Acral Speckled Hypomelanosis: A Case Report and a Review of Literature.

Citation:
Azzazi, Y., M. M. Korany, and E. A. El-Nabarawy, "Acral Speckled Hypomelanosis: A Case Report and a Review of Literature.", The American Journal of dermatopathology, vol. 45, issue 6, pp. 397-399, 2023.

Abstract:

BACKGROUND: Acral speckled hypomelanosis is a very rare pigmentation disorder that appears early in life with hypopigmented macules on background of normal skin, occurring on the acral parts.

CASE REPORT: We report a 9-year-old female patient with a 3-year duration of progressive, hypopigmented, confetti-like macules occurring symmetrically on the dorsum of both hands and feet. Biopsy showed normal number of melanocytes with no evidence of macromelanosomes using special stains for melanocytes.

CONCLUSION: Acral speckled hypomelanosis is a relatively, recently, discovered entity, with only 9 cases reported to date, and our case is the 10th. The exact etiopathogenesis is not yet known.