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Azim, H. A., Y. S. E. D. Abdal-Kader, M. M. Mousa, R. A. Malek, M. K. Abdalmassih, and N. Y. Ibrahim, Taxane-based regimens as adjuvant treatment for breast cancer: a retrospective study in egyptian cancer patients, , vol. 16, pp. 65 - 69, 2015. Abstract
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Azim, [2] A. A. Y., A. S. Hanafy, G. M. Mostafa, and E. E. Khalil, "Enhanced Subcooled Flow Boiling of Water by Using Internal Surface Coating", 9th Annual International Energy Conversion Engineering Conference (AIAA), San Diego, 3 August, 2011.
Azim, H. A., L. Kassem, I. Treilleux, Q. Wang, M. A. E. Enein, S. E. Anis, and T. Bachelot, Analysis of PI3K/mTOR Pathway Biomarkers and Their Prognostic Value in Women with Hormone Receptor–Positive, HER2-Negative Early Breast Cancer, , vol. 9, issue 2: Elsevier, pp. 114 - 123, 2016. Abstract
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Azim, H. A., L. Santoro, R. G. Bociek, S. Gandini, R. A. Malek, and J. H.A. Azim, "High dose intensity doxorubicin in aggressive non-Hodgkin's lymphoma: a literature-based meta-analysis ", Annals of Oncology, vol. 21, issue 5, pp. 1064-1071, 2010.
tarek Azim, "Charginos and Z-gauge boson production at e+ e- supercollider", International conference on modem development in elementary particles physics, pp. 36, 1999.
Azim, H. A., L. Kassem, I. Treilleux, Q. Wang, M. A. E. Enein, S. E. Anis, and T. Bachelot, "Analysis of PI3K/mTOR Pathway Biomarkers and Their Prognostic Value in Women with Hormone Receptor–Positive, HER2-Negative Early Breast Cancer", Translational Oncology, vol. 9, issue 2, pp. 114-123, 2016.
Azim, H. A., A. Omar, H. Atef, H. Zawahry, M. K. Shaker, A. H. K. Abdelmaksoud, M. EzzElarab, O. Abdel-Rahman, M. Ismail, and L. Kassem, Sorafenib plus tegafur–uracil (UFT) versus sorafenib as first line systemic treatment for patients with advanced stage HCC: a Phase II trial (ESLC01 study), , vol. 5: Dove Press, pp. 109, 2018. Abstract
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Azim, H. A., S. Lasheen, and L. Kassem, Treatment of HER 2‐positive early breast cancer: How to best balance efficacy and toxicity?, , vol. 24, issue 4, pp. 459 - 461, 2018. Abstract
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Azim, S. A. A., H. A. Darwish, M. Z. Rizk, S. A. Ali, and M. O. Kadry, "Amelioration of titanium dioxide nanoparticles-induced liver injury in mice: possible role of some antioxidants.", Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, vol. 67, issue 4, pp. 305-14, 2015 Apr. Abstract

This study investigates the efficacy of idebenone, carnosine and vitamin E in ameliorating some of the biochemical indices induced in the liver of titanium dioxide nanoparticles (TiO2 NPs) intoxicated mice. Nano-anatase TiO2 (21 nm) was administered (150 mg/kg/day) for 2 weeks followed by the aforementioned antioxidants either alone or in combination for 1 month. TiO2 NPs significantly increased serum liver function enzyme activities, liver coefficient and malondialdehyde levels in hepatic tissue. They also suppressed hepatic glutathione level and triggered an inflammatory response via the activation of macrophages and the enhancement of tumor necrosis factor-α and interleukin-6 levels. Moreover, the mRNA expression of nuclear factor-erythroid-2-related factor 2, nuclear factor kappa B and Bax was up-regulated whereas that of Bcl-2 was down-regulated following TiO2 NPs. Additionally, these NPs effectively activated caspase-3 and caused liver DNA damage. Oral administration of idebenone (200mg/kg), carnosine (200mg/kg) and vitamin E (100mg/kg) alleviated the hazards of TiO2 NPs with the combination regimen showing a relatively higher effect. The histopathological examination reinforced these findings. In conclusion, oxidative stress could be regarded as a key player in TiO2 NPs-induced liver injury. The study also highlights the anti-inflammatory and the anti-apoptotic potentials of these antioxidants against the detrimental effects of TiO2 NPs.

