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HUSSEIN, M. O. H. A. M. E. D. F. A. T. H. I., M. O. H. A. M. E. D. W. A. F. A. A. ZAKARIA, A. Soliman, and I. M. A. N. I. B. R. A. H. I. M. KAMAL, "STUDY OF GASTRO-ESOPHAGEAL REFLUX IN ASTHMATIC PATOENTS WOTHOUT REFLUX SYMPTOMS", THE EGYPTIAN JOURNAL OF CHEST DISEASES & TUBERCULOSIS , vol. 61-2, issue APRIL , 2012.
hussein, S. A., K. MahmoudKamel, S. Z. Kaddah, E. E. A. Elhamid, and M. M. Shaban, "Role of ultrasonography in assessment of anatomic upper airway changes in patients with obstructive sleep apnea", Advances in respiratory medicine, vol. 88, issue 6, pp. 548-557, 2020.
Hussein, M. A., M. I. Ellawindi, and G. Ragab, "Performance of classification criteria for Behcet's disease in an Egyptian cohort", Indian Journal of Rheumatology, vol. 12, issue 3: Medknow Publications, pp. 152, 2017. Abstract
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Hussein, Z. M., T. A. El-Tayeb, F. El-Keraby, and M. A. Harith, "The effect of diode laser and light emitting diode on the bacterial contamination of semen medium for artificial insemination", Biologicals, vol. 36, issue 5: Academic Press, pp. 303-307, 2008. Abstract
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Hussein, G. M., G. A. Abu El-Heba, S. M. Abdou, and N. A. Abdallah, "Optimization of transient gene expression system in Gerbera jemosonii petals", GM crops & food, vol. 4, issue 1: Taylor & Francis, pp. 50-57, 2013. Abstract
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Hussein, H. A. S., M. M. F. Abdalla, L. Hindi, A. F. Ibrahim, and A. N. Sharaan, "Biometrical analysis of radiation-induced early flowering barley mutants and associated characters", Egyptian journal of genetics and cytology, 1980. Abstract
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Hussein, H. T., H. A. Hassan, H. H. R. Madkor, A. A. Abdel-Ghany, and K. A. Ahmed, "THE ROLE OF VISFATIN AND CYTOGLOBIN IN OBESE DIABETIC RATS: THE MODULATORY EFFECTS OF RASPBERRY KETONE", Bulletin of Pharmaceutical Sciences Assiut University, vol. 43, issue 1, pp. 53-72, 2020.
Hussein, H., C. Suarez, M. ueti, G. Scoles, D. Schneider, and wendell Johnson, "Babesia bovis sexual stages induced in in vitro culture", Washington state show case, Pullman, WA, USA, 27 March 2017. hussein-hala-poster.pdf
Hussein, H. E., G. A. R. Bohaliga, W. C. Johnson, and R. O’Connor, "Identification of a putative methyltransferase gene of Babesia bigemina as a novel molecular biomarker uniquely expressed in parasite tick stages", Parasites & Vectors , vol. 11, pp. 480-493, 2018. identification.pdf
Hussein, A. A., S. Dibaj, N. Hinata, E. Field, K. O'leary, B. Kuvshinoff, J. L. Mohler, G. Wilding, and K. A. Guru, "Development and Validation of a Quality Assurance Score for Robot-Assisted Radical Cystectomy: a 10-Year Analysis.", Urology, 2016 Aug 1. Abstract

OBJECTIVE: To develop quality assessment tool to evaluate surgical performance for robot-assisted radical cystectomy (RARC) program.

METHODS: A prospectively maintained quality assurance database of 425 consecutive RARCs performed by a single surgeon between 2005 and 2015 was retrospectively reviewed. Potentially modifiable factors, related to the management and perioperative care of patients were used to evaluate patient care. Criteria included: Preoperative (administration of neoadjuvant chemotherapy); Operative (operative time <6.5 hours and estimated blood loss <500cc); Pathologic (negative soft tissue surgical margins and lymph node yield ≥20); and Postoperative (no high grade complications, readmission or non-cancer related mortality within 30 d).The Quality Cystectomy Score (QCS) was developed (1 star: achieving ≤2 criteria or mortality within 30 d; 2 stars: 3 or 4 criteria met; and 3 stars: 5 or 6 criteria met; 4 stars: 7 or all criteria met). Univariate and multivariate Cox proportional hazard regression models were fitted to test for the association between QCS and survival outcomes.

RESULTS: Most patients (85%) achieved at least 3 stars, and more patients achieved 4 stars with time. High QCS was associated with better recurrence free (RFS), cancer specific (CSS) and overall survival (OS) (p-values <0.05). None of the patients with 1-star were alive at 1 yr. Patients with 4 stars achieved the best survival rates (RFS 62%, CSS 70% and OS 53% at 5 yrs) (log rank p<0.0001).

CONCLUSION: Continuous assessment for quality improvement facilitated implementation and maintenance of robot-assisted program for bladder cancer.

Hussein, H. A., B. M. Ahmed, S. M. Aly, A. H. El-deeb, A. A. El-Sanousi, M. A. Rohaim, A. A. Arafa, and M. R. Gadalla, "Protective efficacy of a prime-boost protocol using H5-DNA plasmid as prime and inactivated H5N2 vaccine as the booster against the Egyptian avian influenza challenge virus.", Acta virologica, vol. 60, no. 3, pp. 307–315, 2016. Abstract
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Hussein, M. A., I. M. Eissa, and A. A. Dahab, "Vision-Threatening Behcet’s Disease: Severity of Ocular Involvement Predictors", ophthalmology, vol. https://doi.org/10.1155/2018/9518065, 2018. Vision-Threatening Behcet’s Disease: Severity of Ocular Involvement Predictors.pdf
Hussein, A. A., C. J. Welty, N. Ameli, J. E. Cowan, M. Leapman, S. P. Porten, K. Shinohara, and P. R. Carroll, "Untreated Gleason Grade Progression on Serial Biopsies during Prostate Cancer Active Surveillance: Clinical Course and Pathological Outcomes.", The Journal of urology, vol. 194, issue 1, pp. 85-90, 2015 Jul. Abstract

PURPOSE: We describe the outcomes of patients with low risk localized prostate cancer who were upgraded on a surveillance biopsy while on active surveillance and evaluated whether delayed treatment was associated with adverse outcome.

