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Arafat, M. A. M., M. N. A. Khalil, O. G. Mohamed, O. A. M. Abd El-Ghafar, A. Tripathi, E. A. Mahrous, E. M. Abd El-Kader, and S. El-Hawary, "Vetiver aerial parts and roots ameliorate rheumatoid arthritis in complete Freund's adjuvant rat model, a phytochemical profiling and mechanistic study", Journal of Ethnopharmacology, vol. 317: Elsevier, pp. 116764, 2023. Abstract
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, Unlocking the power of onion peel extracts: antimicrobial and anti-inflammatory effects improve wound healing through repressing notch-1/NLRP3/caspase-1 signaling, , 2023.
Mounir, R., W. A. Alshareef, E. A. El Gebaly, A. E. El-Haddad, A. S. M. Ahmed, O. G. Mohamed, E. T. Enan, S. Mosallam, A. Tripathi, and H. M. R. M. Selim, "Unlocking the power of onion peel extracts: antimicrobial and anti-inflammatory effects improve wound healing through repressing notch-1/NLRP3/caspase-1 signaling", Pharmaceuticals, vol. 16, issue 10: MDPI, pp. 1379, 2023. Abstract
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Shalaby, A. S., H. H. Eid, R. A. El-Shiekh, O. G. Mohamed, A. Tripathi, A. A. Al-karmalawy, A. A. Sleem, F. A. Morsy, K. M. Ibrahim, and S. H. Tadros, "Taming food–drug interaction risk: Potential inhibitory effects of citrus juices on cytochrome liver enzymes can safeguard the liver from overdose paracetamol-induced hepatotoxicity", ACS omega, vol. 8, issue 29: American Chemical Society, pp. 26444-26457, 2023. Abstract
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Yancey, C. E., L. Hart, A. C. Lad, J. A. Birbeck, S. Song, O. G. Mohamed, A. M. Fribley, S. T. Haller, A. Tripathi, and D. J. Kennedy, "Synthesis of a Truncated Microcystin Tetrapeptide Molecule from a Partial Mcy Gene Cluster in Microcystis Cultures and Blooms", Environmental Science & Technology: American Chemical Society, 2024. Abstract
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Mahjour, B., R. Zhang, Y. Shen, A. McGrath, R. Zhao, O. G. Mohamed, Y. Lin, Z. Zhang, J. L. Douthwaite, and A. Tripathi, "Rapid planning and analysis of high-throughput experiment arrays for reaction discovery", Nature Communications, vol. 14, issue 1: Nature Publishing Group UK London, pp. 3924, 2023. Abstract
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Mohamed, O. G., Z. G. Khalil, and R. J. Capon, "Prolinimines: N-Amino-l-Pro-methyl Ester (Hydrazine) Schiff Bases from a Fish Gastrointestinal Tract-Derived Fungus, Trichoderma sp. CMB-F563", organic letters, vol. 20, issue 2, pp. 377-380, 2018.
Mohamed, O. G., Z. G. Khalil, and R. J. Capon, "Prolinimines: N-Amino-L-Pro-methyl ester (hydrazine) Schiff bases from a fish gastrointestinal tract-derived fungus, Trichoderma sp. CMB-F563", Organic letters, vol. 20, issue 2: American Chemical Society, pp. 377-380, 2018. Abstract
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Mohamed, O. G., Z. G. Khalil, and R. J. Capon, "Prolinimines: N-Amino-L-Pro-methyl ester (hydrazine) Schiff bases from a fish gastrointestinal tract-derived fungus, Trichoderma sp. CMB-F563", Organic letters, vol. 20, no. 2: American Chemical Society, pp. 377–380, 2018. Abstract
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Mohamed, O. G., A pharmacognostical study of certain Bambusa species cultivated in Egypt, , 2013.
Mohamed, O. G. M., A pharmacognostical study of certain bambusa species cultivated in Egypt, : Cairo University, 2013. Abstract
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KHALED, D., O. S. A. M. A. MOHAMED, I. Alaa, and A. Adel, "Opioid Free Anesthesia versus Opioid Based Anesthesia for Hemodynamic Stability in Geriatric Patients Undergoing Arthroscopic Shoulder Surgery, A Randomized Comparative Study", Egyptian Journal of Anaesthesia, vol. 39, issue 1: Taylor & Francis, pp. 626-634, 2023. Abstract
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Dirks, A. C., O. G. Mohamed, P. J. Schultz, A. N. Miller, A. Tripathi, and T. Y. James, "Not all bad: Gyromitrin has a limited distribution in the false morels as determined by a new ultra high-performance liquid chromatography method", Mycologia, vol. 115, issue 1: Taylor & Francis, pp. 1-15, 2023. Abstract
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Mohamed, O. G., Z. G. Khalil, and R. J. Capon, "N-Amino-l-Proline Methyl Ester from an Australian Fish Gut-Derived Fungus: Challenging the Distinction between Natural Product and Artifact", Marine Drugs, vol. 19, no. 3, 2021. AbstractWebsite

Further investigation into a fish gut-derived fungus Evlachovaea sp. CMB-F563, previously reported to produce the unprecedented Schiff base prolinimines A–B (1–2), revealed a new cryptic natural product, N-amino-l-proline methyl ester (5)—only the second reported natural occurrence of an N-amino-proline, and the first from a microbial source. To enable these investigations, we developed a highly sensitive analytical derivitization methodology, using 2,4-dinitrobenzaldehyde (2,4-DNB) to cause a rapid in situ transformation of 5 to the Schiff base 9, with the latter more readily detectable by UHPLC-DAD (400 nm) and HPLC-MS analyses. Moreover, we demonstrate that during cultivation 5 is retained in fungal mycelia, and it is only when solvent extraction disrupts mycelia that 5 is released to come in contact with the furans 7–8 (which are themselves produced by thermal transformation of carbohydrates during media autoclaving prior to fungal inoculation). Significantly, on contact, 5 undergoes a spontaneous condensation with 7–8 to yield the Schiff base prolinimines 1–2, respectively. Observations made during this study prompted us to reflect on what it is to be a natural product (i.e., 5), versus an artifact (i.e., 1–2), versus a media component (i.e., 7–8).

