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El-Hadidi, N. M. N., and S. S. Darwish, " Preliminary study on the different effects of consolidation treatments in heartwood and sapwood of a decayed gymnosperm wood", Journal of Archaeological & Restoration Studies (EJARS), vol. 4, issue 1, pp. 1-11, 2014.
Darwish, M. H., A. Hassan, H. A. Khalifa, and I. B. R. A. H. I. M. A. ABU-ELLA, " Proprioception Errors in Patients with Cervical Spondylosis at Sagittal Plane", The Medical Journal of Cairo University, vol. 86, issue 8, pp. 4255-4257, 2018. mjcu_volume_86_issue_december_pages_4255-4257.pdf
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Y, A. W., A. B. A. A. H. S. El-Tahawy NFG, W. N. N. Mohamed HA, and A. L. DA, " Rivastigmine ameliorates gentamicin experimentally induced acute renal toxicity", . Int Immunopharmacology, 2023.
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doss, L., N. Gouda, H. Nassar, and M. elayashy, Surgical transversus abdominis plane (TAP) block for pain relief in children undergoing splenectomy , , Cairo, Cairo University, 2014.
Desouky, F. E. G., M. M. Saadeldin, and E. I. K. Zawawi, " Synthesis and tuning the structure, morphological, optical, and photoluminescence properties of heterostructure cerium oxide and tin oxide nanocomposites", Journal of Luminescence , vol. 241, pp. 118450, 2022.
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I, M., D. A, A. A, H. D, and S. T.M, " THE EFFICACY OF CERVICAL LORDOSIS REHABILITATION FOR NERVE ROOT FUNCTION, PAIN, AND SEGMENTAL MOTION IN CERVICAL SPONDYLOTIC RADICULOPATHY", WCPT, Holland, 21 June 2011. Abstract

Purpose: This study was conducted to test the hypothesis that improvement of cervical lordosis in CSR, using 3-point bending traction, will improve the clinical features in a sample population of patients suffering from Cervical Spondylotic Radiculopathy( CSR )with defined cervical hypo-lordosis.
Relevance: This study assists in the understanding of the association between sagittal curve alignment and lasting improved function providing physiotherapists with a guidelines for proper rehabilitation of CSR.
Participants: Thirty patients with lower CSR and with a cervical hypo-lordosis were included in the study. The patients were assigned randomly into two groups of equal number, study and control groups.
Methods: Both groups received stretching exercises and infrared radiation; additionally the study group received 3 point bending cervical traction. Treatments were applied 3 x per week for 10 weeks after which a 12 week follow up was performed. The peak to peak amplitude of dermatomal somatosensory evoked potentials (DSSEPS), absolute rotation angle (ARA C2-C7), cervical flexion-extension kinematics analysis, and visual analogue scale (VAS) were measured for all patients at three intervals (initial, after 10 weeks of treatment, and at follow up of 3 months).
Analysis: The outcome measure of ARA, pain, peak to peak DSSEPS, and kinematics analysis of cervical spine were measured using repeated measures one-way ANOVA to compare measurements made at three intervals.
Results: In the study group, an increase in cervical lordosis (ARA C2-C7) was found (p< 0.0001, F=49.81) and maintained at follow up. No statistically significant improvement in lordosis was found for the control group. A Significant reduction in VAS for study group after 10 weeks of treatment and at 12 weeks follow up was found. In contrast, there was a less significant decrease in post treatment VAS and the follow up measures revealed a significant increase in the VAS score towards initial baseline values. An inverse linear correlation between increased lordosis and VAS was found (r=-.49; p=0.0059) for both groups initially and maintained in the study group post treatment (r=-.6; p=0.0138). At 10-week follow up, we found statistically significant improvements in DSSEPS for both groups (one way ANNOV, p< 0.0001). However, at 12 week post treatment follow up, only the study group showed statistically significant improvement compared to initial (p < 0.006) whereas the control group values returned to baseline measurement (p<0.153). We identified a linear correlation between initial DSSEPs and ARA for both groups (r=.65; p<0.0001), where as this relationship was only maintained in the study group at final follow-up (r=.55; p=0.033).
Conclusions: Improved lordosis in the study group was associated with significant improvements in nerve root function, VAS rating, and translational and rotational motions of the lower cervical spine. Only in the study group were the results maintained at long-term follow up.
Implications: Appropriate physical rehabilitation for CSR should include cervical sagittal curve correction, as it is may to lead greater and longer lasting improved function.
Key-words: 1. cervical sagittal curve 2. 3-point beding traction 3. DSSEPS
Funding acknowledgements: This study was unfunded.
Ethics approval: institutional review board approval was obtained before the study was initiated from Cairo University´s ethics committee.
Session name:
MUSCULOSKELETAL: Spine 2

