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Fouda, A. S., M. H. AboulFotouh, K. H. Attia, and A. M. Aboulezezz, "Carriere Motion Appliance with Miniscrew Anchorage for Treatment of Class II, Division 1 Malocclusion", Journal of clinical orthodontics: JCO, vol. 54, issue 10, pp. 633-641, 2020. Abstract
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Fouda, M. E., and A. G. Radwan, "Power dissipation of memristor-based relaxation oscillators", Radioengineering, vol. 24, no. 4: Directory of Open Access Journals, pp. 968–973, 2015. Abstract
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Fouda, M. E., A. M. Eltawil, and F. Kurdahi, "Modeling and analysis of passive switching crossbar arrays", IEEE Transactions on Circuits and Systems I: Regular Papers, vol. 65, issue 1: IEEE, pp. 270-282, 2018. Abstract
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Fouda, M. E., A. G. Radwan, and A. Elwakil, "Memristor and Inverse Memristor: Modeling, Implementation and Experiments", Advances in Memristors, Memristive Devices and Systems: Springer International Publishing, pp. 371–392, 2017. Abstract
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Fouda, U. M., K. A. Elsetohy, H. S. Elshaer, B. E. M. Hammad, M. M. Shaban, M. A. Youssef, A. T. Hashem, and A. H. Attia, "Misoprostol Prior to Diagnostic Office Hysteroscopy in the Subgroup of Patients with No Risk Factors for Cervical Stenosis: A Randomized Double Blind Placebo-Controlled Trial.", Gynecologic and obstetric investigation, vol. 83, issue 5, pp. 455-460, 2018. Abstract

AIMS: To assess the effectiveness of vaginal misoprostol in minimizing the pain perceived by patients with no risk factors for cervical stenosis (i.e., parous women of reproductive age who have no history of cesarean section or cervical surgery) during diagnostic office hysteroscopy.

METHODS: A total of 100 patients with no risk factors for cervical stenosis were randomized to the misoprostol group (n = 50) or the placebo group (n = 50). In the misoprostol group, 2 misoprostol tablets (400 µg) were administered vaginally 12 h before office hysteroscopy. In the placebo group, 2 placebo tablets were administered. The patients rated the intensity of pain perceived during the procedure and at 30 min after the procedure with the use of a 100 mm visual analog scale (VAS). The hysteroscopists also scored the difficulty of hysteroscope insertion into the uterine cavity with the use of a 100 mm VAS.

RESULTS: There were no significant differences between both groups in the VAS pain scores during or at 30 min after the procedure (28.3 ± 13.58 vs. 30.42 ± 15.13 and 11.1 ± 10.23 vs. 13.32 ± 11.12, respectively). The difficulty of hysteroscope insertion into the uterine cavity was comparable between both groups.

CONCLUSION: Misoprostol administration prior to diagnostic office hysteroscopy appears to have no beneficial role in the subgroup of patients with no risk factors for cervical stenosis.

Fouda, N. H., R. T. A. E. Rehim, D. A. Hegazy, and B. A. Habib, "Sustained ocular delivery of Dorzolamide- HCl via proniosomal gel formulation: in-vitro characterization, statistical optimization, and invivo pharmacodynamic evaluation in rabbits", DRUG DELIVERY, vol. 25, issue 1, pp. 1340–1349, 2018.
Fouda, M. E., M. A. Khatib, A. G. Mosad, and A. G. Radwan, "Generalized Analysis of Symmetric and Asymmetric Memristive Two-Gate Relaxation Oscillators", IEEE Tcas I, no. 99: IEEE, pp. 1–8, 2013. Abstract
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Fouda, M. E., and A. G. Radwan, "Meminductor response under periodic current excitations", Circuits, Systems, and Signal Processing, vol. 33, no. 5: Springer US, pp. 1573–1583, 2014. Abstract
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Fouda, K. Z., and M. E. H. Laithy, "1. Effect of low energy versus medium energy radial shock wave therapy in the treatment of chronic planter fasciitis. ", Int J Physiother., vol. 3, issue 1, pp. 5-10, 2016.
Fouda, K. Z., "Effect of Low Energy versus Medium Energy Radial Shock Wave Therapy in The Treatment of Chronic Planter Fasciitis", International Journal of Physiotherapy , vol. 3, issue 1, pp. 5-10, 2016. final_article_2016.pdf
Fouda, M. E., A. S. Elwakil, and A. G. Radwan, "Pinched hysteresis with inverse-memristor frequency characteristics in some nonlinear circuit elements", Microelectronics journal, vol. 46, no. 9: Elsevier, pp. 834–838, 2015. Abstract
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Fouda, M. E., and A. G. Radwan, "ON THE FRACTIONAL-ORDER MEMRISTOR MODEL", Journal of Fractional Calculus and Applications, vol. 4, no. 1, pp. 1–7, 2013. Abstract
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Fouda, R., H. Ammar, E. Sobhy, and A. M. Amin, "Unusual cause of pericardial effusion.", BMJ case reports, vol. 2012, 2012 Sep 04. Abstract

