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1976
El Sherbini, T. M., "Transition probabilities and radiative lifetimes for singly ionized xenon", Journal of Physics B: Atomic and Molecular Physics, vol. 9, issue 10: IOP Publishing, pp. 1665, 1976. Abstract
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Shokry, M., H. M. Morad, and I. A. Khalil, "Untersuchungen uber die Wirkung von Rompun beim Schaf", Veterinar Medizinische Nachrichten, 1976. Abstract
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Gihad, E. A., "Value of dried poultry manure and urea as protein supplements for sheep consuming low quality tropical hay", Journal of Animal Science, vol. 42, issue 3: American Society of Animal Science, pp. 706-709, 1976. Abstract
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El-Hammady, M., H. M. Mazyad, M. A. Tolba, and M. A. Shafie, "Virus diseases of some medicinal plants in Egypt. I. A strain of potato virus X on Egyptian henbane (Hyoscyamus muticus L.)", Ann Agric Sci Moshtohor, 1976. Abstract
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Hafez, M., M. Hilali, and M. Refai, "Vorkommen von Pilzen im Darmtrakt einiger blutsaugender Fliegen in Agypten", Wiener tierarztliche Monatsschrift, 1976. Abstract
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1975
P.hutchinson, E. E.Khalil, J.H.Whitelaw, and G.Wigley, "The Calculation of Furnace Flow Properties and their Experimental Verificatoion", ASME Heat ransfer Conference, ASME PAPER 75-HT-8. , USA, June 1975.
M., K., and M. F. Hassan, "Computerized Techni-ques for Hospital Layout", The 11th Annual Conference for Statistics and Scientific Computations, Cairo 14-17, 1975.
Akamatsu, N., H. Nakajima, M. Ono, and Y. Miura, "Increase in acetyl CoA synthetase activity after phenobarbital treatment.", Biochemical pharmacology, vol. 24, issue 18, pp. 1725-7, 1975 Sep 15. Abstract
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Turner, A. J., and P. E. Hick, "Inhibition of aldehyde reductase by acidic metabolites of the biogenic amines.", Biochemical pharmacology, vol. 24, issue 18, pp. 1731-3, 1975 Sep 15. Abstract
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Bhagwat, V. M., and B. V. Ramachandran, "Malathion A and B esterases of mouse liver-I.", Biochemical pharmacology, vol. 24, issue 18, pp. 1713-7, 1975 Sep 15. Abstract
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Marniemi, J., and M. G. Parkki, "Radiochemical assay of glutathione S-epoxide transferase and its enhancement by phenobarbital in rat liver in vivo.", Biochemical pharmacology, vol. 24, issue 17, pp. 1569-72, 1975 Sep 1. Abstract
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Silen, W., T. E. Machen, and J. G. Forte, "Acid-base balance in amphibian gastric mucosa.", The American journal of physiology, vol. 229, issue 3, pp. 721-30, 1975 Sep. Abstract

It has been established that H+ secretion can be maintained in frog stomach in the absence of exogenous CO2 by using a nutrient bathing fluid containing 25 mM H2PO4 (pH approximately equal to 4.5) or by lowering the pH of a nonbuffered nutrient solution to about 3.0-3.6. Exogenous CO2 in the presence of these nutrient solutions uniformly caused a marked decrease in H+ secretion, PD, adn short-circuit current (Isc) and an increase in transmucosal resistance (R). Elevation of nutrient [k+] to 83 mM reduced R significantly but transiently without change in H+ when nutrient pH less than 5.0, whereas R returned to base line and H+ increased when nutrient pH greater than 5.0. Acidification of the nutrient medium in the presence of exogenous CO2 results in inhibition of the secretory pump, probably by decreasing intracellular pH, and also interferes with conductance at the nutrient membrane. Removal of exogenous CO2 from standard bicarbonate nutrient solution reduced by 50% the H+, PD, and Isc without change in R; K+-free nutrient solutions reverse these changes in Isc and PD but not in H+. The dropping PD and rising R induced by K+-free nutrient solutions in 5% CO2 - 95% O2 are returned toward normal by 100% O2. Our findings support an important role for exogenous CO2 in maintaining normal acid-base balance in frog mucosa by acting as an acidifying agent.

