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Fadel, F., H. M. Bazraa, S. M. Abdelrahman, M. G. Shoman, M. k Sayed, D. M. Salah, A. m Wahby, and H. F. Elgebaly, "Visfatin versus Flow-Mediated Dilatation as a Marker of Endothelial Dysfunction in Pediatric Renal Transplant Recipients", Open Access Macedonian Journal of medical Science, vol. 5, issue 1857-9655, pp. 222-227, 2017.
Fadel, M., K. Kassab, and D. A. Fadeel, "Zinc phthalocyanine-loaded PLGA biodegradable nanoparticles for photodynamic therapy in tumor-bearing mice", Lasers in medical science, vol. 25, no. 2: Springer-Verlag, pp. 283–292, 2010. Abstract
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Fadel, M. A., and A. A. Tawfik, "New topical photodynamic therapy for treatment of hidradenitis suppurativa using methylene blue niosomal gel: a single-blind, randomized, comparative study", Clinical and experimental dermatology, vol. 40, no. 2, pp. 116–122, 2015. Abstract
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Fadel, M., K. Kassab, N. Samy, and S. Thabet, European Journal of Biomedical AND Pharmaceutical sciences, , 2015. Abstract
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Fadel, F. I., S. A. E. Sherbiny, A. M. Badr, H. A. F. E. Gebaly, and D. M. Osman, CHARACTERISTICS OF SEPTIC PEDIATRIC PATIENTS WITH ACUTE KIDNEY INJURY IN PICU, , 2018.
Fadel, M., N. Samy, M. Nasr, and A. A. Alyoussef, "Topical colloidal indocyanine green-mediated photodynamic therapy for treatment of basal cell carcinoma", Pharmaceutical Development and Technology, vol. 22, no. 4, pp. 545 – 550, 2017. AbstractWebsite
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Fadel, N., H. el dahab, and S. hassan osman, the efficacy of fentanyl in management of emrgence hypertension in neurosurgery patients , , cairo, cairo university, 2011.
Fadel, M., D. A. Fadeel, A. Tawfik, A. I. El-Kholy, and Y. O. Mosaad, "Rose Bengal-gold-polypyrrole nanoparticles as a photothermal/photodynamic dual treatment of recalcitrant plantar warts: Animal and clinical study", Journal of Drug Delivery Science and Technology, vol. 69, 2022. AbstractWebsite
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Fadel, M., and K. Kassab, "Evaluation of the photostability and photodynamic efficacy of Rose Bengal loaded in multivesicular liposomes", Tropical Journal of Pharmaceutical Research, vol. 10, no. 3, 2011. Abstract
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Fadel, F. I., D. M. Salah, and H. M. Bazaraa, "Localized Renal Graft Aspergillosis in a Child after Kidney Transplantation: Case Report and Review of Literature", Virology & Mycology, vol. 5, issue 3, pp. 160-164, 2016.
Fadel, S., H. Hafiz, R. Khedr, H. Taha, N. Elkinaai, A. Younes, M. Elwakeel, N. Mohamed, and M. Tantawy, "CHARACTERISTICS AND OUTCOME OF HEPATOBLASTOMA PATIENTS: EXPERIENCE OF CHILDREN CANCER HOSPITAL EGYPT", PEDIATRIC BLOOD & CANCER, vol. 63: WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, pp. S172-S173, 2016. Abstract
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Fadel, M. A., and A. A. Tawfik, "New topical photodynamic therapy for treatment of hidradenitis suppurativa using methylene blue niosomal gel: a single-blind, randomized, comparative study", Clinical and experimental dermatology, vol. 40, no. 2, pp. 116–122, 2015. Abstract
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Fadel, F. I., S. Sabry, M. A. A. Mawla, R. E. E. Galal, D. M. Salah, R. Helmy, Y. Ramadan, W. Elzayat, M. Abdelfattah, and E. A. Abd Alazem, "Covid-19 in Egyptian hemodialysis and kidney transplant children: retrospective analysis of single center experience.", Italian journal of pediatrics, vol. 48, issue 1, pp. 149, 2022. Abstract

BACKGROUND: Chronic kidney disease stage 5 (CKD 5) populations have peculiar risk for severe Covid-19 infection. Moreover; pediatric data are sparse and lacking. The aim of this study is to report our experience in CKD 5 children treated by hemodialysis (CKD 5D) and CKD 5 children after kidney transplantation (KTR) during one year of Covid-19 pandemic.

