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2022
Kloss, P., H. A. Khalil, and A. Lotfata, "Greenery Measures to Mitigate Urban Heat Island Effect in Unplanned Areas: Imbaba, Giza, Egypt", Remapping Urban Heat Island Atlases in Regenerative Cities: IGI Global, 2022.
El-Hadad, G., A. A. Farid, A. M. El Amir, and N. A. Madbouly, "Hazard Effects of Chronic consumption of Sucralose and Saccharin-Sodium Cyclamate Mixture in Murine Model", Egyptian Journal of Chemistry , vol. 65, issue 5, pp. 279-289, 2022.
Hossain, M. F., S. H. Badawy, R. A. El-Motaium, H. M. Abdel-Lattif, and S. M. A., "Health Risk Assessment and Nickel Content in Soils, Rice (Oryza Sativa L.) and Wheat (Triticum Aestivum L.) Grown in Damietta Governorate, Egypt", Environment and Pollution , vol. 11, issue 2, pp. 1-18, 2022.
Kotb, M. A., F. Mostafa, M. Khalil, M. AbdelRaouf, L. Ammar, and N. Sabry, "Hepatitis Post Cardiopulmonary Bypass in Children: Single Center Experience in Egypt", Pediatric Sciences Journal, vol. 2, issue 1, pp. 82-88, 2022. cupsj_volume_2_issue_1_pages_82-88.pdf
Elbakry, H. F., H. A. R. A. Salam, S. saeid Abdelgayed, and Doha A. Mohamed, "Hepatorenal Protective Effects of Sesame Seeds Oil, Flaxseed Oil and Their Mixture Against Methotrexate Toxicity in Rats", Iranian Journal of Toxicology, 2022. ijt-v0n0p0-en.pdfijt-v16n1p51-en.pdf
Gamal, N. G., R. M. Abdel-Salam, L. N. Gadelrub, O. A. Ahmed-Farid, and M. T. Khayyal, "The herbal preparation STW 5 affects serotonergic pathways in the brain and colon as well as stress parameters in experimental irritable bowel syndrome.", Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, vol. 34, issue 4, pp. e14301, 2022. Abstract

BACKGROUND: Exposure to stress has been related to disturbance in 5-hydroxytryptamine (5-HT) signaling in the brain-gut axis and is considered as a major predisposing factor for the development of irritable bowel syndrome (IBS). The present study aimed to investigate the possible involvement of 5-HT and some other stress-related parameters in the effectiveness of STW 5 against stress-induced IBS.

METHODS: Rats were subjected to restraint stress (RS) for 1 h/day for 14 consecutive days to induce IBS-like symptoms and were given STW 5 orally at the same time. At the end of the experiment, blood samples were withdrawn, then animals were euthanized and the brain hippocampi, cerebral cortices, as well as colons were isolated for biochemical and histopathological assessments.

RESULTS: RS increased the plasma corticotrophin releasing factor (CRF) with concomitant increase in hippocampal and cortical 5-HT levels, as well as mast cell inflammatory mediators, oxidative stress biomarkers, and histopathological inflammatory changes observed in rat colon. It also decreased the colonic content of 5-HT with consequent decrease in fecal pellet output (FPO). Treatment with STW 5 protected against these changes.

CONCLUSION: The protective effect of STW 5 against RS-induced IBS is related to its ability to normalize the induced changes in 5-HT in the brain-gut axis and counteract the stress-induced oxidative stress and inflammation.

Nahass, Y. E. H., H. A. Nader, S. Sabet, H. A. Nooh, H. Bassiony, M. Kamel, M. O. H. A. M. E. D. A. Samra, H. K. Mahmoud, W. E. H. Metnawy, and F. E. A. Refaey, "High Frequency of ASXL1 and IDH Mutations in Young Acute Myeloid Leukemia Egyptian Patients", Asian Pacific Journal of Cancer Prevention, vol. 23, issue 3, pp. 977-984, 2022.
Eid, K., Q. Lu, S. sayed abdel-Azeim, A. Soliman, A. M. Abdullah, A. M. Abdelgwad, R. P. Forbes, K. I. Ozoemena, R. S. Varma, and M. Shibl, "Highly Exfoliated Ti3C2Tx MXene Nanosheets Atomically Doped with Cu for Efficient Electrochemical CO2 Reduction: An Experimental and Theoretical Study", Journal of Materials Chemistry A, vol. 10: Royal Society of Chemistry, pp. 1965-1975, 2022. Abstract

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Gamal, Y., B. M. Younis, S. F. Hegazy, Y. Badr, M. F. O. Hameed, and S. S. A. Obayya, "Highly Sensitive Multi-Functional Plasmonic Biosensor Based on Dual Core Photonic Crystal Fiber", IEEE Sensors Journal, vol. 22, no. 7: IEEE, pp. 6731–6738, 2022. Abstract
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Gamal, Y., B. M. Younis, S. F. Hegazy, Y. Badr, M. F. O. Hameed, and S. S. A. Obayya, "Highly Sensitive Multi-Functional Plasmonic Biosensor Based on Dual Core Photonic Crystal Fiber", IEEE Sensors Journal, vol. 22, no. 7: IEEE, pp. 6731–6738, 2022. Abstract
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Steiner, N., R. F. Turki, W. El-Khayat, G. A. Malki, S. Tannus, and M. H. Dahan, "Histopathological profile of women who had previously failed in-vitro fertilization and the association to the outcome in the subsequent in-vitro fertilization cycle.", Obstetrics & gynecology science, vol. 65, issue 1, pp. 64-73, 2022. Abstract

OBJECTIVE: To evaluate the endometrial histopathological profile of patients undergoing curettage and the association of the histopathological profile with the pregnancy outcome during the subsequent in-vitro fertilization (IVF) cycle.

