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Gaafar, T., R. E. Hawary, A. Osman, W. Attia, H. Hamza, K. Brookmayer, and O. Osman, "Comparative characteristics of amniotic membrane, endometrium and ovarian derived mesenchymal stem cells: A role for amniotic membrane in stem cell therapy", Middle East Fertility and Sterility journal, vol. 19, pp. 156-170, 2014.
Gaafar, K., H. el Nazer, S. Salama, and S. el Batran, "Study on the possible interaction between an ace inhibitor, a diuretic and an anti-inflammatory drug in normal rats.", Bollettino chimico farmaceutico, vol. 134, issue 4, pp. 216-219, 1995. Abstractstudy_on_the_possible_interaction.pdf

Captopril was effective in the long term reduction of serum sodium and aldosterone in normotensive rats, the addition of HCT produced a further decrease in serum sodium and was also useful in preventing hypokalemia produced by HCT. On the other hand, the concurrent therapy with Diclofenac attenuated the hypotensive effect of Captopril and HCT, it was observed that to combine Diclofenac with captopril was more beneficial as regards the metabolic parameters.

Gaafar, K., and S. R. Fahmy, "Effects of Laboratory Animal Science Training on Scientists' Attitudes and Practice in Egypt. ", Journal of the American Association for Laboratory Animal Science, vol. 57, issue 6, pp. 1-3, 2018. jaalas_training.pdf
Gaafar, T. M., H. A. A. Rahman, W. Attia, H. S. Hamza, K. Brockmeier, and R. E. E. Hawary, "Comparative characteristics of endothelial-like cells derived from human adipose mesenchymal stem cells and umbilical cord blood-derived endothelial cells", Clinical and Experimental Medicine, vol. 14, issue 2, pp. 177-184, 2013.
Gaafar, R., H. Khaled, Y. A. Sallam, H. Shafik, F. A. Aboulkassem, and M. Emara, "Impact of relatively new chemotherapeutic agents on the outcome of Egyptian patients with advanced malignant pleural mesothelioma", Forum of Clinical Oncology, vol. 5, issue 1: De Gruyter Open, pp. 29-36, Submitted. Abstract
Gaafar, T., S. Shawky, H. Hamza, and R. E. Hawary, "he role of angiotensin II incardiomyogenic differentiation of humanadipose tissue-derived mesenchymal stem cells ", Comparative Clinical Pathology ISSN 1618-56 DOI 10.1007/s00580-014-2001-z, 2014. 10.1007_s00580-014-2001-z.pdf
Gaafar, K., and H. M. taha, "Blood indices in relation to methyl alcohol toxicity in rats", the egyptian medical journal, vol. 6, pp. 595-601, 1989. Abstractblood_indices.pdf

The effect of methyl alcohol toxicity on some blood indices in adult male rats were studied. Male albino rats were injected intraperitoneally with absolute methanol (4 ml/kg body weight). The data revealed a highly significant decrease in total erythrocyte and leucocyte counts concomitant with an increase in hematocrit, hemoglobin, mean cell volume and mean cell hemoglobin following methanol administration. It was concluded that blood indices, in particular mean corpuscular volume, may be used as a test to verify meyhanol toxicity.

Gaafar, T., M. O. F. Hanna, O. Osman, H. Amr, and A. Osman, "Evauation of cytokines in follicular fluid and their effect on fertilization and pregnancy outcome. ", Immunological Investigations, 2014; 43(6): 572–584 DOI: 10.3109/08820139.2014.901974, 2014. paper_in_immunological_investigation.pdf
Gaafar, A., and T. Marei, "Intra-Operative Transesophageal Echocardiography In Rheumatic Mitral Valve Surgery : Diagnostic Accuracy and Predictability of Repair .", Journal of The Egyptian Society of Cardio-Thoracic Surgery, vol. 21, issue 3, pp. 73-82, 2013.
Gaafar, K. M., H. taha, and J. seid, "Beneficial effects of capozide on carbohydrate and lipid metabolism", Proceedings of the egyptian Academy of Sciences, vol. 46, pp. 41-56, 1996. Abstractbeneficial_effects.pdf

capozide was administered in a dose of 1.012 mg/200g rat body weight once a day for 4 weeks to normal and diabetic rats. It had no effects on serum potassium urea or creatinine. No increase in lipid concentration to negate its beneficial hypotensive effect, was noted. Form oral glucose tolerance test, it was calculated that the drug improved glucose tolerance concomitant with the increased beta cell function and peripheral insulin response.
The interaction between the two components of capozide, captopril an angiotensin converting enzyme inhibitor, and hydrochlorothiazide, a diuretic, is discussed in regards to carbohydrate and lipid homeostasis.

