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Huthinson, B. G., and I. A. EI-Khodary, "Spatial Dynamics of the Greater Toronto Area and the Impact on Commuting Demands", 71st Transportation Research Board Annual Meeting, Washington DC, USA, January, 1992.
Hutchinson, P., E. E. Khalil, J. H. Whitelaw, and G. Wigley, "The Calculation of Furnace Flow Properties and Their Experimental Verification", ASME J. Heat Transfer, vol. 98, issue 1, pp. 276-283, 1975.
Hutchinson, P. J., A. G. Kolias, T. Tajsic, A. Adeleye, A. T. Aklilu, T. Apriawan, A. H. Bajamal, E. J. Barthélemy, I. B. Devi, D. Bhat, et al., "Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury : Consensus statement.", Acta neurochirurgica, vol. 161, issue 7, pp. 1261-1274, 2019. Abstract

BACKGROUND: Two randomised trials assessing the effectiveness of decompressive craniectomy (DC) following traumatic brain injury (TBI) were published in recent years: DECRA in 2011 and RESCUEicp in 2016. As the results have generated debate amongst clinicians and researchers working in the field of TBI worldwide, it was felt necessary to provide general guidance on the use of DC following TBI and identify areas of ongoing uncertainty via a consensus-based approach.

METHODS: The International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury took place in Cambridge, UK, on the 28th and 29th September 2017. The meeting was jointly organised by the World Federation of Neurosurgical Societies (WFNS), AO/Global Neuro and the NIHR Global Health Research Group on Neurotrauma. Discussions and voting were organised around six pre-specified themes: (1) primary DC for mass lesions, (2) secondary DC for intracranial hypertension, (3) peri-operative care, (4) surgical technique, (5) cranial reconstruction and (6) DC in low- and middle-income countries.

RESULTS: The invited participants discussed existing published evidence and proposed consensus statements. Statements required an agreement threshold of more than 70% by blinded voting for approval.

CONCLUSIONS: In this manuscript, we present the final consensus-based recommendations. We have also identified areas of uncertainty, where further research is required, including the role of primary DC, the role of hinge craniotomy and the optimal timing and material for skull reconstruction.

Hutchinson, P. J., A. G. Kolias, T. Tajsic, and N. M. F. El-Ghandour, "Consensus Statement from International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury", Acta Neurochirurgica, vol. 161, pp. 1261-1274, 2019.
Hussseinm, M. H., and R. A. A. Younis, "Molecular identification of some alfalfa (Medicago sativa L.) cultivars grown in Egypt and Saudi Arabia using RAPD and ISSR.", Arab J. Biotech., vol. 9, issue 2, pp. 297-312, 2006. Abstract
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Hussine, A. A., M. Darhos, M. S. Eldin, and L. M. Fathi, THE EFFECT OF CALCIUM AND VITAMIN K WITH OR WITHOUT LOW INTENSITY LASER IRRADIATION ON INDUCED OSTEOPOROSIS IN EXPERIMENTAL RATS, , Giza, Egyptian Detail Journal, 2011. Abstract

This study was conducted on sixty adult albino rats in attempt to evaluate the effect of calcium, vitamink, low intensity laser therapy and their combination on the histopathlogical bony changes in induced osteoporosis. Ten rats were maintained on normal diet, the remaining fifty rats were divided into three groups. Group A was received no drug. Group B was received calcium and subjected to laser on right side. Group C was received calcium and vitamin K and subjected to laser on the right side

Hussin M. Abdel Moneim, L. Z. Ismail, G. A. Fattah, and Z. A. Zohdy, "Radiative Fluorescence Life Time of Rodamin-6G Doped PVC", Polymer Testing, vol. 20, issue 2, pp. 135-139, 2001.
Hussin M. Abdel Moneim, Lotfy Z. Ismail, G. A. F., and Z. A. Zohdy, "Radiative Fluorescence Life Time of Rodamin-6G Doped PVC", Polymer Testing, vol. 20, no. 2, pp. pp135–139, 2001. Abstract
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Hussieny, O. A. A. - A., M. A. El-Beltagy, and S. El-Tantawy, " [PDF] from researchgate.net Forecasting of renewable energy using ANN, GPANN and ANFIS (A comparative study and performance analysis)", 2020 2nd Novel Intelligent and Leading Emerging Sciences Conference (NILES): IEEE, pp. 54-59, 2020.
Hussieny, A. A. A., Y. M. K. Akl, R. I. Elkorashy, A. I. Mostafa, D. H. Attia, M. Faheem, and F. E. - Z. Ahmed, "Functional evaluation of patients with progressive systemic sclerosis-associated diffuse parenchymal lung disease", The Egyptian Journal of Chest Diseases and Tuberculosis, vol. 68, pp. 44–49, 2019.
Hussieny, O. A. A. - A., M. A. El-Beltagy, and S. El-Tantawy, "Forecasting of renewable energy using ANN, GPANN and ANFIS (A comparative study and performance analysis)", 2020 2nd Novel Intelligent and Leading Emerging Sciences Conference (NILES), pp. 54-59, 2020. Abstract
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Hussiena, E. M., M. M. Ibrahima, Y. M. Issab, F. M. Abdel-Gawada, and S. Barakata, "Application of TLC- Densitometry, First Derivative and Ratio Derivative Spectrophotometry for the Determination of Eprosartan Mesylate and Hydrochlorothiazide in Pharmaceutical Preparations", International Journal of Drug Development and Research, 2011. Abstract

