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Chatrchyan, S., V. Khachatryan, A. M. Sirunyan, A. Tumasyan, W. Adam, E. Aguilo, T. Bergauer, M. Dragicevic, J. Erö, C. Fabjan, et al., "Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs", Physical Review Letters, vol. 110, no. 8, 2013. AbstractWebsite
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Chatrchyan, S., V. Khachatryan, A. M. Sirunyan, A. Tumasyan, W. Adam, E. Aguilo, T. Bergauer, M. Dragicevic, J. Erö, C. Fabjan, et al., "Study of the inclusive production of charged pions, kaons, and protons in pp collisions at √s = 0.9,2.76 and 7 TeV", European Physical Journal C, vol. 72, no. 10, pp. 1-37, 2012. AbstractWebsite
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Chatrchyan, S., V. Khachatryan, A. M. Sirunyan, A. Tumasyan, W. Adam, E. Aguilo, T. Bergauer, M. Dragicevic, J. Erö, C. Fabjan, et al., "Study of the dijet mass spectrum in pp→W+jets events at √s=7 TeV", Physical Review Letters, vol. 109, no. 25, 2012. AbstractWebsite
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Chatrchyan, S., V. Khachatryan, A. M. Sirunyan, A. Tumasyan, W. Adam, T. Bergauer, M. Dragicevic, J. Erö, C. Fabjan, M. Friedl, et al., "Study of high-p T charged particle suppression in PbPb compared to pp collisions at √S NN=2.76 TeV", European Physical Journal C, vol. 72, no. 3, pp. 1-22, 2012. AbstractWebsite
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Chatrchyan, S., R. Erbacher, C. A. Carrillo Montoya, C. - S. Moon, W. Carvalho, M. Górski, D. Kotlinski, J. Anderson, P. Jez, B. Ujvari, et al., Study of double parton scattering using W+ 2-jet events in proton-proton collisions at sqrt (s)= 7 TeV, , 2013. Abstract
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Abdelrazek, F. M., N. H. Metwally, N. A. Kassab, M. T. Jaafer, P. Metz, and A. Jaeger, "Studies on the reaction of cycloalkanones with malonodinitrile.", J. Heterocyclic Chem., vol. 51, issue 5, pp. 1785-1780, 2014.
Chatrchyan, S., V. Khachatryan, A. M. Sirunyan, A. Tumasyan, W. Adam, T. Bergauer, M. Dragicevic, J. Erö, C. Fabjan, M. Friedl, et al., "Studies of jet quenching using isolated-photon+jet correlations in PbPb and pp collisions at sNN=2.76TeV", Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics, vol. 718, no. 3, pp. 773-794, 2013. AbstractWebsite
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Chatrchyan, S., R. Erbacher, C. A. Carrillo Montoya, C. - S. Moon, W. Carvalho, M. Górski, D. Kotlinski, J. Anderson, P. Jez, B. Ujvari, et al., Studies of dijet pseudorapidity distributions and transverse momentum balance in pPb collisions at sqrt (s [NN])= 5.02 TeV, , 2014. Abstract
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Hegazi, N. A., and V. Jensen, "Studies of Azotobacter bacteriophages in Egyptian soils.", Soil Biol. Biochem., vol. 5, pp. 231-243 , 1972.
Ismail, M. E. H., S. J. Johnston, and Z. S. Mansour, "Structure relations for q-polynomials and some applications", Applicable Analysis, vol. 90, issue 3-4: Taylor & Francis, pp. 747-767, 2011. Abstract
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MANSOUR, M. S., A. M. Elbaz, W. L. Roberts, M. F. Zayed, M. Juddoo, B. M. Akoush, A. M. Khedr, H. M. Al-Bulqini, and A. R. Masri, "Structure and stability characteristics of turbulent planar flames with inhomogeneous jet in a concentric flow slot burner", Proceedings of the Combustion Institute: Elsevier, 2020. Abstract
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MANSOUR, M. S., A. M. Elbaz, W. L. Roberts, M. F. Zayed, M. Juddoo, B. M. Akoush, A. M. Khedr, H. M. Al-Bulqini, and A. R. Masri, "Structure and stability characteristics of turbulent planar flames with inhomogeneous jet in a concentric flow slot burner", Proceedings of the Combustion Institute, vol. 38, no. 2, pp. 2597-2606, 2021. AbstractWebsite

