Publications

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2023
Nephthea sp. inhibits biofilm, DNA gyrase, HSP90, and DHFR: in vitro, in silico, and pharmacokinetics studies, Hassan, Nevine H., El-Hawary Seham S., Emam Mahmoud, Safwat Nesreen A., Rabeh Mohamed A., Abdelmohsen Usama Ramadan, and Selim Nabil M. , Natural Product Research, Volume 37, p.3896-3901, (2023) nephthea_sp_inhibits_biofilm_dna_gyrase_hsp90_and_dhfr_in_vitro_in_silico_and_pharmacokinetics_studies.pdf
Pectin Nanoparticle-Loaded Soft Coral Nephthea sp. Extract as In Situ Gel Enhances ChronicWound Healing: In Vitro, In Vivo, and In Silico Studies, Hassan, Nevine H., S.El-Hawary Seham, Emam Mahmoud, Rabeh Mohamed A., Tantawy Mohamed A., Seif Mohamed, Abd-Elal RadwaM. A., Bringmann Gerhard, Abdelmohsen Usama Ramadan, and Selim NabilM. , pharmaceuticals, Volume 16, p.1-26, (2023) pharmaceuticals-16-00957-v2.pdf
2022
Green Biosynthesis of Silver Nanoparticles Using Annona glabra and Annona squamosa Extracts with Antimicrobial, Anticancer, Apoptosis Potentials, Assisted by In Silico Modeling, and Metabolic Profiling, Mokhtar, Fatma A., b Selim Nabil M., b; Elhawary Seham S., c Abd El Hadi Soha R., Hetta Mona H., Albalawi Marzough, f; Shati Ali A., f Alfaifi Mohammad Y., g Elbehairi, Serag Eldin I. f, h Fahmy Lamiaa I., et al. , pharmaceuticals, Volume 15, Issue 11, p.1-21, (2022) green-biosynthesis-of-silver-nanoparticles-using-annona-glabra-and-annona-squamosa-extracts-with-antimicrobial-anticancer-apoptosis-potentials-assisted-by-in-silico-modeling-and-metabolic-profilingpharmaceuticals.pdf
Metabolomics‑based profiling of 4 avocado varieties using HPLC–MS/ MS and GC/MS and evaluation of their antidiabetic activity, Inas Y. Younis1, 5, Khattab Amira R., Selim Nabil M., Sobeh3 Mansour, Elhawary1 Seham S., and Bishbishy4 Mahitab El H. , Scientific Reports, Volume 12:4966, p.1-16, (2022) metabolomics-based_profiling_of_4_avocado_varietie.pdf
Phytochemical profling and anti‑fbrotic activities of Plumbago indica L. and Plumbago auriculata Lam. in thioacetamide‑induced liver fbrosis in rats, Selim1*, Nabil Mohamed, Mina Michael Melk 1, Melek2 Farouk Rasmy, Saleh3 Dalia Osama, & Mansour Sobeh4, and El‑Hawary1 Seham S. , Scientific Reports, Volume 12:9864, p.1-12, (2022) s41598-022-13718-9.pdf
Potential Inhibitors of CYP51 Enzyme in Dermatophytes by Red Sea Soft Coral Nephthea sp.: In Silico and Molecular Networking Studies, Hassan, Nevine H., El-Hawary Seham S., Emam Mahmoud, Rabeh Mohamed A., Abdelmohsen Usama Ramadan, and Selim Nabil M. , ACS Omega, Volume 7, p.13808−13817, (2022) acsomega.2c00063.pdf
2021
Antiviral Activity of Zinc Oxide Nanoparticles Mediated by Plumbago indica L. Extract Against Herpes Simplex Virus Type 1 (HSV-1), Melk, Mina Michael, El-Hawary Seham S., Melek Farouk Rasmy, Saleh Dalia Osama, Ali Omar M., Raey Mohamed El A., and Selim Nabil Mohamed , International Journal of Nanomedicine , Volume 16, p.8221–8233, (2021) ijn-339404-antiviral-activity-of-zinc-oxide-nanoparticles-mediated-by-p.pdf
Comparative phytochemical and biological studies of lipoidal matter of Ipomoea tricolor (Cav.) and Ipomoea fistulosa (Mart. Ex Choisy ) growing in Egypt, Hawary1, Seham Salah El, Ibrahim2 Nabaweya Ali, Aly3 Hanan Farouk, Matloub Azza Abd Elmged, Dosoky Magdy Mohammed, Deabes Doaa Abd Elhady, and Selim1* Nabil Mohamed , Egyptian Journal of Chemistry, Volume 64, p.1845 - 1857, (2021) ejchem_volume_64_issue_4_pages_1845-1857.pdf
Cytotoxic Plumbagin‑5‑O‑α‑l‑Rhamnopyranoside from Plumbago indica, Mina Michael Melk 1, El‑Hawary1 Seham Salah El‑deen, Melek2 Farouk Rasmy, Saleh3 Dalia Osama, and Selim1 Nabil Mohamed , Revista Brasileira de Farmacognosia, Volume 31, p.838–841, (2021) melk2021_article_cytotoxicplumbagin-5-o-a-l-rha_1.pdf
