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Galal, A., H. K. Hassan, and N. F. Atta, "Voltammetric Study of the Electrocatalytic Oxidation of Formaldehyde on Pt- Pd Co-catalyst Supported on Reduced Graphene Oxide", Electroanalysis, vol. 32, pp. 2733 – 2744, 2020.
Arafa, R. M., A. M. Mahmoud, B. M. Eltanany, and M. M. Galal, "Voltammetric determination of Oxybutynin Hydrochloride utilizing Pencil Graphite Electrode decorated with gold nanoparticles", Electroanalysis, vol. 35, issue 4, 2023.
Saad, A. S., A. M. Abou Al-Alamein, M. M. Galal, and H. E. Zaazaa, "Voltammetric determination of lidocaine and its toxic metabolite using C18 silica modified carbon paste electrode", Journal of the Electrochemical Society, vol. 166, issue 2, pp. B103-B109, 2019. Abstract

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Saad, A. S., A. A. M. Al-Alamein, M. M. Galal, and H. E. Zaazaa, "Voltammetric Determination of Lidocaine and Its Toxic Metabolite in Pharmaceutical Formulation and Milk Using Carbon Paste Electrode Modified with C18 Silica", Journal of the Electrochemical society, vol. 166, issue 2, pp. 103-109, 2019.
Saad, A. S., A. A. M. Al-Alamein, M. M. Galal, and H. E. Zaazaa, "Voltammetric Determination of Lidocaine and Its Toxic Metabolite in Pharmaceutical Formulation and Milk Using Carbon Paste Electrode Modified with C18 Silica", Journal of The Electrochemical Society, vol. 166(2), 2019.
Al-Alamein, A. A. M., A. S. Saad, M. M. Galal, and H. E. Zaazaa, "Voltammetric Determination of Lidocaine and Its Toxic Metabolite in Pharmaceutical Formulation and Milk Using Carbon Paste Electrode Modified with C18 Silica", Journal of The Electrochemical Society,, vol. 166 , issue 2, pp. B103-B109, 2019.
Atta, N. F., A. Galal, and R. A. Ahmed, "Voltammetric Behavior and Determination of Isoniazid Using PEDOT Electrode in Presence Of Surface Active Agents", Int. J. Electrochem. Sci. 6: 5097 - 5113 (2011) IF:2.808, vol. 6, pp. 5097-5113, 2011. AbstractCU-PDF.pdf

An electrochemical sensor was developed by using poly (3,4-ethylenedioxy thiophene) electrode in presence of different types of surfactants. Voltammetric behavior of isoniazid was studied at this electrode in the presence and absence of SDS and CTAB and interesting electrocatalytic effects were found. The presence of surfactant in the medium plays a key role in the electrostatic attraction and repulsion of isoniazid towards the polymeric surface in different pH values. The electrochemical behavior of isoniazid was investigated by cyclic voltammetry, linear sweep voltammetry (LSV), and electrochemical impedance spectroscopy (EIS). The linear response obtained for isoniazid was in the range of 0.1 to 8 ?mol L-1 and 10 to 100 ?mol L-1 with correlation coefficients of 0.999 and 0.998 and detection limits 32 nmol L-1 and 45 nmol L-1, respectively. The utility of this modified electrode was demonstrated for the determination of INH in human urine.

Ghobashy, R. H., M. M. Ismail Ali, and M. A. M. Hassan, "Voltage Regulation of PV System Connected to Grid Based on FOPID Controllers Using Evolutionary Computational Techniques", 2018 20th International Middle East Power Systems Conference, MEPCON 2018 - Proceedings, pp. 33-38, 2019. Abstract
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Hanafy, H. H., A. M. Gesraha, M. M. Abd-Elaziz, and A. F. Zobaa, "Voltage and Frequency Control of Self-Excited Short-Shunt Induction Generator", Journal of Engineering and Computer Sciences, Qassim University, vol. 1, issue 2, pp. 95-108, 2008.
Hafez, O., and H. Gindi, Voices of / from Africa, , Cairo, Cairo University Press, 2018.
El-Sayed, A., G. Ashour, M. Khalifa, and A. Gad, "Vitrification assessment of buffalo (Bubalus bubalis) oocytes: morphological and molecular aspects", Egyptian J. Anim. Prod, vol. 52, pp. 1-7, 2015. Abstract
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Abdelkawi, S. A., A. M. Abdel-Salam, D. F. Ghoniem, and S. K. Ghaly, "Vitreous Humor Rheology After Nd:YAG Laser Photo Disruption", Cell Biochem Biophys, pp. 267-274, 2014. Abstractvitreous_humor_rheology_after_ndyag_laser_photo_disruption.pdf

