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Gaber, A. A., M. Sobhy, A. Turky, H. G. Abdulwahab, A. A. Al-karmalawy, M. A. Elhendawy, M. M. Radwan, E. B. Elkaeed, I. M. Ibrahim, H. S. A. Elzahabi, et al., "Discovery of new 1H-pyrazolo[3,4-]pyrimidine derivatives as anticancer agents targeting EGFRWT and EGFRT790M.", Journal of enzyme inhibition and medicinal chemistry, vol. 37, issue 1, pp. 2283-2303, 2022. Abstract

New 1-pyrazolo[3,4-d]pyrimidine derivatives were designed and synthesised to act as epidermal growth factor receptor inhibitors (EGFRIs). The synthesised derivatives were assessed for their anti-proliferative activities against A549 and HCT-116 cancer cells. Compounds and showed potent anti-proliferative activities. Compound was the most promising member with IC values of 8.21 and 19.56 µM against A549 and HCT-116, respectively. Compounds and were evaluated for their kinase inhibitory activities against wild EGFR (EGFR). Compound was the most potent member showing an IC value of 0.016 µM. In addition, compound showed noticeable activity against mutant EGFR (EGFR) (IC = 0.236 µM). Flow cytometric analyses revealed that compound is a good apoptotic inducer and can arrest the cell cycle at S and G2/M phases. Furthermore, it produced an 8.8-fold increase in BAX/Bcl-2 ratio. Molecular docking studies were carried out against EGFR and EGFR.

Gaber, N. M., Z. A.Halim, and E. A. W. Khalil, "Self perceived interpersonal competencies among schizophrenic patients", Journal of American Science, 2014.
Gaber, T., G. Ismail, A. Anter, M. Soliman, M. Ali, N. Semary, A. E. Hassanien, and V. Snasel, "Thermogram breast cancer prediction approach based on Neutrosophic sets and fuzzy c-means algorithm", Engineering in Medicine and Biology Society (EMBC), 2015 37th Annual International Conference of the IEEE: IEEE, pp. 4254–4257, 2015. Abstract
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Gaber, H. M., G. E. H. Elgemeie, S. A. Ouf, and S. M. Sherif, "Heterocyclic synthesis with 4-hydrazinopyridothienopyrimidines: Synthesis of pyridothienotriazolopyrimidines and heterocyclylpyridothienopyrimidines with biological interest", Heteroatom Chemistry, vol. 16, no. 4: Wiley Online Library, pp. 298–307, 2005. Abstract
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Gaber, H. M., Z. A. Muhammad, S. M. Gomha, T. A. Farghaly, and M. C. Bagley, "Recent Synthetic Approaches to N,N-Dimethyl-β-Ketoenamines", Current of Organic chemistry, vol. 21, issue 21, pp. 2168 - 2195, 2017.
Gaber, G. A., S. A. Abolkassem, O. A. El Kady, M. Tash, and L. Z. Mohamed, "ANOVA and DOE of comparative studies of Cu/Mn effect on corrosion features of CoCrFeNi high entropy alloy immersed in different acidic media", Chemical Papers, vol. 76, pp. 1675–1690, 2022.
Gaber, W., A. S. Hassen, I. I. Abouleyoun, and Z. O. Nawito, "Impact of smoking on disease outcome in ankylosing spondylitis patients", The Egyptian Rheumatologist , vol. 37, Cairo, Cairo University, pp. 185–189, 2015.
Gaber, Y. H., and H. M. Abdelsalam, "A Multi-Objective Optimization Algorithm for the Integrated Product Line Selection and Supply Chain Configuration Problem With Quality Considerations", 10th IEEE International Conference on Service Operations and Logistics, and Informatics (IEEE SOLI 2015), Tunisia , 15 November, 2015.
Gaber, Y., U. T?rnvall, M. A. Kumar, M. A. Amin, and R. Hatti-Kaul, "HPLC-EAT (Environmental Assessment Tool): A tool for profiling safety, Health and Environmental Impacts of Liquid Chromatography Methods", Green Chemistry, 2011. Abstract