Nano Zinc Oxide Green-Synthesized from Plumbago auriculata Lam. Alcoholic Extract, Mina Michael Melk 1, El-Hawary Seham S., Melek Farouk Rasmy, Saleh Dalia Osama, Ali Omar M., Raey Mohamed El A., and Selim Nabil Mohamed , Plants 2021, 10, 2447, Volume 10, 2447, p.1-14, (2021) plants-10-02447.pdf
2020
Impact ofWashingtonia robusta Leaves on Gamma Irradiation-Induced Hepatotoxicity in Rats and Correlation with STING Pathway and Phenolic Compositio, Selim, Nabil M., El-Hawary Seham S., Zalabani Soheir El M., Shamma Rehab Nabil, Mahdy Nariman El Sayed, Sherif Noheir H., Fahmy Hanan A., Mekkawy Mai H., Yasri Abdelaziz, and Sobeh Mansour , pharmaceuticals, Volume 13, 320, p.1-24, (2020)
2019
Chrysophanol, Physcion, Hesperidin and Curcumin Modulate the Gene Expression of Pro-Inflammatory Mediators Induced by LPS in HepG2: In Silico and Molecular Studies, Selim, Nabil Mohamed, Elgazar Abdullah Abdurrahman, Abdel-Hamid Nabil Mohie, El-Magd Mohammed Rizk Abu, Yasri Aziz, Hefnawy Hala Mohamed El, and Sobeh Mansour , Antioxidants, Volume 8, Issue 9, p.1-23, (2019) antioxidants-08-00371-v2_1.pdf
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Phenolic Constituents of Chrysophyllum oliviforme L. Leaf Down-Regulate TGF- Expression and Ameliorate CCl4-Induced Liver Fibrosis: Evidence from In Vivo and In Silico Studies, El-Hawary, Seham El-Din S., Zalabani Soheir El M., Selim Nabil M., Marwa A Ibrahim, A.Wahba Fatma, Badawy Shymaa El A., Mahdy Nariman El Sayed, Yasri Aziz, and Sobeh Mansour , Antioxidants, Volume 8, Issue 12, p.1-19, (2019) antioxidants-08-00646_3.pdf
2018
Isolates from Alpinia officinarum Hance attenuate LPS‐induced inflammation in HepG2: Evidence from in silico and in vitro studies, Abdullah A. Elgazar1, 2, Selim1 Nabil M., Abdel‐Hamid3 Nabil M., El‐Magd4 Mohammed A., and Hefnawy1 Hala El M. , Phytotherapy Research, Volume 32, p.1273-1288, (2018)
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2017
Polyhydroxy Sterols Isolated from the Red Sea Soft Coral Lobophytum crassum and their Cytotoxic Activity, Aboutabl, Elsayed A., Selim Nabil M., Azzam Shadia M., Michel Camilia G., F.Hegazy Mohamed, Ali Abdelhamid M., and H Ahmed A. , Natural Product Communications, Volume 12, Issue 2, p.233 - 235, (2017) npc-12-2-233-2017.pdf
2016
Biological Investigations of a New Natural Recipe Expected to Promote Healing of Superficial Burns, M, Nasef, A2 Kadry H., A Ashour M., L Nassar S., M Selim N., and A El-Raey M. , International Journal of Pharmaceutical and Clinical Research, Volume 8, Issue 8, p.1230-1239, (2016) ijpcrvol8issue8article21.pdf
PHYTOCHEMICAL COMPOSITION, IN VITRO ANTIOXIDANT AND CYTOTOXIC ACTIVITIES OF SEEDS OF CONVOLVULUS ARVENSIS LINN., Ibrahim, Taghreed A., EL-HELA ATEF A., ELHADY NEVEIN ABD M., and ABO-ELFETOH NABIL M. , International Journal of Pharma and Bio Sciences, Volume 7, Issue 2, p.107 - 116, (2016) 4985_pdf.pdf
2013
Bioactive terpenoids from the Red Sea soft coral Sinularia polydactyla., Aboutabl, El-Sayed A., Azzam Shadia M., Michel Camilia G., Selim Nabil M., Hegazy Mohamed F., Ali Abdel-Hamid A. M., and Hussein Ahmed A. , Natural product research, 2013, Volume 27, Issue 23, p.2224-6, (2013) Abstract

Chemical investigation of an ethyl acetate soluble fraction of Sinularia polydactyla (Ehrenberg) led to the isolation of three known terpenoides, two of them sterols, 24-methylcholestane-3β,5α,6β,25-tetrol 25-monoacetate (1), 24-methylcholestane-5-en-3β,25-diol (2), in addition to a cembranoid diterpene, durumolide C (3), for the first time. The cytotoxicity and antimicrobial activities of the ethyl acetate extract and the isolated compounds 1-3 were evaluated in vitro. Durumolide C (3) showed selective cytotoxicity against HepG2 (IC50 1.0 μg/mL), whereas 24-methylcholestane-3β,5α,6β,25-tetrol 25-monoacetate (1) showed IC50 of 6.1 and 8.2 μg/mL against Hep2 and HCT human cancer cell lines, respectively.

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