Gaafar, K., N. K. Elsayed, L. A. R. Khalek, and S. H. Caram, "Changes in some serum and histoenzymes in methyl alcohol hepatotoxicity in rats", the egyptian journal of histology, vol. 14, pp. 385-393, 1991. Abstractchanges_in_some_serum.pdf

Male albino rats were given 2,4 and 6% methyl alcohol solution as drinking water for 4 weeks. Liver tissue was examined for histopathologic and histochemical changes in some liver enzymes. Changes in some serum enzymes and glucose level were also assayed. The histopathologic changes in the liver were in the form of venous congestion, increased influx of inflammatory cells, bile duct proliferation, fatty degeneration and necrosis of liver parenchyma.

Succinic dehydrogenase (SDH) and membrane adenosine triphosphatase (ATPase) activities increased whereas lactate dehydrogenase (LDH) activity decreased indicating enhanced aerobic glycolysis and active phosphorylation and inhibition of anaeobic glycolysis. This was accompanied by hyperglycaemia on the first week followed by drop of glucose to normal value sug-gesting its increased utilization as energy source to offset the effects of the toxin.

Acid phosphatase (ACP) activity increased in the liver parenchyma. Alkaline phosphatase (ALP) was also activated while membrane ATPase was inhibited revealing disturbances in membrane transport processes. Liver dysfunction was also confirmed by increased activity of the serum enzymes gamma glutamyl transferase (GGT), glutamic oxaloacetate transaminase (GOT), glutamic pyruvate transaninase (GPT) and LDH.

Gaafar, R., M. R. Hamza, A. A. Rabia, H. Khaled, I. Osman, H. Al-Zawahry, N. M.Ali, M. A. Saber, M. Al-Serafi, and N. G. A. Moula, "Evaluation of recombinant alpha 2B interferon and 5-fluorouracil in advanced and metastatic colorectal carcinoma. ", J. Egypt. Nat. Cancer Inst., vol. 6, issue 4, pp. 741 - 750, 1994.
Gaafar, T. M., R. E. Hawary, A. Osman, W. Attia, H. Hamza, K. Brockmeier, and O. M. Osman, "Comparative characteristics of amniotic membrane, endometrium and ovarian derived mesenchymal stem cells: A role for amniotic membrane in stem cell therapy", Middle East Fertility Society Journal, vol. 19, pp. 156-170, 2014.
Gaafar, T., F. abdelraouf, and M. o Brien, "* Focused molecular analysis of smallcell lung cancer: feasibility in routine clinicalpractice. ", BMC Res Notes (2015), issue 8:688 DOI 10.1186/s13104-015-1675-x, 2015. sclc_paper_fatma.pdf
Gaafar, K. M., M. I. Khedr, S. A. Bashandy, O. A. Sharaf, and S. R. el-Zayat, "Effect of chloroquine on glucose metabolism", Arzneimittel-Forschung, vol. 52, issue 5, pp. 400-6, 2002. Abstracteffect_of_chloroquine.pdf

The long- and short-term effects of chloroquine (CAS 54-05-7) on glucose metabolism in rats were assessed. The long-term chronic chloroquine administration (5 and 10 mg/kg b.w. 6 days a week for 6 months) caused a decrease in serum glucose, insulin, calcium, potassium and protein levels, while the glucagon level increased. The short-term acute effect of chloroquine administration (10 mg/kg b.w. 6 days for one week) caused an improvement in glucose tolerance as shown by the decrease in glucose and insulin curves after an oral glucose tolerance test. This was accompanied by an increase in insulin activity, corrected insulin response, and glucose tolerance parameter and a decrease in glucose and insulin areas. Lactate dehydrogenase and glucose-6-phosphate dehydrogenase activities were increased, too, indicating an increase which provides the needed energy for overcoming the injurious effect of chloroquine.