Programme track/theme:
Professional Practice - MUSCULOSKELETAL: Spine

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El-Hadidi, N. M. N., and S. S. Darwish, " Use of acids and alkalis in cleaning archaeological wood", International Conference on Giza through the Ages, Faculty of Archaeology, Cairo University, 4-6 March, 2008.
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Davies, J., M. M. Abdel-Wahab, and D. Mckay, " Validation of models for estimating solar radiation on horizontal surfaces.", International Energy Agency Task 1 June , vol. Vol.1, 2, 3, 1988.
Doss, R. W., A. - A. El-Rifaie, Y. M. Gohary, and L. A. Rashed, " Vitamin D Receptor Expression in Vitiligo", indian journal of dermatology, vol. 6, issue 1, pp. 544-548, 2015. vitamin_d_receptor_expression_in_vitiligo.pdf
Kholmurodov, K., E. Dushanov, K. Yasuoka, H. Khalil, A. Galal, S. Ahmed, N. Sweilam, and H. Moharram, ” Molecular dynamics simulation of the interaction of ethanol-water mixture with a Pt surface” Journal of Natural Science, , 2011.
Kholmurodov, K., E. Dushanov, K. Yasuoka, K. Yasuoka, H. Khalil, A. Galal, S. Ahmed, N. Sweilam, and H. Moharram, ” Molecular dynamics study of ethanol solvated by water on the Pt (1 1 1) surface” Journal of Chemical Physics 402, 41–47, , 2012.
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Dixon, S. J., J. Bashutski, M. L. Rütz, H. A. Goldberg, S. M. Sims, A. Gramoun, S. Shorey, M. Manolson, J. N. Heersche, H. Zhang, et al., "The $\alpha$v$\beta$3 integrin as a therapeutic target for inhibition of bone resorption", Arthritis research & therapy, vol. 6, no. Suppl 3: BioMed Central Ltd, pp. 23, 2004. Abstract
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Rezk, M., A. Chandra, D. Addis, H. Møller, M. Youssef, P. Dasgupta, and H. Yamamoto, "() expression as a predictor of oncological outcomes in patients with high-grade prostate cancer treated with primary androgen deprivation therapy: a cohort study.", BMJ open, vol. 9, issue 3, pp. e025161, 2019 Mar 08. Abstract

OBJECTIVES: To determine whether () expression can be used as a biomarker to predict biochemical recurrence and prostate cancer-specific death in patients with high Gleason grade prostate cancer treated with androgen deprivation therapy (ADT) as monotherapy.

METHODS: A multicentre retrospective cohort study identifying 149 patients treated with primary ADT for metastatic or non-metastatic prostate cancer with Gleason score 8-10 between 1999 and 2006. Patients planned for adjuvant radiotherapy at diagnosis were excluded. Age at diagnosis, ethnicity, prostate-specific antigen and Charlson-comorbidity score were recorded. Prostatic tissue acquired at biopsy or transurethral resection surgery was assessed for immunohistochemical expression of . Failure of ADT defined as prostate specific antigen nadir +2. Vital status and death certification data determined using the UK National Cancer Registry. Primary outcome measures were overall survival (OS) and prostate cancer specific survival (CSS). Secondary outcome was biochemical recurrence-free survival (BRFS).