Three sensitive and accurate methods are described for the direct determination of eprosartan mesylate (EPM) and hydrochlorothiazide (HCT) in bulk powder and combined dosage form without prior separation. The first method is a first derivative spectrophotometry (1D) using a zerocrossing technique of measurement at 240.7 nm for EPM and at 233.4 nm for HCT. The second method is the first derivative of ratio spectrophotometry (1DD) where the amplitudes were measured at 237.0 nm for EPM and at 277.0 nm for HCT. The third method is based on TLCseparation of the two drugs followed by densitometric measurements of their spots at 290 and 270

Hussiena, E. M., F. M. Abdel-Gawad, and Y. M. Issa, "Ion-selective electrodes for determination of fluoxetine in capsules and inbiological fluids", Biochemical Engineering Journal, 2011.
Hussien Rizk, C. -author.1999, Essential Cardiology, , 1999.
Hussien Rizk, C. -author, Essentials of electrocardiography, , 2004.
Hussien Helal, M., S. Mahmoud Mansour, H. A. E. Ahmed, A. F. A. Ghany, O. F. Kamel, and N. G. E. Kholy, "The role of contrast-enhanced spectral mammography in the evaluation of the postoperative breast cancer", Clinical Radiology , vol. 74, issue 10, pp. 771-781, 2019. post_operative_and_cesm.pdf
Hussien Helal, M., S. Mahmoud Mansour, L. A. Salaleldin, B. M. Alkalaawy, D. S. Salem, and N. M. Mokhtar, "The impact of contrast-enhanced spectral mammogram (CESM) and three-dimensional breast ultrasound (3DUS) on the characterization of the disease extend in cancer patients.", The British journal of radiology, vol. 91, issue 1087, pp. 20170977, 2018 Jul. Abstract

OBJECTIVE: The main importance of imaging breast cancer is to guide conservative surgeries. In this study, we evaluated the role of contrast-enhanced spectral mammogram (CESM) in correlation with three-dimensional (3D) breast ultrasound in characterizing the extension of the intramammary cancer in view of the: (i) the size of the main tumor, (ii) the multiplicity of the breast cancer, and (iii) the peri-tumoral stromal involvement (i.e. free or intraductal extension of the cancer).

METHODS: The study is a prospective analysis that included 300 breast masses proved to be malignant. The masses were evaluated for their size, multiplicity and surrounding stromal involvement. Contrast-based mammography performed with low (22-33 kVp) and high (44-49 kVp) energy exposures that were taken after i.v. injection of contrast agent and followed by bilateral 3D breast ultrasound. Operative data were the gold standard reference.

RESULTS: There was no significant difference between the sizes of the included cancers as measured by CESM and 3D ultrasound and that measured at the pathological analysis. CESM showed higher accuracy (32.7%, n = 98) than 3D ultrasound (24.7%, n = 74) in the size agreement within 5% range. CESM was the most accurate modality (94%, n = 282) in detecting tumor multiplicity, followed by traditional sonomammogram (88%, n = 264), then 3D breast ultrasound (84%, n = 252). Intraductal extension of the breast cancer was best evaluated by the 3D ultrasound with an accuracy value of 98% (n = 294) compared to only 60% (n = 180) by CESM.

CONCLUSION: CESM is a recommended investigation in breast cancer to increase the accuracy of size measurement and the detection of multiple tumors. The addition of 3D ultrasound can enhance the detection of intraductal extension. Advances in knowledge: Choice of conservative breast surgery vs mastectomy is still a debate. We used an advanced, contrast-based, application of the mammogram: CESM and a non-invasive 3D breast ultrasound in the assessment of the local extension of the breast cancer regarding size, perifocal stromal infiltration and multiplicity to guide the selection of proper management in proved cases of breast cancer.