tarek Azim, "Pair production of Charginos in e + e- annihilation at high energies ", Mod. Phys. Lett., vol. 7, issue 17, pp. 1535, 1992.
tarek Azim, "Production of Z-Boson and vv pair", Journal of the faculty of education, vol. 4, issue 16, pp. 16, 1991.
Azim, H. A., and A. S. Ibrahim, Breast cancer in Egypt, China and Chinese: statistics and beyond, , vol. 6, issue 7: AME Publications, pp. 864, 2014. Abstract
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Aziz, A. E., M. Talaat, E. Asmer, M. Farid, T. Mostafa, H. Atta, S. Mahfouz, H. Fouad, L. Rashed, D. Sabry, et al., "Effects of losartan, HO-1 inducers or HO-1 inhibitors on erectile signaling in diabetic rats", The journal of sexual medicine, vol. 6, no. 12: Wiley Online Library, pp. 3254–3264, 2009. Abstract
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Aziz, H. A., "Routine Use of Mini-pool Nucleic Acid Testing (MP-NAT) Multiplex Assay for Sero-negative Blood Donors", Journal of the Egyptian Society of Haematology & Research,, vol. 7, No 2, September, pp. 1-5, 2011.
aziz, M. A. T., T. Mostafa, H. Atta, M. A. Wassef, H. H. Fouad, L. A. Rashed, and D. Sabry, "Putative role of carbon monoxide signaling pathway in penile erectile function", The Journal of Sexual Medicine, vol. 6, no. 1: Elsevier, pp. 49–60, 2009. Abstract
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Aziz, M. S. A., H. E. Salama, and M. W. Sabaa, "Biobased alginate/castor oil edible films for active food packaging", LWT, vol. 96, pp. 455 - 460, 2018. AbstractWebsite
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Aziz, M. T., M. F. Al-Asmar, T. Mostafa, H. Atta, L. Rashed, D. Sabry, S. Ashour, and A. T. Aziz, "Assessment of heme oxygenase-1 (HO-1) activity in the cavernous tissues of sildenafil citrate-treated rats.", Asian J Andrology, vol. 9, issue 3, pp. 377-381, 2007.
Aziz, T. A., M. A. Aziz, H. H. Fouad, L. A. Rashed, H. Salama, S. Abd-Alla, M. A. A. Wehab, and T. Ahmed, "Interferon-alpha gene therapy prevents aflatoxin and carbon tetrachloride promoted hepatic carcinogenesis in rats.", International journal of molecular medicine, vol. 15, issue 1, pp. 21-6, 2005 Jan. Abstract

Retrovirus-mediated interferon alpha (IFN-alpha) gene transfer was evaluated with regard to its possible protective effects against aflatoxin B1 (AFB1)-initiated and carbon tetrachloride (CCl4)-promoted hepatic carcinogenesis in rats. To our knowledge, this is the first time an experimental in vivo gene therapy trial was conducted in Egypt. Two genes were examined in liver tissue by RT-PCR: the first was glutathione-S-transferase placental (GST-P) isoenzyme, as an early marker to detect hepatic malignancy; the second was IFN-alpha gene expression to detect the efficiency of gene uptake and its persistence after transduction. Forty male rats, divided equally into 4 groups, were included in the study: the first group was the control; the second group received CCl4 0.2 ml subcutaneously twice weekly for 12 weeks and AFB1 0.25 mg/kg body wt intraperitoneally twice weekly for 6 weeks; the third group received IFN-alpha (10(8) pfu) intravenously in the tail vein prior to the start of CCl4 and AFB1 injections; and the fourth group received IFN-alpha (10(8) pfu) by intrahepatic injection under ultrasonography guide after termination of the CCl4 and AFB1 injection schedule. The results showed that IFN-alpha has a marked and significant protective effect against hepatic fibrogenesis as well as hepatic carcinogenesis. Pathological examination of liver tissue proved that IFN-alpha minimized both fibrotic and cirrhotic processes. The amount of fibrosis was less in both groups receiving IFN-alpha, with more protection in the group that received IFN-alpha intravenously prior to CCl4 and AFB1. The results of RT-PCR showed that the IFN-alpha gene was significantly expressed in both groups receiving IFN-alpha, with a more intense expression in the group that received IFN-alpha by intrahepatic injection after termination of CCl4 and AFB1 injections. The IFN-alpha gene was detected after three months of gene transduction in rats receiving IFN-alpha intravenously prior to CCl4 and AFB1 and after one month of gene transduction in the post CCl4 and AFB1 rats. IFN-alpha gene was not expressed in the two groups that did not undergo gene transfer. Histopathological signs of premalignant macronodules were evident in the group receiving CCl4 and AFB1, but not IFN-alpha as well as in the group that received IFN-alpha at the end of the experiment. GST-P gene expression was also detected in these two groups, confirming early malignant transformation. In conclusion, IFN-alpha exerts significant protective effects, but more so when the gene is administered before fibrogenic and carcinogenic induction in hepatic tissues. IFN-alpha gene therapy may be justified in clinical trials for high-risk candidates with hepatic carcinogenesis.

