Publications

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2021
F. M. Abdelrazek, S. M. Gomha, M. S. Farghaly, and P. Metz, "One-Pot, three-component synthesis of pyrido[2,3-d]pyrimidinones using aluminate sulfonic acid nanocatalyst under grinding technique.", Polycyclic Aromatic Compounds, vol. 41, issue 7, pp. 1472-1482, 2021.
L. A. Al-Mutabagani, F. M. Abdelrazek, S. M. Gomha, A. S. Hebishy, M. S. Abdelfattah, S. M. Hassan, and M. M. Elaaser, "Synthesis and biological evaluation of thiazolyl-ethylidene hydrazino-thiazole derivatives: A novel heterocyclic system.", Applied Sciences , vol. 11, issue 19, pp. 8908-8920, 2021.
2020
Mansour, E., Ekhlas M. Nassar, Ahmed. F. El-Farargy, and F. M. Abdelrazek, "An eco-friendly synthesis of some novel chromene-based heterocyclic compounds of biological interest.", Russ. J. BioOrg. Chem., vol. 46, issue 4, pp. 582-589, 2020.
Abdelrazek, F. M., S. M. Gomha, H. M. Abdel-Aziz, M. S. Farghaly, P. Metz, and A. Abdel-Shafy, "Efficient Synthesis and In-Silico Study of Some Novel Pyrido[2,3-d][1,2,4]Triazolo[4,3-a]Pyrimidine Derivatives", J. Heterocyclic Chem., vol. 57, issue 4, pp. 1759-1769, 2020. farghaly_phdiii_jhc2020.pdf
Nadia H. Metwally, Fathy M. Abdelrazek, and S. M. Eldaly, "Synthesis, reactions and antimicrobial activity of 2-cyano-N`-(4-(2-oxo-2-phenylethoxy)benzylidene)acetohydrazide derivatives.", J. Heterocyclic Chem., vol. 57, issue 10, pp. 3653-3663, 2020. jhc_nadia_salwa_october_2020.pdf
2019
Fathy M. Abdelrazek, S. M.Gomha, Mohamed E. B. Shaaban, Kamal A. Rabee, Heba N. El-Shemy, Abanoub M. Abdallah, and P. Metz, "One-Pot Three-Component Synthesis and Molecular Docking of Some Novel 2-Thiazolyl Pyridines as Potent Antimicrobial Agents", Mini-Reviews in Medicinal Chemistry, vol. 19, issue 6, pp. 527-538, 2019. Abstractmini_reviews.doc

A novel series of 2-thiazolyl pyridines was prepared in a one-pot three-component reaction using 2-bromoacetyl pyridine as a starting precursor. The structure of all products was established on the bases of spectral data and elemental analyses and alternative synthesis if possible. The prepared compounds were screened for their in vitro antimicrobial activity and some derivatives showed promising activity. Molecular docking studies were carried out for the two synthesized compounds (4a and 4b) which exhibited the best activities against most of the tested microorganisms by using default parameters with MOE software. There was an agreement between the values of binding affinities and interactions and the data obtained from the practical antimicrobial screening of the tested compounds.

