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Aziz, M., A. ElAshmaoui, N. S. Mohamed, and M. M. M. M. M. Mahmoud, "Assessment of skin microcirculation and inflammatory markers of metabolic syndrome in a rat model ", Life Science Journal, 2011;, vol. 8(4):314 -321] (, issue ISSN: 1097-8135)., 2011.
Aziz, R. K., R. A. Edwards, W. W. Taylor, D. E. Low, A. McGeer, and M. Kotb, "Mosaic prophages with horizontally acquired genes account for the emergence and diversification of the globally disseminated M1T1 clone of Streptococcus pyogenes", Journal of bacteriology, vol. 187, no. 10: American Society for Microbiology, pp. 3311–3318, 2005. Abstract
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Aziz, T. A. M., F. A. M. Asmar, T. Moustafa, H. Atta, L. Rashed, D. Sabry, S. Ashour, and A. A. T. Aziz, "Assessment of heme oxygenase-1 (HO-1) activity in the cavernous tissues of sildenafil citrate-treated rats", Asian Journal of Andrology, vol. 9, issue 3, pp. 377–381, 2007. Abstractassessment_of_heme_oxygenase_1_ho_1_activity_in_the_cavernous_t.pdf

Aim: To assess heme oxygenase-1 (HO-1) activity in the cavernous tissues of sildenafil citrate-treated rats.
Methods: One hudred and ninty-two Sprague-Dawley male rats, divided into four equal groups, were investigated. Group 1 the control group, received regular animal chow; group 2 received sildenafil citrate by intragastric tube; group 3 received sildenafil and HO inhibitor (zinc protoporphyrin, ZnPP); and group 4 received sildenafil and nitric oxide synthase (NOS) inhibitor L-nitroaginine methyl ester (L-NAME).Twelve rats from each group were killed after 0.5 h, 1h, 2h and 3h of drug administration. Then HO-1 activity, cGMP levels and NOS enzymatic activity and cGMP concentration increased significantly in sildenafil-treated rats compared to other groups throughout the experiment. Rats receiving either HO or NOS inhibitors showed a significant decrease in these parameters. HO-1 cavernous tissue activity and NOS enzymatic activity demonstrated a positive significant correlation with cGMP levels (r = 0.646, r = 0.612 respectively; P < 0.001).
Conclusion. The action of PDE5 inhibitor sildenafil citrate in the cavernous tissue are partly mediated through the interdependent relationship between both HO-1 and NOS activities.
Keywords. Erectile Dysfunction; heme oxygenase; sildenafil citrate; nitric oxide synthase; carbon monoxide.

Aziz, S. A. E. L., H. S. Hamza, and I. A. Saroit, "An energy-efficient hierarchical routing protocol for wireless sensor networks", Informatics and Systems (INFOS), 2010 The 7th International Conference on: IEEE, pp. 1-7, 2010. Abstract
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aziz, M. A. T., M. E. F. Asmar, H. M. Atta, S. Mahfouz, H. H. Fouad, N. K. Roshdy, L. A. Rashed, D. Sabry, A. A. Hassouna, and F. M. Taha, "Efficacy of Mesenchymal Stem Cells in Suppression of Hepatocarcinorigenesis in Rats: Possible Role of Wnt Signaling", Journal of Experimental & Clinical Cancer Research, pp. 30-49, 2011. AbstractCU-PDF

Background: The present study was conducted to evaluate the tumor suppressive effects of bone marrow derived mesenchymal stem cells (MSCs) in an experimental hepatocellular carcinoma (HCC) model in rats and to investigate the possible role of Wnt signaling in hepato-carcinogenesis.

