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Choucry, M. A., M. N. A. Khalil, and S. A. El Awdan, "Protective action of Crateva nurvala Buch. Ham extracts against renal ischaemia reperfusion injury in rats via antioxidant and anti-inflammatory activities", Journal of ethnopharmacology, vol. 214: Elsevier, pp. 47–57, 2018. Abstract
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Choucry, M. A., A. A. Shalabi, A. M. El Halawany, F. S. El-Sakhawy, A. Zaiter, H. Morita, P. Chaimbault, and E. Abdel-Sattar, "New pregnane glycosides isolated from Caralluma hexagona lavranos as inhibitors of α-glucosidase, pancreatic lipase, and advanced glycation end products formation", ACS omega, vol. 6, issue 29: American Chemical Society, pp. 18881-18889, 2021. Abstract
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Choucry, M. A., N. E. L. M. Fiki, I. A. Shehata, and T. A. Ibrahim, Pharmacognostical and Biological Study of Certain Aloe Species Cultivated in Egypt., , Cairo, Cairo, 2011.
Choucry, M. A., M. M. Shabana, N. E. L. M. Fiki, and I. A. Shehata, "Appropriate Quality Control Procedure OF Herbal Drugs in the Egyptian Market Part 1: Mepaco Sedative Tea Bags.", Bulletin OF Faculty OF pharmacy, Cairo-University., vol. Vol. 38 , issue (3), pp. P.87-102, 2000.
Choucry, M. A., M. M. Shabana, N. E. L. M. Fiki, and I. A. Shehata, "Quality Control OF A Sedative Herbal Drug.", Bulletin OF Faculty OF pharmacy, Cairo-University., vol. 40 , issue (1), pp. P.215-221, 2002.
Choucry, M. A., "Chemical composition and anticancer activity of Achillea fragrantissima (Forssk.) Sch. Bip. (Asteraceae) essential oil from Egypt", Journal of Pharmacognosy and Phytotherapy , vol. Vol. 9, issue (1), pp. 1-5, 2017. paper3_achillea.pdf
Choucry, M. A., M. N. A. Khalil, and S. A. E. Awdan, ": Protective action of Crateva nurvala Buch. Ham extracts against renal ischaemia reperfusion injury in rats via antioxidant and anti-inflammatory activities", Journal of Ethnopharmacology, vol. 214, pp. 45-57, 2018.
Choucry, A. M., M. Y. Al-Shorbagy, A. S. Attia, and H. S. El-Abhar, "Pharmacological Manipulation of Trk, p75NTR, and NGF Balance Restores Memory Deficit in Global Ischemia/Reperfusion Model in Rats.", Journal of molecular neuroscience : MN, vol. 68, issue 1, pp. 78-90, 2019 May. Abstract

Long-term memory impairment is reported in more than 50% of cardiac arrest survivors. Monosialoganglioside (GM1) provided neuroprotection in experimental models of stroke but failed to replicate its promise clinically for unknown reasons. GM1 stimulates the release of nerve growth factor (NGF), which is synthesized as a precursor protein (pro-NGF) that either mediates apoptosis through the p75 neurotrophin receptor (p75NTR) or is cleaved by the protease furin (FUR) to yield mature NGF, the latter supporting survival through tropomyosin kinase receptor (Trk). The flavanol epicatechin (EPI) inhibits p75NTR-mediated signaling and apoptosis by pro-NGF. The aim of the current work is to test whether these two drugs affect, or communicate with, each other in the setting of CNS injuries. Using the two-vessel occlusion model of global ischemia/reperfusion (I/R), we tested if pharmacological modulation of Trk, p75NTR, and NGF balance with GM1, EPI, and their combination, can correct the memory deficit that follows this insult. Finally, we tested if FUR insufficiency and/or p75NTR-mediated apoptosis negatively affect the neurotherapeutic effect of GM1. Key proteins for Trk and p75NTR, FUR, and both forms of NGF were assessed. All treatment regiments successfully improved spatial memory retention and acquisition. A week after the insult, most Trk and p75NTR proteins were normal, but pro/mature NGF ratio remained sharply elevated and was associated with the poorest memory performance. Pharmacological correction of this balance was achieved by reinforcing Trk and p75NTR signaling. GM1 increased FUR levels, while concomitant administration of EPI weakened GM1 effect on pro-survival Trk and p75NTR mediators. GM1 neuroprotection is therefore not limited by FUR but could be dependent on p75NTR. Graphical Abstract "."