Gaafar, K., "Superoxide dismutase and glutathione in methanol and ethanol treated rats", journal of the egyptian german society of zoology, vol. 15 (A), pp. 461-471, 1994. Abstractsuperoxide_dismutase.pdf

The long term (6 Weeks) effect of both methanol (2 ml/kg) and ethanol (2 ml/kg) on GSH and SOD activities in rats was studied. Blood SOD and GSH activity declined sharply (1st week), then started to increase gradually. Liver GSH was seen to increase significantly (4 and 6 weeks post treatment). This was attributed to their swift usage in scavenging the free radical produced from the metabolism of the alcohols, and their protective response whereby an increase in their synthesis occurs.

Gaafar, R. M., M. M. Hussein, N. M. A. Allahloubi, A. A. M. Warith, W. A. A. Allah, S. E. Salem, and E. A. M. Salam, "Toxicity and prediction of survival benefit with metronomic chemotherapy in metastatic breast cancer.", Journal of Clinical Oncology, vol. 32, issue 15_suppl, pp. 1045-1045, 2014.
Gaafar, R. M., V. F. Surmont, G. V. Scagliotti, R. V. J. Klaveren, D. Papamichael, J. J. Welch, B. Hasan, and V. T. P. andJan van Meerbeeck, "A Double-Blind, Randomised, Placebo-Controlled Phase III Intergroup Study of Gefitinib in Patients with Advanced NSCLC, non Progressing After First Line Platinum-Based Chemotherapy (EORTC 08021/ILCP 01/03)", European Journal of Cancer, 2011. Abstract

Background: EORTC study 08021/ILCP 01/03 evaluated the role of consolidation gefitinib, an oral tyrosine kinase inhibitor (TKI), administered in patients with advanced non-small cell lung cancer (NSCLC), not progressing following standard 1st-line chemotherapy.

Gaafar, T., S. Shawky, W. Attia, H. Hamza, and R. E. Hawary, "The role of angiotensin II in cardiomyogenic differentiation of human adipose tissue-derived mesenchymal stem cells", Comparative Clinical Pathology, vol. 24, issue 4, pp. 879-885, 2015.
Gaafar, T. M., M. O. F. Hanna, M. R. Hammady, H. M.Amr, O. M. Osman, A. Nasef, and A. Osman, "Evaluation of cytokines in follicular fluid and their effect on fertilization and pregnancy outcome", Immunological Investigations, vol. 43, issue 6, pp. 572-584, 2014.
Gaafar, K., F. K.I, T. H.M, and kishta O.A, "Methanol and glucose homeostasis", the egyptian journal of medical sciences, vol. 15, pp. 689-698, 1994. Abstractmethanol_and_glucose.pdf

Glucose tolerance curve, glycogen and the calculated glucose tolerance (GT), peripheral insulin activity (A value), beta cell function (CIR) and glucose and insulin areas were studied in rats intoxicated with methanol. The study revealed that a sublethal dose of methanol (2 ml/kg b.wt) increases glucose consumption at the same time having no effect on insuline secretion, While the continued administration of methanol depletes glycogen due to its breakdown to restore glucose levels to normal values. The lethal dose (6 ml/kg b.wt) cause insuline resistance.

Gaafar, S. A., K. H. Mahmoud, S. I. Bannan, and M. F. H. Abd Elkader, Biophysical Studies of γ-irradiate Glycogen/PVA blends doped with Dye, , Giza, Cairo University, 2007.
Gaafar, T., O. Osman, A. Osman, W. Attia, H. Hamza, and E. R. Hawary, "Gene expression profiling of endometrium versus bone marrow-derived mesenchymal stem cells: upregulation of cytokine genes.", Molecular and Cellular Biochemistry, vol. 395, issue 1-2, pp. 29-34, 2014.