MATERIALS AND METHODS: We included men in the study with lower risk disease managed initially with active surveillance and upgraded to Gleason score 3+4 or greater. Patient demographics and disease characteristics were compared. Kaplan-Meier curve was used to estimate the treatment-free probability stratified by initial upgrade (3+4 vs 4+3 or greater), Cox regression analysis was used to examine factors associated with treatment and multivariate logistic regression analysis was used to evaluate the factors associated with adverse outcome at surgery.

RESULTS: The final cohort comprised 219 men, with 150 (68%) upgraded to 3+4 and 69 (32%) to 4+3 or greater. Median time to upgrade was 23 months (IQR 11-49). A total of 163 men (74%) sought treatment, the majority (69%) with radical prostatectomy. The treatment-free survival rate at 5 years was 22% for 3+4 and 10% for 4+3 or greater upgrade. Upgrade to 4+3 or greater, higher prostate specific antigen density at diagnosis and shorter time to initial upgrade were associated with treatment. At surgical pathology 34% of cancers were downgraded while 6% were upgraded. Cancer volume at initial upgrade was associated with adverse pathological outcome at surgery (OR 3.33, 95% CI 1.19-9.29, p=0.02).

CONCLUSIONS: After Gleason score upgrade most patients elected treatment with radical prostatectomy. Among men who deferred definitive intervention, few experienced additional upgrading. At radical prostatectomy only 6% of cases were upgraded further and only tumor volume at initial upgrade was significantly associated with adverse pathological outcome.

Hussein, A. A., and J. F. Smith, "Oncofertility: Current practice and vision for the future", Urology Times, 2014. Website
Hussein, M. M., In vitro propagation of three species of Aglaonema plants, : جمعية كلية الزراعة العربية-جامعة عين شمس-القاهرة, 2013. Abstract
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Hussein, H. E., G. A. Scoles, M. W. Ueti, F. K. Adham, C. E. Suarez, F. D. Guerrero, and R. G. Bastos, "Targeted silencing of the Aquaporin 2 gene of Rhipicephalus (Boophilus) microplus reduces tick fitness", Parasites & vectors, vol. 8, issue 1756-3305, pp. 618-630, 2015. aquaporin2_full_text.pdf
Hussein, G. M., S. S. Muhammad, N. A. Gomaa, M. R. Shehata, and W. M. Hosny, "Potentiality of methyltrioctylammonium chloride ligand for selective extraction of the Uranium (VI) metal ions from selective carbonate leach liquor", Journal of Dispersion Science and Technology, vol. 38, issue 8: Taylor & Francis, pp. 1204-1210, 2017. Abstract
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Hussein, M. A., H. Hassan, and M. Nassef, "Automated language essay scoring systems: A literature review", PeerJ Computer Science, vol. 5: PeerJ Inc., pp. e208, 2019. Abstract
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Hussein, M. M. M., and A. A. Haggag, "EFFECT OF IRRIGATION INTERVALS AND SALT CONCENTRATIONS ON THE GROWTH AND CHEMICAL COMPOSITION OF ASCLEPIAS CURASSAVICA L", ANNALS OF AGRICULTURAL SCIENCE-CAIRO-, vol. 48, issue 1: AIN SHAMS UNIVERSITY, pp. 307-328, 2003. Abstract
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Hussein, A. A., Y. E. Ahmed, J. D. Kozlowski, P. May, J. Nyquist, S. Sexton, L. Curtin, J. O. Peabody, H. Abol-Enein, and K. A. Guru, "Robot-Assisted Approach to W Configuration Urinary Diversion:A Step-by-Step Technique.", BJU international, 2017 Feb 20. Abstract

INTRODUCTION: To describe a detailed step-by-step approach of our technique to robot-assisted intracorporeal "W" orthotopic ileal neobladder (ICNB).

METHODS: Five patients underwent robot-assisted radical cystectomy (RARC), extended pelvic lymph node dissection (ePLND) and ICNB. ICNB was divided into 6 key steps to facilitate and enable a detailed analysis and auditing of the technique. No conversion to open surgery was required. Timing for each step was noted. All patients had at least 3 months of follow up.

RESULTS: Mean age was 57 years. Mean overall console and diversion times were 357 and 193 minutes, respectively. None of the patients had any evidence of residual disease following RARC. Four of five patients experienced complications; 3 developed fevers due to urinary tract infection (one required readmission), and 1 patient developed myocardial infarction and required coronary angiography and stenting. Looking at the timing for the individual steps, bowel detubularization and construction of posterior plate were consistently the longest among the key steps (average 46 minutes, 13% of the overall operative time), followed by uretero-ileal anastomosis (37 minutes, 10%), neobladder-urethral anastomosis (23 minutes, 6%) and identification and fixation of the bowel (26 minutes, 7%).

CONCLUSION: We described our step-by-step technique and initial perioperative outcomes of our first five intracorporeal neobladders with "W" configuration This article is protected by copyright. All rights reserved.

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