Choucry, A. M., M. Y. Al-Shorbagy, A. S. Attia, and H. S. El-Abhar, "Pharmacological Manipulation of Trk, p75NTR, and NGF Balance Restores Memory Deficit in Global Ischemia/Reperfusion Model in Rats.", Journal of molecular neuroscience : MN, vol. 68, issue 1, pp. 78-90, 2019. Abstractchoucry2019_article_pharmacologicalmanipulationoft.pdf

Long-term memory impairment is reported in more than 50% of cardiac arrest survivors. Monosialoganglioside (GM1) provided neuroprotection in experimental models of stroke but failed to replicate its promise clinically for unknown reasons. GM1 stimulates the release of nerve growth factor (NGF), which is synthesized as a precursor protein (pro-NGF) that either mediates apoptosis through the p75 neurotrophin receptor (p75NTR) or is cleaved by the protease furin (FUR) to yield mature NGF, the latter supporting survival through tropomyosin kinase receptor (Trk). The flavanol epicatechin (EPI) inhibits p75NTR-mediated signaling and apoptosis by pro-NGF. The aim of the current work is to test whether these two drugs affect, or communicate with, each other in the setting of CNS injuries. Using the two-vessel occlusion model of global ischemia/reperfusion (I/R), we tested if pharmacological modulation of Trk, p75NTR, and NGF balance with GM1, EPI, and their combination, can correct the memory deficit that follows this insult. Finally, we tested if FUR insufficiency and/or p75NTR-mediated apoptosis negatively affect the neurotherapeutic effect of GM1. Key proteins for Trk and p75NTR, FUR, and both forms of NGF were assessed. All treatment regiments successfully improved spatial memory retention and acquisition. A week after the insult, most Trk and p75NTR proteins were normal, but pro/mature NGF ratio remained sharply elevated and was associated with the poorest memory performance. Pharmacological correction of this balance was achieved by reinforcing Trk and p75NTR signaling. GM1 increased FUR levels, while concomitant administration of EPI weakened GM1 effect on pro-survival Trk and p75NTR mediators. GM1 neuroprotection is therefore not limited by FUR but could be dependent on p75NTR. Graphical Abstract "."

Choucry, M., M. Gonaid, S. M. Ezzat, and O. Eid, Crassulaceae (chemistry and pharmacology)-A review, : ELSEVIER SCIENCE BV, 2018. Abstract
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Choucry, M. A., "Chemical composition and anticancer activity of Achillea fragrantissima (Forssk.) Sch. Bip.(Asteraceae) essential oil from Egypt", Journal of Pharmacognosy and Phytotherapy, vol. 9, no. 1: Academic Journals, pp. 1–5, 2017. Abstract
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Choucair, A., T. H. Pham, S. Omarjee, J. Jacquemetton, L. Kassem, O. Trédan, J. Rambaud, E. Marangoni, L. Corbo, and I. Treilleux, The arginine methyltransferase PRMT1 regulates IGF-1 signaling in breast cancer, , vol. 38, issue 21: Nature Publishing Group, pp. 4015, 2019. Abstract
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Chopra, H., P. S. Dey, D. Das, T. Bhattacharya, M. Shah, S. Mubin, S. P. Maishu, R. Akter, M. H. Rahman, C. Karthika, et al., "Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets.", Molecules (Basel, Switzerland), vol. 26, issue 16, 2021. Abstract

is very well-known medicinal plant not only in the Asian hemisphere but also known across the globe for its therapeutic and medicinal benefits. The active moiety of is curcumin and has gained importance in various treatments of various disorders such as antibacterial, antiprotozoal, cancer, obesity, diabetics and wound healing applications. Several techniques had been exploited as reported by researchers for increasing the therapeutic potential and its pharmacological activity. Here, the dictum is the new room for the development of physicochemical, as well as biological, studies for the efficacy in target specificity. Here, we discussed nanoformulation techniques, which lend support to upgrade the characters to the curcumin such as enhancing bioavailability, increasing solubility, modifying metabolisms, and target specificity, prolonged circulation, enhanced permeation. Our manuscript tried to seek the attention of the researcher by framing some solutions of some existing troubleshoots of this bioactive component for enhanced applications and making the formulations feasible at an industrial production scale. This manuscript focuses on recent inventions as well, which can further be implemented at the community level.

Choi, B. - H., J. - I. Bang, J. - I. Jin, S. - S. Kim, H. - T. Jo, G. K. Deb, N. Ghanem, K. - W. Cho, and I. - K. Kong, "Coculturing cumulus oocyte complexes with denuded oocytes alters zona pellucida ultrastructure in in vitro matured bovine oocytes", Theriogenology, vol. 80, issue 9: Elsevier, pp. 1117-1123, 2013. Abstract
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Choi, J. - H., T. W. Na, M. I. R. Mamun, A. A. M. El-Aty, E. - H. Shin, J. - H. Park, and J. - H. Shim, "Bufferized Solvent Extraction and HPLC Fluorometric Detection Method for Sarafloxacin in Pig and Chicken Muscles", Biomedical Chromatography, 2011. AbstractCU-PDF.pdf

In this study, a method for the detection of sarafloxacin in pig and chicken muscles was developed using HPLC-FLD as a regulatory residue technique. Good extraction efficiency was achieved using a mixture of 1% orthophosphoric acid-0.2 m MgCl(2) in water and acetonitrile as an extraction solvent, and n-hexane partitioning and centrifugation for cleanup was used in the absence of dehydration. Specificity, linearity, detection and quantification limits, recovery, accuracy and precision were all validated, and all results were sufficient for the SARA regulatory residue method in pig and chicken muscles. The method developed and described herein was not only simple but also reliable, and was applied to market samples to determine their residue contents.