and Aziz, M.S.E.D.A., E. M. B. M. M. F., "Loss of Excitation Faults Detection in Hydro-Generators Using an Adaptive Neuro Fuzzy Inference System", TELKOMNIKA Indonesian Journal of Electrical Engineering, Vol. 17,, vol. 17, issue 2: Indonisia, 2016. Abstract
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Aziz, T. A., M. A. Aziz, H. H. Fouad, L. A. Rashed, H. Salama, S. Abd-Alla, M. A. A. Wehab, and T. Ahmed, "Interferon-$\alpha$ gene therapy prevents aflatoxin and carbon tetrachloride promoted hepatic carcinogenesis in rats", International journal of molecular medicine, vol. 15, no. 1: Spandidos Publications, pp. 21–26, 2005. Abstract
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Aziz, M. S. A., M. G. Elsoholy, and G. R. Saad, "Preparation and characterization of bio-based polyurethanes obtained from castor oil and poly (3-hydroxybutyrate) and their nanocomposites", Polymer Composites, vol. 39, pp. E489 - E499, 2018. AbstractWebsite
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Aziz, M. T. A., M. F. El-Asmar, A. M. Rezq, M. A. A. Wassef, H. Fouad, N. K. Roshdy, H. H. Ahmed, L. A. Rashed, D. Sabry, F. M. Taha, et al., "Effects of a novel curcumin derivative on insulin synthesis and secretion in streptozotocin-treated rat pancreatic islets in vitro", Chinese medicine, vol. 9, no. 1: BioMed Central, pp. 1–12, 2014. Abstract
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Aziz, R. K., and M. Kotb, "Rise and persistence of global M1T1 clone of Streptococcus pyogenes", Emerging infectious diseases, vol. 14, no. 10: Centers for Disease Control, pp. 1511, 2008. Abstract
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Aziz, R. K., B. Dwivedi, S. Akhter, M. Breitbart, and R. A. Edwards, "Multidimensional metrics for estimating phage abundance, distribution, gene density, and sequence coverage in metagenomes", Frontiers in microbiology, vol. 6: Frontiers Media SA, 2015. Abstract
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Aziz, R. K., R. Saad, and M. R. Rizkallah, "PharmacoMicrobiomics or how bugs modulate drugs: an educational initiative to explore the effects of human microbiome on drugs", BMC Bioinformatics, vol. 12, no. Suppl 7: BioMed Central Ltd, pp. A10, 2011. Abstract
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Aziz, A. S., S. A. Taie, and R. A. El-Khoribi, "The Relation between the Learner Characteristics and Adaptation Techniques in the Adaptive E-Learning Systems", 2020 International Conference on Innovative Trends in Communication and Computer Engineering (ITCE): IEEE, pp. 76-81, 2020. Abstract
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aziz, M. A. T., M. F. El-Asmar, A. M. Rezq, S. M. Mahfouz, M. A. Wassef, H. H. Fouad, H. H. Ahmed, and F. M. Taha, "The effect of a novel curcumin derivative on pancreatic islet regeneration in experimental type-1 diabetes in rats (long term study)", Diabetology & metabolic syndrome, vol. 5, issue 1: BioMed Central Ltd, pp. 75, 2013. Abstract
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Aziz, A. M. T., E. M. F. Asmer, A. Rezk, T. A. Kumosani, S. Mostafa, T. Mostafa, H. Atta, A. A. M. Wassef, H. H. Fouad, L. Rashed, et al., "Novel water-soluble curcumin derivative mediating erectile signaling", J Sex Med, vol. 7, issue 8, pp. 2714-2722, 2010.
Aziz, A. S. A., A. E. Hassanien, S. E. - O. Hanaf, and M. F. Tolba, "Multi-layer hybrid machine learning techniques for anomalies detection and classification approach", Hybrid Intelligent Systems (HIS), 2013 13th International Conference on: IEEE, pp. 215–220, 2013. Abstract
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Aziz, M. M., M. Haroun, and O. M. Gad, "STRONGKIDS nutritional risk score and body mass index in malnourishment risk assessment in critically ill children", Int J Pharm Phytopharm Res, vol. 9, pp. 97–108, 2019. Abstract
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Aziz, A. A., D. M. A. M. Osman, and S. F. el Shafei, "Assessing speech intelligibility in a group of Egyptian dysarthric patients", Egyptian Journal of Otolaryngology, vol. 27 (2), issue July, pp. 49-55, 2012.
Aziz, R. K., J. M. Monk, R. M. Lewis, S. I. Loh, A. Mishra, A. A. Nagle, C. Satyanarayana, S. Dhakshinamoorthy, M. Luche, D. B. Kitchen, et al., "Systems biology-guided identification of synthetic lethal gene pairs and its potential use to discover antibiotic combinations", Scientific reports, vol. 5: Nature Publishing Group, pp. 16025, 2015. Abstract
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Aziz, A. P. E. A., A. P. K. T. Shaker, and D. H. A. M. Salam, "Oral Appliances Versus Continuous Positive Air Pressure in the Management of Snoring and Obstructive Sleep Apnea", EDJ, vol. 55, issue jan, pp. 647-654, 2009. paper-2.pdf
Aziz, M. T. A., M. F. E. Asmar, A. Rezq, T. A. Kumosani, S. moustafa, T. Moustafa, H. Atta, M. A. A. Wassef, H. H. Fouad, L. Rashed, et al., "Novel Water-Soluble Curcumin Derivative Mediating Erectile Signaling.", The journal of sexual medicine, vol. 7, pp. 2714-2722, 2010. Abstractnovel_water-soluble_curcumin_derivative_mediating_erectile_signaling..pdf

