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Fouda, A., H. Refai, M. and Rieth, and N. H. Mohammed., "LOW LEVEL LASER THERAPY VERSUS PULSED ELECTROMAGNETIC FIELD FOR INACTIVATION OF MYOFASCIAL TRIGGER POINTS", American Journal of Research Communication. , vol. 1, issue (3), , pp. 11, 2013.
Fouda, M. E., and A. G. Radwan, "Charge controlled memristor-less memcapacitor emulator", Electronics letters, vol. 48, no. 23: IET Digital Library, pp. 1454–1455, 2012. Abstract
Fouda, M. E., and A. G. Radwan, "On the mathematical modeling of memcapacitor bridge synapses", Microelectronics (ICM), 2014 26th International Conference on: IEEE, pp. 172–175, 2014. Abstract
Fouda, R., H. Ammar, E. Sobhy, and A. M. Amin, "Unusual cause of pericardial effusion.", BMJ case reports, vol. 2012, 2012. Abstract

A 65-year-old Egyptian lady suffering from non-alcoholic liver cirrhosis was referred to our unit for evaluation of a massive pericardial effusion. Few weeks before presentation, she suffered from progressive abdominal distention and dyspnoea. She denied fever, rigors or other cardiorespiratory symptoms. Examination revealed shrunken liver, spleenomegaly and ascites. Chest was clear to auscultation and heart sounds were distant. Chest radiograph showed cardiomegaly and clear lung fields. Abdominal ultrasound confirmed the results of abdominal examination. Transthoracic echocardiogram (TTE) revealed a massive pericardial effusion (PEF) and rheumatic mitral stenosis. Chest tomography showed PEF and clear lung fields. One litre of exudate was removed via TTE-guided needle pericardiocentesis. A pericardio-peritoneal shunt was suspected, which was confirmed via a radioisotopic study. This case is among very few cases that reported PEF in a cirrhotic ascetic patient secondary to a radio-isotopically confirmed pericardio-peritoneal shunt in the literature.

Fouda, U. M., undefined, K. A. Elsetohy, and M. A. Youssef, "Misoprostol versus uterine straightening by bladder distension for pain relief in postmenopausal patients undergoing diagnostic office hysteroscopy: a randomised controlled non-inferiority trial", European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 203, pp. 326 -330, 2016. lbhth_lrb.pdf
Fouda, M. A., R. M. Allam, F. M. Moftah, and R. A. M. El-Fetouh, "The Role of ID-NAT in Enhancing Blood Safety at the Egyptian National Cancer Institute - A 5 Year Experience", Journal of the Egyptian Society of Haematology & Research, vol. 14, issue 2, pp. 1-6, 2018.
Fouda, U. M., M. A. M. ElKassem, S. M. Hefny, and A. T. Hashem, "Role of middle cerebral artery, umbilical artery resistance indices and middle cerebral artery to umbilical artery resistance index ratio in predicting unfavorable perinatal outcomes of normotensive and hypertensive diabetic pregnancies ", Life Science Journal, vol. 10, issue 3, pp. 2371-2377, 2013. Abstract

Objective: To evaluate the role of middle cerebral artery (MCA), umbilical artery (UA)resistance indices (RI) and middle cerebral artery / umbilical artery resistance index ratio(MCA/UA RI) in predicting unfavorable perinatal outcomes in pregnancies complicated with diabetes mellitus. Methods: This prospective study included 96 women divided into 4 groups. Group 1 included 23 pregnant patients with preexisting diabetes, group 2 included 22 patients with gestational diabetes, group 3 included 24 diabetic pregnancies associated with hypertension and group 4 was a control group which included 27 patients with uncomplicated pregnancies. The umbilical artery and middle cerebral artery resistance indices were measured weekly starting from the 34th till the 38th week of pregnancy. Results: Abnormal UA RI (≥ 95th centile) had 78.57% sensitivity in detecting adverse perinatal outcomes in group 3 compared with 16.67 % and 0% sensitivity in group 1 and group 2 respectively. Abnormal MCA RI (≤ 5th centile) had 50% sensitivity in detecting adverse perinatal outcomes in group 3 compared with 0% sensitivity in groups 1 and 2. Abnormal MCA/UA RI (< 1) had 71.43 % sensitivity in detecting adverse perinatal outcomes in group 3 compared with 0 % sensitivity in groups 1 and 2. Conclusion: The abnormal UA RI, MCA RI and MCA/UA RI may be useful parameters in predicting adverse perinatal outcomes in diabetic pregnancies associated with hypertension. On the other hand, there were weak correlations between abnormal UA RI, MCA RI, MCA/UA RI and adverse perinatal outcomes of diabetic pregnancies not associated with hypertension. Therefore the results of the UA RI, MCA RI and MCA/UA RI should be interpreted with caution in the management of diabetic pregnancies, especially those not associated with hypertension, as adverse perinatal outcomes frequently occur in patients with normal Doppler indices.