Silen, W., T. E. Machen, and J. G. Forte, "Acid-base balance in amphibian gastric mucosa.", The American journal of physiology, vol. 229, issue 3, pp. 721-30, 1975 Sep. Abstract

It has been established that H+ secretion can be maintained in frog stomach in the absence of exogenous CO2 by using a nutrient bathing fluid containing 25 mM H2PO4 (pH approximately equal to 4.5) or by lowering the pH of a nonbuffered nutrient solution to about 3.0-3.6. Exogenous CO2 in the presence of these nutrient solutions uniformly caused a marked decrease in H+ secretion, PD, adn short-circuit current (Isc) and an increase in transmucosal resistance (R). Elevation of nutrient [k+] to 83 mM reduced R significantly but transiently without change in H+ when nutrient pH less than 5.0, whereas R returned to base line and H+ increased when nutrient pH greater than 5.0. Acidification of the nutrient medium in the presence of exogenous CO2 results in inhibition of the secretory pump, probably by decreasing intracellular pH, and also interferes with conductance at the nutrient membrane. Removal of exogenous CO2 from standard bicarbonate nutrient solution reduced by 50% the H+, PD, and Isc without change in R; K+-free nutrient solutions reverse these changes in Isc and PD but not in H+. The dropping PD and rising R induced by K+-free nutrient solutions in 5% CO2 - 95% O2 are returned toward normal by 100% O2. Our findings support an important role for exogenous CO2 in maintaining normal acid-base balance in frog mucosa by acting as an acidifying agent.

Poole-Wilson, P. A., and G. A. Langer, "Effect of pH on ionic exchange and function in rat and rabbit myocardium.", The American journal of physiology, vol. 229, issue 3, pp. 570-81, 1975 Sep. Abstract

The effects of pH variation on ionic exchange and mechanical function were studied in the arterially perfused rat and rabbit septa. The pH and PCO2 of the control perfusate were 7.40 and 39 mmHg, respectively. In the rabbit septum a metabolic acidosis (pH equals 6.82, PCO2 equals 39 mmHg) caused a loss of 16% of control tension in 12 min. Na+ and K+ exchange were unaltered. A comparable respiratory acidosis (pH equals 6.81, PCO2 equals 159 mmHg) caused a 51% loss of tension in 2 min. Na+ exchange was unaltered but K+ efflux fell from 8.9 +/- 0.6 (mean +/- SE) to 4.9 +/- 0.3 mmol/kg dry wt per min (P less than 0.001, n equals 10). A net gain of K+ of 16.9 +/- 1.7 (n equals 14) mmol/kg dry wt occurred and was attributable to a delayed fall in K+ influx relative to efflux over 15 min. The net gain could not be mimicked by epinephrine administration or blocked by propranolol and was absent in the beating rat septum and the quiescent rabbit septum. These results suggest that the net uptake of K+, which appears to be dependent on a period of depolarization, and the changes of contractility are controlled by the H+ ion concentration at a cellular site whose exchange with the extracellular space is characterized by a considerable restriction of diffusion. Changes of contractility are not related to the net uptake of K+.

Poole-Wilson, P. A., and G. A. Langer, "Effect of pH on ionic exchange and function in rat and rabbit myocardium.", The American journal of physiology, vol. 229, issue 3, pp. 570-81, 1975 Sep. Abstract

The effects of pH variation on ionic exchange and mechanical function were studied in the arterially perfused rat and rabbit septa. The pH and PCO2 of the control perfusate were 7.40 and 39 mmHg, respectively. In the rabbit septum a metabolic acidosis (pH equals 6.82, PCO2 equals 39 mmHg) caused a loss of 16% of control tension in 12 min. Na+ and K+ exchange were unaltered. A comparable respiratory acidosis (pH equals 6.81, PCO2 equals 159 mmHg) caused a 51% loss of tension in 2 min. Na+ exchange was unaltered but K+ efflux fell from 8.9 +/- 0.6 (mean +/- SE) to 4.9 +/- 0.3 mmol/kg dry wt per min (P less than 0.001, n equals 10). A net gain of K+ of 16.9 +/- 1.7 (n equals 14) mmol/kg dry wt occurred and was attributable to a delayed fall in K+ influx relative to efflux over 15 min. The net gain could not be mimicked by epinephrine administration or blocked by propranolol and was absent in the beating rat septum and the quiescent rabbit septum. These results suggest that the net uptake of K+, which appears to be dependent on a period of depolarization, and the changes of contractility are controlled by the H+ ion concentration at a cellular site whose exchange with the extracellular space is characterized by a considerable restriction of diffusion. Changes of contractility are not related to the net uptake of K+.

