Publications

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2022
Hassan, M. S. A., E. M. Ahmed, A. A. El‐Malah, and A. S. M. A. A. E. KASSAB, "Anti‐inflammatory activity of pyridazinones: A review", Arch. Pharm., vol. 355, pp. e2200067, 2022.
Abdelhaleem, E. F., A. S. M. A. A. E. KASSAB, H. B. El-Nassan, and O. M. Khalil, "Design and Synthesis of Novel Celecoxib Analogues with Potential Cytotoxic and Pro-apoptotic Activity against Breast Cancer Cell Line MCF-7", Medicinal Chemistry, vol. 18, pp. 903-914, 2022.
Swedan, H. K., A. S. M. A. A. E. KASSAB, E. M. Gedawy, and S. E. Elmeligie, "Design, synthesis, and biological evaluation of novel ciprofloxacin derivatives as potential anticancer agents targeting topoisomerase II enzyme", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 38, issue 1, pp. 118–137, 2022.
Eissa, K. I., M. M. Kamel, L. W. Mohamed, M. A. Galal, and A. S. M. A. A. E. KASSAB, "Design, synthesis, and biological evaluation of thienopyrimidine and thienotriazine derivatives as multitarget anti‐Alzheimer agents", Drug Development Research, vol. 83, pp. 1394–1407, 2022.
Maher, M., A. S. H. R. A. F. F. ZAHER, Z. Mahmoud, and A. S. M. A. A. E. KASSAB, "Recent green approaches for the synthesis of pyrazolo[3,4‐d]pyrimidines: A mini review", Arch. Pharm., vol. 355, pp. e2100470, 2022.
2021
KASSAB, A. S. M. A. A. E., E. M. Gedawy, M. I. A. Hamed, and A. S. D. & R. A. Hassan, "Design, synthesis, anticancer evaluation and molecular modeling studies of novel tolmetin derivatives as potential VEGFR-2 inhibitors and apoptosis inducers", Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 36, issue 1, pp. 922-939, 2021.
2020
Gedawy, E. M., A. S. M. A. A. E. KASSAB, and A. E. M. Kerdawy, "Design, synthesis and biological evaluation of novel pyrazole sulfonamide derivatives as dual COX-2/5-LOX inhibitors", European Journal of Medicinal Chemistry, vol. 189, pp. 112066, 2020.
Inas G. Shahin, K. M. O., A. T. T. Nader S. Abutaleb, M. S. N. Marwa Alhashimi, and A. M. S. ASMAA E. KASSAB, "Evaluation of N-phenyl-2-aminothiazoles for treatment of multi-drug resistant and intracellular Staphylococcus aureus infections", European Journal of Medicinal Chemistry, vol. 202, pp. 112497, 2020.
Shahin, I. G., N. S. Abutaleb, M. Alhashimi, and A. S. M. A. A. E. KASSAB, "Evaluation of N-phenyl-2-aminothiazoles for treatment of multi-drug resistant and intracellular Staphylococcus aureus infections", European Journal of Medicinal Chemistry, vol. 202, pp. 112497, 2020.
Ahmed, E. M., M. S. A. Hassan, A. A. El-Malah, and A. S. M. A. A. E. KASSAB, "New pyridazine derivatives as selective COX-2 inhibitors and potential antiinflammatory agents; design, synthesis and biological evaluation", Bioorganic Chemistry, vol. 95, pp. 103497, 2020.
KASSAB, A. S. M. A. A. E., Y. El‐Dash, and E. M. Gedawy, "Novel pyrazolopyrimidine urea derivatives: Synthesis, antiproliferative activity, VEGFR‐2 inhibition, and effects on the cell cycle profile", Arch der Pharmazie, vol. 353, issue 4, pp. 1900319, 2020.
2019
Maher, M., A. S. M. A. A. E. KASSAB, A. S. H. R. A. F. F. ZAHER, and Z. Mahmoud, "Novel pyrazolo[3,4-d]pyrimidines: design, synthesis, anticancer activity, dual EGFR/ErbB2 receptor tyrosine kinases inhibitory activity, effects on cell cycle profile and caspase-3-mediated apoptosis", JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol. 34, issue 1, pp. 532–546, 2019.
