U. Rehman, M. A. Abdelbaky, S. Iqbal, and M. Aurangzeb, "Frequency Regulation of an Isolated Microgrid With Electric Vehicles and Energy Storage System Integration Using Adaptive and Model Predictive Controllers", IEEE Access, vol. 9, pp. 14958-14970, 2021.
Aboshady, H. M., N. Mandonnet, A. M. Johansson, E. Jonas, and J. - C. Bambou, "Genomic variants from RNA-seq for goats resistant or susceptible to gastrointestinal nematode infection.", PloS one, vol. 16, issue 3, pp. e0248405, 2021. Abstract

Gastrointestinal nematodes (GIN) are an important constraint in small ruminant production. Genetic selection for resistant animals is a potential sustainable control strategy. Advances in molecular genetics have led to the identification of several molecular genetic markers associated with genes affecting economic relevant traits. In this study, the variants in the genome of Creole goats resistant or susceptible to GIN were discovered from RNA-sequencing. We identified SNPs, insertions and deletions that distinguish the two genotypes, resistant and susceptible and we characterized these variants through functional analysis. The T cell receptor signalling pathway was one of the top significant pathways that distinguish the resistant from the susceptible genotype with 78% of the genes involved in this pathway showing genomic variants. These genomic variants are expected to provide useful resources especially for molecular breeding for GIN resistance in goats.

Sivarajan, S., S. A. Mani, J. John, M. S. M. Fayed, Y. - A. Kook, and M. C. Wey, "The global distribution of permanent canine hypodontia: A systematic review", Korean Journal of Orthodontics, vol. 51, issue 1, pp. 55-74, 2021. the_global_distribution_of_permanent_canine_hypodontia-_a_systematic_review.pdf
Agarwal, A., R. Finelli, M. K. P. Selvam, K. Leisegang, A. Majzoub, N. Tadros, E. Ko, N. Parekh, R. Henkel, D. Durairajanayagam, et al., "A Global Survey of Reproductive Specialists to Determine the Clinical Utility of Oxidative Stress Testing and Antioxidant Use in Male Infertility.", The world journal of men's health, vol. 39, issue 3, pp. 470-488, 2021. Abstract

PURPOSE: The use of antioxidants is common practice in the management of infertile patients. However, there are no established guidelines by professional societies on antioxidant use for male infertility.

MATERIALS AND METHODS: Using an online survey, this study aimed to evaluate the practice pattern of reproductive specialists to determine the clinical utility of oxidative stress (OS) testing and antioxidant prescriptions to treat male infertility.

RESULTS: Responses from 1,327 participants representing 6 continents, showed the largest participant representation being from Asia (46.8%). The majority of participants were attending physicians (59.6%), with 61.3% having more than 10 years of experience in the field of male infertility. Approximately two-thirds of clinicians (65.7%) participated in this survey did not order any diagnostic tests for OS. Sperm DNA fragmentation was the most common infertility test beyond a semen analysis that was prescribed to study oxidative stress-related dysfunctions (53.4%). OS was mainly tested in the presence of lifestyle risk factors (24.6%) or sperm abnormalities (16.3%). Interestingly, antioxidants were prescribed by 85.6% of clinicians, for a duration of 3 (43.7%) or 3-6 months (38.6%). A large variety of antioxidants and dietary supplements were prescribed, and scientific evidence were mostly considered to be modest to support their clinical use. Results were not influenced by the physician's age, geographic origin, experience or training in male infertility.

CONCLUSIONS: This study is the largest online survey performed to date on this topic and demonstrates 1) a worldwide understanding of the importance of this therapeutic option, and 2) a widely prevalent use of antioxidants to treat male infertility. Finally, the necessity of evidence-based clinical practice guidelines from professional societies is highlighted.