Abstract This work aimed to consider the hazardous side effect of eye floaters treatment with Q-switched Nd:YAG laser on the protein and viscoelastic properties of the vit- reous humor, and evaluate the protective role of vitamin C against laser photo disruption. Five groups of New Zealand rabbits were divided as follows: control group for (n = 3) without any treatment, the second group (n = 9) treated with Q-switched Nd:YAG laser energy of 5 mJ 9 100 pulse delivered to the anterior, middle, and posterior vit- reous, respectively (n = 3 for each). The third group (n = 9) received a daily dose of 25 mg/kg body weight vitamin C for 2 weeks, and then treated with laser as the previous group. The fourth group (n = 9) treated with 10 mJ 9 50 pulse delivered to the anterior, middle, and posterior vitreous, respectively (n = 3 rabbits each). The fifth group (n = 9) received a daily dose of 25 mg/kg body weight vitamin C for 2 weeks, and then treated with laser as the previous group. After 2 weeks of laser treatment, the protein content, refractive index (RI), and the rheological properties of vitreous humor, such as consistency, shear stress, and viscosity, were determined. The results showed that, the anterior vitreous group exposed to of 5 mJ 9 100 pulse and/or supplemented with vitamin C, showed no obvious change. Furthermore, all other treated groups especially for mid-vitreous and posterior vitreous humor showed increase in the protein content, RI and the viscosity of vitreous humor. The flow index remained below unity indicating the non-Newtonian behavior of the vitreous humor. Application of Q-switched Nd:YAG laser should be restricted to the anterior vitreous humor to prevent the deleterious effect of laser on the gel state of the vitreous humor.

Keywords Consistency · Flow index · Refractive index ·

Total protein · Viscosity · Vitamin C

Abu Eleinen, K. G., A. A. Mohalhal, D. A. Ghalwash, A. A. Abdel-Kader, A. A. Ghalwash, I. A. Mohalhal, and A. M. Abdullatif, "Vitrectomy with scleral buckling versus with inferior retinectomy in treating primary rhegmatogenous retinal detachment with PVR and inferior breaks.", Eye (London, England), vol. 32, issue 12, pp. 1839-1844, 2018. Abstract

PURPOSE: To evaluate anatomic and functional outcomes of patients treated with pars plana vitrectomy (PPV) with scleral buckling versus PPV with inferior retinectomy for treatment of cases of primary rhegmatogenous retinal detachment (RRD) associated with proliferative vitreoretinopathy (PVR) and inferior retinal breaks.

METHODS: Retrospective, comparative, interventional, single-center study. Fifty-one eyes of fifty-one patients with primary RRD associated with inferior breaks and PVR grade C1 or more were reviewed over 3 years. Twenty-one eyes underwent PPV with encircling band 360° and thirty eyes underwent PPV with primary inferior retinectomy. The primary outcome was final anatomic success. Secondary outcomes included change in visual acuity, primary anatomical success, the mean number of operations, and incidence of postoperative complications.

RESULTS: Primary anatomical success of 85.7% was achieved in buckle group compared to 83.3% in retinectomy group (p = 0.82). Mean duration of follow-up and mean number of operations was 9.8 ± 2.26 and 9.97 ± 2.44 months; 1.24 ± 0.62 and 1.3 ± 0.75 in buckle group and retinectomy group, respectively, achieving final anatomical success of 95.2% for the buckle group and 90% for the retinectomy group with no statistical significant difference (p = 0.49). Although visual acuity (logMAR) was better in the buckle group in the 1st month, it became nearly equal thereafter during the follow-up period (p = 0.5).

CONCLUSION: Similar anatomical and functional outcomes were achieved by combining PPV with scleral buckle or inferior retinectomy for treatment of primary RRD with PVR and inferior breaks.