A 65-year-old Egyptian lady suffering from non-alcoholic liver cirrhosis was referred to our unit for evaluation of a massive pericardial effusion. Few weeks before presentation, she suffered from progressive abdominal distention and dyspnoea. She denied fever, rigors or other cardiorespiratory symptoms. Examination revealed shrunken liver, spleenomegaly and ascites. Chest was clear to auscultation and heart sounds were distant. Chest radiograph showed cardiomegaly and clear lung fields. Abdominal ultrasound confirmed the results of abdominal examination. Transthoracic echocardiogram (TTE) revealed a massive pericardial effusion (PEF) and rheumatic mitral stenosis. Chest tomography showed PEF and clear lung fields. One litre of exudate was removed via TTE-guided needle pericardiocentesis. A pericardio-peritoneal shunt was suspected, which was confirmed via a radioisotopic study. This case is among very few cases that reported PEF in a cirrhotic ascetic patient secondary to a radio-isotopically confirmed pericardio-peritoneal shunt in the literature.

Fouda, U. M., and A. M. Sayed, "Effect of ultrasound-guided aspiration of hydrosalpingeal fluid during oocyte retrieval on the outcomes of in vitro fertilisation-embryo transfer: a randomised controlled trial (NCT01040351).", Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, vol. 27, issue 8, pp. 562-7, 2011 Aug. Abstract

OBJECTIVE: To determine whether the ultrasound-guided aspiration of hydrosalpingeal fluid at the time of oocyte retrieval can improve the outcomes of in vitro fertilisation-embryo transfer (IVF-ET).

PATIENTS: One hundred and ten women with ultrasound-visible hydrosalpinges were randomised to two groups based on computer generated randomisation list. Fifty-four women underwent ultrasound-guided aspiration of hydrosalpingeal fluid prior to IVF-ET and 53 women underwent IVF-ET without any prior intervention.

RESULTS: Patients who underwent aspiration of hydrosalpinges demonstrated a significantly increased implantation, clinical pregnancy rates. Among the patients in the aspiration group, the implantation rate and pregnancy rates were higher in the subgroup of patients with no reaccumulation of hydrosalpingeal fluid within the first 2 weeks after aspiration compared to patients with reaccumulation of hydrosalpingeal fluid within the first 2 weeks after aspiration, but this difference failed to reach statistical significance. Furthermore, no pregnancies occurred in the four patients with uterine fluid collection detected during IVF-ET cycles.

CONCLUSION: The aspiration of hydrosalpingeal fluid at the time of oocyte retrieval is simple, safe and effective procedure for treatment of patients with ultrasound-visible hydrosalpinges particularly those without rapid reaccumulation of hydrosalpingeal fluid after aspiration or uterine fluid collection during the IVF-ET cycles.