Jabborova, D., S. Wirth, M. Halwani, M. F. M. Ibrahim, I. E. H. Azab, M. M. El-Mogy, and A. Elkelish, "Growth Response of Ginger (Zingiber officinale), Its Physiological Properties and Soil Enzyme Activities after Biochar Application under Greenhouse Conditions", Horticulturae, vol. 7, issue 8: Multidisciplinary Digital Publishing Institute, pp. 250, 2021. Abstract
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Sapena, V., M. Enea, F. Torres, C. Celsa, J. Rios, G. E. M. Rizzo, P. Nahon, Z. Mariño, R. Tateishi, T. Minami, et al., "Hepatocellular carcinoma recurrence after direct-acting antiviral therapy: an individual patient data meta-analysis.", Gut, 2021. Abstract

OBJECTIVE: The benefit of direct-acting antivirals (DAAs) against HCV following successful treatment of hepatocellular carcinoma (HCC) remains controversial. This meta-analysis of individual patient data assessed HCC recurrence risk following DAA administration.

DESIGN: We pooled the data of 977 consecutive patients from 21 studies of HCV-related cirrhosis and HCC, who achieved complete radiological response after surgical/locoregional treatments and received DAAs (DAA group). Recurrence or death risk was expressed as HCC recurrence or death per 100 person-years (100PY). Propensity score-matched patients from the ITA.LI.CA. cohort (n=328) served as DAA-unexposed controls (no-DAA group). Risk factors for HCC recurrence were identified using random-effects Poisson.

RESULTS: Recurrence rate and death risk per 100PY in DAA-treated patients were 20 (95% CI 13.9 to 29.8, I=74.6%) and 5.7 (2.5 to 15.3, I=54.3), respectively. Predictive factors for recurrence were alpha-fetoprotein logarithm (relative risk (RR)=1.11, 95% CI 1.03 to 1.19; p=0.01, per 1 log of ng/mL), HCC recurrence history pre-DAA initiation (RR=1.11, 95% CI 1.07 to 1.16; p<0.001), performance status (2 vs 0, RR=4.35, 95% CI 1.54 to 11.11; 2 vs 1, RR=3.7, 95% CI 1.3 to 11.11; p=0.01) and tumour burden pre-HCC treatment (multifocal vs solitary nodule, RR=1.75, 95% CI 1.25 to 2.43; p<0.001). No significant difference was observed in RR between the DAA-exposed and DAA-unexposed groups in propensity score-matched patients (RR=0.64, 95% CI 0.37 to 1.1; p=0.1).

CONCLUSION: Effects of DAA exposure on HCC recurrence risk remain inconclusive. Active clinical and radiological follow-up of patients with HCC after HCV eradication with DAA is justified.

Salminen, J., I. Kaate, A. M. S. Kamel, S. - G. Jung, and B. J. Jansen, "How Does Personification Impact Ad Performance and Empathy? An Experiment with Online Advertising", International Journal of Human-Computer Interaction, vol. 37, no. 2: Bellwether Publishing, Ltd., pp. 141-155, 2021. AbstractWebsite

This research explores the value of personas for supporting professional advertisers to design adverts for social media. We test if a personified user group (PUG), when provided to online ad designers, results in better ad performance than when using a non-personified user group (NUG) that had no face picture or name. Our experiment has 30 participants that created Facebook ads using both PUG and NUG. We found that using PUG did increase advertising click performance of ads created by people who are more experienced with ads and personas. Moreover, an analysis of the ad texts showed that the use of PUG increased the empathy of the created ads, supporting the foundational empathy benefit cited in HCI literature. However, the use of PUG did not significantly increase purchase intent. The results imply that using PUG for online ad design evokes more empathy and improves click-through performance. More empathetic ads can have a positive impact on social media users, given that they appear to increase relevance. © 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.