Mohamed, O. G., Z. G. Khalil, and R. J. Capon, "N-Amino-l-Proline Methyl Ester from an Australian Fish Gut-Derived Fungus: Challenging the Distinction between Natural Product and Artifact", Marine drugs, vol. 19, issue 3: Multidisciplinary Digital Publishing Institute, pp. 151, 2021. Abstract
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Mohamed, O. G., Z. G. Khalil, V. Santiago, and R. J. Capon, "Metarhizides A–C and metarhizosides A–B: PKS-NRPS macrolides and aromatic glycosides from an Australian fish gut-derived fungus, Metarhizium sp. CMB-F624", Tetrahedron, vol. 113: Pergamon, pp. 132759, 2022. Abstract
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Yancey, C. E., D. J. Smith, P. A. Den Uyl, O. G. Mohamed, F. Yu, S. A. Ruberg, J. D. Chaffin, K. D. Goodwin, A. Tripathi, and D. H. Sherman, "Metagenomic and Metatranscriptomic Insights into Population Diversity of Microcystis Blooms: Spatial and Temporal Dynamics of mcy Genotypes, Including a Partial Operon That Can Be Abundant and Expressed", Applied and environmental microbiology: American Society for Microbiology 1752 N St., NW, Washington, DC, pp. e02464-21, 2022. Abstract
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Eid, O., M. A. Salem, O. G. Mohamed, S. Ezzat, A. Tripathi, M. A. Ewida, A. ElSayed, E. Abdel-Sattar, and W. M. Elkady, "Metabolomic profiling of barley extracts obtained via different solvents and evaluation of their anti-inflammatory efficacy", Food Bioscience, vol. 61: Elsevier, pp. 104682, 2024. Abstract
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Yancey, C. E., L. Hart, S. Hefferan, O. G. Mohamed, S. A. Newmister, A. Tripathi, D. H. Sherman, and G. J. Dick, "Metabologenomics reveals strain-level genetic and chemical diversity of Microcystis secondary metabolism", Msystems, vol. 9, issue 7: American Society for Microbiology 1752 N St., NW, Washington, DC, pp. e00334-24, 2024. Abstract
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Ibrahim, R. M., P. M. Abdel-Baki, O. G. Mohamed, A. A. Al-karmalawy, A. Tripathi, and R. A. El-Shiekh, "Metabolites profiling, in-vitro and molecular docking studies of five legume seeds for Alzheimer’s disease", Scientific Reports, vol. 14, issue 1: Nature Publishing Group UK London, pp. 19637, 2024. Abstract
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Abdelbaset, S., I. M. Ayoub, O. G. Mohamed, A. Tripathi, O. A. Eldahshan, and D. M. El-Kersh, "Metabolic profiling of Vitex Pubescens Vahl bark via UPLC-ESI-QTOF/MS/MS analysis and evaluation of its antioxidant and acetylcholinesterase inhibitory activities", BMC Complementary Medicine and Therapies, vol. 24, issue 1: BioMed Central London, pp. 232, 2024. Abstract
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Hassan, Y. R., R. A. El-Shiekh, H. M. El Hefnawy, O. G. Mohamed, K. Abu-Elfotuh, A. M. Hamdan, A. Darwish, A. M. H. Gowifel, A. Tripathi, and C. G. Michael, "A mechanistic exploration of the metabolome of African mango seeds and its potential to alleviate cognitive impairment induced by high-fat/high-carbohydrate diets: Involvement of PI3K/AKT/GSK-3β/CREB, PERK/CHOP/Bcl-2, and AMPK/SIRT-1/mTOR Axes.", Journal of Ethnopharmacology, vol. 324: Elsevier, pp. 117747, 2024. Abstract
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Mohamed, O. G., Z. G. Khalil, A. A. Salim, H. Cui, A. Blumenthal, and R. J. Capon, "Lincolnenins A–D: Isomeric Bactericidal Bianthracenes from Streptomyces lincolnensis", The Journal of Organic ChemistryThe Journal of Organic Chemistry, vol. 86, issue 16: American Chemical Society, pp. 11011 - 11018, 2021. AbstractWebsite
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Mohamed, O. G., Z. G. Khalil, A. A. Salim, H. Cui, A. Blumenthal, and R. J. Capon, "Lincolnenins A–D: Isomeric bactericidal bianthracenes from Streptomyces lincolnensis", The Journal of Organic Chemistry, vol. 86, issue 16: American Chemical Society, pp. 11011-11018, 2020. Abstract
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Ibrahim, R. M., R. A. El-Shiekh, O. G. Mohamed, A. A. Al-karmalawy, A. Tripathi, and P. M. Abdel-Baki, "LC/MS-Based Metabolomics Reveals Chemical Variations of Two Broccoli Varieties in Relation to Their Anticholinesterase Activity: In vitro and In silico Studies", Plant Foods for Human Nutrition: Springer US New York, pp. 1-8, 2024. Abstract
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