Turbulent flames with compositionally inhomogeneous mixtures are common in many combustion systems. Turbulent jet flames with a circular nozzle burner were used earlier to study the impact of inhomogeneous mixtures, and these studies showed that the nozzle radius affects the flame stability. Accordingly, planar turbulent flames with inhomogeneous turbulent jet are created in a concentric flow slot burner (CFSB) to avoid this effect in the present study. The stability characteristics, the mixing field structure, and the flame front structure were measured, and the correlations between stability and the mixing field structure were investigated. The mixture fraction field was measured in non-reacting jets at the nozzle exit using highly resolved Rayleigh scattering technique, and the flame front was measured in some selected turbulent flames using high-speed Planar Laser-Induced Fluorescence (PLIF) of OH technique. The data show strong correlations between flame stability and the range of mixture fraction fluctuations. The flames are highly stabilized within a mixing field environment with the range of fluctuation in mixture fraction close to the range of the flammability limits. The mixing field structure is also illustrated and discussed using a mixing regime diagram and showed that the scatter of the data of the different cases is consistent with the classified mixing regimes. Lean flames are stabilized in the current slot burner. The flame front structure topology varies consistently from thin, small curvature at the low level of turbulence and higher equivalence ratio to more wrinkled, larger curvature, but a thicker structure at a higher level of turbulence and lower equivalence ratio.

Kim, J. M., S. Kim, S. W. Hwang, C. O. Kim, D. H. Shin, J. H. Kim, C. W. Jang, S. S. Kang, E. Hwang, S. - H. Choi, et al., "Strong enhancement of emission efficiency in GaN light-emitting diodes by plasmon-coupled light amplification of graphene", Nanotechnology, vol. 29, no. 5: IOP Publishing, pp. 055201, 2018. Abstract
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Kim, J. M., S. Kim, S. W. Hwang, C. O. Kim, D. H. Shin, J. H. Kim, C. W. Jang, S. S. Kang, E. Hwang, S. - H. Choi, et al., "Strong enhancement of emission efficiency in GaN light-emitting diodes by plasmon-coupled light amplification of graphene", Nanotechnology, vol. 29, no. 5: IOP Publishing, pp. 055201, 2018. Abstract
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Kim, J. M., S. Kim, S. W. Hwang, C. O. Kim, D. H. Shin, J. H. Kim, C. W. Jang, S. S. Kang, E. Hwang, S. - H. Choi, et al., "Strong enhancement of emission efficiency in GaN light-emitting diodes by plasmon-coupled light amplification of graphene", Nanotechnology, vol. 29, no. 5: IOP Publishing, pp. 055201, 2018. Abstract
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Krishnamurthi, R. V., G. deVeber, V. L. Feigin, S. Barker-Collo, H. Fullerton, M. T. Mackay, F. O'Callahan, P. M. Lindsay, A. Kolk, W. Lo, et al., "Stroke Prevalence, Mortality and Disability-Adjusted Life Years in Children and Youth Aged 0-19 Years: Data from the Global and Regional Burden of Stroke 2013.", Neuroepidemiology, vol. 45, issue 3, pp. 177-89, 2015. Abstract

BACKGROUND: There is increasing recognition of stroke as an important contributor to childhood morbidity and mortality. Current estimates of global childhood stroke burden and its temporal trends are sparse. Accurate and up-to-date estimates of childhood stroke burden are important for planning research and the resulting evidence-based strategies for stroke prevention and management.

OBJECTIVES: To estimate the prevalence, mortality and disability-adjusted life years (DALYs) for ischemic stroke (IS), hemorrhagic stroke (HS) and all stroke types combined globally from 1990 to 2013.

METHODOLOGY: Stroke prevalence, mortality and DALYs were estimated using the Global Burden of Disease 2013 methods. All available data on stroke-related incidence, prevalence, excess mortality and deaths were collected. Statistical models and country-level covariates were employed to produce comprehensive and consistent estimates of prevalence and mortality. Stroke-specific disability weights were used to estimate years lived with disability and DALYs. Means and 95% uncertainty intervals (UIs) were calculated for prevalence, mortality and DALYs. The median of the percent change and 95% UI were determined for the period from 1990 to 2013.