Elnahry, A. G., E. M. Sallam, K. J. Guirguis, J. H. Talbet, and A. A. Abdel-Kader, "Vitrectomy for a secondary epiretinal membrane following treatment of adult-onset Coats' disease.", American journal of ophthalmology case reports, vol. 15, pp. 100508, 2019. Abstract

Purpose: To report a case of adult-onset Coats' disease that had worsening of macular edema and progressive macular traction following cryotherapy and repeated intravitreal bevacizumab injections due to formation of a secondary epiretinal membrane which only improved following pars plana vitrectomy and membrane peeling.

Observations: A 35-year-old male presented with diminution of vision in his left eye and was found to have localized telangiectatic retinal vessels and aneurysmal dilatations with massive exudation and cystoid macular edema. He was diagnosed as adult-onset Coats' disease and treated with cryotherapy and a concomitant intravitreal injection of 2.5 mg bevacizumab followed by 3 monthly intravitreal injections of 2.5 mg bevacizumab and a single injection of 4 mg triamcinolone acetonide. Partial obliteration of the telangiectatic vessels and aneurysmal dilatations with improvement in surrounding lipid and fluid exudate was achieved, however, this was associated with progressive worsening of macular edema and macular traction due to formation of an epiretinal membrane which only improved following vitrectomy and membrane peeling. Effect of therapy at each stage was evaluated using visual acuity testing, fundus examination, fundus fluorescein angiography, and optical coherence tomography.

Conclusion and Importance: A secondary epiretinal membrane can develop following treatment of adult-onset Coats' disease and cause traction especially when combining cryotherapy with bevacizumab injections. Vitrectomy in such cases with membrane peeling may result in improvement of anatomical and functional outcomes.

Gramoun, A., M. F. Manolson, J. N. M. Heersche, D. P. Trebec, and S. Y. Mao, "Vitaxin (R), an alphav beta3 blocking antibody, inhibits osteoclastic resorption by decreasing the number of attached osteoclasts.", JOURNAL OF BONE AND MINERAL RESEARCH, vol. 19: AMER SOC BONE & MINERAL RES 2025 M ST, NW, STE 800, WASHINGTON, DC 20036-3309 USA, pp. S154–S154, 2004. Abstract
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Wahba, N. S., R. H. Abdel-Ghany, S. A. Ghareib, M. Abdel-Aal, A. E. Alsemeh, and D. Sabry, "Vitamin D3 potentiates the nephroprotective effects of vildagliptin-metformin combination in a rat model of metabolic syndrome.", Fundamental & clinical pharmacology, vol. 36, issue 2, pp. 306-323, 2022. Abstract

The current study was conducted to investigate the nephroprotective effects of vildagliptin-metformin combination in an experimental model of fructose/salt-induced metabolic syndrome (MetS). A major aim was to evaluate the potential capacity of vitamin D3 to potentiate the pleiotropic nephroprotective effects of vildagliptin-metformin combination. MetS was induced in adult male Wistar rats by adding fructose (10%) to everyday drinking water and salt (3%) to the diet for 6 weeks. Along with the same concentrations of fructose/salt feeding, MetS rats were then treated orally with either vildagliptin (10 mg/kg/day)-metformin (200 mg/kg/day) combination, vitamin D3 (10 μg/kg/day), or the triple therapy for a further 6 weeks. The incidence of MetS was confirmed 6 weeks after fructose/salt consumption, when the rats exhibited significant weight gain, dyslipidemia, hyperuricemia, insulin resistance, hyperinsulinemia, and impaired glucose tolerance. At the end of the 12-week experimental period, MetS rats displayed significantly deteriorated renal function, enhanced intrarenal oxidative stress and inflammation together with exaggerated renal histopathological damages and interstitial fibrosis. The study has corroborated antioxidant, anti-inflammatory, and antifibrotic effects of vildagliptin-metformin combination, vitamin D3, and the triple collaborative therapy, conferring renoprotection in the setting of MetS. Due attention has been paid to the crucial role of dipeptidyl peptidase-4 inhibition and sirtuin-1/5' adenosine monophosphate-activated protein kinase activation as novel therapeutic targets to optimize renoprotection. The apparent potentiating effect, evoked upon coadministration of vitamin D3 with vildagliptin-metformin combination, may provide a cornerstone for further clinical investigations.

