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Seleem, H., T. ElNahas, and M. Mostafa, 1. THE EFFICACY AND TOXICITY OF OXALIPLATIN, 5-FLUOROURACIL AND LEUCOVORIN AS ADJUVANT TREATMENT IN PATIENTS WITH COLON CANCER, , 1. Abstract

Background: Although surgical resection is still the only curative maneuver in the treatment of colon cancer,
yet efforts have proved that systemic chemotherapy in the adjuvant setting improves the curative rate for those
patients with localized colon cancer. The combination of 5-fluorouracil (5-Fu) and leucovorin (LV) was the
reference treatment. However the advantage of infusional 5-Fu/LV with oxaliplatin (FolFox-4) as adjuvant
treatment for high risk colon cancer patients may change the paradigm soon. In this study we presented our
treatment results for patients with colon cancer treated with FolFox- 4 regimen as adjuvant treatment at Kasr Al
Aini Hospital.
Patients and Methods: We enrolled 55 patients who had undergone curative resection for sage II and III colon
cancer to receive FolFox-4 regimen for six months. The primary end point was disease –free survival
Results: Fifty five patients were included in this study. At the time of analysis (median follow up 18 months)
9 patients (16%) had disease relapse or metastasis. At 2.5 years DFS rates and OAS rates were 75% and 80%,
respectively. The treatment was generally well tolerated with most common grade 1 treatment-related adverse
event being peripheral neuropathy and hematological toxicity.
Conclusion: It is now acceptable to consider combination chemotherapy with FolFox -4 as adjuvant treatment
for high risk colon cancer patients after curative surgery at Kasr El Ainy center of Radiation Oncology and
nuclear medicine

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Ahmed, H. H.;, N. Taha;, A. M. El-Nahla;, and S.A.Essawy, "Effect of modulating prolactin level by neurotransmitters and exogenous prolactin on testosterone level in male rats.", . ESARF and Fac. Vet. Med., Alex Univ., First annual Congreaa, Edfina., pp. 24-26, 89.
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Alkady, O. H., H. G. Metwally, Hany A Abdelsalam, A. M. Hassan, Osama H Abdel-salam, and A. A. Saleh, "Comparison Treatment of Vitiligo by Co-culture of Melanocytes Derived from Hair Follicle with Adipose-Derived Stem Cells with and without NB-UVB", Journal of Pigmentary Disorders , vol. 4, issue 1, 201.
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Chapman, J. B., K. Pohlmann, G. Pohll, A. E. Hassan, P. Sanders, M. Sanchez, and S. Jaunarajs, "Remediation of the Faultless Underground Nuclear Test: Moving Forward in the Face of Model Uncertainty", Waste Management Conference, WM'02, Session 28A, paper 456, Tucson, Arizona, USA, 24-28 February, 202.
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Hassan, A. S., S. M. Assar, and K. A. Ali, "The complementary Poisson-Lindley class of distributions", International Journal of Advanced Statistics and Probability, vol. 3, issue 2, pp. 146-160, 205. complementary_poisson-lindley.pdf
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Elhariri1, M., Y. S. Aleslamboly, M. A. Elshate, R. Elhelw, and M. K. Refai, "Rapid Salmonella Detection in Different Food Detection in Different Food Detection in Different Food Detection in Different Food", BIOSCIENCE RESEARCH , vol. 14, issue 4, pp. : 1005-1010, 207. salmonella_paper.pdf
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Issa, Y. M., W. F. El-Hawary, A. F. A. Youssef, and A. R. Senosy, "Spectrophotometric Determination of Sildenafil Citrate in Pure Form and in Pharmaceutical Formulation Using Some Chromotropic Acid Azo Dyes", Spectrochim. Acta Part A, vol. 75, issue 4, pp. 1297-1303, 210.
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Essa, E. - S. M. M., M. A. S. Aboelela, and M. A. M. Hassan, "Application of Fractional Order Controllers on Experimental and Simulation Model of Hydraulic Servo System", Fractional Order Control and Synchronization of Chaotic Systems, Switzerland, Springer International Publishing, 217.
Henfwi, G. E., "pilgrimage (Hajj) and Pilgrimages in India: the impact of Pilgrimage on the Indian Characters", THAQAFAT UL HIND, vol. 68, issue 2, pp. 97-138, 217.
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Kamal, H., "A Century of Egyptian Women's Demands: The Four Waves of the Egyptian Feminist Movement", Advances in Gender Research, vol. 21, pp. 3-22, 296.
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Miller, S. A., D. D. D., and H. F. Polesky, "(1988). A simple salting out procedure for extracting DNA from human nucleated cells.research,", Nucleic acids, vol. 16, no. (3),, 1215. Abstract
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Miller, S. A., D. D. D., and H. F. Polesky, "(1988). A simple salting out procedure for extracting DNA from human nucleated cells.research,", Nucleic acids, vol. 16, no. (3),, 1215. Abstract
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