METHODS: Retrospective analysis of 57 CKD 5 children with Covid-19 like symptoms during 1 year pandemic was performed. A cohort of 19 confirmed patients (13 CKD 5D and 6 KTR) was analyzed in details as regard clinical, laboratory, radiological criteria, management and their short term outcome.

RESULTS: CONCLUSION: Pediatric patients on regular HD (CKD 5D) are at higher risk and worse outcome of Covid-19 infection than KT recipients (KTR). Pre-existing HTN and shorter duration after KT are potential risk factors. Reversible AGD after KT and CVC related infections in HD patients are additional presenting features of Covid-19 infection.

Fadel, M., K. Kassab, T. Youssef, and A. I. El-Kholy, "One-step synthesis of phyto-polymer coated gold nanospheres as a delivery system to enhance resveratrol cytotoxicity", Drug Development and Industrial Pharmacy, vol. 45, no. 6, pp. 937 – 945, 2019. AbstractWebsite
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Fadel, M. M., K. E. G. -Iraqi, R. A. Ghandour, and M. A. Foad, "Feed Restriction Regimens Effects On Growth and Physiological Performance of Fattening rabbits", Journal of Egyptian veterinary medical Association, vol. 79, issue 3, pp. 791-802, 2019. rabbit_papper_.pdf
Fadel, M., M. Salah, N. Samy, and S. Mona, "Liposomal methylene blue hydrogel for selective photodynamic therapy of acne vulgaris.", Journal of drugs in dermatology: JDD, vol. 8, no. 11, pp. 983–990, 2009. Abstract
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Fadel, M., K. Kassab, Doaa A. Abd El Fadeel, and M. A. Farag, "Topical photodynamic therapy of tumor bearing mice with meso-tetrakis (Nmethyl-4-pyridyl) porphyrin loaded in ethosomes", Photodiagnosis and Photodynamic Therapy, vol. 30 , issue 10, pp. 1789 , 2020.
Fadel, M., K. Kassab, and T. Youssef, "Photodynamic efficacy of hypericin targeted by two delivery techniques to hepatocellular carcinoma cells", Lasers in medical science, vol. 25, no. 5: Springer, pp. 675–683, 2010. Abstract
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Fadel, M., and K. Kassab, "Evaluation of the photostability and photodynamic efficacy of Rose Bengal loaded in multivesicular liposomes", Tropical Journal of Pharmaceutical Research, vol. 10, no. 3, 2011. Abstract
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Fadel, M., K. Kassab, D. A. E. A. Fadeel, and M. A. Farag, "Topical photodynamic therapy of tumor bearing mice with meso-tetrakis (N-methyl-4-pyridyl) porphyrin loaded in ethosomes", Photodiagnosis and Photodynamic Therapy, vol. 30: Elsevier, pp. 101789, 2020. Abstract
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Fadel, M., G. Abdelbary, S. F. Elmenshawe, and E. Eissa, "Toluidine blue loaded transferosomes for topical photodynamic therapy: Formulation and characterization", International Journal of Research in Pharmaceutical Sciences, vol. 2, no. 4, pp. 537 – 544, 2011. AbstractWebsite
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Fadel, F. I., M. F. Elshamaa, A. Salah, E. A. Elghoroury, S. A. El-Rahman, M. Hamed Ibrahim, and S. Kamel, "FcγRIIa defunctioning polymorphism in paediatric patients with renal allograft.", Central-European journal of immunology, vol. 42, issue 4, pp. 363-369, 2017. Abstract

Introduction: Fc gamma receptor (FcγR) IIa is considered the most widely distributed of the three classes of Fc receptors, and it expresses an allelic polymorphism. This type of polymorphism may modify the immune response and may be an important factor for some diseases. The aim of the study reported herein was to evaluate the association between the FcγRIIa polymorphism and susceptibility to both end-stage renal disease (ESRD) and acute kidney graft rejection (AR) in children who have undergone renal transplantation.

Material and methods: The study evaluated 70 children who had undergone transplantation and 60 healthy subjects. AR was observed in 25 children.

Results: FcγRIIa genotypes and alleles were significantly different between transplantation patients and the control group. The assessment for FcγR of the groups in which AR was present showed that there was only a risk of having an acute rejection in homozygous genotype RR.