Park, J. - G., F. S. Oladunni, M. A. Rohaim, J. Whittingham-Dowd, J. Tollitt, M. D. J. Hodges, N. Fathallah, M. B. Assas, W. Alhazmi, A. Almilaibary, et al., "Immunogenicity and protective efficacy of an intranasal live-attenuated vaccine against SARS-CoV-2.", iScience, vol. 24, issue 9, pp. 102941, 2021. Abstract

Global deployment of an effective and safe vaccine is necessary to curtail the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we evaluated a Newcastle disease virus (NDV)-based vectored-vaccine in mice and hamsters for its immunogenicity, safety, and protective efficacy against SARS-CoV-2. Intranasal administration of recombinant (r)NDV-S vaccine expressing spike (S) protein of SARS-CoV-2 to mice induced high levels of SARS-CoV-2-specific neutralizing immunoglobulin A (IgA) and IgG2a antibodies and T-cell-mediated immunity. Hamsters immunized with two doses of vaccine showed complete protection from lung infection, inflammation, and pathological lesions following SARS-CoV-2 challenge. Importantly, administration of two doses of intranasal rNDV-S vaccine significantly reduced the SARS-CoV-2 shedding in nasal turbinate and lungs in hamsters. Collectively, intranasal vaccination has the potential to control infection at the site of inoculation, which should prevent both clinical disease and virus transmission to halt the spread of the COVID-19 pandemic.

Mansour, Y. A., E. - S. M. M. Mosallam, S. Hussein, E. M. M. Elleithy,, Jouini R, A. S. Mubarak, T. M. Dawoud, R. A. Alsubki, Jwaher H. Alhaji, Hassan A. Hemeg, et al., Immunolocalization of androgen and vitamin D receptors in the epididymis of mature ram (Ovis aries), , 2021.
Ahmed M. El Kenawy, Juan I. Lopez-Moreno, Matthew F. McCabe, Fernando Domínguez-Castro, Dhais Pe˜na-Angulo, Islam M. Gaber, Abduldaem S. Alqasemi, Khalifa M. Al Kindi, T. Al-Awadhi, Mohammed E. Hereher, et al., "The impact of COVID-19 lockdowns on surface urban heat island changes and air-quality improvements across 21 major cities in the Middle East", Environmental Pollution, vol. 288, pp. 1-13, 2021.
Ahmed M. El Kenawy, Juan I. Lopez-Moreno, Matthew F. McCabe, Fernando Domínguez-Castro, Dhais Pe˜na-Angulo, Islam M. Gaber, Abduldaem S. Alqasemi, Khalifa M. Al Kindi, T. Al-Awadhi, Mohammed E. Hereher, et al., "The impact of COVID-19 lockdowns on surface urban heat island changes and air-quality improvements across 21 major cities in the Middle East", Environmental Pollution, vol. 288, pp. 1-13, 2021.
Ahmed M. El Kenawy, Juan I. Lopez-Moreno, Matthew F. McCabe, Fernando Domínguez-Castro, Dhais Pe˜na-Angulo, Islam M. Gaber, Abduldaem S. Alqasemi, Khalifa M. Al Kindi, T. Al-Awadhi, Mohammed E. Hereher, et al., "The impact of COVID-19 lockdowns on surface urban heat island changes and air-quality improvements across 21 major cities in the Middle East", Environmental Pollution, vol. 288, pp. 1-13, 2021.
El-Nokrashy, A. M., R. A. El-Banna, B. M. Edrise, M. M. Abdel-Rahim, M. Jover-Cerda, A. Tomas-Vidal, A. Prince, S. J. Davies, E. R. El-Haroun, and A. M. A. - S. Goda, "Impact of nucleotide enriched diets on the production of gilthead seabream, Sparus aurata fingerlings by modulation of liver mitochondrial enzyme activitity, antioxidant status, immune gene expression, and gut microbial ecology", Aquaculture, vol. 535, issue 736398, 2021. aquaculture.pdf
Selim, S., W. Abuelsoud, S. S. Alsharari, B. F. Alowaiesh, M. M. Al-Sanea, S. A. Jaouni, M. M. Y. Madany, and H. AbdElgawad, "Improved Mineral Acquisition, Sugars Metabolism and Redox Status after Mycorrhizal Inoculation Are the Basis for Tolerance to Vanadium Stress in C3 and C4 Grasses", Journal of Fungi, vol. 7, no. 11, 2021. AbstractWebsite

