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2021
Mogbel, M. A. S., M. T. Elabbasy, R. S. Mohamed, A. E. Ghoniem, M. F. H. Abd El-kader, and A. A. Menazea, "Improvement in antibacterial activity of Poly Vinyl Pyrrolidone/Chitosan incorporated by graphene oxide NPs via laser ablation", Journal of Polymer Research, vol. 28, issue 12, pp. 1-8, 2021.
Aziz, A. N. Y., S. Mogawer, U. M. A. Garhi, M. A. Ansary, M. Rakha, and H. el shemy, "IMPROVEMENT IN FATIGUE STATUS IN PATIENTS WITH LIVER CIRRHOSIS DUE TO CHRONIC VIRAL HEPATITIS C AFTER VITAMIN D SUPPLEMENTATION", Acta Medica Mediterranea , 2021.
Mogahed, E. A., H. El-Karaksy, H. Abdullatif, N. A. Yasin, A. Nagy, S. A. Alem, H. G. E. deen, and M. S. El-Raziky, "IMPROVEMENT IN LIVER STIFFNESS IN PEDIATRIC HCV PATIENTS AFTER TREATMENT WITH DIRECT ACTING ANTIVIRALS.", The Journal of pediatrics, 2021. Abstract

OBJECTIVES: To assess the degree of liver stiffness using transient elastography (TE) in hepatitis C virus (HCV) infected Egyptian children at baseline and one-year after achievement of sustained virologic response (SVR) with direct acting antivirals (DAAs).

STUDY DESIGN: This prospective study included HCV infected children who received treatment with sofosbuvir/ledipasvir and achieved SVR. At baseline and one-year after achievement of SVR, the extent of hepatic fibrosis was assessed by TE using FibroScan to measure liver stiffness, in addition to non-invasive markers including aspartate aminotransferase (AST)/platelet ratio index (APRI) and Fibrosis-4 (FIB-4) index.

RESULTS: The study included 23 cases that had variable degrees of fibrosis at baseline; their ages ranged between 10-18 years. At baseline, 13 patients had F1, 3 patients had F1-F2, 1 patient had F2, 3 patients had F3, 2 had F3-F4 and 2 patients with F4. One-year after achievement of SVR, there was a statistically significant improvement in liver stiffness, APRI and FIB-4 index (P = .03, <0.001, 0.02 respectively). In 13 patients (56.5%), the liver stiffness improved, in 7 patients it was stationary, and the remaining 3 patients showed mild increase in liver stiffness that was, however, associated with improvement in APRI and FIB-4 index. Co-morbid conditions and previous treatment with interferon were not associated with increased liver stiffness one-year after SVR.

CONCLUSIONS: Egyptian children infected with HCV GT4 achieved significant regression in liver stiffness after treatment with DAAs.

Mogahed, E. A., H. El-Karaksy, H. Abdullatif, N. A. Yasin, A. Nagy, S. A. Alem, H. G. E. deen, and M. S. El-Raziky, Improvement in Liver Stiffness in Pediatric Patients with Hepatitis C Virus after Treatment with Direct Acting Antivirals, , Egypt, 2021. 1-s2.0-s0022347621001219.pdf
Mogahed, E. A., H. El-Karaksy, H. Abdullatif, N. Yasin, A. Nagy, S. A. Alem, H. G. E. deen, and M. S. El-Raziky, "Improvement in Liver Stiffness in Pediatric Patients with Hepatitis C Virus after Treatment with Direct Acting Antivirals", The Journal of Pediatrics, 2021.
Soliman, Z., M. El Kassas, A. Elsharkawy, M. Elbadry, Y. Hamada, R. ElHusseiny, S. M. El-Nahaas, R. Fouad, G. Esmat, and S. A. Alem, Improvement of platelet in thrombocytopenic HCV patients after treatment with direct-acting antiviral agents and its relation to outcome, , Egypt, 2021. platelets.pdf
Soliman, Z., M. El Kassas, A. Elsharkawy, M. Elbadry, Y. Hamada, R. ElHusseiny, S. M. El-Nahaas, R. Fouad, G. Esmat, and S. A. Alem, "Improvement of platelet in thrombocytopenic HCV patients after treatment with direct-acting antiviral agents and its relation to outcome.", Platelets, vol. 32, issue 3, pp. 383-390, 2021. Abstract

Little is known about evolution of platelet count after treatment with direct-acting antiviral agents (DAAs). The study aimed to evaluate the changes in platelet count after treatment with DAAs among thrombocytopenic patients with HCV-related advanced fibrosis and cirrhosis. A total of 915 chronic HCV patients with advanced fibrosis and cirrhosis who were treated with different DAAs-based regimens were retrospectively enrolled in final analysis. Included patients were those with thrombocytopenia (TCP). Platelet count was recorded at baseline, end of treatment (EOT) and 24-weeks after EOT (SVR24). Changes in platelet count and its relation to SVR were analyzed. The overall SVR24 rate was 98.8%. The platelet count showed statistically significant improvement from baseline to EOT (107 (84-127) × 10/mm vs. 120 (87-153) × 10/mm( = <0.0001) but remained unchanged thereafter to SVR24. Among responders, the platelet count significantly increased at SVR24 compared to baseline (<0.0001) but in relapsers, there was improvement in platelet count that didn't reach statistical significance (0.9). Logistic regression analysis showed that higher Child-Pugh score and more advanced fibrosis at baseline were significant predictors of decreasing of platelet count and development of severe TCP at SVR24. Among thrombocytopenic patients with HCV-related advanced fibrosis and cirrhosis, the platelet count improved after treatment with DAAs regardless to treatment response.