Choi, A. S., R. G. Mistrick, H. Xue, M. A. Kassem, S. Kaseb, M. F. El-Refaie, C. Kabre, M. Cheng, G. R. Liu, and K. Y. Lam, vi contents, , 2016. Abstract
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Choi, J. Y., K. T. Desta, V. V. G. Saralamma, S. J. Lee, S. J. Lee, S. M. Kim, A. Paramanantham, H. J. Lee, Y. - H. Kim, H. - C. Shin, et al., "LC-MS/MS characterization, anti-inflammatory effects and antioxidant activities of polyphenols from different tissues of Korean Petasites japonicus (Meowi).", Biomedical chromatography : BMC, vol. 31, issue 12, 2017 Dec. Abstract

The Korean Petasites japonicus is a perennial plant used in folk medicine as a remedy for many diseases and popularly consumed as spring greens. Ten polyphenols were characterized from the leaves, stems and roots of this plant via high-performance liquid chromatography-tandem mass spectrometry. Individual polyphenols were quantified for the first time using calibration curves of six structurally related external standards. Validation data indicated that coefficients of determinations (R2 ) were ≥0.9702 for all standards. Recoveries measured at 50 and 100 mg/L were 80.0-91.9 and 80.3-105.3%, respectively. Precisions at these two concentration levels were 0.7-6.1 and 1.1-5.5%, respectively. The total number of identified components was largest for the leaves and smallest for the stems. The leaf and root polyphenolic extracts showed anti-inflammatory effects by inducing LPS-activated COX-2 and iNOS protein levels in mouse macrophage RAW 264.7 cells. The antioxidant capacity of the polyphenols, when evaluated for DPPH (α,α-diphenyl-β-picrylhydrazyl)ˑ , ABTS+ [2-2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)] and superoxide radical scavenging activities, and in ferric reducing ability of plasma (FRAP) assays, was highest in the leaf and lowest in the stem. This trend suggests that the antioxidant capacities depend primarily on polyphenol concentration in each tissue. The current findings suggest that polyphenols derived from P. japonicas tissues could have potential as functional health foods.

Choi, Y., N. Kim, M. Mannaa, H. Kim, J. Park, H. Jung, G. Han, H. - H. Lee, and Y. - S. Seo, "Characterization of type VI secretion system in Xanthomonas oryzae pv. oryzae and its role in virulence to rice", The plant pathology journal, vol. 36, issue 3: The Korean Society of Plant Pathology, pp. 289, 2020. Abstract
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Choi, J. - H., M. I. R. Mamun, A. A. M. El-Aty, J. - H. Park, E. - H. Shin, J. Y. Park, S. - K. Cho, S. C. Shin, K. B. Lee, and J. - H. Shim, "Development of a Single-Step Precipitation Cleanup Method for the Determination of Enrofloxacin, Ciprofloxacin, and Danofloxacin in Porcine Plasma", Food Chemistry, vol. 127, issue 4, pp. 1878–1883, 2011. AbstractCU-PDF.pdf

In this study, we describe a newly developed and simple analytical method using high-performance liquid chromatography coupled to fluorescence detector (HPLC-FLD) for the determination of enrofloxacin, ciprofloxacin, and danofloxacin in porcine plasma. A single-step sample preparation, including extraction with acidic acetonitrile, coagulation with ammonium acetate, and centrifugation made possible the direct analysis of plasma samples without the need for any further cleanup procedure. The developed method was validated with specificity, linearity, limit of detection (LOD), limit of quantitation (LOQ), accuracy, and precision. All results were fully adequate. In the study using porcine plasma incurring enrofloxacin, the developed method proved capable of quantifying concentrations below its maximum residue limit, and its time-course residues were excreted within the 10-day withdrawal time.

Cho, H. - J., A. M. A. El-Aty, A. Goudah, G. - M. Sung, H. Yi, D. - C. Se, J. - S. Kim, J. - H. Shim, J. - Y. Jeong, S. - H. Lee, et al., "Monitoring of fluoroquinolone residual levels in chicken eggs by microbiological assay and confirmation by liquid chromatography", Biomedical Chromatography, vol. 22, no. 1, pp. 92-99, 2008. AbstractWebsite
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Cho, Y., N. Dixon, R. El-Sherbiny, I. R. Fleming, V. P. Guedes, R. L. S. dos Izzo, E. Kavazanjian Jr, S. M. Merry, W. Powrie, K. Reddy, et al., Geotechnical Characterization, Field Measurement, and Laboratory Testing of Municipal Solid Waste, , 2011. Abstract

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Cho, H. - J., K. Jo, H. Yi, S. M. Cho, A. A. M. El-Aty, M. K. Kim, S. B. Han, J. H. Oh, C. H. Kwon, J. - H. Shim, et al., "Development and Validation of A Liquid Chromatography Method with Electrospray Ionization Tandem Mass Spectrometry for the Determination of Brotizolam Residues in Beef and Commercial Whole Milk", Biomedical Chromatography, vol. 25, issue 9, pp. 1061-6, 2011. CU-PDF.pdf
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