Maher, M., A. Kassab, A. F. Zaher, and Z. Mahmoud, "Novel pyrazolo[3,4-d]pyrimidines as potential cytotoxic agents: Design, synthesis, molecular docking and CDK2 inhibition", Anti-Cancer Agents in Medicinal Chemistry, vol. 19, pp. 1368-1381, 2019.
Ahmed, E. M., A. S. M. A. A. E. KASSAB, A. A. El-Malah, and M. S. A. Hassan, "Synthesis and biological evaluation of pyridazinone derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents", European Journal of Medicinal Chemistry, vol. 171, pp. 25-37, 2019.
2018
Abdelhaleem, E. F., M. K. Abdelhameid, A. S. M. A. A. E. KASSAB, and M. M. Kandeel, "Design and synthesis of thienopyrimidine urea derivatives with potential cytotoxic and pro-apoptotic activity against breast cancer cell line MCF-7", European Journal of Medicinal Chemistry, vol. 143, pp. 1807-1825, 2018.
El-Bakhshawangy, N. M., H. B. El-Nassan, A. S. M. A. A. E. KASSAB, and A. T. Taher, "Design, synthesis and biological evaluation of chromenopyrimidines as potential cytotoxic agents", FutureMed. Chem. , vol. 10, issue 12, pp. 1465–1481, 2018.
KASSAB, A. S. M. A. A. E., and R. A. Hassan, "Novel benzotriazole N-acylarylhydrazone hybrids: Design, synthesis, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and FAK inhibition", Bioorganic Chemistry, vol. 80, pp. 531–544, 2018.
KASSAB, A. S. M. A. A. E., and E. M. Gedawy, "Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity", European Journal of Medicinal Chemistry, vol. 150, pp. 403-418, 2018.
2017
Kassab, A. E., E. M. Gedawy, and H. B. El-Nassan, Synthesis of 4-Heteroaryl–Quinazoline Derivatives as Potential Anti-breast Cancer Agents, , 2017.
2016
KASSAB, A. S. M. A. A. E., E. M. Gedawy, Z. Mahmoud, and R. A. Khattab, "DESIGN, SYNTHESIS, ANTITUMOR AND ANTIMICROBIAL ACTIVITY OF NOVEL 6,7-DIMETHOXYQUINAZOLINE DERIVATIVES", Heterocycles, vol. 92, issue 2, pp. 272-290, 2016. heterocycles.pdf
Kassab, A. E., E. M. Gedawy, A. A. El-Malah, and T. M. Abdelghany, Synthesis, Anticancer Activity, Effect on Cell Cycle Profile, and Apoptosis-Inducing Ability of Novel Hexahydrocyclooctathieno[2,3-d]pyrimidine Derivatives, , 2016.
2015
El-Malah, A. A., and A. S. M. A. A. E. KASSAB, "Design, Synthesis and Biological Evaluation of New Thieno[2,3-d]pyrimidines as Anti-inflammatory Agents", Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, vol. 14, pp. 204-214, 2015. antiinflammatory_final.pdf
Gedawy, E. M., A. S. M. A. A. E. KASSAB, and A. A. El-Malah, "Synthesis and anticancer activity of novel tetrahydroquinoline and tetrahydropyrimidoquinoline derivatives", MEDICINAL CHEMISTRY RESEARCH, vol. 24, pp. 3387–3397, 2015. pyrimidoquinoline_ehab.pdf
Kandeel, M. M., H. M. Refaat, A. S. M. A. A. E. KASSAB, and I. G. Shahin, "Synthesis, anticancer activity and effects on cell cycle profile and apoptosis of novel thieno[2,3-d]pyrimidine and thieno[3,2-e] triazolo [4,3-c]pyrimidine derivatives", European Journal of Medicinal Chemistry, vol. 90, pp. 620-632, 2015. inas.pdf
2014
El-Malah, A., E. M. Gedawy, A. S. M. A. A. E. KASSAB, and R. A. M. Salam, "Novel Tacrine Analogs as Potential Cholinesterase Inhibitors in Alzheimer’s Disease", Arch. Pharm. Chem. Life Sci, vol. 347, pp. 96–103, 2014. afaf_asmaa_ehab.pdf