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Honeybul, S., K. Ho, C. R. P. Lind, G. R. Gillett, J. P. Dreier, A. Demertzi, A. Soddu, F. Gomez, L. Heine, and C. di Perri, "Abstracts from The 11th Symposium of the International Neurotrauma Society March 19–23, 2014 Budapest, Hungary", Journal of Neurotrauma, vol. 31, issue 5: Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA, pp. A-1-A-73, 2014. Abstract
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Honeybul, S., K. Ho, C. R. P. Lind, G. R. Gillett, J. P. Dreier, A. Demertzi, A. Soddu, F. Gomez, L. Heine, and C. di Perri, Abstracts from The 11th Symposium of the International Neurotrauma Society March 19–23, 2014 Budapest, Hungary, , vol. 31, issue 5: Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA, pp. A - 1, 2014. Abstract
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El-Zawawy, M. A., "Abstraction Analysis and Certified Flow and Context Sensitive Points-to Relation for Distributed Programs", 12th International Conference Computational Science and Its Applications, ICCSA 2012, Salvador de Bahia, Brazil, June 18-21, 2012, Proceedings, Part IV, ICCSA (4), Lecture Notes in Computer Science, vol. 7336: Springer, pp. 83-99, 2012. AbstractAbstraction Analysis and Certified Flow and Context Sensitive Points-to Relation for Distributed Programs.pdf

This paper presents a new technique for pointer analysis of distributed programs executed on parallel machines with hierarchical memories. One motivation for this research is the languages whose global address space is partitioned. Examples of these languages are Fortress, X10, Titanium, Co-Array Fortran, UPC, and Chapel. These languages allow programmers to adjust threads and data layout and to write to and read from memories of other threads. The techniques presented in this paper have the form of type systems which are simply structured. The proposed technique is shown on a language which is the while langauge enriched with basic commands for pointer manipulations and also enriched with commands vital for distributed execution of programs. An abstraction analysis that for a given statement calculates the set of function abstractions that the statement may evaluate-to is introduced in this paper. The abstraction analysis is needed in the proposed pointer analysis. The mathematical soundness of all techniques presented in this paper are discussed. The soundness is proved against a new operational semantics presented in this paper. Our work has two advantages over related work. In our technique, each analysis result is associated with a correctness proof in the form of type derivation. The hierarchical memory model used in this paper is in line with the hierarchical character of concurrent parallel computers.

Kassem, L., L. Fattet, J. Lopez, G. Thibault, E. Lavergne, S. Chabaud, N. Carrabin, N. Chopin, T. Bachelot, and G. Gillet, Abstract P4-11-24: TIF1 [gamma] interacts with the TGFβ1/SMAD4 signaling leading to poorer outcome in operable breast cancer, : American Association for Cancer Research, 2015. Abstract
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Rivera, S., C. Vens, P. Maingon, A. S. Govaerts, E. Shash, D. Lacombe, W. Grant, and V. Grégoire, "Abstract C220: Combining novel targeted therapies and radiotherapy: A challenge to overcome.", Molecular Cancer Therapeutics, vol. 12, no. 11 Supplement: AACR, pp. C220–C220, 2013. Abstract
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Kato, S., S. Roujol, F. Delling, S. Akhtari, J. Jang, T. Basha, S. Berg, K. Kissinger, B. Goddu, and W. Manning, "Abstract 14783", Circulation, vol. 132, issue Suppl_3, pp. A14783, 2015. Abstract
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Mansour, W. Y., N. V. Bogdanova, U. Kasten-Pisula, T. Rieckmann, S. Köcher, K. Borgmann, M. Baumann, M. Krause, C. Petersen, H. Hu, et al., "Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma.", Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, vol. 106, issue 1, pp. 147-54, 2013 Jan. Abstract

BACKGROUND: Cellular and clinical sensitivity to ionizing radiation (IR) is determined by DNA double-strand breaks (DSB) repair. Here, we investigate the molecular mechanism underlying the extreme response of a head and neck tumor case (SKX) to standard radiotherapy.

METHODS: Immunofluorescence (IF) was used for the assessment of DSB repair, Western blot and real-time PCR for protein and mRNA expression, respectively.

