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Gruber-Rouh, T., N. N. N. Naguib, M. Beeres, P. Kleine, T. J. Vogl, V. Jacobi, M. Alsubhi, and N. A. Nour-Eldin, "CT-guided hook-wire localisation prior to video-assisted thoracoscopic surgery of pulmonary lesions.", Clinical radiology, vol. 72, issue 10, pp. 898.e7-898.e11, 2017 Oct. Abstract

AIM: To assess the feasibility, safety, and efficacy of computed tomography (CT)-guided pulmonary nodule localisation using a hooked guide wire before video-assisted thoracoscopic surgery (VATS).

MATERIALS AND METHODS: The study included 79 patients with a history of malignancies outside the lung associated with pulmonary nodules. Mean lesion size was 0.7 cm (range 0.5-1.8 cm) and the mean lesion distance to the pleural surface was 1.5 cm (range 0.2-5 cm). All lesions (n=82) were marked with a 22-G hook wire. The technique was designed to insert the tip of the hook wire within or maximally 1 cm from the edge of the lesion. The Mann-Whitney U-test was used for univariate analyses and Fisher's exact test for categorical values.

RESULTS: The hooked guide wire was positioned successfully in all 82 pulmonary nodules within mean time of 9 minutes (8-20 minutes, SD: 2.5 minutes). The procedure time was inversely proportional to the size of the lesion (Spearman correlation factor 0.7). Minimal pneumothoraces were observed in five patients (7.6%). Pneumothorax was not correlated to the histopathology of the pulmonary nodules (p>0.09). Focal perilesional pulmonary haemorrhage developed in four patients (5%). Both haemorrhage and pneumothorax were significantly correlated to lesions <10 mm (p=0.02 and 0.01 respectively). The volume of resected lung tissue was significantly correlated to lesions of increased distance from the pleural surface ≥2.5 cm in comparison to lesions of <2.5 cm from the pleural surface.

CONCLUSION: CT-guided pulmonary nodule localisation prior to VATS could enable safe, accurate surgical guidance for the localisation of small pulmonary nodules.

Gruber-Rouh, T., N. N. N. Naguib, M. Beeres, B. Kaltenbach, T. J. Vogl, and N. - E. A. Nour-Eldin, "Transarterial Chemoembolization (TACE) as A Palliative Treatment Option for Liver Metastases from Non-Small Cell Lung Cancer (NSCLC)", International Journal of Radiology and Imaging Technology, vol. 2, issue 3, pp. 19-25, 2016.
Gruber-Rouh, T., A. Thalhammer, T. Klingebiel, N. - E. A. Nour-Eldin, T. J. Vogl, K. Eichler, N. Naguib, and M. Beeres, "Computed tomography-guided biopsies in children: accuracy, efficiency and dose usage", Italian Journal of Pediatrics, pp. 43-44, 2017.
GRUJlĆ, L. J. T., M. Darwish, and J. Fantin, "Coherence, vector Liapunov functions and large-scale power systems", International Journal of Systems Science, vol. 10, no. 3: Taylor & Francis, pp. 351–362, 1979. Abstract
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GS, H., R. DEA, A. EA, R. RH, S. MA, and N. YM, "New pyrazole derivatives: Synthesis, anti-inflammatory activity, cycloxygenase inhibition assay and evaluation of mPGES", European journal of medicinal chemistry, vol. 171, pp. 332-342, 2019.
GS, H., R. DEA, N. YM, A. EA, and A. TM, "Novel pyrazolopyrimidines: Synthesis, in vitro cytotoxic activity and mechanistic investigation", European journal of medicinal chemistry, vol. 138, pp. 565-576, 2017.
Guaily, A., "Temperature Equation for Compressible Polymeric Fluids", Polymer, vol. 77: Elsevier, pp. 305–311, 2015. Abstract
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Guaily, A., and M. Epstein, "A hybrid finite element/finite difference algorithm for compressible/incompressible viscoelastic liquids", The Canadian Journal of Chemical Engineering, vol. 88, no. 6: Wiley Online Library, pp. 959–974, 2010. Abstract
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Guaily, A., and M. Epstein, "A hybrid finite element/finite difference algorithm for compressible/incompressible viscoelastic liquids", The Canadian Journal of Chemical Engineering, vol. 88, no. 6: Wiley Online Library, pp. 959–974, 2010. Abstract
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Guaily, A., "Temperature Equation for Compressible Polymeric Fluids", Polymer, vol. 77: Elsevier, pp. 305–311, 2015. Abstractguaily_temp_eqn_final.pdf

