Early language development is stimulated by the linguistic input that children hear on a regular basis. Since media has become an integral part of Egyptian children’s lives in the past decade it is essential to study its role on language development. The aim of this work is to detect the relation between delayed language development and increased exposure to visual media. The study was conducted on 140 Egyptian, Arabic speaking children, with age range between two and five years. The Children were divided into two groups; 70 children with delayed language development, and 70 typically developing children. A questionnaire was designed to assess the media viewing habits of each group. The results obtained from this study revealed an association between early and excessive exposure to visual media and delayed language development.

Key words: Visual media – Television – Language development- Language assessment- Media viewing habits.

This study was conducted on sixty adult albino rats in attempt to evaluate the effect of calcium, vitamink, low intensity laser therapy and their combination on the histopathlogical bony changes in induced osteoporosis. Ten rats were maintained on normal diet, the remaining fifty rats were divided into three groups. Group A was received no drug. Group B was received calcium and subjected to laser on right side. Group C was received calcium and vitamin K and subjected to laser on the right side

Background: Osteoporosis is one of the deleterious side effects of long-term glucocorticoid therapy. The side-effects of the currently available osteoporotic therapies and their ability to increase bone mass is relatively small not more than 2% per year so, there is a need for novel drug therapies for the treatment of osteoporosis. Evidence that osteoporosis and cardiovascular diseases are positively correlated. Therefore, the attention has driven toward the importance of possible synergism that might occur from combination of anti resorpative medications with simvastatin.
Aim of the work: assess the osteomodulatory and cardio vascular protective effect of Simvastatin, residronate, strontium ranelate and raloxifene separately and their combination with simvastatin in rat model of glucocorticoid induced osteoporosis
Methodology: A 72Mature healthy albino rats of both sex are randomly allocated into 9 main groups and received drugs for 6weeks by oral gavage .G1: normal control group,G2:osteoprotic treated group received prednisolone (pred) at 30 mg/kg per 2 days ,G3:Simvastatin(Sim)- treated group received simvastatin at10mg/kg/day,G4:Residronate (Residr)- treated group received residronate at 1mg/kg/day), G5:strontium(SR)-treated group received strontium at 600mg/kg/day,G6:raloxifene(RAL)-treated group, received raloxifene at 1.25mg/kg/day,G7:SIM+Residr-treated group,G8:Sim +SR treated group and G9:Sim +RAL treated group. At the end of 6weeks ,all studied groups were assessed pharmacologically by measurement of mean arterial blood pressure(MAP), ECG and echocardiography, Biochemically, by measurement of serum Ca, P, osteocalcin(OCN), bone specific alkaline phosphatase (BSAP),ALT and AST. Histologically by assessment of bone cortical thickness, histopathological scoring and bone mineral density by DEXA scan was also recorded.

Results: The result revealed Significant elevation of mean arterial blood pressure, decrease in LVEDD , decrease in ejection fraction with decrease in Ach induced aortic relaxation .In addition to the significant elevation of serum BSAP, significant decrease in the serum level of osteocalcin , Ca and compansatory increase in serum level of Pin osteoporotic non treated group as compared to normal control group. Separately treated groups 3,4,5,6 showed significant amelioration of the above mentioned changes with variable degrees, with a net results of enhanced of bone architecture and biochemical markers compared osteoporotic group.

The aim of the present study was to investigate the periodontal regenerative
potential of gingival margin-derived mesenchymal stem/progenitor cells in an
animal model. Periodontal defects were induced at six sites in eight miniature-pigs
in the premolar/molar area. Autologous cells were isolated from the gingival
margin of each animal, magnetically sorted using STRO-1 antibodies and
characterized flow-cytometrically for the expression of CD14, CD31, CD34,
CD45, CD117 and STRO-1. Colony-formation and multilineage differentiation
potential were tested. The cells were expanded ex-vivo and loaded on BioOss®-
(test-group-1)-and Collagen-(test-group-2)-scaffolds and transplanted into the
animals, together with unloaded scaffolds (control-groups-1 and -2), sites
receiving subgingival debridement (control-group-3) and non-treatment controls
(control-group-4). Clinical attachment level (CAL), probing depth (PD), gingival
recession (GR) and subtraction volumetric computed tomography (CT)
examinations were performed at -4 weeks, baseline and 12 weeks. The histological
attachment level (HAL) was evaluated after 12 weeks in each group. Results of
this study revealed that cells were plastic-adherent, showed colony formation,
were CD14-, CD34-, CD45-, CD31+, CD117+, STRO-1+ and could be
differentiated into osteoblastic, adipocytic and chondroblastic directions. Testgroup-
1 and -2 showed considerable gains in CAL, PD, gingival height and HAL.
A significant radiographic defect fill was observed in test -group-1 compared to
control-group-4. In conclusion, mesenchymal stem/progenitor cells from the
gingival cervical margin showed a significant potential in regenerative periodontal
treatment.