RESULTS: In 2013, there were 97,792 (95% UI 90,564-106,016) prevalent cases of childhood IS and 67,621 (95% UI 62,899-72,214) prevalent cases of childhood HS, reflecting an increase of approximately 35% in the absolute numbers of prevalent childhood strokes since 1990. There were 33,069 (95% UI 28,627-38,998) deaths and 2,615,118 (95% UI 2,265,801-3,090,822) DALYs due to childhood stroke in 2013 globally, reflecting an approximately 200% decrease in the absolute numbers of death and DALYs in childhood stroke since 1990. Between 1990 and 2013, there were significant increases in the global prevalence rates of childhood IS, as well as significant decreases in the global death rate and DALYs rate of all strokes in those of age 0-19 years. While prevalence rates for childhood IS and HS decreased significantly in developed countries, a decline was seen only in HS, with no change in prevalence rates of IS, in developing countries. The childhood stroke DALY rates in 2013 were 13.3 (95% UI 10.6-17.1) for IS and 92.7 (95% UI 80.5-109.7) for HS per 100,000. While the prevalence of childhood IS compared to childhood HS was similar globally, the death rate and DALY rate of HS was 6- to 7-fold higher than that of IS. In 2013, the prevalence rate of both childhood IS and HS was significantly higher in developed countries than in developing countries. Conversely, both death and DALY rates for all stroke types were significantly lower in developed countries than in developing countries in 2013. Men showed a trend toward higher childhood stroke death rates (1.5 (1.3-1.8) per 100,000) than women (1.1 (0.9-1.5) per 100,000) and higher childhood stroke DALY rates (120.1 (100.8-143.4) per 100,000) than women (90.9 (74.6-122.4) per 100,000) globally in 2013.

CONCLUSIONS: Globally, between 1990 and 2013, there was a significant increase in the absolute number of prevalent childhood strokes, while absolute numbers and rates of both deaths and DALYs declined significantly. The gap in childhood stroke burden between developed and developing countries is closing; however, in 2013, childhood stroke burden in terms of absolute numbers of prevalent strokes, deaths and DALYs remained much higher in developing countries. There is an urgent need to address these disparities with both global and country-level initiatives targeting prevention as well as improved access to acute and chronic stroke care.

Krishnamurthi, R. V., A. E. Moran, V. L. Feigin, S. Barker-Collo, B. Norrving, G. A. Mensah, S. Taylor, M. Naghavi, M. H. Forouzanfar, G. Nguyen, et al., "Stroke Prevalence, Mortality and Disability-Adjusted Life Years in Adults Aged 20-64 Years in 1990-2013: Data from the Global Burden of Disease 2013 Study.", Neuroepidemiology, vol. 45, issue 3, pp. 190-202, 2015. Abstract

BACKGROUND: Recent evidence suggests that stroke is increasing as a cause of morbidity and mortality in younger adults, where it carries particular significance for working individuals. Accurate and up-to-date estimates of stroke burden are important for planning stroke prevention and management in younger adults.

OBJECTIVES: This study aims to estimate prevalence, mortality and disability-adjusted life years (DALYs) and their trends for total, ischemic stroke (IS) and hemorrhagic stroke (HS) in the world for 1990-2013 in adults aged 20-64 years.

METHODOLOGY: Stroke prevalence, mortality and DALYs were estimated using the Global Burden of Disease (GBD) 2013 methods. All available data on rates of stroke incidence, excess mortality, prevalence and death were collected. Statistical models were used along with country-level covariates to estimate country-specific stroke burden. Stroke-specific disability weights were used to compute years lived with disability and DALYs. Means and 95% uncertainty intervals (UIs) were calculated for prevalence, mortality and DALYs. The median of the percent change and 95% UI were determined for the period from 1990 to 2013.

RESULTS: In 2013, in younger adults aged 20-64 years, the global prevalence of HS was 3,725,085 cases (95% UI 3,548,098-3,871,018) and IS was 7,258,216 cases (95% UI 6,996,272-7,569,403). Globally, between 1990 and 2013, there were significant increases in absolute numbers and prevalence rates of both HS and IS for younger adults. There were 1,483,707 (95% UI 1,340,579-1,658,929) stroke deaths globally among younger adults but the number of deaths from HS (1,047,735 (95% UI 945,087-1,184,192)) was significantly higher than the number of deaths from IS (435,972 (95% UI 354,018-504,656)). There was a 20.1% (95% UI -23.6 to -10.3) decline in the number of total stroke deaths among younger adults in developed countries but a 36.7% (95% UI 26.3-48.5) increase in developing countries. Death rates for all strokes among younger adults declined significantly in developing countries from 47 (95% UI 42.6-51.7) in 1990 to 39 (95% UI 35.0-43.8) in 2013. Death rates for all strokes among younger adults also declined significantly in developed countries from 33.3 (95% UI 29.8-37.0) in 1990 to 23.5 (95% UI 21.1-26.9) in 2013. A significant decrease in HS death rates for younger adults was seen only in developed countries between 1990 and 2013 (19.8 (95% UI 16.9-22.6) and 13.7 (95% UI 12.1-15.9)) per 100,000). No significant change was detected in IS death rates among younger adults. The total DALYs from all strokes in those aged 20-64 years was 51,429,440 (95% UI 46,561,382-57,320,085). Globally, there was a 24.4% (95% UI 16.6-33.8) increase in total DALY numbers for this age group, with a 20% (95% UI 11.7-31.1) and 37.3% (95% UI 23.4-52.2) increase in HS and IS numbers, respectively.