Fouda, U. M., A. M. Sayed, A. - M. A. Abdou, D. R. I. b, I. F. M. c, and M. Z. M. d, Enoxaparin versus unfractionated heparin in the management of recurrent abortion secondary to antiphospholipid syndrome, , vol. 112, issue 3, 2011. cu_pdf.pdf
Fouda, U. M., N. M. Salah Eldin, K. A. Elsetohy, H. A. Tolba, M. M. Shaban, and S. M. Sobh, "Diclofenac plus lidocaine gel for pain relief during intrauterine device insertion. A randomized, double-blinded, placebo-controlled study.", Contraception, vol. 93, issue 6, pp. 513-8, 2016 Jun. Abstract

OBJECTIVE: To determine the effectiveness of diclofenac potassium combined with 2% lidocaine gel in reducing the pain of intrauterine device (IUD) insertion.

STUDY DESIGN: We randomized 90 parous women requesting copper T380A IUD insertion in a 1:1 ratio to active or placebo treatment. Active treatment included administration of two 50-mg diclofenac potassium tablets 1h before IUD insertion, application of 3mL of 2% lidocaine gel on the anterior cervical lip 3min before IUD insertion and placement of a cotton swab soaked in 2% lidocaine gel in the cervical canal 3min before IUD insertion. Women in the placebo group received placebo tablets and gel. Participants assessed pain intensity using a 10-cm visual analog scale (VAS). We considered a 2-cm difference in VAS pain score between both groups during IUD insertion to be a clinically significant difference.

RESULTS: Subjects receiving active treatment, as compared to placebo, experienced less pain during tenaculum placement (1.66±0.85 vs. 2.33±1.19, p=.003) and IUD insertion (3.14±0.92 vs. 3.94±1.3, p=.001). Women who delivered only by cesarean section had higher pain scores with IUD insertion compared with women with previous vaginal deliveries (4.41±1.24 vs. 3.29±1.05, p=.001).

CONCLUSION: Diclofenac potassium combined with 2% lidocaine gel slightly reduced pain scores during tenaculum application and copper IUD insertion in parous women; however, the reduction in pain scores lacked clinical significance.

IMPLICATIONS: Although we found a statistically significant lowering of pain scores with pretreatment with diclofenac potassium and lidocaine gel in parous women having copper IUD placement, the reduction is not clinically relevant. These findings may be more relevant for nulliparous women who experience more pain than parous women with IUD insertion and support studies of diclofenac potassium and lidocaine gel in this population.

Fouda, T., M. Abul-Dahab, and H. Fathy, "Predictors of morbidity and mortality in redo mitral valve replacement for prosthetic mechanical mitral valve dysfunction /", Journal Of the Egyptian Society Of Cardiothoracic Surgery, 2014.
Fouda, U. M., A. M. Sayed, D. I. Ramadan, and I. M. Fouda, "Efficacy and safety of two doses of low molecular weight heparin (enoxaparin) in pregnant women with a history of recurrent abortion secondary to antiphospholipid syndrome.", Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, vol. 30, issue 8, pp. 842-6, 2010. Abstract

The aim of this randomised controlled trial was to compare efficacy and safety of two doses of low molecular weight heparin (enoxaparin) in pregnant women with a history of recurrent abortion secondary to antiphospholipid syndrome. A total of 60 women with a minimum of three consecutive abortions before 10 weeks' gestation and positive lupus anticoagulant and/or anticardiolipin antibodies on at least two occasions at least 12 weeks apart were randomised into two groups based on computer generated randomisation list concealed in opaque envelopes. Pregnant women were treated with enoxaparin 40 mg plus low dose aspirin (LDA) (n = 30) or enoxaparin 20 mg plus LDA (n = 30). The live birth rate was 76.67% in enoxaparin 40 mg group and 70% in enoxaparin 20 mg group (p value = 0.559). There were no significant differences between both groups with respect to neonatal outcome, obstetric and maternal complications during pregnancy or puerperium. No cases of severe bleeding, thrombocytopenia or spontaneous fractures were reported in both groups.