RESULTS: SKX cells exhibited a pronounced radiosensitivity associated with numerous residual γ-H2AX foci after IR. This was not associated with lacking canonical repair proteins. SKX cells did not express any ATM protein. Accordingly, immunoblotting revealed no ATM kinase activity toward substrates such as p-SMC1, p-CHK2 and p-KAP1. Sequencing of all 66 exons of ATM showed no mutation. ATM mRNA level was moderately reduced, which could be reverted by 5'-Aza-C treatment but without restoring protein levels. Importantly, we demonstrated a post-transcriptional regulation in SKX cells via 6-fold enhanced levels of miR-421, which targets the 3'-UTR of ATM mRNA. Transfection of SKX cells with either anti-miR-421 inhibitor or a microRNA-insensitive ATM vector recovered ATM expression and abrogated the hyper-radiosensitivity.

CONCLUSION: This is the first report describing microRNA-mediated down-regulation of ATM leading to clinically manifest tumor radiosensitivity.

Mansour, W. Y., N. V. Bogdanova, U. Kasten-Pisula, T. Rieckmann, S. Kocher, K. Borgmann, M. Baumann, M. Krause, C. Petersen, H. Hu, et al., "Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma", Radiother Oncol, 2012/12/04, vol. 106, no. 1, pp. 147-54, Jan, 2013. Abstractmansour_2013.pdfWebsite

BACKGROUND: Cellular and clinical sensitivity to ionizing radiation (IR) is determined by DNA double-strand breaks (DSB) repair. Here, we investigate the molecular mechanism underlying the extreme response of a head and neck tumor case (SKX) to standard radiotherapy. METHODS: Immunofluorescence (IF) was used for the assessment of DSB repair, Western blot and real-time PCR for protein and mRNA expression, respectively. RESULTS: SKX cells exhibited a pronounced radiosensitivity associated with numerous residual gamma-H2AX foci after IR. This was not associated with lacking canonical repair proteins. SKX cells did not express any ATM protein. Accordingly, immunoblotting revealed no ATM kinase activity toward substrates such as p-SMC1, p-CHK2 and p-KAP1. Sequencing of all 66 exons of ATM showed no mutation. ATM mRNA level was moderately reduced, which could be reverted by 5'-Aza-C treatment but without restoring protein levels. Importantly, we demonstrated a post-transcriptional regulation in SKX cells via 6-fold enhanced levels of miR-421, which targets the 3'-UTR of ATM mRNA. Transfection of SKX cells with either anti-miR-421 inhibitor or a microRNA-insensitive ATM vector recovered ATM expression and abrogated the hyper-radiosensitivity. CONCLUSION: This is the first report describing microRNA-mediated down-regulation of ATM leading to clinically manifest tumor radiosensitivity.

Petit, J. Y., M. Rietjens, C. Garusi, A. Giraldo, F. De Lorenzi, P. Rey, E. C. Millen, B. P. da Silva, R. Bosco, and O. Youssef, "Abdominal complications and sequelae after breast reconstruction with pedicled TRAM flap: is there still an indication for pedicled TRAM in the year 2003?", Plastic and reconstructive surgery, vol. 112, no. 4: LWW, pp. 1063–1065, 2003. Abstract
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Elfishawi, M. M., B. R. Sakr, M. H. El-Arousy, A. K. Hatw, A. N. AbdulKarim, A. B. Tammam, A. N. Kotp, M. E. Hamed, I. E. Genedy, and E. D. El Desouky, AB1031 Rheumatoid Arthritis, A Single-Center Egyptian Experience, : BMJ Publishing Group Ltd, 2016. Abstract
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Gomaa, M. M., Hussain S. A., E. - D. E. A., Bayoumi, and M. M. Gobashy, "A.C. Electrical properties of kaolinite under pressure- pseudo random network modeling", 63th Conference and technical exhibition of the European Association of Geoscientists and Engineers (EAGE), Session P054, Amsterdam, The Netherlands. , 2001.
Thielebein, J., K. K. Poland, N. M. El Sawi, N. S. Geweely, S. Qusti, M. Mohamed, A. Kamel, C. Merera, and A. Abebe, "A. Beker, TA Gipson, R. Puchala, AR Askar, K. Tesfai, GD Detweiler, A. Asmare and AL Goetsch (USA)......", J. Appl. Anim. Res, vol. 38: Taylor & Francis, pp. 279–285, 2010. Abstract
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Kim, D. I., K. H. Lee, A. A. Gabr, G. E. Choi, J. S. Kim, S. H. Ko, and H. J. Han, "A$\beta$-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis", Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, vol. 1863, no. 11: Elsevier, pp. 2820–2834, 2016. Abstract
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Kim, D. I., K. H. Lee, A. A. Gabr, G. E. Choi, J. S. Kim, S. H. Ko, and H. J. Han, "A$\beta$-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis", Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, vol. 1863, no. 11: Elsevier, pp. 2820–2834, 2016. Abstract
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Brooks, M. J., J. L. Sedillo, N. Wagner, W. Wang, A. S. Attia, H. Wong, C. A. Laurence, E. J. Hansen, and S. D. Gray-Owen, "Moraxella catarrhalis binding to host cellular receptors is mediated by sequence-specific determinants not conserved among all UspA1 protein variants", Infection and immunity, 2008/08/06, vol. 76, no. 11, pp. 5322-9, Nov, 2008. AbstractWebsite

