Publications

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Aziz, A. 10 S. S., and et al, "Inelastic interaction of 4.5 A GeV/c /nucleon He3 with emulsion", Acta Phys-Hungarica , vol. 71, issue 1-2, pp. 827, 1992.
Aziz, A. E., M. Talaat, E. Asmer, M. Farid, T. Mostafa, H. Atta, S. Mahfouz, H. Fouad, L. Rashed, and D. Sabry, "Effects of Losartan, HO‐1 Inducers or HO‐1 Inhibitors on Erectile Signaling in Diabetic Rats", The journal of sexual medicine, vol. 6, issue 12: Blackwell Publishing Inc, pp. 3254-3264, 2009. Abstract
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Aziz, R. K., and M. Kotb, "Integrating proteomics, genomics, and bioinformatics tools to define unique features of the clonal M1T1 strain of Streptococcus pyogenes", International Congress Series, vol. 1289: Elsevier, pp. 175–179, 2006. Abstract
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Aziz, A. E., M. Talaat, E. Asmer, M. Farid, T. Mostafa, H. Atta, S. Mahfouz, H. Fouad, L. Rashed, D. Sabry, et al., "Effects of losartan, HO-1 inducers or HO-1 inhibitors on erectile signaling in diabetic rats", The journal of sexual medicine, vol. 6, no. 12: Wiley Online Library, pp. 3254–3264, 2009. Abstract
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Aziz, M. S. A., and H. E. Salama, "Developing multifunctional edible coatings based on alginate for active food packaging", International Journal of Biological Macromolecules, vol. 190, pp. 837 - 844, 2021. AbstractWebsite
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Aziz, M. S. A., H. F. Naguib, and G. R. Saad, "Nanocomposites based on chitosan-graft-poly(N-Vinyl-2-Pyrrolidone): Synthesis, characterization, and biological activity", International Journal of Polymeric Materials and Polymeric Biomaterials, vol. 64, issue 11, pp. 578 - 586, 2015. AbstractWebsite
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Aziz, R. K., and V. Nizet, "Pathogen microevolution in high resolution", Science translational medicine, vol. 2, no. 16: American Association for the Advancement of Science, pp. 16ps4–16ps4, 2010. Abstract
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Aziz, M., H. Saleh, and A. Abd El-Rahman, "Development of a novel thermoacoustic flue-gas analyzer", AIP Advances, vol. 10, no. 11, pp. 115215, 2020. AbstractWebsite
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Aziz, R. K., "Toxicomicrobiomics: Narrowing the Gap Between Environmental and Medicinal Toxicogenomics", OMICS: A Journal of Integrative Biology, vol. 22, no. 12: Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New …, pp. 788–789, 2018. Abstract
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Aziz, M. A. - E., M. R. Ali, K. S. M. Hammad, and N. F. S. Morsy, "Carboxymethyl cellulose coating enriched with Oregano (Origanum vulgare L.) essential oil to preserve Eel (Anguilla anguilla) fillets during cold storage", Egyptian Journal of Nutrition, vol. 34, issue 2, pp. 1-35, 2019.
Aziz, A. A., D. M. A. M. OSman, A. M. Amin, N. T. Nesim, and M. A. Mohamed, "Effects of superior laryneal nerce block using two different concentrations of ripovacaine on voice and swallowing during office-based laryngeal biospy", Kasr El-Aini Medical Journal, vol. 10 (5), issue Sup., pp. 211-219, 2004.
Aziz, A. M. T., T. Mostafa, H. Atta, L. Rashed, S. A. Marzouk, E. M. Obaia, D. Sabry, A. A. Hassouna, A. M. El-Shehaby, and A. A. T. Aziz, "Oral phosphodiesterase-5 inhibitors: effect of heme oxygenase inhibition on cGMP signaling in rat cavernous tissue.", Journal of Andrologia, vol. 39, issue 2, pp. 66-70, 2007. oral_pde-5.pdf
Aziz, A. A. B., E.S.Hegazi, T. A. Yehia, N. E. Kassim, and T. S. M. Mahmoud, "Growth, Flowering and Fruiting of Manzanillo Olive Trees as Affected by Benzyladenine", Journal of Horticultural Science & Ornamental Plants, vol. 3, issue 3, pp. 244-251., 2011.
aziz, M. A. T., M. F. El-Asmar, H. M. Atta, Y. H. Nassar, O. G. Shaker, M. M. Abd El-Fattah, A. K. El-Ansary, H. H. Fouad, N. K. Roshdy, H. A. Hosni, et al., "Gene expression of heme oxygenase-1: Relationship to fibrogenic and apoptotic factors in murine schistosomiasis", Journal of Clinical Biochemistry and Nutrition, vol. 36, no. 3: SOCIETY FOR FREE RADICAL RESEARCH JAPAN, pp. 67–78, 2005. Abstract
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Aziz, A. S. S., M. H. M. Soleiman, and M. M. Mohery, "Studies of Emitted Particles in Nucleus-Nucleus Interactions at 4.5 AGeV/c.", 4th International Conference on Modern Trend in physics Research, Cairo University, 5 DECEMBER, 2010.
Aziz, R. A. E. L., M. S. E. L. Hawary, S. A. E. L. Ezz, and S. A. E. Atty, "Serum copper, ceruloplasmin and magnesium in type II diabetes mellitus", The Egyptian Journal Of Internal Medicine, vol. 10, issue 4, pp. 67-73, 2000.
Aziz, A. S. A., S. E. - O. Hanafy, and A. E. Hassanien, "Multi-agent artificial immune system for network intrusion detection and classification", 9th International Conference on Soft Computing Models in Industrial and Environmental Applications, Bilbao, Spain, 25th - 27th Jun, 2014.
Aziz, H. A., "Application of Different Body Fluids on Sysmex XE-5000", Egyptian Laboratory Mediceine, vol. 1, pp. 1- 6, 2014.
Aziz, A. M. T. A., H. M. E. Zahed, S. H. Ahmed, and W. Fathy, "Occupational Exposure to Heavy Metal Initiate Carcinogenesis Though BRAF/KRAS Over Expression and DNA Methylation.", Journal of Chemical Health Risks , 2020. Abstract