Ashour, H., S. M. Gamal, N. B. Sadek, L. A. Rashed, R. E. Hussein, S. S. Kamar, H. Ateyya, M. N. Mehesen, and A. M. Shamseldeen, "Vitamin D Supplementation Improves Uterine Receptivity in a Rat Model of Vitamin D Deficiency: A Possible Role of HOXA-10/FKBP52 Axis.", Frontiers in physiology, vol. 12, pp. 744548, 2021. Abstract

Synchronized uterine receptivity with the time of implantation is crucial for pregnancy continuity. Vitamin D (VD) deficiency has been linked to the failure of implantation. Therefore, we tested the link between the Homeobox transcription factor-10/immunophilin FK506-binding protein 52 (HOXA-10/FKBP52) axis and the uterine receptivity in VD-deficient rats. The effect of VD supplementation at different doses was also investigated. Forty-eight pregnant rats were divided into six groups (eight/group); normal control rats fed with standard chow (control), control rats supplemented with VD (equivalent dose of 400 IU/day) (control-D400). VD-deficient group (DEF) and the three VD deficiency groups with VD supplementation were equivalent to 400, 4,000, and 10,000 IU/day (DEF-D400, DEF-D4000, and DEF-D10000, respectively). The expression levels of HOXA-10/FKBP52, progesterone level, and histological evaluation of decidualization using osteopontin (OSN) and progesterone receptor (PGR) were estimated. An assessment of the uterine contractility was conducted for all rats. This study showed the downregulation of HOXA-10/FKBP52 together with increased amplitude and frequency of the uterine contractility in the DEF group compared to control. VD dose-dependent supplementation restored progesterone/receptor competency, upregulated the expressional response of HOXA-10 and its downstream FKBP52, and improved uterine receptivity and endometrial decidualization at the time of implantation that was documented by increased area% of OSN and the number of implantation beads.

Ashour, H., S. M. Gamal, N. B. Sadek, L. A. Rashed, R. E. Hussein, S. S. Kamar, H. Ateyya, M. N. Mehesen, and A. M. Shamseldeen, "Vitamin D Supplementation Improves Uterine Receptivity in a Rat Model of Vitamin D Deficiency: A Possible Role of HOXA-10/FKBP52 Axis.", Frontiers in physiology, vol. 12, pp. 744548, 2021. Abstract

Synchronized uterine receptivity with the time of implantation is crucial for pregnancy continuity. Vitamin D (VD) deficiency has been linked to the failure of implantation. Therefore, we tested the link between the Homeobox transcription factor-10/immunophilin FK506-binding protein 52 (HOXA-10/FKBP52) axis and the uterine receptivity in VD-deficient rats. The effect of VD supplementation at different doses was also investigated. Forty-eight pregnant rats were divided into six groups (eight/group); normal control rats fed with standard chow (control), control rats supplemented with VD (equivalent dose of 400 IU/day) (control-D400). VD-deficient group (DEF) and the three VD deficiency groups with VD supplementation were equivalent to 400, 4,000, and 10,000 IU/day (DEF-D400, DEF-D4000, and DEF-D10000, respectively). The expression levels of HOXA-10/FKBP52, progesterone level, and histological evaluation of decidualization using osteopontin (OSN) and progesterone receptor (PGR) were estimated. An assessment of the uterine contractility was conducted for all rats. This study showed the downregulation of HOXA-10/FKBP52 together with increased amplitude and frequency of the uterine contractility in the DEF group compared to control. VD dose-dependent supplementation restored progesterone/receptor competency, upregulated the expressional response of HOXA-10 and its downstream FKBP52, and improved uterine receptivity and endometrial decidualization at the time of implantation that was documented by increased area% of OSN and the number of implantation beads.

Ashour, H., S. M. Gamal, N. B. Sadek, L. A. Rashed, R. E. Hussein, S. S. Kamar, H. Ateyya, M. N. Mehesen, and A. M. Shamseldeen, "Vitamin D Supplementation Improves Uterine Receptivity in a Rat Model of Vitamin D Deficiency: A Possible Role of HOXA-10/FKBP52 Axis.", Frontiers in physiology, vol. 12, pp. 744548, 2021. Abstract