Vanadium (V) can be beneficial or toxic to plant growth and the interaction between arbuscular mycorrhizal fungi (AMF) and V stress was rarely investigated at physiological and biochemical levels of plant groups (C3 and C4) and organs (roots and shoots). We tested the potential of AMF to alleviate the negative effects of V (350 mg V/Kg soil) on shoots and roots of rye and sorghum. Relative to sorghum (C4), rye (C3) showed higher levels of V and lower levels of key elements under V stress conditions. V inhibited growth, photosynthesis, and induced photorespiration (increased HDR & GO activities) and oxidative damage in both plants. AMF colonization reduced V stress by differently mitigating the oxidative stress in rye and sorghum. This mitigation was accompanied with increases in acid and alkaline phosphatase activities in plant roots and increased organic acids and polyphenols exudation into the soil, thus reduced V accumulation (29% and 58% in rye and sorghum shoot, respectively) and improved absorption of mineral nutrients including Ca, Mg and P. AMF colonization improved photosynthesis and increased the sugar accumulation and metabolism. Sugars also acted as a supplier of C skeletons for producing of antioxidants metabolite such as ascorbate. At the antioxidant level, rye was more responsive to the mitigating impact of AMF. Higher antioxidants and detoxification defence system (MTC, GST, phenolics, tocopherols and activities of CAT, SOD and POX) was recorded for rye, while sorghum (C4) improved its GR activity. The C3/C4-specificity was supported by principal component analysis. Together, this study provided both fundamental and applied insights into practical strategies to mitigate the phytotoxicity hazards of V in C3 and C4 grasses. Moreover, our results emphasize the importance of AMF as an environment-friendly factor to alleviate stress effects on plants and to improve growth and yield of unstressed plants.

S.Almuhayawi, M., A. H.A.Hassan, S. K. A. Jaouni, D. H. M. Alkhalifah, W. N.Hozzein, S. Selim, H. AbdElgawad, and G. Khamis, "Influence of elevated CO2 on nutritive value and health-promoting prospective of three genotypes of Alfalfa sprouts (Medicago Sativa)", Food Chemistry, 2021.
Giraud, F., W. H. Kassab, E. Robert, E. Jaillard, J. E. Spangenberg, M. Masrour, M. S. Hammed, M. F. Aly, and K. El Hariri, "Integrated stratigraphy of the latest Barremian–early Albian interval in the western part of the Tethyan margin: new data from the Essaouira-Agadir Basin (Western Morocco)", Newsletters on Stratigraphy, vol. 54, issue 1, pp. 43-78, 2021.
Giraud, F., W. H. Kassab, E. Robert, E. Jaillard, J. E. Spangenberg, M. Masrour, M. S. Hammed, M. F. Aly, and K. El Hariri, "Integrated stratigraphy of the latest Barremian–early Albian interval in the western part of the Tethyan margin: new data from the Essaouira-Agadir Basin (Western Morocco)", Newsletters on Stratigraphy, vol. 54, issue 1, pp. 43-78, 2021.
Errichetti, E., B. S. Ankad, A. K. Jha, S. Sonthalia, B. N. Akay, R. Bakos, Y. J. Bhat, M. Bosseila, R. Braun, H. Cabo, et al., "International Dermoscopy Society criteria for non-neoplastic dermatoses (general dermatology): validation for skin of color through a Delphi expert consensus.", International journal of dermatology, 2021. Abstract

BACKGROUND: The International Dermoscopy Society (IDS) recently released a set of five basic dermoscopic parameters (vessels, scales, follicular findings, "other structures," and specific clues) encompassing a total of 31 subitems to standardize the use of dermoscopy in non-neoplastic dermatoses, yet they have been developed taking into account Caucasian/Asian skin, with consequent possible limitations if used in dark skin.

