Publications

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2022
El-Safty, H., A. Ismail, R. Mohsen, A. E. El-Sahar, and M. Asaad, "Dapagliflozin diminishes memory and cognition impairment in Streptozotocin induced diabetes through its effect on Wnt/β-Catenin and CREB pathway", Brain Research Bulletin, vol. 181, pp. 109-120, 2022. AbstractWebsite
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El-Shamarka, M. E. - S., A. E. El-Sahar, M. Asaad, N. Assaf, and R. H. Sayed, "Inosine attenuates 3-nitropropionic acid-induced Huntington's disease-like symptoms in rats via the activation of the A2AR/BDNF/TrKB/ERK/CREB signaling pathway", Life Sciences, vol. 300, 2022. AbstractWebsite
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El-Ghannam, M. S., M. Asaad, N. N. Nassar, M. F. El-Yamany, and A. A. Z. El-Bahy, "Linagliptin ameliorates acetic acid-induced colitis via modulating AMPK/SIRT1/PGC-1α and JAK2/STAT3 signaling pathway in rats", Toxicology and Applied Pharmacology, vol. 438, 2022. AbstractWebsite
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Al-Madhagy, S. A., S. S. Gad, E. S. Mostafa, S. Angeloni, M. Asaad, O. M. Sabry, G. Caprioli, and S. S. El-Hawary, "A new arsenal of polyphenols to make Parkinson's disease extinct: HPLC-MS/MS profiling, very interesting MAO-B inhibitory activity and antioxidant activity of Otostegia fruticosa", Natural Product Research, 2022. AbstractWebsite
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Asaad, M., M. Y. Al-Shorbagy, and H. H. Arab, "Targeting the TLR4/NF-κΒ Axis and NLRP1/3 Inflammasomes by Rosuvastatin: A Role in Impeding Ovariectomy-Induced Cognitive Decline Neuropathology in Rats", Molecular Neurobiology, vol. 59, no. 7, pp. 4562-4577, 2022. AbstractWebsite
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2021
Arab, H. H., M. Y. Al-Shorbagy, and M. Asaad, "Activation of autophagy and suppression of apoptosis by dapagliflozin attenuates experimental inflammatory bowel disease in rats: Targeting AMPK/mTOR, HMGB1/RAGE and Nrf2/HO-1 pathways", Chemico-Biological Interactions, vol. 335, 2021. AbstractWebsite
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Fathi, D., A. I. Abulsoud, M. Asaad, N. N. Nassar, M. M. Maksimos, S. M. Rizk, and M. A. Senousy, "Agomelatine attenuates alcohol craving and withdrawal symptoms by modulating the Notch1 signaling pathway in rats", Life Sciences, vol. 284, 2021. AbstractWebsite
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El-Yamany, M. F., E. S. Zaki, S. A. Shaltout, and M. Asaad, "Bone marrow mononuclear cells boosts anti-cytogentical aberration effect of N-acetylcysteine and α-lipoic acid in rat’s liver and bone marrow: implication of oxidative and inflammatory pathways", Toxicology Mechanisms and Methods, vol. 31, no. 6, pp. 437-449, 2021. AbstractWebsite
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Ramadan, S., M. M. Sabry, M. Asaad, S. Angeloni, O. M. Sabry, G. Caprioli, and S. M. El Zalabani, "Dismantling Parkinson’s disease with herbs: MAO-B inhibitory activity and quantification of chemical constituents using HPLC-MS/MS of Egyptian local market plants", Natural Product Research, 2021. AbstractWebsite
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Saad, M. A. E., M. I. M. Fahmy, R. H. Sayed, M. F. El-Yamany, R. El-Naggar, A. A. E. Hegazy, and M. Al-Shorbagy, "Eprosartan: A closer insight into its neuroprotective activity in rats with focal cerebral ischemia–reperfusion injury", Journal of Biochemical and Molecular Toxicology, vol. 35, no. 7, 2021. AbstractWebsite
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Shawki, S. M., M. Asaad, R. M. Rahmo, W. Wadie, and H. S. El-Abhar, "Liraglutide Improves Cognitive and Neuronal Function in 3-NP Rat Model of Huntington’s Disease", Frontiers in Pharmacology, vol. 12, 2021. AbstractWebsite
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Asaad, M., M. A. Eltarzy, R. M. Abdelsalam, and M. A. E. Ahmed, "Liraglutide mends cognitive impairment by averting Notch signaling pathway overexpression in a rat model of polycystic ovary syndrome", Life Sciences, vol. 265, 2021. AbstractWebsite
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Asaad, M., M. A. E. Ahmed, N. N. Elbadawy, and N. F. Abdelkader, "Nano-ivabradine averts behavioral anomalies in Huntington's disease rat model via modulating Rhes/m-tor pathway", Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 111, 2021. AbstractWebsite