METHODS: In this retrospective cohort study, a total of 248 women with at least one failed attempt of IVF and who underwent curettage and a subsequent IVF were included. Demographic data, endometrial histopathological records, stimulation information, and pregnancy outcomes were collected and analyzed.

RESULTS: The histopathological analysis of endometrial tissues showed that 130 women (52.4%) had endometrial pathologies. Of these women, 103 (41.5%) had endometrial polyps, 22 (8.9%) had chronic endometritis, and five (2.0%) had both polyps and endometritis. No statistical difference was observed between the normal histopathology group and the abnormal histopathology group in the outcome of the subsequent IVF cycle. Subgroup analyses were performed to further characterize and compare women with normal histopathology and women with endometrial polyps (polyp subgroup) or chronic endometritis (endometritis subgroup). No statistical differences were found among the three groups in the rates of pregnancy (44.1% vs. 49.5% vs. 45.5%, P=0.72), biochemical pregnancy loss (13.5% vs. 15.7% vs. 20.0%, P=0.86), clinical pregnancy loss (25.0% vs. 31.4% vs. 30.0%, P=0.77), and live birth (27.1% vs. 26.2% vs. 22.7%, P=0.91) during the subsequent IVF cycle.

CONCLUSION: Women with previously failed IVF and abnormal endometrial histopathology treated with curettage had the same outcome in the subsequent IVF cycle as women with normal endometrial histopathology.

Sadek, S. A., A. E. Farouk, S. R. Fahmy, and A. M. Soliman, "Holothuria arenicola Extract Attenuated Hepatic Steatosis in Splenectomized Rat Fed High Fat Diet", The Natural Products Journal , vol. 12, issue 3, pp. 87-100, 2022.
Sadek, S. A., A. E. Farouk, S. R. Fahmy, and A. M. Soliman, "Holothuria arenicola Extract Attenuated Hepatic Steatosis in Splenectomized Rat Fed High Fat Diet", The Natural products Journal, vol. 12, issue 3, pp. 87-100, 2022.
Hamed, H., A. M. Helmy, and A. Mohammed, "Holy Quran-Italian seq2seq Machine Translation with Attention Mechanism", 2022 2nd International Mobile, Intelligent, and Ubiquitous Computing Conference (MIUCC), pp. 11-20, 2022. Abstract
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Olawale, F., O. Iwaloye, K. Olofinsan, O. M. Ogunyemi, G. A. Gyebi, and I. M. Ibrahim, "Homology modelling, vHTS, pharmacophore, molecular docking and molecular dynamics studies for the identification of natural compound-derived inhibitor of MRP3 in acute leukaemia treatment", Chemical Papers: Springer, pp. 1–29, 2022. Abstract
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Mohammed, Nader, S.M., Hamza, and M. A. Sabry, "Horse: a potential source of Cryptococcus neoformans and Cryptococcus gattii in Egypt", BMC Veterinary Research , vol. 18, issue 1, pp. 17, 2022.
Medhat, E., G. Ayeldeen, H. H. Ahmed, O. Shaker, T. Gheita, and S. S. Ashour, "HOTAIR and THRIL Long Non Coding RNAs and Their Target Genes in Rheumatoid Arthritis patients.", Reports of biochemistry & molecular biology, vol. 10, issue 4, pp. 614-621, 2022. Abstract

Background: Rheumatoid arthtritis (RA) is a chronic systemic inflammatory autoimmune disease characterized by irreversible joint damage and deformity. The aim of this study is to investigate THRIL and HOTAIR serum expression and their target genes in Egyptian RA patients and to evaluate their relationship to the clinico-pathological data.

Methods: The present study included fifty-two RA patients and fifty-six healthy controls. RA patients were classified according to DAS28 score. All subjects were subjected to full history taking and clinical examination. Quantitative real time PCR was done to estimate the expression levels of serum THRIL and HOTAIR as well as their target genes tumor necrosis factor alpha (TNF-α) and metalloproteinase 2 (MMP-2) were estimated by ELISA techniques.

Results: Results revealed that both THRIL and HOTAIR were statistically over expressed in RA patients compared to healthy group with p-value< 0.05. Results showed as well that the target genes for those long-non coding RNAs, TNF-α and MMP-2, were also significantly higher in RA patients compared to healthy controls.

Conclusion: Both THRIL and HOTAIR associated with their target genes, can be considered as diagnostic markers for RA.

Mongy, N. E. N., and R. F. Hilal, "How far is vitamin D implicated in cutaneous infections", Clinics in Dermatology, 2022.
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