Hussien Helal, M., ahmed morsy mostafa, S. Mansour, maissa kamel noaman, and manal mohamed refaat Beshir, "Loco-regional staging of cervical carcinoma: Is there a place for Multidetector CT?", Egyptian Journal of Radiology and Nuclear Medicine , vol. 48, pp. 307-311, 2017. loco-cervix.pdf
Hussien Helal, M., S. Mahmoud Mansour, L. A. S. E. Din, M. Zaglol, M. A. Haggag, and O. M. Nada, ""Staging of breast cancer and the advanced applications of digital mammogram: what the physician needs to know?"", The British journal of radiology · , vol. VOLUME 90, issue 1071, 2017. Website
Hussien Helal, M., S. Mahmoud Mansour, L. A. Salaleldin, B. M. Alkalaawy, D. S. Salem, and N. M. Mokhtar, "The impact of contrast-enhanced spectral mammogram (CESM) and three-dimensional breast ultrasound (3DUS) on the characterization of the disease extend in cancer patients", British Journal of Radiology , vol. 91, issue 1087, pp. 20170977, 2018.
Hussien Helal, M., S. Mansour, M. Zaglol, L. A. Salaeldin, O. M. Nada, and M. A. Haggag, "Staging of breast cancer and the advanced applications of digital mammogram: what the physician needs to know?", British Journal of Radiology, vol. 90, pp. 20160717., 2017.
Hussien Helal, M., S. Mahmoud Mansour, L. A. Salaleldin, B. M. Alkalaawy, D. S. Salem, and N. M. Mokhtar, "The impact of contrast-enhanced spectral mammogram (CESM) and three-dimensional breast ultrasound (3DUS) on the characterization of the disease extend in cancer patients", British Journal of Radiology, vol. 91, pp. 20170977, 2018. bjr.20170977_3d_us.pdf
Hussien, N. I., N. Ebrahim, O. M. Mohammed, and D. Sabry, "Combination of Obestatin and Bone Marrow Mesenchymal Stem Cells Prevents Aggravation of Endocrine Pancreatic Damage in Type II Diabetic Rats.", International journal of stem cells, vol. 10, issue 2, pp. 129-143, 2017 Nov 30. Abstractdiabetes_and_obostatin.pdf

One of the new promising therapies in treatment of diabetes mellitus is mesenchymal stem cells (MSCs) which have an interesting therapeutic potentiality based on their paracrine effect and transdifferentiation potentiality. Also obestatin improves the generation of functionalcells/islet-like cell clusters in vitro, suggesting implications for cell-based replacement therapy in diabetes. So the aim of this study was to evaluate the effect of combination of both MSCs and obestatin on an experimental model of type II diabetes mellitus (T2DM). Sixty male rats were divided into; group I (control group), group II (T2DM group) induced by administration of high fat diet (HFD) and injection of streptozotocin (STZ) in low dose, group III (T2DM treated with MSCs), group IV (T2DM treated with obestatin), group V (T2DM treated with MSCs and obestatin). Fasting blood glucose, C-peptide, insulin and lipid profile were measured. HOMA-IR and HOMA-were calculated. Pancreatic expression of insulin, glucagon like peptide -1 (GLP-1) and pancreatic duodenal homeobox 1 (Pdx1) mRNA levels were measured. In addition pancreatic histological changes, insulin and Bax were analyzed by immunohistochemical examination of islets of Langerhans. Diabetic rats showed significant increase in HOMA-IR, serum glucose and lipid profile levels with significant decrease in insulin, HOMA-, GLP-1 and Pdx1 levels. MSCs and obestatin caused significant improvement in all parameters with more significant improvement in combined therapy. The protective effects afforded by MSCs and obestatin may derive from improvement of the metabolic profile, antiapoptosis and by increase in pancreatic GLP-1and Pdx1 gene expression.

Hussien, Y. A., D. I. N. A. F. Mansour, S. A. Nada, S. S. Abd El-Rahman, R. M. Abdelsalam, A. S. Attia, and D. M. El-Tanbouly, "Linagliptin attenuates thioacetamide-induced hepatic encephalopathy in rats: Modulation of C/EBP-β and CX3CL1/Fractalkine, neuro-inflammation, oxidative stress and behavioral defects.", Life sciences, vol. 295, pp. 120378, 2022. Abstract

The degree of neuroinflammation is correlated mainly with cognitive and motor dysfunctions associated with hepatic encephalopathy (HE). The current study was conducted to explore the possible protective potential of the antidiabetic drug; linagliptin (LNG; 10 or 20 mg/kg) against HE induced by thioacetamide (TAA) in rats. Animals received two consecutive intraperitoneal injections of TAA (200 mg/kg) on alternate days. Neurobehavioral tests were performed 24 h after the last injection, and rats were sacrificed 24 h later (48 h). The higher LNG dose more effectively protected against TAA-induced changes. Administration of LNG for 15 days before TAA notably mitigated TAA-induced acute liver injury and HE, as verified by the marked improvement in motor coordination, locomotor activity, and cognition function. LNG maintained both brain and liver weight indices and retracted the hyperammonemia with a prominent suppression in liver transaminases. This was accompanied by an evident modulation of hepatic and hippocampal oxidative stress markers; GSH and MDA. LNG attenuated both liver and hippocampal pro-inflammatory cytokine; IL-1β while augmented the anti-inflammatory one; IL-10. It noticeably reduced hepatic and hippocampal COX-2 and TNF-α and maintained hepatic and brain architectures. It also induced a marked decrease in the inflammation-regulated transcription factor, C/EBP-β, with a profound increase in hippocampi's anti-inflammatory chemokine, CX3CL1/Fractalkine. LNG modulated TAA-induced disturbances in hippocampal amino acids; glutamate, and GABA with a significant increase in hippocampal BDNF. In conclusion, the regulatory effect of LNG on neuroinflammatory signaling underlines its neuroprotective effect against progressive encephalopathy accompanying acute liver injury.

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