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Saleh, R. A., T. F. Eissa, D. M. Abdallah, M. Asaad, and H. S. El-Abhar, "Peganum harmala enhanced GLP-1 and restored insulin signaling to alleviate AlCl3-induced Alzheimer-like pathology model", Scientific Reports, vol. 11, no. 1, 2021. AbstractWebsite
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Emam, A. M., M. Asaad, N. A. Ahmed, and H. F. Zaki, "Vortioxetine mitigates neuronal damage by restricting PERK/eIF2α/ATF4/CHOP signaling pathway in rats subjected to focal cerebral ischemia-reperfusion", Life Sciences, vol. 283, 2021. AbstractWebsite
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2020
Helmy, H. S., M. A. Senousy, A. E. El-Sahar, R. H. Sayed, M. Asaad, and E. M. Elbaz, "Aberrations of miR-126-3p, miR-181a and sirtuin1 network mediate Di-(2-ethylhexyl) phthalate-induced testicular damage in rats: The protective role of hesperidin", Toxicology, vol. 433-434, 2020. AbstractWebsite
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El-Sahar, A. E., A. A. Rastanawi, M. F. El-Yamany, and M. Asaad, "Dapagliflozin improves behavioral dysfunction of Huntington's disease in rats via inhibiting apoptosis-related glycolysis", Life Sciences, vol. 257, 2020. AbstractWebsite
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Farouk, H., M. Asaad, S. S. Mahmoud, M. F. El-Yamany, O. A. Sharaf, R. F. Ahmed, and E. E. El-Denshary, "Effect of (+) and (-) hydroxycitric acid sterio-isomers present in natural products in counteracting insulin resistance", Egyptian Journal of Chemistry, vol. 63, no. 11, pp. 4341-4354, 2020. AbstractWebsite
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Arab, H. H., M. Asaad, A. E. El-Sahar, and M. Y. Al-Shorbagy, "Mechanistic perspective of morin protection against ketoprofen-induced gastric mucosal injury: Targeting HMGB1/RAGE/NF-κB, DJ-1/Nrf2/HO-1 and PI3K/mTOR pathways", Archives of Biochemistry and Biophysics, vol. 693, 2020. AbstractWebsite
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Saad, M. A. E. - L., M. I. M. Fahmy, M. Al-Shorbagy, N. Assaf, A. A. E. - A. Hegazy, and M. F. El-Yamany, "Nateglinide Exerts Neuroprotective Effects via Downregulation of HIF-1α/TIM-3 Inflammatory Pathway and Promotion of Caveolin-1 Expression in the Rat’s Hippocampus Subjected to Focal Cerebral Ischemia/Reperfusion Injury", Inflammation, vol. 43, no. 2, pp. 401-416, 2020. AbstractWebsite
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Yossef, R. R., M. F. Al-Yamany, M. Asaad, and A. E. El-Sahar, "Neuroprotective effects of vildagliptin on drug induced Alzheimer's disease in rats with metabolic syndrome: Role of hippocampal klotho and AKT signaling pathways", European Journal of Pharmacology, vol. 889, 2020. AbstractWebsite
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2019
Elbaz, E. M., H. S. Helmy, A. E. El-Sahar, M. Asaad, and R. H. Sayed, "Lercanidipine boosts the efficacy of mesenchymal stem cell therapy in 3-NP-induced Huntington's disease model rats via modulation of the calcium/calcineurin/NFATc4 and Wnt/β-catenin signalling pathways", Neurochemistry International, vol. 131, 2019. AbstractWebsite
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Asaad, M., A. E. El-Sahhar, H. H. Arab, and M. Y. Al-Shorbagy, "Nicorandil abates arthritic perturbations induced by complete Freund's adjuvant in rats via conquering TLR4-MyD88-TRAF6 signaling pathway", Life Sciences, vol. 218, pp. 284-291, 2019. AbstractWebsite
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Asaad, M., A. E. El-Sahar, R. H. Sayed, E. M. Elbaz, H. S. Helmy, and M. A. Senousy, "Venlafaxine Mitigates Depressive-Like Behavior in Ovariectomized Rats by Activating the EPO/EPOR/JAK2 Signaling Pathway and Increasing the Serum Estradiol Level", Neurotherapeutics, vol. 16, no. 2, pp. 404-415, 2019. AbstractWebsite
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2018
Asaad, M., A. A. Rastanawi, and M. F. El-Yamany, "Alogliptin abates memory injuries of hepatic encephalopathy induced by acute paracetamol intoxication via switching-off autophagy-related apoptosis", Life Sciences, vol. 215, pp. 11-21, 2018. AbstractWebsite
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