RESULTS: The median OS of our cohort was 60.2 months (CI 52.0 to 68.3). expression observed in 51/149 cases (34%). Multivariate Cox proportional hazards analysis showed no significant association between expression and OS (p=0.41), CSS (p=0.92) and BRFS (p=0.31). Cox regression analysis showed Gleason score (p=0.003) and metastatic status (p<1×10) to be the only significant predictors of prostate CSS.

CONCLUSIONS: No significant association was found between status and any of our outcome measures. Despite a limited sample size, our results suggest that does not appear to be a useful biomarker in predicting response to ADT in patients with high risk prostate cancer.

Ahmed, N. A., N. M. Radwan, K. A. E. S. Ela, A. H. Salam, and H. S. E. Din, "(1989). Effect of long acting injectable contraceptive "Depo-Provera" on the metabolism of some amino acid neurotransmitters in rat brain. Bull. Egypt. Soc. Ph", Bull. Egypt. Soc. Physiol. Sci. , vol. 9, issue 5, pp. 1-26., 1989.
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S.A.Shehata, Y.M.Ahmed, and O. S. Darwish, ). Compost and it's applications ( Effect of rates and time on Snap beans growth), , Germany, LAMBENT Academic publications, 2012.
D.Elgamal, A.Badr, and M.abdelAzeim, ")."New Binary Particle Swarm Optimization with Immunity-Clonal Algorithm", Journal of Computer Science, vol. 9, pp. 1534-1542, 2013. Abstract

Particle Swarm Optimization used to solve a continuous problem and has been shown to perform well however, binary version still has some problems. In order to solve these problems a new technique called New Binary Particle Swarm Optimization using Immunity-Clonal Algorithm (NPSOCLA) is proposed This Algorithm proposes a new updating strategy to update the position vector in Binary Particle Swarm Optimization (BPSO), which further combined with Immunity-Clonal Algorithm to improve the optimization ability. To investigate the performance of the new algorithm, the multidimensional 0/1 knapsack problems are used as a test benchmarks. The experiment results demonstrate that the New Binary Particle Swarm Optimization with Immunity Clonal Algorithm, found the optimum solution for 53 of the 58 multidimensional 0/1knapsack problems.

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Ahmed, A., A. E. Amir, I. Rabee, and S. E. Deeb, ", "Effective Diagnosis of Schistosomiasis haematobium by Immunomagnetic Bead ELISA technique Using Super-Paramagnetic Nanoparticles", ", Journal of American Science, vol. 8, issue 1545-1003, pp. 833-841, 2012.
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Daif, E. T., and et al, "- Response of osseous defects to implanted anorganic xenogenic bone with and without autogenous bone grafts.", Cairo Dental Journal,, vol. 17, pp. 1 - 6, 2001.
Eeian, A. W., E. A. A. Hafez, E. S. Darwish, and M. H. Elnagdi, "- Studies with polyfunctionally substituted heteroaromatics: synthesis of new heterocyclic aromatic amines as potential intermediates for preparation of dyes for thermal diffusion printing, ", Canadian Journal of Chemistry, vol. 76, issue 7, pp. 1038-1041, 1998.
Tawfik, N. M., M. E. Deeb, and A. S. Nasr, "-Role of soluble P-selectin and methylenetetrahydrofolate reductase gene polymorphisms (677C>T) in Egyptian patients with venous thromboembolism.", Blood Coagul Fibrinolysis., vol. 23, issue 6, pp. 537-542, 2012.
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Farag, R. S., Z. Y. Daw, F. M.; Hewedi, and G. S. El-Baroty, ". Antimicrobial activity of some Egyptian spices essential oil.", J. Food Protection, 52, vol. 52, pp. 665-667, 1989.
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