Khlood S. Abdel Zaher, Salwa H. El-Sabbagh, Fathy M. Abdelrazek, and G. A. M. Nawwar, "Utility of Zinc (Lignin/Silica/Fatty Acids) Complex Driven From Rice Straw as Antioxidant and Activator in Rubber Composites", Polymer Engineering & Science, vol. 59, issue s2, pp. E196-E205, 2019. khlood_paper_pdf.pdf
Sayed, A. R., S. M. Gomha, F. M. Abdelrazek, M. S. Farghaly, S. A Hassan, and P. Metz, "Design, efficient synthesis and molecular docking of some novel thiazolyl-pyrazole derivatives as anticancer agents", BMC Chemistry, vol. 13, issue 116, pp. 1-13, 2019.
Fathy M. Abdelrazek, S. M.Gomha, Mohamed S. Farghaly, and P. Metz, "One-Pot, Three-Component Synthesis of Pyrido[2,3-d]pyrimidinones Using Aluminate Sulfonic Acid Nanocatalyst Under Grinding Technique", Polycyclic Aromatic Compounds, vol. 11, issue 11, pp. 1-11, 2019.
Abdelrazek, F. M., P. Metz, and A. Jaeger, "Some Reactions With Indane-1,3-dione: A Facile Synthesis of Pentacycline Heterocyclic Analogues", J. Heterocyclic Chem., vol. 56, issue 7, pp. 1939-1945, 2019. ind-dione_paper.pdf
2018
Abdelrazek, F. M., S. M. Gomha, M. E. B. Shaaban, A. I. Lotfi, and H. N. El-Shemy, "Facile synthesis of some novel triazolo[3,4- b]thiadiazines and triazolo[4,3-b]tetrazines", Synthetic Communications, vol. 48, issue 1, pp. 32-37, 2018. facile_synthesis_of_some_novel_triazolo_3_4_b_thiadiazines_and_triazolo_4_3_b_tetrazines.pdf
Nassar, I. F., E. A. F. Farargy, and F. M. Abdelrazek, "Synthesis and anti-cancer activity of some new fused pyrazoles and their glycoside derivatives.", J. Heterocyclic Chem., vol. 55, issue 7, pp. 1709-1719, 2018.
Gomha, S. M., F. M. Abdelrazek, A. H. Abdelrahman, and P. Metz, "Synthesis of some new pyridine-based heterocyclic compounds with anticipated anti-tumor activity.", J. Heterocyclic Chem., vol. 55, issue 7, pp. 1729-1737, 2018. jhc_alyiii__2-18.pdf
2017
Metwally, N. H., F. M. Abdelrazek, S. M. Eldaly, and P. Metz, "3-(3,5-Dimethyl-1H-Pyrazol-1-yl)-3-Oxopropanenitrile as Precursor for Some New Mono-Heterocyclic and Bis-Heterocyclic Compounds", J. Heterocyclic Chem., vol. 54, issue 1, pp. 289-294, 2017. metwally_et_al-2017-journal_of_heterocyclic_chemistry.pdf
Ibrahim F. Nassar, Ahmed F. El Farargy, Fathy M. Abdelrazek, and N. S. M. Ismail, "Design, synthesis and anticancer evaluation of novel pyrazole, pyrazolo[3,4-d]pyrimidine and their glycoside derivatives", Nucleosides, Nucleotides and Nucleic Acids, vol. 36, issue 4, pp. 275-291, 2017.
Abdelrazek, F. M., P. Metz, A. Jäger, and N. H. Metwally, "An Eco-friendly Synthesis of Some Novel 4-methyl-4-hetaryl Chromene and Pyrano[2,3-c]pyrazole Derivatives", J. Heterocyclic Chem., vol. 54, issue 4, pp. 2313-2318, 2017. abdelrazek_et_al-2017-journal_of_heterocyclic_chemistry.pdf
Abdelrazek, F. M., S. M. Gomha, A. H. Abdelrahman, P. Metz, and M. A. Sayed, "A Facile Synthesis and Drug Design of Some New Heterocyclic Compounds Incorporating Pyridine Moiety and Their Antimicrobial Evaluation", Letters in Drug Design & Discovery, vol. 14, issue 6, pp. 752-762, 2017.
Abdelrazek, F. M., S. M. Gomha, P. Metz, and M. M. Abdalla, "Synthesis of Some Novel 1,4-Phenylene-bis-thiazolyl Derivatives and Their Anti-hypertensive α-blocking Activity Screening", J. Heterocyclic Chem., vol. 54, issue 1, pp. 618-623, 2017. abdelrazek_et_al-2017-journal_of_heterocyclic_chemistry.pdf
2016
Gomha, S. M., and F. M. Abdelrazek, "A Facile Three-Component One-Pot Synthesis of Some Novel Tricyclic Hetero-Ring Systems", J. Heterocyclic Chem., vol. 53, issue 6, pp. 1892-1896, 2016. jhet_sobhi_me.pdf
Metwally, N. H., F. M. Abdelrazek, and S. M. El-Daly, "Synthesis and anticancer activity of some new heterocyclic compounds based on 1-cyanoacetyl-3, 5-dimethylpyrazole", Research on Chemical Intermediates, vol. 42, issue 2, pp. 1071-1089, 2016. salwa_i_res_chem_intermed.pdf
Nassar, E. M., F. M. Abdelrazek, R. R. Ayyad, and A. F. El-Farargy, "Synthesis and Some Reactions of 1-aryl-4-acetyl-5-methyl-1,2,3-triazole Derivatives with Anticonvulsant Activity", Mini Reviews in Medicinal Chemistry, vol. 16, issue 11, pp. 926-936, 2016. mini_review_2016_ekhlass-farargy.pdf
Gomha, S. M., F. M. Abdelrazek, A. H. Abdelrahman, and P. Metz, "SYNTHESIS OF SOME NOVEL THIAZOLE, THIADIAZOLE AND 1,4- PHENYLENE-BIS-THIAZOLE DERIVATIVES AS POTENT ANTITUMOR AGENTS", Heterocycles (Jpn), vol. 92, issue 5, pp. 954-967, 2016. heterocycles.pdf
2015
Abdelrazek, F. M., M. H. Hilal, A. M. Salah, and S. M. Hassan, "A novel synthesis of some 1,4-phenylene-bis-heterocyclic derivatives and of some pyran, pyrano-[2,3-c]pyrazole and pyrano[2,3-d]pyrimidine derivatives.", J. Heterocyclic Chem., vol. 52, issue 4, pp. 1026-1030, 2015.
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