A simple and efficient approach for profiling the greenness of high performance liquid chromatography (HPLC) methods is presented. This environmental assessment tool (EAT) takes into consideration the environmental, health and safety issues for all solvents involved in the chromatographic method, and calculates a total score that can be used for comparison of the greenness of different methods. A software, HPLC-EAT, has been designed to facilitate the calculation and can be downloaded free of charge at http://www.biotek.lu.se/hplc-eat/. HPLC-EAT was successfully applied for a set of different HPLC methods from the literature, including both analytical and preparative chromatography. The performance of the tool was validated and it was further combined with another free software Eco-solvent tool to perform life cycle assessments of waste disposal options of distillation or incineration. HPLC-EAT can be routinely used in method development to calculate the greenness beside the conventional standards of accuracy, robustness and reproducibility.

Gaber, G. A., L. Z. Mohamed, and A. Abdelfatah, "Study the corrosion issues on galvanized steel induced in water tanks", Chemical Papers, vol. 9, issue 1, pp. 1-11, 2023. 2023_study_the_corrosion_issues.pdf
Gaber, W., G. S. Azkalany, T. A. Gheita, A. Mohey, and R. Sabry, "Clinical significance of serum interleukin-6 and- 174 G/C promoter polymorphism in Rheumatoid arthritis patients", The Egyptian Rheumatologist, vol. 35, no. 2: Elsevier, pp. 107–113, 2013. Abstract
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Gaber, Y. H., I. A. El-Khodary, and H. M. Abdelsalam, "A Model Review on Joint Optimization of Part Quality Inspection Planning, Buffer Allocation, and Preventive Maintenance in SMMS", Journal of Advanced Manufacturing Systems, vol. 22, no. 03, pp. 667-691, 2023. AbstractWebsite

In serial multi-stage manufacturing systems (SMMS), optimization of part quality inspection planning (PQIP), buffer allocation problem (BAP), and preventive maintenance (PM), individually and jointly, is attracting researchers’ attention. The model formulation for complicated manufacturing systems and the previously mentioned joint decisions is very beneficial given the interdependencies between the various manufacturing functions. As a result, this paper evaluates the literature on joint optimization of the multi-stage serial production system. The literature is classified based on the decision variables basis to represent each manufacturing function [inspection sample size and allocation (PQIP), buffer sizing and allocation (BAP), and preventive maintenance scheduling (PM)], and a general example model is presented in each classification, with a summary of recent studies, solution methods, research gaps, and future research recommendations. In the integrated models, almost all the studies considered only two functions, with that it is worth noting that research into the optimization of over two functions is still in its beginning. Furthermore, most studies neglected many of the real industrial settings that should also be integrated into the model. And finally, there was no specific solution technique recommended in the literature, yet a general simulation optimization method was used to generate and evaluate the combinatorial complex joint models.

Gaber, W., S. Sayed, Y. Ezzat, H. Khalil, and T. W. Kassem, "Comparative study of kidney affection in SLE patients with and without antiphospholipid syndrome", The Egyptian Rheumatologist , vol. 34, pp. 51-57, 2012. 1-s2.0-s1110116412000026-main.pdf
Gaber, W., A. Moghazy, M. Niazy, and H. K. Salem, "Risk factors for sexual dysfunction in Egyptian patients with rheumatoid arthritis and its relation to disease activity", The Egyptian Rheumatologist, pp. 1-4, 2017.
Gaber, E. I., A. S. EL-HASSANIN, H. H. Hassona, and A. M. KHALIFA, "Chemical and mineralogical properties of some Toshka soils", J. of Agricultural Sci., Mansoura University, Egypt, vol. 30, no. 4, pp. 2293-2313, 2005. Abstract
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Gaber, A., M. F. Taher, and M. A. Wahed, "A pilot study on automated quantitative grading of facial functions", Vibroengineering PROCEDIA, Dubai, pp. 109-115, 2020.
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