Eldessoky, D. S.;, R. M.; Ismail, N. I.; Elarabi, A. A.; Abdelhadi, and N. A. Abdallah, "Improvement of sugarcane for borer resistance using Agrobacterium mediated transformation of cry1Ac gene", GM Crops & Food, 12 (1): 47-56., 2021.
Dessoky, E. S., I. R.M., E. N.I., A. A.A., and N. Abdallah, "Improvement of sugarcane for borer resistance using Agrobacterium mediated transformation of cry1Ac gene", GM Crops & Food, vol. 12, issue 1, pp. 47-56 , 2021.
El-Dessoky E.S., I. R.M., Elarabi Nagwa I., A. A. A., and A. and N.A, "Improvement of sugarcane for borer resistance using Agrobacterium mediated transformation of cry1Ac gene", GM Crops & Food-Biotechnology in Agriculture and the Food Chain, vol. 12 , issue 1, pp. 47–56, 2021.
Farouk, R., E. A. El-Kharadly, A. H. M. Elwahy, H. I. Ibrahim, and A. A. Mousa, "Improvement of the UV-protective Properties of Cotton Fabric Dyed with Polyfunctional Reactive Dye Modified from Reactive Red.", Journal of Textile & Apparel Technology & Management (JTATM), vol. 12, issue 1, 2021. Abstract
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Hammad, K. S. M., N. F. S. Morsy, and E. A. AbdEl-Salam, "Improving oxidative stability of breadstick with ginkgo (Ginkgo biloba) and ginseng (Panax ginseng) dried extracts.", Grasas y Aceites, , vol. 72, issue 3, pp. e424, 2021. breadsticks.pdf
Mabrouk, A. A., M. I. Tadros, and W. M. El-Refaie, "Improving the efficacy of Cyclooxegenase-2 inhibitors in the management of oral cancer: Insights into the implementation of nanotechnology and mucoadhesion", Journal of Drug Delivery Science and Technology, vol. 61, pp. 102240, 2021.
Hammad, K. S. M., N. F. S. Morsy, and A. E. A. El-Salam, "Improving the oxidative stability of breadsticks with ginkgo (Ginkgo biloba) and ginseng (Panax ginseng) dried extracts", GRASAS Y ACEITES, vol. 72, issue 3, pp. e424, 2021. final_breadstick.pdf
Alkhouly, A. A., A. Mohammed, and H. A. Hefny, "Improving the Performance of Deep Neural Networks Using Two Proposed Activation Functions", IEEE Access, vol. 9, pp. 82249-82271, 2021. Abstract
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Ghannam, M., B. Awad, M. S. AlAyed, and others, "Improving the Physical Properties of Polyvinyl Alcohol (PVA)-Melanin Doping", Egyptian Journal of Chemistry, vol. 64, no. 7: National Information and Documentation Centre (NIDOC), Academy of Scientific …, pp. 9–10, 2021. Abstract
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Ghannam, M. G. M., B. Awad, M. S. Al-Ayed, and A. A. Aly, "Improving the Physical Properties of Polyvinyl Alcohol (PVA)-Melanin Doping", Egyptian Journal of Chemistry , vol. 64, issue 7, pp. 3665-3670, 2021.
Benc, M., F. Strejcek, M. Morovic, A. Bartkova, M. Murin, A. Gad, A. Bonnet-Garnier, F. P. Percinic, and J. Laurincik, "Improving the Quality of Oocytes with the Help of Nucleolotransfer Therapy", Pharmaceuticals, vol. 14, no. 4, 2021. AbstractWebsite

The nucleolus is an important nucleus sub-organelle found in almost all eukaryotic cells. On the one hand, it is known as a differentiated active site of ribosome biogenesis in somatic cells, but on the other hand, in fully grown oocytes, zygotes, and early embryos (up to the major embryonic genome activation), it is in the form of a particular homogenous and compact structure called a fibrillar sphere. Nowadays, thanks to recent studies, we know many important functions of this, no doubt, interesting membraneless nucleus sub-organelle involved in oocyte maturation, embryonic genome activation, rRNA synthesis, etc. However, many questions are still unexplained and remain a mystery. Our aim is to create a comprehensive overview of the recent knowledge on the fibrillar sphere and envision how this knowledge could be utilized in further research in the field of biotechnology and nucleolotransfer therapy.

Ahmed, M. I., A. Elshorbagy, A. Pietroniro, and D. Princz, "Improving the representation of the non-contributing area dynamics in land surface models for better simulation of prairie hydrology", Journal of Hydrology, vol. 600: Elsevier, pp. 126562, 2021. Abstract
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Elghazouli, A. Y., D. V. Bompa, S. A. Mourad, and A. Elyamani, "In plane lateral cyclic behaviour of lime mortar and clay brick masonry walls in dry and wet conditions", Bulletin of Earthquake Engineering, issue Article 1170, 2021.
Ahmed, M. I., and others, In Pursuit of Improving Peak Flow Prediction in the Canadian Prairies, : University of Saskatchewan, 2021. Abstract
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Abdel-Moneim, M. A., "In search of a school façade: Explaining the centrality of private tutoring among high-performing students in Egypt", International Journal of Educational Development, vol. 83, 2021.
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