Conclusions: FcγRIIa RR genotype and allele frequency was increased in paediatric renal transplant recipients. The present findings showed that FcγRIIa genotype may be related to ESRD disease susceptibility, and FcγRIIa polymorphisms seemed to affect AR.

Fadel, F. I., H. M. Bazaraa, H. Badawy, H. A. Morsi, G. Saadi, M. A. Abdel Mawla, amr mohamed salem, E. A. Abd Alazem, R. Helmy, M. G. Fathallah, et al., "Pediatric kidney transplantation in Egypt: Results of 10-year single-center experience.", Pediatric transplantation, vol. 24, issue 6, pp. e13724, 2020. AbstractPediatric kidney transplantation in Egypt: Results of 10-year single-center experience.pdf

Pediatric kidney transplantation is a multidisciplinary therapy that needs special consideration and experience. In this study, we aimed to present CUCH experience; over a 10-year period, as a specialized center of kidney transplantation in children. We studied 148 transplantations performed at a single center from 2009 to 2018. Pretransplant and follow-up data were collected and graft/patient survival rates were evaluated. A total of 48 patients developed at least one rejection episode during 688 patient-years of follow-up. Infections, recurrence of original disease, and malignancy were the most important encountered medical complications (20%, 2%, and 1.4%, respectively). One-year patient survival was 94.1%, while graft and patient survival was 91.9%. Graft/patient survival at 5, 7, and 9 years was 90%, 77%, and 58%, respectively. Infections were the main cause (69%) of mortality. Death with a functioning graft and CR were the main causes of graft loss (48% and 33%, respectively). Pediatric kidney transplantation in Egypt is still a challenging yet successful experience. Rejections and infections are the most frequent complications. Short-term outcomes surpass long-term ones and graft survival rates are similar to the international standard.

Fadel, S. A., M. M. Gaafar, O. E. Teneer, and I. A. Attia, ROLE OF TOPOTECAN IN REFRACTORY NEUROBLASTOMA, , Cairo, Cairo, 2002.
Fadel, F. I., H. M. Bazaraa, M. A. Abdel Mawla, and D. M. Salah, "Pediatric focal segmental glomerulosclerosis: favorable transplantation outcome with plasma exchange.", Italian journal of pediatrics, vol. 47, issue 1, pp. 236, 2021. Abstract

BACKGROUND: Although kidney transplantation (KTX) is the treatment of choice for pediatric end stage kidney disease (ESKD); concerns for recurrence in cases of focal segmental glomerulosclerosis (FSGS) are still present. This study aimed to investigate the outcome of KTX in children with ESKD secondary to FSGS, with implementation of preemptive perioperative plasma exchange (PE) for non-genetically proven patients.

METHODS: Forty FSGS pediatric kidney transplant recipients were studied. Of them: 12 patients (30%) had genetically proven NPHS2 mutations/familial and 28 (70%) were sporadic FSGS patients. All sporadic patients electively received 6 perioperative PE sessions. Patients with recurrence of proteinuria (n = 13; including 3 patients with genetic/familial and 10 patients with sporadic FSGS) were managed with PE and Rituximab (RTX). Kaplan-Meier curves were used to analyze graft and recurrence free survival data.

RESULTS: The mean follow-up duration after KTX was 3.8 ± 2.86 years. Recurrence of proteinuria was encountered early postoperative in 11 patients (27.5%) and late (1.6 and 2.9 years after KTX) in 2 patients (5%). All patients with early recurrence achieved complete remission, while patients with late recurrence developed graft failure. Current serum creatinine and proteinuria levels were not different in patients received PE (n = 31) and patients did not PE (n = 9) (p = 0.308 and 0.287 respectively). Current serum creatinine and proteinuria levels in sporadic patients (n = 28) after prophylactic perioperative PE were not different from those of genetic/ familial patients (n = 12) (p = 0.303 and 0.144 respectively). Proteinuria was less in patients underwent native nephrectomy than others immediately postoperative and at assessment (p = 0.002 & 0.0031 respectively). One-year graft and patient survival was 93.8% with a mean 1-year serum creatinine of 0.67 ± 0.25 mg/dl. Three graft losses (7.5%) were due to chronic rejection 3.3, 3.75 and 4.17 years after KTX and 2 patients' mortality (5%) occurred early postoperative (first 2 weeks).

CONCLUSION: FSGS transplanted children have favorable outcomes with perioperative PE for non-genetically proven cases. Early recurrence after KTX can be successfully managed with PE and RTX.