Introduction: Curcumin is an inducer of heme oxygenase Enzyme-1 (HO-1) that is involved in erectile signaling via elevating cycle guanosine monophsphate (cGMP) levels.
Aim: To assess the effect of oral administration of a water soluble long-acting curcumin derivative on erectile signaling.
Methods: Two hundred and thirty six male white albino rats were divided into four groups; group 1 (N = 20) includes control. Group 2 (N = 72) was equally divided into four subgroups; subgroup 1 received pure curcumin (10 mg/kg), subgroup 2 received the long-acting cucumin derivative (2 mg/kg), subgroup 3 received the long-acting cucumin derivative (10 mg/kg), and subgroup 4 received sildenafil (4 mg/kg). Subgroups were sacrificed after the first, second, and third hour. Group 3 (N = 72) was equally divided into the same four groups already mentioned and were sacrificed after 24 hours, 48 hours, and 1 week. Group 4 (N = 72) was subjected to intracavernosal presser (ICP)measurements 1 hour following oral administration of the same previous doses in the same rat subgroups.
Main Outcome Measure. cavernous tissue HO enzyme activity, cGMP, and ICP.
Result. In group 2 there was a significant progressive maintained elevation of HO activity and cGMP tissue levels starting from the first hour in subgroup 3 and 4,whereas, the rise in HO activity and cGMP started from second hour regarding the ather rat subgroups. Sildenafil effect decreased after 3 hours. In group 3, there was a significant maintained elevation of HO activity and cGMP tissue levels extended to 1 week as compared to controls for all rat subgroups that received both forms of curcumin. In group 4, long-acting cucumin derivative exhibited more significant potentiation of intracavernosal pressure as compared to control and to the pure curcumin.
Conclusion. Water-soluble long-acting curcumin derivative could mediate erectile function via upregulating cavernous tissue cGMP. Abdel Aziz MT, El Asmar MF, Rezq A, kumosani TA, Moustafa S, Moustafa T, Atta H, Abdel Aziz Wassef M, Fouad HH, Rashed L, Sabry D, HAssouna AA, Senbel A, and Abdel Aziz A. Novel Water-Soluble Curcumin Derivative Mediating Erictile Signaling.
Keywords. Diferuloylmethane; cGMP; Heme Oxygenase; Carbon Monoxide System; Erectile Function; Erectile Dysfunction; Corpus Cavernosum; Intracavernosal Pressure.

Aziz, M. S. A., and H. E. Salama, "Biocompatible and antimicrobial carboxymethyl xanthan/zinc physical hydrogels", Polymer Bulletin, vol. 79, issue 5, pp. 3219 - 3231, 2022. AbstractWebsite
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Aziz, M. T. A., M. F. El-Asmar, T. Mostafa, H. Atta, M. A. A. Wassef, H. H. Fouad, N. K. Roshdy, L. A. Rashed, and D. Sabry, "Effects of nitric oxide synthase and heme oxygenase inducers and inhibitors on molecular signaling of erectile function", Journal of Clinical Biochemistry and Nutrition, vol. 37, no. 3: SOCIETY FOR FREE RADICAL RESEARCH JAPAN, pp. 103–111, 2005. Abstract
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Aziz, A. A., A. r Mohamed, and A. M. Gad, "comparative study between anatomic single bundle and anatomic double bundle ACL reconstruction", Egyption arthroscopy association international congress, Cairo, february, 2013.
Aziz, M. S. A., and H. E. Salama, "Effect of vinyl montmorillonite on the physical, responsive and antimicrobial properties of the optimized polyacrylic acid/chitosan superabsorbent via Box-Behnken model", International Journal of Biological Macromolecules, vol. 116, pp. 840 - 848, 2018. AbstractWebsite
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