Colorectal cancer (CRC) is a leading cause of death especially in industries worker.
The aim of this study: is to identify the role of heavy elements exposure on CRC DNA methylation.
Methods: The study was conducted on 25 CRC patients. Biopsies were taken by colonoscopy from malignant tissue and adjacent normal tissues for comparative assessment of BRAF/KRAS, methylated MLH1 and MGMT between the normal and malignant tissues by using real time PCR. In an attempt to identify wither heavy metal like Lead, Aluminum and Mn have a role in cancer development or not, we compared their levels in the serum of 25 CRC patients and 25 normal volunteers by using atomic absorption.
Results: The expressions of BRAF/KRAS, methylated MLH1 and MGMT were significantly higher in malignant tissues compared to normal tissues (p value<0.001). Additionally, the levels of lead and aluminum but not Mn were significantly higher in CRC patients compared to normal controls (p value<0.001). Lead and Aluminum were positively correlated with all studied parameters.
Conclusion: Heavy metals act as starting signals for carcinogenesis through DNA methylation.
Keywords: Colorectal cancer; Heavy metals; DNA methylation.

Aziz, D. E., A. A. Abdelbary, and A. I. Elassasy, "Implementing Central Composite Design for Developing Transdermal Diacerein-Loaded Niosomes: Ex vivo Permeation and In vivo Deposition", Current Drug Delivery, vol. 15, pp. 1330-1342, 2018.
Aziz, M. S. A., M. Elsamahy, M. A. M. Hassan, and F. Bendary, "Loss of excitation faults detection in hydro-generators using an adaptive neuro fuzzy inference system", Indonesian Journal of Electrical Engineering and Computer Science, vol. 1, no. 2, pp. 300-309, 2016. AbstractWebsite
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Aziz, M. S. A., and H. E. Salama, "Development of alginate-based edible coatings of optimized UV-barrier properties by response surface methodology for food packaging applications", International Journal of Biological Macromolecules, vol. 212, pp. 294 - 302, 2022. AbstractWebsite
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Aziz, S. G., O. I. Osman, S. A. Elroby, W. M. I. Hassan, A. Jedidi, and R. H. Hilal, "Proton-coupled electron transfer in dye-sensitized solar cells: a theoretical perspective", Struct Chem, vol. 29, issue 4, pp. 983-997, 2018.
Aziz, M. S. A., H. F. Naguib, and G. R. Saad, "Non-isothermal crystallization kinetics of bacterial poly(3- hydroxybutyrate) in poly(3-hydroxybutyrate-co-butylene adipate) urethanes", Thermochimica Acta, vol. 591, pp. 130 - 139, 2014. AbstractWebsite

The non-isothermal melt crystallization kinetics of a series of copoly(ester-urethane)s, PUs, based on poly(3-hydroxybutyrate), PHB, and poly(butylene adipate), PBA, of different PHB content 20, 40, and 60 wt% were studied using DSC at different cooling rates. Various macrokinetic models, namely, Avrami, Tobin, Ozawa, and Mo models were applied to describe the crystallization process of PHB in the PU matrices. Avrami, Tobin, and Mo models could successfully describe the non-isothermal crystallization behavior of PHB segments in all samples, while Ozawa model provides a fair description of the non-isothermal crystallization process of PUs containing only 20 and 40 wt% PHB. The Avrami exponent was found to range from 3.6 to 4.0, while the Tobin exponent was found to range from 2.3 to 3.0. The spherulites shape and size were analyzed using polarized optical microscopy (POM). The results of kinetic parameters showed that the crystallization rate of PHB segments in the investigated PUs was increased with increasing the PHB content. The isoconversional method of Friedman was used to determine the effective activation energy of crystallization of the PUs and the Lauritzen-Hoffman parameters (Kg and U*) were calculated by applying the Vyazovkin method. © 2014 Elsevier B.V. All rights reserved.

Aziz, A. S. A., and A. E. Hassanien, "Multilayer Machine Learning-Based Intrusion Detection System", Bio-inspiring Cyber Security and Cloud Services: Trends and Innovations: Springer Berlin Heidelberg, pp. 225–247, 2014. Abstract
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