The Moraxella catarrhalis ubiquitous surface proteins (UspAs) are autotransporter molecules reported to interact with a variety of different host proteins and to affect processes ranging from serum resistance to cellular adhesion. The role of UspA1 as an adhesin has been confirmed with a number of different human cell types and is mediated by binding to eukaryotic proteins including carcinoembryonic antigen-related cellular adhesion molecules (CEACAMs), fibronectin, and laminin. A distinct difference in the ability of prototypical M. catarrhalis strains to adhere to CEACAM-expressing cell lines prompted us to perform strain-specific structure-function analyses of UspA1 proteins. In this study, we characterized CEACAM binding by a diverse set of UspA1 proteins and showed that 3 out of 10 UspA1 proteins were incapable of binding CEACAM. This difference resulted from the absence of a distinct CEACAM binding motif in nonadhering strains. Our sequence analysis also revealed a single M. catarrhalis isolate that lacked the fibronectin-binding motif and was defective in adherence to Chang conjunctival epithelial cells. These results clearly demonstrate that UspA1-associated adhesive functions are not universally conserved. Instead, UspA1 proteins must be considered as variants with the potential to confer both different cell tropisms and host cell responses.

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Mahmoud B, G. Ghonemy, and M. & Fawaz, ":" Assessment Of Nutritional Learning Need Of The Mother During Postpartum Period",", The Medical Journal Of Cairo University ,December, vol. ,Vol.82, issue No.2., 2014.
Eldebss, T. M. A., K. H. Mahmoud, K. S. Essa, and O. Ghofrane, : The Magnetosphere, , 2022. chapter.pdf
Refai, M., El-Sanousi, S., Gergis, S., S. Abdel-Hamid, and M. Hashad, ": Experimental afla- and ochratoxicosis in chickens vaccinated with fowl cholera vaccine. I. Impairment of cell-mediated immunity and phagocytic function ", J. Egypt. Vet. Med. Ass., vol. 53, pp. 227-233, 1993. exper._afla_and_ochra_i.pdf
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El-Shabrawi, M. H., S. Omran, S. Wageeh, M. Isa, Sawsan Okasha, Mona Isa, N. A. Mohsen, O. Zekry, E. Gamal, H. M. El-karaksy, and others, "99mTechnetium-macroaggregated albumin perfusion lung scan versus contrast enhanced echocardiography in the diagnosis of the hepatopulmonary syndrome in children with chronic liver disease", European journal of gastroenterology & hepatology, vol. 22, no. 8: LWW, pp. 1006–1012, 2010. Abstract

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Nasr, H., H. Mustafa, A. Fawzy, E. I. Ghoniemy, and M. Mostafa., "99mTC-Tetrofosmin Brain SPECT Versus CT And MRI In Assessment Of Outcome Of Treatment Of Brain Tumors", 3rd Annual International Meeting of The Egyptian Society of Nuclear Medicine Specialists , Sharm El-sheik, Egypt, 16 March, 2002.
Atta, N. F., Y. M. Ahmed, M. H. BinSabt, and A. Galal, "9- Hematite Nanoparticles/Ionic Liquid Crystal/Graphene–Based Nanocomposite Electrochemical Sensor for Sensitive Determination of Antipsychotic Drug", J of the electrochemical society, vol. 163, issue 14, pp. B659-B666 , 2016.