Fouda, U. M., and A. M. Sayed, "Effect of Ultrasound-Guided Aspiration of Hydrosalpingeal Fluid During Oocyte Retrieval on the Outcomes of in Vitro Fertilisation-Embryo Transfer: A Randomised Controlled Trail", Gynecological Endocrinology, 2011. Abstract

Objective: To determine whether the ultrasound-guided aspiration of hydrosalpingeal fluid at the time of oocyte retrievalvcan improve the outcomes of in vitro fertilisation-embryo transfer (IVF-ET).

Fouda, R., Y. Abdelhamid, D. Alsayed, S. Salah, D. Belal, M. Salem, and H. Ahmed, "Pulmonary Hypertension in Chronic Kidney Disease Patients on Conservative Treatment and on Dialysis. Relation to Nitric Oxide", African Journal of Nephrology, vol. 17, pp. 26-30, 2013. Abstract


Fouda, M. E., and A. G. Radwan, "Fractional-order Memristor Response Under DC and Periodic Signals", Circuits, Systems, and Signal Processing: Springer US, pp. 1–10, 2014. Abstract
Fouda, M. E., A. AboBakr, A. S. Elwakil, A. G. Radwan, and A. M. Eltawil, "Simple MOS Transistor-Based Realization of Fractional-Order Capacitors", 2019 IEEE International Symposium on Circuits and Systems (ISCAS): IEEE, pp. 1-4, 2019. Abstract
Fouda, M. E., and A. G. Radwan, "Simple floating voltage-controlled memductor emulator for analog applications", Radioengineering, vol. 23, no. 3: Directory of Open Access Journals, pp. 944–948, 2014. Abstract
Fouda, M. E., A. M. Eltawil, and F. Kurdahi, "On resistive memories: One step row readout technique and sensing circuitry", arXiv preprint arXiv:1903.01512, 2019. Abstract
Fouda, M. E., A. S. Elwakil, A. G. Radwan, and A. Allagui, "Power and energy analysis of fractional-order electrical energy storage devices", Energy, vol. 111: Pergamon, pp. 785–792, 2016. Abstract
Fouda, M. E., A. S. Elwakil, A. G. Radwan, and B. J. Maundy, "Fractional-order two-port networks", Mathematical Problems in Engineering, vol. 2016: Hindawi, 2016. Abstract
Fouda, A. Y., A. S. Newsome, S. Spellicy, J. L. Waller, W. Zhi, D. C. Hess, A. Ergul, D. J. Edwards, S. C. Fagan, and J. A. Switzer, "Minocycline in Acute Cerebral Hemorrhage: An Early Phase Randomized Trial.", Stroke, vol. 48, issue 10, pp. 2885-2887, 2017 10. Abstract

BACKGROUND AND PURPOSE: Minocycline is under investigation as a neurovascular protective agent for stroke. This study evaluated the pharmacokinetic, anti-inflammatory, and safety profile of minocycline after intracerebral hemorrhage.

METHODS: This study was a single-site, randomized controlled trial of minocycline conducted from 2013 to 2016. Adults ≥18 years with primary intracerebral hemorrhage who could have study drug administered within 24 hours of onset were included. Patients received 400 mg of intravenous minocycline, followed by 400 mg minocycline oral daily for 4 days. Serum concentrations of minocycline after the last oral dose and biomarkers were sampled to determine the peak concentration, half-life, and anti-inflammatory profile.

RESULTS: A total of 16 consecutive eligible patients were enrolled, with 8 randomized to minocycline. Although the literature supports a time to peak concentration (T) of 1 hour for oral minocycline, the T was estimated to be at least 6 hours in this cohort. The elimination half-life (available on 7 patients) was 17.5 hours (SD±3.5). No differences were observed in inflammatory biomarkers, hematoma volume, or perihematomal edema. Concentrations remained at neuroprotective levels (>3 mg/L) throughout the dosing interval in 5 of 7 patients.

CONCLUSIONS: In intracerebral hemorrhage, a 400 mg dose of minocycline was safe and achieved neuroprotective serum concentrations. However, oral administration led to delayed absorption in these critically ill patients and should not be used when rapid, high concentrations are desired. Given the safety and pharmacokinetic profile of minocycline in intracerebral hemorrhage and promising data in the treatment of ischemic stroke, intravenous minocycline is an excellent candidate for a prehospital treatment trial.

CLINICAL TRIAL REGISTRATION: URL: Unique identifier: NCT01805895.