Fouda, M. E., A. G. Radwan, and K. N. Salama, "Effect of boundary on controlled memristor-based oscillator", Engineering and Technology (ICET), 2012 International Conference on: IEEE, pp. 1–5, 2012. Abstract
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Fouda, M. E., and A. G. Radwan, "Memristor-less current-and voltage-controlled meminductor emulators", Electronics, Circuits and Systems (ICECS), 2014 21st IEEE International Conference on: IEEE, pp. 279–282, 2014. Abstract
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Fouda, M. E., and A. G. Radwan, "Boundary Dynamics of Memcapacitor in Voltage-Excited Circuits and Relaxation Oscillators", Circuits, Systems, and Signal Processing, vol. 34, no. 9: Springer US, pp. 2765–2783, 2015. Abstract
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Fouda, M. E., A. G. Radwan, and A. Elwakil, "Memristor and Inverse Memristor: Modeling, Implementation and Experiments", Advances in Memristors, Memristive Devices and Systems: Springer, Cham, pp. 371–392, 2017. Abstract
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Fouda, A. Y., W. Eldahshan, Z. Xu, T. Lemtalsi, E. shosha, S. A. Zaidi, A. A. Abdelrahman, P. N. - M. Cheng, P. S. Narayanan, W. R. Caldwell, et al., "Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury.", Experimental neurology, vol. 348, pp. 113923, 2021. Abstract

Arginase 1 (A1) is the enzyme that hydrolyzes the amino acid, L-arginine, to ornithine and urea. We have previously shown that A1 deletion worsens retinal ischemic injury, suggesting a protective role of A1. In this translational study, we aimed to study the utility of systemic pegylated A1 (PEG-A1, recombinant human arginase linked to polyethylene glycol) treatment in mouse models of acute retinal and brain injury. Cohorts of WT mice were subjected to retinal ischemia-reperfusion (IR) injury, traumatic optic neuropathy (TON) or brain cerebral ischemia via middle cerebral artery occlusion (MCAO) and treated with intraperitoneal injections of PEG-A1 or vehicle (PEG only). Drug penetration into retina and brain tissues was measured by western blotting and immunolabeling for PEG. Neuroprotection was measured in a blinded fashion by quantitation of NeuN (neuronal marker) immunolabeling of retina flat-mounts and brain infarct area using triphenyl tetrazolium chloride (TTC) staining. Furthermore, ex vivo retina explants and in vitro retina neuron cultures were subjected to oxygen-glucose deprivation (OGD) followed by reoxygenation (R) and treated with PEG-A1. PEG-A1 given systemically did not cross the intact blood-retina/brain barriers in sham controls but reached the retina and brain after injury. PEG-A1 provided neuroprotection after retinal IR injury, TON and cerebral ischemia. PEG-A1 treatment was also neuroprotective in retina explants subjected to OGD/R but did not improve survival in retinal neuronal cultures exposed to OGD/R. In summary, systemic PEG-A1 administration is neuroprotective and provides an excellent route to deliver the drug to the retina and the brain after acute injury.

Fouda, U. M., K. A. Elsetohy, and H. S. Elshaer, "Barbed Versus Conventional Suture: A Randomized Trial for Suturing the Endometrioma Bed After Laparoscopic Excision of Ovarian Endometrioma.", J Minim Invasive Gynecol. 2016 , vol. 23, issue 6, pp. 962-8, 2016.
Fouda, R., H. Ammar, E. Sobhy, and A. M. Amin, "Unusual cause of pericardial effusion.", BMJ case reports, vol. 2012, 2012. Abstract

A 65-year-old Egyptian lady suffering from non-alcoholic liver cirrhosis was referred to our unit for evaluation of a massive pericardial effusion. Few weeks before presentation, she suffered from progressive abdominal distention and dyspnoea. She denied fever, rigors or other cardiorespiratory symptoms. Examination revealed shrunken liver, spleenomegaly and ascites. Chest was clear to auscultation and heart sounds were distant. Chest radiograph showed cardiomegaly and clear lung fields. Abdominal ultrasound confirmed the results of abdominal examination. Transthoracic echocardiogram (TTE) revealed a massive pericardial effusion (PEF) and rheumatic mitral stenosis. Chest tomography showed PEF and clear lung fields. One litre of exudate was removed via TTE-guided needle pericardiocentesis. A pericardio-peritoneal shunt was suspected, which was confirmed via a radioisotopic study. This case is among very few cases that reported PEF in a cirrhotic ascetic patient secondary to a radio-isotopically confirmed pericardio-peritoneal shunt in the literature.

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