Aziz, R. K., and L. K. Mcneil, "Reconstructing the virulome of the human pathogen Streptococcus pyogenes using NMPDR subsystems-based annotation", BMC Bioinformatics, vol. 10, no. Suppl 7: BioMed Central Ltd, pp. A7, 2009. Abstract
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Aziz, A. 10 S. S., and et al, "Inelastic interaction of 4.5 A GeV/c /nucleon He3 with emulsion", Acta Phys-Hungarica , vol. 71, issue 1-2, pp. 827, 1992.
Aziz, M. S. A., M. G. Elsoholy, and G. R. Saad, "Preparation and characterization of bio-based polyurethanes obtained from castor oil and poly (3-hydroxybutyrate) and their nanocomposites", Polymer Composites, vol. 39, pp. E489 - E499, 2018. AbstractWebsite

Bio-based polyurethanes (PUs) were synthesized from castor oil (CO) and poly(3-hydroxybutyrate)-diol (PHB-diol) using 1,6-hexamethylene diisocyanate, as nontoxic connecting agent. The PHB content in the obtained PUs was adjusted from 0 to 60.0 wt%. The synthesis was carried out by one pot solution polymerization. PUs nanocomposites loaded with different contents of cloisite®25A (C25A) were prepared by means of in situ solution polymerization. The molecular structure of the obtained PUs was confirmed by FT-IR. The thermal properties of the neat PUs and the resulting nanocomposites were investigated using DSC and TGA. It was found that the cold crystallization of the PHB component was enhanced, while its melt crystallization was retarded with increasing its own content in the PUs. The incorporated C25A in the PU matrix shifted the cold crystallization peak to higher temperature. TGA studies reveal that neat PUs and nanocomposites exhibited three main decompositions steps. The thermal stability of the neat PUs decreased with increasing the PHB content and increased with increasing the C25A content. Tensile mechanical testing revealed that increasing the content of the PHB and C25A made the PUs rigid and strong. The elastic modulus and ultimate tensile strength of the neat PUs were found to increase with increasing the PHB content and enhanced with incorporation of C25A, while the elongation decreased with increasing the PHB and C25A content. The equilibrium swelling in 1,2-dichloroethane decreased with increasing both the PHB and C25A content in PU matrix. POLYM. COMPOS., 39:E489–E499, 2018. © 2017 Society of Plastics Engineers. © 2017 Society of Plastics Engineers

Aziz, R. K., D. Bartels, A. Best, M. DeJongh, T. Disz, R. Edwards, K. Formsma, S. Gerdes, E. Glass, M. Kubal, et al., "The RAST Server: rapid annotations using subsystems technology", BMC genomics, vol. 9, no. 1: BioMed Central Ltd, pp. 75, 2008. Abstract
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Aziz, S. G., W. I. Hassan, S. K. Alrouby, A. Alyoubi, and R. Hilal, "Ultrafast radiationless decay mechanisms through conical intersections in cytosine. A new semi-planar conical intersection", Indian J. Chem. A, vol. 53A, pp. 143-151, 2014.
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