Fouda, M. E., A. Allagui, A. S. Elwakil, S. Das, C. Psychalinos, and A. G. Radwan, "Nonlinear charge-voltage relationship in constant phase element", AEU-International Journal of Electronics and Communications, vol. 117: Urban & Fischer, pp. 153104, 2020. Abstract
Fouda, U. M., A. M. Sayed, H. S. Elshaer, B. E. M. Hammad, M. M. Shaban, K. A. Elsetohy, and M. A. Youssef, "GnRH antagonist rescue protocol combined with cabergoline versus cabergoline alone in the prevention of ovarian hyperstimulation syndrome: a randomized controlled trial.", Journal of ovarian research, vol. 9, issue 1, pp. 29, 2016 May 17. Abstract

BACKGROUND: The aim of this study was to compare the efficacy of antagonist rescue protocol (replacing GnRH agonist with GnRH antagonist and reducing the dose of gonadotropins) combined with cabergoline versus cabergoline alone in the prevention of ovarian hyperstimulation syndrome (OHSS) in patients pretreated with GnRH agonist long protocol who were at high risk for OHSS.

METHODS: Two hundred and thirty six patients were randomized in a 1:1 ratio to the cabergoline group or the antagonist rescue combined with cabergoline group. Both groups received oral cabergoline (0.5 mg/day) for eight days beginning on the day of HCG administration. In the antagonist rescue combined with cabergoline group, when the leading follicle reached 16 mm, GnRH agonist (triptorelin) was replaced with GnRH antagonist (cetrorelix acetate) and the dose of HP-uFSH was reduced to 75 IU/day. HCG (5,000 IU/I.M) was administered when the serum estradiol level dropped below 3500 pg/ml. The study was open label and the outcome assessors (laboratory staff and the doctor who performed oocyte retrieval) were blind to treatment allocation.

RESULTS: The incidence of moderate/severe OHSS was significantly lower in the antagonist rescue combined with cabergoline group [5.08 % Vs 13.56 %, P value =0.025, OR = 0.342, 95 % CI, 0.129-0.906]. Four cycles were cancelled in the cabergoline group. There were no significant differences between the groups with respect to the number of retrieved oocytes, metaphase II oocytes, high quality embryos and fertilization rate. Moreover, the implantation and pregnancy rates were comparable between both groups.

CONCLUSION: GnRH antagonist rescue protocol combined with cabergoline is more effective than cabergoline alone in the prevention of OHSS.

TRIAL REGISTRATION: Clinical ( NCT02461875 ).

Fouda, M. E., M. A. Khatib, and A. G. Radwan, "On the mathematical modeling of series and parallel memcapacitors", Microelectronics (ICM), 2013 25th International Conference on: IEEE, pp. 1–4, 2013. Abstract
Fouda, K. Z., and M. E. H. Laithy, "1. Effect of low energy versus medium energy radial shock wave therapy in the treatment of chronic planter fasciitis. ", Int J Physiother., vol. 3, issue 1, pp. 5-10, 2016.
Fouda, A. Y., Z. Xu, E. shosha, T. Lemtalsi, J. Chen, H. A. Toque, R. Tritz, X. Cui, B. K. Stansfield, Y. Huo, et al., "Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses.", Cell death & disease, vol. 9, issue 10, pp. 1001, 2018. Abstract

The lack of effective therapies to limit neurovascular injury in ischemic retinopathy is a major clinical problem. This study aimed to examine the role of ureohydrolase enzyme, arginase 1 (A1), in retinal ischemia-reperfusion (IR) injury. A1 competes with nitric oxide synthase (NOS) for their common substrate L-arginine. A1-mediated L-arginine depletion reduces nitric oxide (NO) formation by NOS leading to vascular dysfunction when endothelial NOS is involved but prevents inflammatory injury when inducible NOS is involved. Studies were performed using wild-type (WT) mice, global A1 knockout (KO), endothelial-specific A1 KO, and myeloid-specific A1 KO mice subjected to retinal IR injury. Global as well as myeloid-specific A1 KO mice showed worsened IR-induced neuronal loss and retinal thinning. Deletion of A1 in endothelial cells had no effect, while treatment with PEGylated (PEG) A1 improved neuronal survival in WT mice. In addition, A1 KO mice showed worsened vascular injury manifested by increased acellular capillaries. Western blotting analysis of retinal tissue showed increased inflammatory and necroptotic markers with A1 deletion. In vitro experiments showed that macrophages lacking A1 exhibit increased inflammatory response upon LPS stimulation. PEG-A1 treatment dampened this inflammatory response and decreased the LPS-induced metabolic reprogramming. Moreover, intravitreal injection of A1 KO macrophages or systemic macrophage depletion with clodronate liposomes increased neuronal loss after IR injury. These results demonstrate that A1 reduces IR injury-induced retinal neurovascular degeneration via dampening macrophage inflammatory responses. Increasing A1 offers a novel strategy for limiting neurovascular injury and promoting macrophage-mediated repair.

Fouda, K. Z., "Efficacy of Radial Shock Wave Therapy on Spasticity in Stroke Patients", International Journal of Health and Rehabilitation Sciences, vol. 4, issue 1, pp. 19-26, 2015. publish-1-rswt-2015.pdf