Synchronized uterine receptivity with the time of implantation is crucial for pregnancy continuity. Vitamin D (VD) deficiency has been linked to the failure of implantation. Therefore, we tested the link between the Homeobox transcription factor-10/immunophilin FK506-binding protein 52 (HOXA-10/FKBP52) axis and the uterine receptivity in VD-deficient rats. The effect of VD supplementation at different doses was also investigated. Forty-eight pregnant rats were divided into six groups (eight/group); normal control rats fed with standard chow (control), control rats supplemented with VD (equivalent dose of 400 IU/day) (control-D400). VD-deficient group (DEF) and the three VD deficiency groups with VD supplementation were equivalent to 400, 4,000, and 10,000 IU/day (DEF-D400, DEF-D4000, and DEF-D10000, respectively). The expression levels of HOXA-10/FKBP52, progesterone level, and histological evaluation of decidualization using osteopontin (OSN) and progesterone receptor (PGR) were estimated. An assessment of the uterine contractility was conducted for all rats. This study showed the downregulation of HOXA-10/FKBP52 together with increased amplitude and frequency of the uterine contractility in the DEF group compared to control. VD dose-dependent supplementation restored progesterone/receptor competency, upregulated the expressional response of HOXA-10 and its downstream FKBP52, and improved uterine receptivity and endometrial decidualization at the time of implantation that was documented by increased area% of OSN and the number of implantation beads.

Ashour Hend, M., Gamal Sara Mahmoud, Sadek Nermeen Bakr, R. Laila, Hussein Rania Elsayed, Kamar Samaa Samir, Ateyya Hayam, Mehesen Marwa Nagi, and S. E. A. Mohammed, "Vitamin D Supplementation Improves Uterine Receptivity in a Rat Model of Vitamin D Deficiency: A Possible Role of HOXA-10/FKBP52 Axis", Frontiers in Physiology, 2021.
Gheita, T. A., S. Sayed, and H. A. Gheita, "Vitamin D status in rheumatoid arthritis patients: relation to clinical manifestations, disease activity, quality of life and fibromyalgia syndrome. ", Intl J Rheum Dis, issue doi: 10.1111/1756-185X.12426. [Epub ahead of print], 2014.
Gheita, T., S. Sayed, H. Gheita, and S. Kenawy, "Vitamin D status in rheumatoid arthritis patients: relation to clinical manifestations, disease activity, quality of life and fibromyalgia syndrome.", Int J Rheum Dis, vol. 19, issue 3, pp. 294-9, 2016.
Gheita, T. A., S. Sayed, H. A. Gheita, and S. A. Kenawy, "Vitamin D status in rheumatoid arthritis patients: relation to clinical manifestations, disease activity, quality of life and fibromyalgia syndrome.", International journal of rheumatic diseases, vol. 19, issue 3, pp. 294-9, 2016. Abstract

AIM: To assess vitamin D levels in rheumatoid arthritis (RA) patients and to find their relation to clinical parameters, fibromyalgia syndrome (FMS), quality of life (QoL) and disease activity.

METHODS: The study included 63 RA patients and 62 controls. Clinical examination and laboratory investigations were performed. For patients, the Disease Activity Score (DAS-28), QoL index, Health Assessment Questionnaire II (HAQ II) and Modified Larsen score were calculated. 25-OH-vitamin D was measured in patients and controls.

RESULTS: The patients' mean age was 41.59 ± 9.69 years and disease duration 5.89 ± 3.67 years. The level of vitamin D in RA patients was significantly lower (23.11 ± 12.71 ng/mL) than that in the controls (32.59 ± 13.06 ng/mL) (P = 0.005) being deficient in 50.8%, insufficient in 23.8% and normal in 25.4%. The RA patients with FMS (n = 33) had significantly lower levels of vitamin D (19.08 ± 10.59 ng/mL) than those without (27.55 ± 13.51 ng/mL) (P = 0.008). The difference was significant on comparing those receiving hydroxychloroquine (17.39 ± 7.84 ng/mL) to those not (31.85 ± 13.85 ng/mL) (P < 0.001). Vitamin D significantly correlated with QoL index (r = 0.58, P < 0.001) and negatively with HAQ II (r = -0.36, P = 0.004) and BMI (r = -0.39, P = 0.001).

CONCLUSION: Special attention is required regarding vitamin D levels in RA patients with FMS and decreased QoL. Vitamin D should be corrected and supplementation considered among the RA management armamentarium.

Garf, K. E., A. E. Garf, huda marzouk, yomna farag, and L. Rashed, "Vitamin D status in Egyptian patients with juvenile-onset systemic lupus erythematosus", Rheumatology International, 2015.
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