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Guaily, A., "Constitutive equation for compressible non-isothermal polymeric fluids: A microstructural approach", Journal of Molecular Liquids, vol. 308, pp. 112986, 2020.
Guaily, A. G., and M. Epstein, "Boundary conditions for hyperbolic systems of partial differentials equations", Journal of Advanced Research, vol. 4: Elsevier, pp. 321-329, 2013. Abstractguaily-epstein.pdf

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Guaily, A., and M. Epstein, "A hybrid finite element/finite difference algorithm for compressible/incompressible viscoelastic liquids", The Canadian Journal of Chemical Engineering, vol. 88, no. 6: Wiley Online Library, pp. 959–974, 2010. Abstract
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Guaily, A., E. Cheluget, K. Lee, and M. Epstein, "A new hyperbolic model and an experimental study for the flow of polymer melts in Multi-Pass Rheometer", Computers & Fluids: Elsevier, 2011. Abstract
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Guaily, A., and A. Megahed, "An adaptive finite element method for planar and axisymmetric compressible flows", Finite Elements in Analysis and Design, vol. 46, no. 8: Elsevier, pp. 613–624, 2010. Abstract
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Guaily, A., E. Cheluget, K. Lee, and M. Epstein, "A new hyperbolic model and an experimental study for the flow of polymer melts in Multi-Pass Rheometer", Computers & Fluids: Elsevier, 2011. Abstract
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Guaily, A., E. Cheluget, K. Lee, and M. Epstein, "A new hyperbolic model and an experimental study for the flow of polymer melts in Multi-Pass Rheometer", Computers & Fluids: Elsevier, 2011. Abstract
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Guaily, A., and A. Megahed, "An adaptive finite element method for planar and axisymmetric compressible flows", Finite Elements in Analysis and Design, vol. 46, no. 8: Elsevier, pp. 613–624, 2010. Abstract
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Guaily, A., and A. Megahed, "An adaptive finite element method for planar and axisymmetric compressible flows", Finite Elements in Analysis and Design, vol. 46, no. 8: Elsevier, pp. 613–624, 2010. Abstract
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Guaily, A., E. Cheluget, K. Lee, and M. Epstein, "A new hyperbolic model and an experimental study for the flow of polymer melts in Multi-Pass Rheometer", Computers & Fluids: Elsevier, 2011. Abstractauthors_pdf.pdf

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Guaily, A., and M. Epstein, "A unified hyperbolic model for viscoelastic liquids", Mechanics Research Communications, vol. 37, no. 2: Elsevier, pp. 158–163, 2010. Abstract
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Guaily, A. G., and M. Epstein, "Boundary conditions for hyperbolic systems of partial differentials equations", Journal of Advanced Research, vol. 4: Elsevier, pp. 321–329, 2013. Abstract
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Guaily, A., and M. Epstein, "A unified hyperbolic model for viscoelastic liquids", Mechanics Research Communications, vol. 37, no. 2: Elsevier, pp. 158–163, 2010. Abstract
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Guaily, A. G., and M. Epstein, "Boundary conditions for hyperbolic systems of partial differentials equations", Journal of Advanced Research, vol. 4: Elsevier, pp. 321–329, 2013. Abstract
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Guaily, A. G., and M. Epstein, "Boundary conditions for hyperbolic systems of partial differentials equations", Journal of Advanced Research, vol. 4: Elsevier, pp. 321–329, 2013. Abstract
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