CONCLUSIONS: Between 1990 and 2013, there were significant increases in prevalent cases, total deaths and DALYs due to HS and IS in younger adults aged 20-64 years. Death and DALY rates declined in both developed and developing countries but a significant increase in absolute numbers of stroke deaths among younger adults was detected in developing countries. Most of the burden of stroke was in developing countries. In 2013, the greatest burden of stroke among younger adults was due to HS. While the trends in declining death and DALY rates in developing countries are encouraging, these regions still fall far behind those of developed regions of the world. A more aggressive approach toward primary prevention and increased access to adequate healthcare services for stroke is required to substantially narrow these disparities.

Jawad, S. F., F. M. A. Altalbawy, R. M. Hussein, A. A. Fadhil, M. A. Jawad, R. S. Zabibah, T. Y. Taraki, C. D. Mohan, and K. S. Rangappa, "The strict regulation of HIF‑1α by non‑coding RNAs: new insight towards proliferation, metastasis, and therapeutic resistance strategies", Cancer and Metastasis Reviews, 2023.
Lee, C., M. Mannaa, N. Kim, J. Kim, Y. Choi, S. H. Kim, B. Jung, H. - H. Lee, J. Lee, and Y. - S. Seo, "Stress tolerance and virulence-related roles of lipopolysaccharide in Burkholderia glumae", The plant pathology journal, vol. 35, issue 5: The Korean Society of Plant Pathology, pp. 445, 2019. Abstract
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Lee, C., M. Mannaa, N. Kim, J. Kim, Y. Choi, S. H. Kim, B. Jung, H. - H. Lee, J. Lee, and Y. - S. Seo, "Stress tolerance and virulence-related roles of lipopolysaccharide in Burkholderia glumae", The plant pathology journal, vol. 35, issue 5: The Korean Society of Plant Pathology, pp. 445, 2019. Abstract
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El-lethey, H., V. Aerni, T. W. Jungi, and B. Wechsler, "Stress and feather pecking in laying hens (Gallus gallus domesticus) in relation to housing conditions", Br. Poult. Sci., vol. 41, pp. 22-28, 2000.
Gao, Y., D. - C. Huang, C. Liu, Z. - L. Song, J. - R. Liu, S. - K. Guo, J. - Y. Tan, R. - L. Qiu, B. Jin, H. Zhang, et al., "Streptochlorin analogues as potential antifungal agents: Design, synthesis, antifungal activity and molecular docking study", Bioorganic & Medicinal Chemistry, vol. 35, pp. 116073, 2021. AbstractWebsite

Streptochlorin is a small molecule of indole alkaloid isolated from marine Streptomyces sp., it is a promising lead compound due to its potent bioactivity in preventing many phytopathogens in our previous study, but further structural modifications are required to improve its antifungal activity. Our work in this paper focused on the replacement of oxazole ring in streptochlorin with the imidazole ring, to discover novel analogues. Based on this design strategy, three series of streptochlorin analogues were efficiently synthesized through sequential Vilsmeier-Haack reaction, Van Leusen imidazole synthesis and halogenation reaction. Some of the analogues displayed excellent activity in the primary assays, and this is highlighted by compounds 4g and 4i, the growth inhibition against Alternaria Leaf Spot and Rhizoctorzia solani under 50 μg/mL are 97.5% and 90.3%, respectively, even more active than those of streptochlorin, pimprinine and Osthole. Molecular docking models indicated that streptochlorin binds with Thermus thermophiles Leucyl-tRNA Synthetase in a similar mode to AN2690, offering a perspective on the mode of action study for antifungal activities of streptochlorin derivatives. Further study is still ongoing with the aim of discovering synthetic analogues, with improved antifungal activity and clear mode of action.