OBJECTIVES: To validate the abovementioned criteria for the use in dark-skinned patients (phototypes IV-VI) through an expert consensus.

METHODS: The two-round Delphi method was adopted, with an iterative process consisting of two rounds of email questionnaires. Potential panelists were recruited via e-mail from all over the world based on their expertise on dermoscopy of non-neoplastic dermatoses in skin of color.

RESULTS: Twenty-two panelists took part in the validation process. All of the five originally proposed parameters and subitems reached agreement during the first round, aside from "follicular red dots." Additionally, during round 1, five new subitems were proposed (perifollicular scales distribution, follicular openings obliteration, broken hairs, eccrine pigmentation, and eccrine ostia obliteration), along with the possibility to change the denomination of parameter 3 (from "follicular findings" to "follicular/eccrine findings") and split it into two subparameters ("follicular findings" and "eccrine findings"). All such proposals reached agreement during the second round and therefore were included in the final list, for a total of 37 items.

CONCLUSIONS: Although nearly all the dermoscopic criteria originally proposed by the IDS are applicable even to darker phototypes, several additional variables need to be assessed.

R.S.Abdellatif, H., G. Zhang, D. Xie, JiupaiNia, and ChengshengNia, "Ionic Salt-Mediated Tuning of the Morphology and Band Structure of Graphitic Carbon Nitride for NO Removal under Visible Light", ACS Applied Nano Materials, vol. 4, issue 3, pp. 2828 - 2839, 2021.
Hassan, H. K., A. Galal, N. F. Atta, and T. Jacob, "Iron-based perovskites-reduced graphene oxide as possible cathode materials for rechargeable iron-ion battery", Journal of Alloys and Compounds, vol. 870, pp. 159383, 2021.
Marmouzi, I., S. M. Ezzat, E. S. Mostafa, M. E. Jemli, R. A. Radwan, M. E. A. Faouzi, N. Tamsouri, and Mourad Kharbach, "Isolation of secondary metabolites from the mediterranean sponge species; Hemimycale columella and its biological properties", SN Applied Science, vol. 3, pp. 1-13, 2021.
S.Almuhayawi, M., A. H.A.Hassan, S. K. A. Jaouni, S. Selim, M. Abdel-Mawgoud, G. Khamis, and H. AbdElgawad, "Laser light as a promising approach to improve the nutritional value, antioxidant capacity and anti-inflammatory activity of flavonoid-rich buckwheat sprouts", Food Chemistry, 2021.
Alshehri, A. A., A. M. Alshehri, A. A. Muthanna, A. U. Syed, A. R. Abdelrehim, A. M. Edrees, A. M. Dohain, A. F. Elmahrouk, A. A. Jamjoom, and O. O. Al‑Radi, "Long-term surgical outcomes after repair of multiple ventricular septal defects in pediatrics", The Cardiothoracic Surgeon, 2021. outcomes_after_repair_of_multiple_ventricular_septal_defects.pdf
Ishida, R., J. Cole, J. Lopez-Orozco, N. Fayad, A. Felix-Lopez, M. Elaish, S. Y. Luo, O. Julien, A. Kumar, and T. C. Hobman, "Mayaro Virus Non-Structural Protein 2 Circumvents the Induction of Interferon in Part by Depleting Host Transcription Initiation Factor IIE Subunit 2", Cells, vol. 10, no. 12, 2021. AbstractWebsite

Mayaro virus (MAYV) is an emerging mosquito-transmitted virus that belongs to the genus

Jaleel, G. A. A., S. S. Azab, W. M. El-Bakly, and A. Hassan, "Methyl palmitate attenuates adjuvant induced arthritis in rats by decrease of CD68 synovial macrophages", Biomedicine & Pharmacotherapy, vol. 137, pp. 1-9, 2021. 1-s2.0-s0753332221001323-main.pdf
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