Coscia, L., P. Causa, E. Giuliani, and A. Nunziata, "Pharmacological properties of new neuroleptic compounds.", Arzneimittel-Forschung, vol. 25, issue 9, pp. 1436-42, 1975 Sep. Abstract

RMI 61 140, RMI 61 144 and RMI 61 280 are newly synthetized N-[8-R-dibenzo(b,f)oxepin-10-yl]-N'-methyl-piperazine-maleates which show interesting psychopharmacologic effects. This work contains the results of a study performed with these three compounds, in order to demonstrate their neuropsycholeptic activity in comparison with chloropromazine (CPZ) and chlordiazepoxide (CPD). The inhibition of motility observed in mice shows that the compounds reduce the normal spontaneous motility as well as the muscle tone. The central-depressant activity is evidenced by increased barbiturate-induced sleep and a remarkable eyelid ptosis can also be observed. Our compounds do not show any activity on electroshock just as do CPZ and CPD. As to the antipsychotic outline, our compounds show strong reduction of lethality due to amphetamine in grouped mice and a strong antiapomorphine activity. They show also an antiaggressive effect and an inhibitory activity on avoidance behaviour much stronger than CPZ. We have also found extrapyramidal effects, as catalepsy, common to many tranquillizers of the kind of the standards used by us. As for vegetative phenomena, the compounds show hypotensive dose related action ranging from moderate to strong, probably due to an a-receptor inhibition. Adrenolytic activity against lethal doses of adrenaline, antiserotonin and antihistaminic effects, as well as other actions (hypothermia, analgesia, etc.) confirm that RMI 61 140, RMI 61 144 and RMI 61 280 are endowed with pharmacologic properties similar and more potent than those of CPZ. Studies on the metabolism of brain catecholamines show that they are similar to CPZ, although with less effect on dopamine level.

Coscia, L., P. Causa, E. Giuliani, and A. Nunziata, "Pharmacological properties of new neuroleptic compounds.", Arzneimittel-Forschung, vol. 25, issue 9, pp. 1436-42, 1975 Sep. Abstract

RMI 61 140, RMI 61 144 and RMI 61 280 are newly synthetized N-[8-R-dibenzo(b,f)oxepin-10-yl]-N'-methyl-piperazine-maleates which show interesting psychopharmacologic effects. This work contains the results of a study performed with these three compounds, in order to demonstrate their neuropsycholeptic activity in comparison with chloropromazine (CPZ) and chlordiazepoxide (CPD). The inhibition of motility observed in mice shows that the compounds reduce the normal spontaneous motility as well as the muscle tone. The central-depressant activity is evidenced by increased barbiturate-induced sleep and a remarkable eyelid ptosis can also be observed. Our compounds do not show any activity on electroshock just as do CPZ and CPD. As to the antipsychotic outline, our compounds show strong reduction of lethality due to amphetamine in grouped mice and a strong antiapomorphine activity. They show also an antiaggressive effect and an inhibitory activity on avoidance behaviour much stronger than CPZ. We have also found extrapyramidal effects, as catalepsy, common to many tranquillizers of the kind of the standards used by us. As for vegetative phenomena, the compounds show hypotensive dose related action ranging from moderate to strong, probably due to an a-receptor inhibition. Adrenolytic activity against lethal doses of adrenaline, antiserotonin and antihistaminic effects, as well as other actions (hypothermia, analgesia, etc.) confirm that RMI 61 140, RMI 61 144 and RMI 61 280 are endowed with pharmacologic properties similar and more potent than those of CPZ. Studies on the metabolism of brain catecholamines show that they are similar to CPZ, although with less effect on dopamine level.

Hendrickson, W. A., and K. B. Ward, "Atomic models for the polypeptide backbones of myohemerythrin and hemerythrin.", Biochemical and biophysical research communications, vol. 66, issue 4, pp. 1349-56, 1975 Oct 27. Abstract
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Wiesmann, U. N., S. DiDonato, and N. N. Herschkowitz, "Effect of chloroquine on cultured fibroblasts: release of lysosomal hydrolases and inhibition of their uptake.", Biochemical and biophysical research communications, vol. 66, issue 4, pp. 1338-43, 1975 Oct 27. Abstract
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Smith, R. J., and R. G. Bryant, "Metal substitutions incarbonic anhydrase: a halide ion probe study.", Biochemical and biophysical research communications, vol. 66, issue 4, pp. 1281-6, 1975 Oct 27. Abstract
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Chow, Y. W., R. Pietranico, and A. Mukerji, "Studies of oxygen binding energy to hemoglobin molecule.", Biochemical and biophysical research communications, vol. 66, issue 4, pp. 1424-31, 1975 Oct 27. Abstract
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Crow, T. J., J. F. Deakin, and A. Longden, "Proceedings: Do anti-psychotic drugs act by dopamine receptor blockade in the nucleus accumbens.", British journal of pharmacology, vol. 55, issue 2, pp. 295P-296P, 1975 Oct. Abstract
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